• 한국우주과학회:학술대회논문집(한국우주과학회보)
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• 한국우주과학회 1993년도 한국우주과학회보 제2권2호
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• pp.17-17
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• 1993

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70${\pm}$1.32mmHg/min)compared to CF dialyzers(4.32${\pm}$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500,550,570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500,550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100,300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3,000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.

• 대한화학회지
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• 제43권4호
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• pp.384-385
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• 1999

$Ca^{2+}$ 이온과 $Tl^+$ 이온으로 치환되고 완전히 진공 탈수된 제올라이트 X결정 $Ca_{18}Tl_{56}Si_{100}Al_{92}O_{384}$ ($Ca_{18}Tl_{56}$-X;${\alpha}=24.883(4){\AA}$)와 $Ca_{32}Tl_{28}Si_{100}Al_{92}O_{384}$ ($Ca_{32}Tl_{28}$-X;${\alpha}=24.973(4){\AA}A$)의 구조를 21(1)TEX>$^{\circ}C$에서 입방공간군 Fd3을 사용하여 단결정 X-선 회절법으로 해석하고 그 구조를 정밀화 하였다 $Ca_{18}Tl_{56}$-X 결정은 0.045 M $Ca(NO_3)_2$와 0.005 M $TINO_3$ 혼합용액으로 흐름법을 이용하여 이온 교환하였다. $Ca_{32}Tl_{28}$-X는 이와 유사하게 0.0495 M $Ca(NO_3)_2$ 와 0.0005 M $TINO_3$ 혼합용액을 사용하였다. 각 결정은 360$^{\circ}C$, $2{\times}10^{-6}$ Torr에서 탈수시켰다. $Ca_{18}Tl_{56}$-X 및 $Ca_{32}Tl_{28}$-X 결정 구조는 각각 I > 3${\sigma}$ (I)인 382 및 472개의 회절 반사점을 사용하여 각각 $R_1=0.039,\;R_2=0.036$ 및 $R_1=0.046,\;R_2=0.045$의 최종 오차 지수 값을 얻었다. 탈수된 $Ca_{18}Tl_{56}$-X 및 $Ca_{32}Tl_{28}$-X 결정 구조에서, $Ca^{2+}$ 이온과 $Tl^+$ 이온은 서로 틀리는 6개의 결정학적 자리에 위치한다. 16개의 $Ca^{2+}$ 이온은 D6R의 중심인 팔면체 자리 I을 채운다 ($Ca_{18}Tl_{56}$-X : Ca-O=2.42(1) ${\AA}$ 및 O-Ca-O=93.06(4)$^{\circ}$; $Ca_{32}Tl_{28}$-X Ca-O=2.40(1) ${\AA}$ 및 O-Ca-O=93.08(3)$^{\circ}$). $Ca_{18}Tl_{56}$-X 구조에서는 2개의 $Ca^{2+}$ 이온은 자리 II (Ca-O=2.35(2) ${\AA}$ 및 O-Ca-O=111.69(2)$^{\circ}$)를 점유하고 26개의 $Tl^+$ 이온은 큰 동공 내 마주보는 S6R의 자리 II에 점유한다. 각기 3개의 산소로 만들어지는 평면으로부터 1.493 ${\AA}$ 떨어져 있다(Tl-O=2.70(8)${\AA}$ 및 O-Tl-O=92.33(4)$^{\circ}$). 약 4개의 $Tl^+$ 이온은 세 개의 산소로 만들어지는 평면으로부터 소다라이트 동공쪽으로 1.695${\AA}$ 떨어진 자리 II에 위치해 있다(Tl-O=2.81 (1) ${\AA}$ 및 O-Tl-O=87.48(3)$^{\circ}$). 나머지 26개의 $Tl^+$ 이온들은 자리 III'에 분포된다(Tl-O=2.82 (1) ${\AA}$ 및 Tl-O=2.88(3) ${\AA}$). Ca_{32}Tl_{28}$-X 결정 구조에서는 16개의 $Ca^{2+}$ 이온과 15개의 $Tl^+$ 이온들이 자리 II를 점유하고 있다(Ca-O=2.26(1) ${\AA}$ 및 O-Ca-O=119.14(4)$^{\circ}$; Tl-O=2.70(1) ${\AA}$ 및 O-Tl-O=92.38$^{\circ}$). 한 개의 $Tl^+$ 이온들은 자리 II'를 점유한다. 나머지 12개의 $Tl^+$ 이온들은 자리IlI'에 분포된다.

• 한국결정학회지
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• 제8권1호
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• pp.6-14
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• 1997

제올라이트 X에 $Sr^{2+}$와 $K^+$ 이온이 교환된 $Sr_{31}K_{30}-X$와 $Sr^{2+}$와 $Tl^+$ 이온이 교환된 $Sr_{8.5}Tl_{75}$의 결정구조를 공간군 Fd3로 $21(1)^{\circ}C$에서 단결정 X선 결정학적 방법으로 해석하였다. 각각의 결정은 $Sr(ClO_4)_2$와 (K 혹은 Tl)$NO_3$의 몰 비가 1 : 5인 용액을 사용해서 흐름 법으로 5일 동안 이온 교환시키고 $360^{\circ}C$에서 진공탈수 시켜 두 결정을 얻었다. 이들 결정은 회절강도가 $I>2{\sigma}(I)$인 293개와 351개의 회절반사를 사용하여 최종오차인자가 $R_1=0.072,\;R_w=0.057$과 $R_l= 0.058,\;R_w=0.044$까지 각각 정밀화하였다. $Sr_{31}K_{30}-X$결정에서 $Sr^{2+}$ 이온과 $K^+$ 이온은 모두 다섯 개의 서로 다른 결정학적 자리에 존재하였다. 단위세포당 16개의 $Sr^{2+}$ 이온은 결정학적 자리 I인 D6R의 중심에 각각 위치하고 D6R 모두를 채우고 있다. 나머지 15개의 $Sr^{2+}$ 이온과 17개의 $K^+$ 이온은 큰 동공 속에 있는 결정학적 자리II에 위치하고 세 개의 산소이온이 이루는 평면에서 각각 $0.45{\AA},\;1.06{\AA}$ 큰 동공속으로 이동하여 위치하고 골조산소와 결합거리는 각각 $2.45(1){\AA},\;2.64(1){\AA}$이다. 13개의 $K^+$ 이온은 두 개의 다른 결정학적자리 III'에 위치하며 인접한 산소와의 결합거리는 각각 $2.88(7){\AA}$와 $3.11(10){\AA}$이다. $Sr_{8.5}Tl_{75}-X$에서는 $Sr^{2+}$이온과 $Tl^+$ 이온이 역시 다섯 개의 서로 다른 결정학적 자리에 위치한다. 약 8.5개의 $Sr^{2+}$ 이온은 결정학적 자리 I에 있으며, 15개의 $Tl^+$ 이온은 D6R의 3회 전축상의 소다라이트내에 있는 결정학적 자리 I'에 있다. 이 $Tl^+$ 이온은 골조산소와의 결합거리가 $2.70(2){\AA}$이며 세 개의 산소가 이루는 평면에서 $1.68{\AA}$ 소다라이트내로 이동하여 위치한다. 32개의 $Tl^{+}$ 이온은 결정학적 자리 II에 존재하고 있으며 산소와의 결합거리를 $2.70(1){\AA}$을 유지하면서 큰 동공속으로 $1.48{\AA}$ 이동하여 위치한다. 약 18개의 $Tl^+$ 이온은 결정학적 자리III에, 또 다른 10개의 $Tl^+$ 이온은 결정학적 자리III'에 존재하고 골조 산소와 각각 $2.86(2){\AA},\;2.96(4){\AA}$의 결합거리를 이룬다.

• 지능정보연구
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• 제25권3호
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• pp.161-177
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• 2019

질의응답 시스템은 크게 사용자의 질의를 분석하는 방법인 질의 분석과 문서 내에서 적합한 정답을 추출하는 방법인 정답 추출로 이루어지며, 두 방법에 대한 다양한 연구들이 진행되고 있다. 본 연구에서는 문장의 의존 구문 분석 결과를 이용하여 질의응답 시스템 내 정답 추출의 성능 향상을 위한 연구를 진행한다. 정답 추출의 성능을 높이기 위해서는 문장의 문법적인 정보를 정확하게 반영할 필요가 있다. 한국어의 경우 어순 구조가 자유롭고 문장의 구성 성분 생략이 빈번하기 때문에 의존 문법에 기반한 의존 구문 분석이 적합하다. 기존에 의존 구문 분석을 질의응답 시스템에 반영했던 연구들은 구문 관계 정보나 구문 형식의 유사도를 정의하는 메트릭을 사전에 정의해야 한다는 한계점이 있었다. 또 문장의 의존 구문 분석 결과를 트리 형태로 표현한 후 트리 편집 거리를 계산하여 문장의 유사도를 계산한 연구도 있었는데 이는 알고리즘의 연산량이 크다는 한계점이 존재한다. 본 연구에서는 구문 패턴에 대한 정보를 사전에 정의하지 않고 정답 후보 문장을 그래프로 나타낸 후 그래프 정보를 효과적으로 반영할 수 있는 Graph2Vec을 활용하여 입력 자질을 생성하였고, 이를 정답 추출모델의 입력에 추가하여 정답 추출 성능 개선을 시도하였다. 의존 그래프를 생성하는 단계에서 의존 관계의 방향성 고려 여부와 노드 간 최대 경로의 길이를 다양하게 설정하며 자질을 생성하였고, 각각의 경우에 따른 정답추출 성능을 비교하였다. 본 연구에서는 정답 후보 문장들의 신뢰성을 위하여 웹 검색 소스를 한국어 위키백과, 네이버 지식백과, 네이버 뉴스로 제한하여 해당 문서에서 기존의 정답 추출 모델보다 성능이 향상함을 입증하였다. 본 연구의 실험을 통하여 의존 구문 분석 결과로 생성한 자질이 정답 추출 시스템 성능 향상에 기여한다는 것을 확인하였고 해당 자질을 정답 추출 시스템뿐만 아니라 감성 분석이나 개체명 인식과 같은 다양한 자연어 처리 분야에 활용 될 수 있을 것으로 기대한다.

• 공연문화연구
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• 제38호
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• pp.349-383
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• 2019

이 글에서 주목하는 것은 동해안별신굿에서 무당과 마을 사람들이 직접 관계 하면서 생성되는 '축원-굿춤'판이다. 굿판의 흥을 돋우기 위해 굿거리의 말미 또는 굿거리와 굿거리 사이에 집단적으로 벌이는 '허튼춤판'과는 달리, '축원-굿춤'은 매 굿거리에서 축원무가 구연 중에 개별적이고 반복적으로 생성되므로 별신굿을 이해하는 데 매우 중요한 춤이다. 그러므로 '축원-굿춤'판의 생성배경을 살피고, 그것이 어떠한 사회적 성격을 지니는지에 대해 살펴 볼 필요가 있겠다. 산업혁명 이후 기계제공업(機械制工業)이 확립되면서 많은 수공업 생산자들이 소비자의 입장으로 바뀌게 되었으며, 자본주의적 생산양식과 분배법칙은 다양한 마을굿에도 영향을 미치게 되었다. 즉 굿에 필요한 제반시설과 도구 그리고 행위 등이 자본주의적 생산과 소비 체제 속에 편입된 것이다. 이로 인해 전통적으로 굿에서 '정성'을 상징했던 시간과 행위 그리고 제물 등이 지닌 의미는 기계의 대량생산화와 자본의 흐름 속에 희석되었다. 그리고 별신 굿 기간 동안 행해지는 모든 가무악 연행은 자본/노동적 가치로 산출될 수있는데, 특히 '축원'이 '춤'으로 이어질 경우, 무당은 자본적 이익[별비]과 노동의 가치를 획득하게 된다. 그러므로 넓은 의미에서 '재수굿'에 해당되는 '축원-굿춤'판에 포함된 '축원[말]과 춤[몸짓]'의 생산 활동은 동해안별신굿이 갖는 전통적인 제의적 맥락과 더불어 한국 자본주의의 문화적 맥락 속에 놓여있다고 할 수 있겠다. '축원-굿춤'의 특징을 요약하면 다음과 같다. 첫째, '축원-굿춤'은 '마을공동체→소집단별 경쟁→개별적 경쟁'으로 이어진다. 둘째, '축원 무가' 구연이 지속적으로 반복될수록 이와 관련된 연행이 '굿춤'으로 이어질 가능성은 점점 줄어들게 된다. 셋째, 다양한 축원의 대상들 중에서 특히 어촌 사람들의 생업 활동과 관련된 직간접적인 공감대가 형성되었을 경우 '축원→굿춤'으로 잘 연결된다. 넷째, 축원의 범주에 포함되지 못한 집단은 반복적으로 '축원-굿춤'판에서 소외될 수 있다.

• 유통과학연구
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• 제8권3호
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• pp.49-56
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• 2010

At the initial stage of Internet advertising, banner advertising came into fashion. As the Internet developed into a central part of daily lives and the competition in the on-line advertising market was getting fierce, there was not enough space for banner advertising, which rushed to portal sites only. All these factors was responsible for an upsurge in advertising prices. Consequently, the high-cost and low-efficiency problems with banner advertising were raised, which led to an emergence of keyword advertising as a new type of Internet advertising to replace its predecessor. In the beginning of 2000s, when Internet advertising came to be activated, display advertisement including banner advertising dominated the Net. However, display advertising showed signs of gradual decline, and registered minus growth in the year 2009, whereas keyword advertising showed rapid growth and started to outdo display advertising as of the year 2005. Keyword advertising refers to the advertising technique that exposes relevant advertisements on the top of research sites when one searches for a keyword. Instead of exposing advertisements to unspecified individuals like banner advertising, keyword advertising, or targeted advertising technique, shows advertisements only when customers search for a desired keyword so that only highly prospective customers are given a chance to see them. In this context, it is also referred to as search advertising. It is regarded as more aggressive advertising with a high hit rate than previous advertising in that, instead of the seller discovering customers and running an advertisement for them like TV, radios or banner advertising, it exposes advertisements to visiting customers. Keyword advertising makes it possible for a company to seek publicity on line simply by making use of a single word and to achieve a maximum of efficiency at a minimum cost. The strong point of keyword advertising is that customers are allowed to directly contact the products in question through its more efficient advertising when compared to the advertisements of mass media such as TV and radio, etc. The weak point of keyword advertising is that a company should have its advertisement registered on each and every portal site and finds it hard to exercise substantial supervision over its advertisement, there being a possibility of its advertising expenses exceeding its profits. Keyword advertising severs as the most appropriate methods of advertising for the sales and publicity of small and medium enterprises which are in need of a maximum of advertising effect at a low advertising cost. At present, keyword advertising is divided into CPC advertising and CPM advertising. The former is known as the most efficient technique, which is also referred to as advertising based on the meter rate system; A company is supposed to pay for the number of clicks on a searched keyword which users have searched. This is representatively adopted by Overture, Google's Adwords, Naver's Clickchoice, and Daum's Clicks, etc. CPM advertising is dependent upon the flat rate payment system, making a company pay for its advertisement on the basis of the number of exposure, not on the basis of the number of clicks. This method fixes a price for advertisement on the basis of 1,000-time exposure, and is mainly adopted by Naver's Timechoice, Daum's Speciallink, and Nate's Speedup, etc, At present, the CPC method is most frequently adopted. The weak point of the CPC method is that advertising cost can rise through constant clicks from the same IP. If a company makes good use of strategies for maximizing the strong points of keyword advertising and complementing its weak points, it is highly likely to turn its visitors into prospective customers. Accordingly, an advertiser should make an analysis of customers' behavior and approach them in a variety of ways, trying hard to find out what they want. With this in mind, her or she has to put multiple keywords into use when running for ads. When he or she first runs an ad, he or she should first give priority to which keyword to select. The advertiser should consider how many individuals using a search engine will click the keyword in question and how much money he or she has to pay for the advertisement. As the popular keywords that the users of search engines are frequently using are expensive in terms of a unit cost per click, the advertisers without much money for advertising at the initial phrase should pay attention to detailed keywords suitable to their budget. Detailed keywords are also referred to as peripheral keywords or extension keywords, which can be called a combination of major keywords. Most keywords are in the form of texts. The biggest strong point of text-based advertising is that it looks like search results, causing little antipathy to it. But it fails to attract much attention because of the fact that most keyword advertising is in the form of texts. Image-embedded advertising is easy to notice due to images, but it is exposed on the lower part of a web page and regarded as an advertisement, which leads to a low click through rate. However, its strong point is that its prices are lower than those of text-based advertising. If a company owns a logo or a product that is easy enough for people to recognize, the company is well advised to make good use of image-embedded advertising so as to attract Internet users' attention. Advertisers should make an analysis of their logos and examine customers' responses based on the events of sites in question and the composition of products as a vehicle for monitoring their behavior in detail. Besides, keyword advertising allows them to analyze the advertising effects of exposed keywords through the analysis of logos. The logo analysis refers to a close analysis of the current situation of a site by making an analysis of information about visitors on the basis of the analysis of the number of visitors and page view, and that of cookie values. It is in the log files generated through each Web server that a user's IP, used pages, the time when he or she uses it, and cookie values are stored. The log files contain a huge amount of data. As it is almost impossible to make a direct analysis of these log files, one is supposed to make an analysis of them by using solutions for a log analysis. The generic information that can be extracted from tools for each logo analysis includes the number of viewing the total pages, the number of average page view per day, the number of basic page view, the number of page view per visit, the total number of hits, the number of average hits per day, the number of hits per visit, the number of visits, the number of average visits per day, the net number of visitors, average visitors per day, one-time visitors, visitors who have come more than twice, and average using hours, etc. These sites are deemed to be useful for utilizing data for the analysis of the situation and current status of rival companies as well as benchmarking. As keyword advertising exposes advertisements exclusively on search-result pages, competition among advertisers attempting to preoccupy popular keywords is very fierce. Some portal sites keep on giving priority to the existing advertisers, whereas others provide chances to purchase keywords in question to all the advertisers after the advertising contract is over. If an advertiser tries to rely on keywords sensitive to seasons and timeliness in case of sites providing priority to the established advertisers, he or she may as well make a purchase of a vacant place for advertising lest he or she should miss appropriate timing for advertising. However, Naver doesn't provide priority to the existing advertisers as far as all the keyword advertisements are concerned. In this case, one can preoccupy keywords if he or she enters into a contract after confirming the contract period for advertising. This study is designed to take a look at marketing for keyword advertising and to present effective strategies for keyword advertising marketing. At present, the Korean CPC advertising market is virtually monopolized by Overture. Its strong points are that Overture is based on the CPC charging model and that advertisements are registered on the top of the most representative portal sites in Korea. These advantages serve as the most appropriate medium for small and medium enterprises to use. However, the CPC method of Overture has its weak points, too. That is, the CPC method is not the only perfect advertising model among the search advertisements in the on-line market. So it is absolutely necessary that small and medium enterprises including independent shopping malls should complement the weaknesses of the CPC method and make good use of strategies for maximizing its strengths so as to increase their sales and to create a point of contact with customers.

• 인터넷정보학회논문지
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• 제14권6호
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• pp.71-84
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• 2013

컴퓨터 시스템 운용 간에 발생하는 많은 정보들이 기록되는 로그데이터는 컴퓨터 시스템 운용 점검, 프로세스의 최적화, 사용자 최적화 맞춤형 제공 등 다방면으로 활용되고 있다. 본 논문에서는 다양한 종류의 로그데이터들 중에서 은행에서 발생하는 대용량의 로그데이터를 처리하기 위한 클라우드 환경 하에서의 MongoDB 기반 비정형 로그 처리시스템을 제안한다. 은행업무간 발생하는 대부분의 로그데이터는 고객의 업무처리 프로세스 간에 발생하며, 고객 업무 프로세스 처리에 따른 로그데이터를 수집, 저장, 분류, 분석하기 위해서는 별도로 로그데이터를 처리하는 시스템을 구축해야만 한다. 하지만 기존 컴퓨팅환경 하에서는 폭발적으로 증가하는 대용량 비정형 로그데이터 처리를 위한 유연한 스토리지 확장성 기능, 저장된 비정형 로그데이터를 분류, 분석 처리할 수 있는 기능을 구현하기가 매우 어렵다. 이에 따라 본 논문에서는 클라우드 컴퓨팅 기술을 도입하여 기존 컴퓨팅 인프라 환경의 분석 도구 및 관리체계에서 처리하기 어려웠던 비정형 로그데이터를 처리하기 위한 클라우드 환경기반의 로그데이터 처리시스템을 제안하고 구현하였다. 제안한 본 시스템은 IaaS(Infrastructure as a Service) 클라우드 환경을 도입하여 컴퓨팅 자원의 유연한 확장성을 제공하며 실제로, 로그데이터가 장기간 축적되거나 급격하게 증가하는 상황에서 스토리지, 메모리 등의 자원을 신속성 있고 유연하게 확장을 할 수 있는 기능을 포함한다. 또한, 축적된 비정형 로그데이터의 실시간 분석이 요구되어질 때 기존의 분석도구의 처리한계를 극복하기 위해 본 시스템은 하둡 (Hadoop) 기반의 분석모듈을 도입함으로써 대용량의 로그데이터를 빠르고 신뢰성 있게 병렬 분산 처리할 수 있는 기능을 제공한다. 게다가, HDFS(Hadoop Distributed File System)을 도입함으로써 축적된 로그데이터를 블록단위로 복제본을 생성하여 저장관리하기 때문에 본 시스템은 시스템 장애와 같은 상황에서 시스템이 멈추지 않고 작동할 수 있는 자동복구 기능을 제공한다. 마지막으로, 본 시스템은 NoSQL 기반의 MongoDB를 이용하여 분산 데이터베이스를 구축함으로써 효율적으로 비정형로그데이터를 처리하는 기능을 제공한다. MySQL과 같은 관계형 데이터베이스는 복잡한 스키마 구조를 가지고 있기 때문에 비정형 로그데이터를 처리하기에 적합하지 않은 구조를 가지고 있다. 또한, 관계형 데이터베이스의 엄격한 스키마 구조는 장기간 데이터가 축적되거나, 데이터가 급격하게 증가할 때 저장된 데이터를 분할하여 여러 노드에 분산시키는 노드 확장이 어렵다는 문제점을 가지고 있다. NoSQL은 관계형 데이터베이스에서 제공하는 복잡한 연산을 지원하지는 않지만 데이터가 빠르게 증가할 때 노드 분산을 통한 데이터베이스 확장이 매우 용이하며 비정형 데이터를 처리하는데 매우 적합한 구조를 가지고 있는 비관계형 데이터베이스이다. NoSQL의 데이터 모델은 주로 키-값(Key-Value), 컬럼지향(Column-oriented), 문서지향(Document-Oriented)형태로 구분되며, 제안한 시스템은 스키마 구조가 자유로운 문서지향(Document-Oriented) 데이터 모델의 대표 격인 MongoDB를 도입하였다. 본 시스템에 MongoDB를 도입한 이유는 유연한 스키마 구조에 따른 비정형 로그데이터 처리의 용이성뿐만 아니라, 급격한 데이터 증가에 따른 유연한 노드 확장, 스토리지 확장을 자동적으로 수행하는 오토샤딩 (AutoSharding) 기능을 제공하기 때문이다. 본 논문에서 제안하는 시스템은 크게 로그 수집기 모듈, 로그 그래프생성 모듈, MongoDB 모듈, Hadoop기반 분석 모듈, MySQL 모듈로 구성되어져 있다. 로그 수집기 모듈은 각 은행에서 고객의 업무 프로세스 시작부터 종료 시점까지 발생하는 로그데이터가 클라우드 서버로 전송될 때 로그데이터 종류에 따라 데이터를 수집하고 분류하여 MongoDB 모듈과 MySQL 모듈로 분배하는 기능을 수행한다. 로그 그래프생성 모듈은 수집된 로그데이터를 분석시점, 분석종류에 따라 MongoDB 모듈, Hadoop기반 분석 모듈, MySQL 모듈에 의해서 분석되어진 결과를 사용자에게 웹 인터페이스 형태로 제공하는 역할을 한다. 실시간적 로그데이터분석이 필요한 로그데이터는 MySQL 모듈로 저장이 되어 로그 그래프생성 모듈을 통하여 실시간 로그데이터 정보를 제공한다. 실시간 분석이 아닌 단위시간당 누적된 로그데이터의 경우 MongoDB 모듈에 저장이 되고, 다양한 분석사항에 따라 사용자에게 그래프화해서 제공된다. MongoDB 모듈에 누적된 로그데이터는 Hadoop기반 분석모듈을 통해서 병렬 분산 처리 작업이 수행된다. 성능 평가를 위하여 로그데이터 삽입, 쿼리 성능에 대해서 MySQL만을 적용한 로그데이터 처리시스템과 제안한 시스템을 비교 평가하였으며 그 성능의 우수성을 검증하였다. 또한, MongoDB의 청크 크기별 로그데이터 삽입 성능평가를 통해 최적화된 청크 크기를 확인하였다.

• 대한의용생체공학회:의공학회지
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• 제6권2호
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• pp.1-8
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• 1985

The wall shear stress in the vicinity of end-to end anastomoses under steady flow conditions was measured using a flush-mounted hot-film anemometer(FMHFA) probe. The experimental measurements were in good agreement with numerical results except in flow with low Reynolds numbers. The wall shear stress increased proximal to the anastomosis in flow from the Penrose tubing (simulating an artery) to the PTFE: graft. In flow from the PTFE graft to the Penrose tubing, low wall shear stress was observed distal to the anastomosis. Abnormal distributions of wall shear stress in the vicinity of the anastomosis, resulting from the compliance mismatch between the graft and the host artery, might be an important factor of ANFH formation and the graft failure. The present study suggests a correlation between regions of the low wall shear stress and the development of anastomotic neointimal fibrous hyperplasia(ANPH) in end-to-end anastomoses. 30523 T00401030523 ^x Air pressure decay(APD) rate and ultrafiltration rate(UFR) tests were performed on new and saline rinsed dialyzers as well as those roused in patients several times. C-DAK 4000 (Cordis Dow) and CF IS-11 (Baxter Travenol) reused dialyzers obtained from the dialysis clinic were used in the present study. The new dialyzers exhibited a relatively flat APD, whereas saline rinsed and reused dialyzers showed considerable amount of decay. C-DAH dialyzers had a larger APD(11.70$\pm$1.32mmHg/min)compared to CF dialyzers(4.32$\pm$0.55mmHg/min)(p<0.05). However, there was no observable difference in the UFR between the two dialyzers. Neither APD nor UFR showed any significant increase with an increasing number of reuses for up to more than 20reuses. A substantial number of failures observed in APD(larger than 20mmHe/min)on the reused dialyzers(2 out of 40 CP and S out 26 C-DAK) were attributed to the Possible damage on the fibers. The CF 15-11 HFDs which failed APD test did not show changes in the UFR compared to normal dialyzers indicating that APD is a more sensitive test than UFR test to evaluate the integrity of the fibers. 30527 T00401030527 ^x For quantitative measurement of reflected light from a clinical diagnostic strip, a prototype old reflectance photometer was designed. The strip loader and cassette were made to obtain more accurate reflectance parameters. The strip was illuminated at 45˚c through optical fiber and the intensity of reflected light was determined at rectanguLat angle using a photodiode. The kubelka-munk coefficient and reflection optical density were determined ar four different wavelengths(500, 550, 570 and 610nm) for blood glucose strip. For higher concentration than 300mg/41 about glucose, a saturation state of abforbance was observed at 500, 550 and 570nm. The correlation between glucose concentration and parameters was the best at 610nm. 30535 T00401030535 ^x Radiation-induced fibrosarcoma tumors were grown on the flanks of C3H mice. The mice were divided into two groups. One group was injected with Photofrin II, intravenously (2.5mg/kg body weight). The other group received no Photofrin II. Mice from both groups were irradialed for approximately 15 minutes at 100, 300, or 500 mW/cm2 with the argon (488nm/514.5 nm), dye(628nm) and gold vapor (pulsed 628 nm) laser light. A photosensitizer behaved as an added absorber. Under our experimental conditions, the presence of Photolfrin II increased surface temperature by at least 40% and the temperature rise due to 300 mW/cm2 irradiation exceeded values for hyperthermia. Light and temperature distributions with depth were estimated by a computer model. The model demonstrated the influence of wavelength on the thermal process and proved to be a valuable tool to investigate internal temperature rise. 30536 T00401030536 ^x We investigated the structural geometry of thirty-eight Korean femurs. The purpose of this study is to identify major geometrical differences between Korean femurs 3nd others that we believe belong to Caucasians so that we would be able to get insights into the femoral component design that fits Asians including Koreans. We utilized computerized tomography (CT) images of femurs extracted from cadavers. The CT images were transformed into bitmap data by using a film scanner, and then analyzed by using a commercially available software called Image v.1.0 and a Macintosh IIci computer.The resulting data were compared with already published data. The major results show that the geometry of the Korean femurs is significantly different from that of Caucasians: (1) the anteversion angle and the canal flare index are greater by the amount of approximately 8˚ and 0.5, respectively, (2) the shape of the isthmus cross section is more round, and (3) the distance between the teaser trochanter and the proximal border of the isthmus is shelter by about 15 mm. The results suggested that the femoral component suitable for Asians should be different from the currently-used components designed and manufactured mostly by European or American companies. 30537 T00401030537 ^x It is well known that nonlinear propagation characteristics of the wave in the tissue may give very useful information for the medical diagnoisis. In this paper, a new method to detect nonlinear propagation characteristics of the internal vibration in the tissue for the low frequency mechanical vibration by using bispectral analysis is proposed. In the method, low frequency vibration of f0( = 100Hz) is applied on the surface of the object, and the waveform of the internal vibration x (t) is measured from Doppler frequency modulation of silmultaneously transmitted probing ultrasonic waves. Then, the bispectra of the signal x (t) at the frequencies (f0, f0) and (f0, 2f0) are calculated to estimate the nonlinear propagation characteristics as their magnitude ratio, w here since bispectrum is free from the gaussian additive noise we can get the value with high S/N. Basic experimental system is constructed by using 3.0 MHz probing ultrasonic waves and the several experiments are carried out for some phantoms. Results show the superiority of the proposed method to the conventional method using power spectrum and also its usefulness for the tissue characterization. 30541 T00401030541 ^x This paper describes the implementation of a computerized radial pulse diagnosis by aids of a clinical expert. On this base, we composed of the radial pulse diagnosis system in korean traditional medicine. The system composed of a radial pulse wave detection system and a radial pulse diagnosis system. With a detection system, we detected Inyoung and Cheongu radial pulse wave and processed it. Then, we have got the characteristic parameters of radial pulse wave and also quantified that according to the method of Inyoung-Cheongu Comparison Radial Pulse Diagnosis. We defined the jugement standard of radial pulse diagnosis system and then we confirmed the possibility for realization of automatic radial pulse diagnosis in korean traditional medicine. 30545 T00401030545 ^x Microspheres are expected to be applied to biomedical areas such as solid-phase immunoassays, drug delivery systems, immunomagnetic cell separation. To synthesize microspheres for biomedical application, "two stage shot growth method" was developed. The uniformity ratio of synthesized microspheres was always smaller than 1.05. And the surface charge density (or the number of ionizable functional groups) of the microspheres synthesized by "two stage shot growth method" was 6~13 times higher than that of the microspheres synthesized by conventional seeded batch copolymerization. As a previous step for biomedical application, adsorption experiments of bovine albumin on microspheres were carried out under various conditions. The maximum adsorbed amount was obtained in the neighborhood of pH 4.5. Isoelectric point of bovine albumin is pH 5.0, so experimental result shows that it shifted to acid area. The adsorption isotherm was obtained, the plateau region was always reached at 2.Og/L (bulk concentration of bovine albumin).The effect of the kind and the amount of surface functional group was also examined. 30575 T00401030575 ^x A medical image workstation was developed using multimedia technique. The system based on PC-486DX was designed to acquire medical images produced by medical imaging instruments and related audio information, that is, doctors' reporting results. Input information was processed and analyzed, then the results were presented in the form of graph and animation. All the informations of the system were hierarchically related with the image as the apex. Processing and analysis algorithms were implemented so that the diagnostic accuracy could be improved. The diagnosed information can be transferred for patient diagnosis through LAN(local area network). 30592 T00401030592 ^x In the conventional infrared imaging system, complex infrared lens systems are usually used for directing collimated narrow infrared beams into the high speed 2-dimensional optic scanner. In this paper, a simple reflective infrared optic system with a 2-dimensional optic scanner is proposed for the realization of medical infrared thermography system. It has been experimentally proven that the intfrared thermography system composed of the proposed optic system has the temperature resolution of 0.1˚c under the spatial resolution of lmrad, the image matrix size of 256 X 240, and tile imaging time of 4 seconds. 30593 T00401030593 ^x In this paper, MIIS (Medical Image Information System) has been designed and implemented using INGRES RDBMS, which is based on a client/server architecture. The implemented system allows users to register and retrieve patient information, medical images and diagnostic reports. It also provides the function to display these information on workstation windows simultaneously by using the designed menu-driven graphic user interface. The medical image compression/decompression techniques are implemented and integrated into the medical image database system for the efficient data storage and the fast access through the network. 30594 T00401030594 ^x In this paper, computerized BEAM was implemented for the space domain analysis of EEG. Trans-formation from temporal summation to two-dimensional mappings is formed by 4 nearest point inter-polaton method. Methods of representation of BEAM are two. One is dot density method which classify brain electrical potential 9 levels by dot density of gray levels and the other is colour method which classify brain electrical 12 levels by red-green colours. In this BEAM, instantaneous change and average energy distribution over any arbitrary time interval of brain electrical activity could be observed and analyzed easily. In the frequency domain, the distribution of energy spectrum of a special band can easily be distinguished normality and abnormality. 30608 T00401030608 ^x Laboratory information system (LIS) is a key tool to manage laboratory data in clinical pathology. Our department has developed an information system for routine hematology using down-sized computer system. We have used an IBM 486 compatible PC with 16MB main memory, 210 MB hard disk drive, 9 RS-232C port and 24 pin dot printer. The operating system and database management system were SCO UNIX and SCO foxbase, respectively. For program development, we used Xbase language provided by SCO foxbase. The C language was used for interface purpose. To make the system use friendly, pull-down menu was used. The system connected to our hospital information system via application program interface (API), so the information related to patient and request details is automatically transmitted to our computer. Our system interfaced with fwd complete blood count analyzers(Sysmex NE-8000 and Coulter STKS) for unidirectional data tansmission from analyzer to computer. The authors suggests that this system based on down-sized computer could provide a progressive approach to total LIS based on local area network, and the implemented system could serve as a model for other hospital's LIS for routine hematology. 30609 T00401030609 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed a composite that is consisted of calcium phosphate and collagen. To use as the structural matrix of the composite, collagen was purified from human umbilical cord. The obtained collagen was treated by pepsin to remove telopeptides, and finally, the immune-free atelocollagen was produced: The cross linked atelocollagen was highly resistant to the collagenase induced collagenolysis. The cross linked collagen demonstrated an improved tensile strength. 30618 T00401030618 ^x This paper is a study on the design of adptive filter for QRS complex detection. We propose a simple adaptive algorithm to increase capability of noise cancelation in QRS complex detection with two stage adaptive filter. At the first stage, background noise is removed and at the next stage, only spectrum of QRS complex components is passed. Two adaptive filters can afford to keep track of the changes of both noise and QRS complex. Each adaptive filter consists of prediction error filter and FIR filter The impulse response of FIR filter uses coefficients of prediction error filter. The detection rates for 105 and 108 of MIT/BIH data base were 99.3% and 97.4% respectively. 30619 T00401030619 ^x To develop an artificial bone substitute that is gradually degraded and replaced by the regenerated natural bone, the authors designed and produced a composite that is consisted of calcium phosphate and collagen. Human umbilical cord origin pepsin treated type I atelocollagen was used as the structural matrix, by which sintered or non-sintered carbonate apatite was encapsulated to form an inorganic-organic composite. With cross linking atelocollagen by UV ray irradiation, the resistance to both compressive and tensile strength was increased. Collagen degradation by the collagenase induced collagenolysis was also decreased. 30620 T00401030620 ^x We have developed a monoleaflet polymer valve as an inexpensive and viable alternative, especially for short-term use in the ventricular assist device or total artificial heart. The frame and leaflet of the polymer valve were made from polyurethane, To evaluate the hemodynamic performance of the polymer valve a comparative study of flow dynamics past a polymer valve and a St. Jude Medical prosthetic valve under physiological pulsatile flow conditions in vitro was made. Comparisons between the valves were made on the transvalvular pressure drop, regurgitation volume and maximum valve opening area. The polymer valve showed smaller regurgitation volume and transvalvular pressure drop compared to the mechanical valve at higher heart rate. The results showed that the functional characteristics of the polymer valve compared favorably with those of the mechanical valve at higher heart rate. 30621 T00401030621 ^x Explosive evaporative removal process of biological tissue by absorption of a CW laser has been simulated by using gelatin and a multimode Nd:YAG laser. Because the point of maximun temperature of laser-irradiated gelatin exists below the surface due to surface cooling, evaporation at the boiling temperature is made explosively from below the surface. The important parameters of this process are the conduction loss to laser power absorption (defined as the conduction-to-laser power parameter, Nk), the convection heat transfer at the surface to conduction loss (defined as Bi), dimensionless extinction coefficient (defined as Br.), and dimensionless irradiation time (defined as Fo). Dependence of Fo on Nk and Bi has been observed by experiment, and the results have been compared with the numerical results obtained by solving a 2-dimensional conduction equation. Fo and explosion depth (from the surface to the point of maximun temperature) are increased when Nk and Bi are increased.To find out the minimum laser power for explosive evaporative removal process, steady state analysis has been also made. The limit of Nk to induce evaporative removal, which is proportional to the inverse of the laser power, has been obtained. 30622 T00401030622 ^x N1 and N2 gross neural action potentials were measured from the round window of the guinea pig cochlea at the onset of the acoustic stimuli. N1-N2 audiograms were made by means of regulating stimulant intensities in order to produce constant N1-N2 potentials as criteria for different input tone pip frequencies. The lowest threshold was measured with an input tone pip I5 dB SPL in intensity and 12 KHz in frequency when the animal was in normal physiological condition. The procedure of experimental measurements is explained in detail. This experimental approach is very useful for the investigation of the Cochlear function. Both noN1inear and active functions of the Cochlea can be monitored by N1-N2 audiograms. 30623 T00401030623 ^x In electrical impedance tomography(EIT), we use boundary current and voltage measurements toprovide the information about the cross-sectional distribution of electrical impedance or resistivity. One of the major problems in EIT has been the inaccessibility of internal voltage or current data in finding the internal impedance values. We propose a new image reconstruction method using internal current density data measured by NMR. We obtained a two-dimensional current density distribution within a phantom by processing the real and imaginary MR images from a 4.77 NMR machine. We implemented a resistivity mage reconstruction algorithm using the finite element method and sensitivity matrix. We presented computer simulation results of the mage reconstruction algorithm and furture direction of the research. 30624 T00401030624 ^x A new method of digital image analysis technique for discrimination of cancer cell was presented in this paper. The object image was the Thyroid eland cells image that was diagnosed as normal and abnormal (two types of abnormal: follicular neoplastic cell, and papillary neoplastic cell), respectively. By using the proposed region segmentation algorithm, the cells were segmented into nucleus. The 16 feature parameters were used to calculate the features of each nucleus. A9 a consequence of using dominant feature parameters method proposed in this paper, discrimination rate of 91.11% was obtained for Thyroid Gland cells. 30625 T00401030625 ^x An electrical stimulator was designed to induce locomotion for paraplegic patients caused by central nervous system injury. Optimal stimulus parameters, which can minimize muscle fatigue and can achieve effective muscle contraction were determined in slow and fast muscles in Sprague-Dawley rats. Stimulus patterns of our stimulator were designed to simulate electromyographic activity monitored during locomotion of normal subjects. Muscle types of the lower extremity were classified according to their mechanical property of contraction, which are slow muscle (msoleus m.) and fast muscle (medial gastrocneminus m., rectus femoris m., vastus lateralis m.). Optimal parameters of electrical stimulation for slow muscles were 20 Hz, 0.2 ms square pulse. For fast muscle, 40 Hz, 0.3 ms square pulse was optimal to produce repeated contraction. Higher stimulus intensity was required when synergistic muscles were stimulated simultaneously than when they were stimulated individually. Electrical stimulation for each muscle was designed to generate bipedal locomotion, so that individual muscles alternate contraction and relaxation to simulate stance and swing phases. Portable electrical stimulator with 16 channels built in microprocessor was constructed and applied to paraplegic patients due to lumbar cord injury. The electrical stimulator restored partially gait function in paraplegic patients. 30626 T00401030626 ^x Two-Dimensional modelling of the Cochlear biomechanics is presented in this paper. The Laplace partial differential equation which represents the fluid mechanics of the Cochlea has been transformed into two-dimensional electrical transmission line. The procedure of this transformation is explained in detail. The comparison between one and two dimensional models is also presented. This electrical modelling of the basilar membrane (BM) is clearly useful for the next approach to the further. Development of active elements which are essential in the producing of the sharp tuning of the BM. This paper shows that two-dimension model is qualitatively better than one-dimensional model both in amplitude and phase responses of the BM displacement. The present model is only for frequency response. However because the model is electrical, the two-dimensional transmission line model can be extended to time response without any difficult. 30627 T00401030627 ^x A method has been proposed for the fully automatic detection of left ventricular endocardial boundary in 2D short axis echocardiogram using geometric model. The procedure has the following three distinct stages. First, the initial center is estimated by the initial center estimation algorithm which is applied to decimated image. Second, the center estimation algorithm is applied to original image and then best-fit elliptic model estimation is processed. Third, best-fit boundary is detected by the cost function which is based on the best-fit elliptic model. The proposed method shows effective result without manual intervention by a human operator. 30628 T00401030628 ^x The intelligent trajectory control method that controls moving direction and average velocity for a prosthetic arm is proposed by pattern recognition and force estimations using EMG signals. Also, we propose the real time trajectory planning method which generates continuous accelleration paths using 3 stage linear filters to minimize the impact to human body induced by arm motions and to reduce the muscle fatigue. We use combination of MLP and fuzzy filter for pattern recognition to estimate the direction of a muscle and Hogan's method for the force estimation. EMG signals are acquired by using a amputation simulator and 2 dimensional joystick motion. The simulation results of proposed prosthetic arm control system using the EMf signals show that the arm is effectively followed the desired trajectory depended on estimated force and direction of muscle movements. 30638 T00401030638 ^x A new neural network architecture for the recognition of patterns from images is proposed, which is partially based on the results of physiological studies. The proposed network is composed of multi-layers and the nerve cells in each layer are connected by spatial filters which approximate receptive fields in optic nerve fields. In the proposed method, patterns recognition for complicated images is carried out using global features as well as local features such as lines and end-points. A new generating method of matched filers representing global features is proposed in this network. 30659 T00401030659 ^x An implementation scheme of the magnetic nerve stimulator using a switching mode power supply is proposed. By using a switching mode power supply rather than a conventional linear power supply for charging high voltage capacitors, the weight and size of the magnetic nerve stimulator can be considerably reduced. Maximum output voltage of the developed magnetic nerve stimulator using the switching mode power supply is 3, 000 volts and switching time is about 100 msec. Experimental results or human nerve stimulations using the developed stimulator are presented. 30768 T00401030768 ^x In this paper, we describe the design methodology and specifications of the developed module-based bedside monitors for patient monitoring. The bedside monitor consists of a main unit and module cases with various parameter modules. The main unit includes a 12.1" TFT color LCD, a main CPU board, and peripherals such as a module controller, Ethernet LAN card, video card, rotate/push button controller, etc. The main unit can connect at maximum three module cases each of which can accommodate up to 7 parameter modules. They include the modules for electrocardiograph, respiration, invasive blood pressure, noninvasive blood pressure, temperature, and SpO2 with Plethysmograph.SpO2 with Plethysmograph.

• 한국작물학회지
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• 제14권
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• pp.1-40
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• 1973

수도의 다수확을 위하여 근래 다비재배의 경향이 높아가고 있는 반면에 등숙률의 저하가 증수저해요인으로 크게 문제되고 있다. 특히 최근 육성된 통일품종은 이점이 더 심각한 바 있어 등숙의 향상책을 모색하고저 1970년부터 1972년까지 3개년간에 걸쳐 수원 작물시험장포장과 인공기상실에서 주로 진흥과 통일을 공시하여 증숙에 관한 일련의 실험을 시행한 바 그 결과를 요약하면 다음과 같다. 1. 통일의 곡립은 발아등 종래품종에 비하여 세장하고 곡립의 폭 및 두께가 작으며 비중과의 상관관계는 진흥에 있어서는 곡립의 무게, 두께, 폭 및 길이의 순으로 낮으나 통일은 무게, 폭, 두께 및 길이의 순으로 낮았다. 2. 비중별 립수분포에 있어서 종래의 Japonica도는 비중 1.18을 정점으로 대부분 1.12이상에 분포하고 있으나 통일계통에서는 1.12이하의 곡립도 상당수 분포하였고 진흥이 비중 1.06이하에서 정현비율이 급감하고 있으나 통일에 있어서는 비중 1.20에서 0.96까지의 곡립의 정현비율이 별로 차이가 없으므로 1.06을 등숙립의 선별기준으로 삼는 것은 불합리한 것으로 인정된다. 3. 출수후의 등숙속도는 품종간차이가 현저하며 대체로 한랭지 재배품종일수록 느렸으며 통일은 원래 등숙이 빠른 편이나 등숙후기에는 기온의 저하로 인하여 그 속도가 떨어졌다. 4. 지발분얼 또는 약세분얼은 수당영화수도 적을 뿐 아니라 등숙률도 낮은데 통일은 지발분얼이 많고 이들은 저온하에서 출수하여 수전일수가 연장되고 등숙률이 떨어졌다. 5. 통일의 엽신은 짧고 넓으며 엽신전개력은 다비조건에서는 진흥만큼 크고 또 엽의 경사각도는 적어 수광태세가 양호하였다. 통일 엽신의 단위동화능력은 고온하에서는 비교적 크나 저온하에서는 떨어졌다. 6. 통일은 단간이며 하위절간이 짧고 굵어서 도복저항성이 크고 출수전 저장탄수화물이 많았으며 인산, 규산, 석회, 망간 및 마그네슘 등의 체내함유율이 높았다. 7. 통일은 비교적 많은 영화수를 가지고 있고 진흥이 영화수와 등숙률간에 유의적인 역상관이 있음에 비하여 통일은 고온다조하에서는 영화수가 많아도 등숙률은 떨어지지 않고 영화수증가에 비례하여 수량이 많아졌다. 8. 진흥에 비하여 통일의 뿌리는 천근성이며 고온하에서는 그 활력이 컸으나 저온시에는 엽신이 황갈색으로 변하고 그 변색정도에 비례해서 뿌리의 활력도 떨어졌다. 9. 통일은 수광태세가 좋고 동화일호흡균형상 유리한 생산구조를 갖어 진흥보다 이상적인 모형이었다. 10. 수원지방의 수도보통기재배에 있어서 수량생산기간의 일사량은 비교적 풍부한 편이나 8월25일이후에 출수할 때에는 평균기온이 22$^{\circ}C$이하로 빠르게 하강하므로서 기온이 보다 등숙의 제한요인으로 인정된다. 11. 진흥이 저온하에서도 등숙율이 비교적 높은데 통일의 등숙적온은 $25^{\circ}C$이상이며 21$^{\circ}C$이하에서는 완전등숙이 거의 불가능하였다. 12. 진흥은 감광성이 비교적 크고 감온성은 중정도인데 비하여 통일은 감광성은 작으나 기본영양생장성과 저온하의 출수지연도가 컸었다. 13. 진흥은 질소의 후기중점시비에 의하여 등숙율이 향상되고 증수되었으나 통일에 있어서는 기비중점으로 질소를 시용하여 영화를 많이 확보하여도 등숙율저하가 적고 오히려 증수되였다. 14. 진흥은 만식적응성이 비교적 크나 통일은 조식효과가 크고 만식하면 출수가 지연되고 등숙온도가 낮아져서 등숙율과 수량이 떨어졌다. 15. 통일은 내비성과 밀식적응성이 커서 다비밀식조건에서 그 다수성을 발휘하는 특성을 가졌으며 주수 및 묘수증가에 의하여 수전일수가 단축되고 등숙률이 향상되었다. 16. 재식거리를 좁히고 어느 정도 주당묘수를 늘리면 강세분얼비율이 높아졌다. 17. 인산은 저온시에는 등숙율을 상당히 향상시켰다. 이상을 요약해보면 종래품종들의 등숙향상을 꾀하자면 8월20일이전에 출수시켜야 하며 10a당 질소 7.5kg 이상의 과다한 기비를 억제하고 후기중점으로 시비하여 동화효율을 높여야할 것이다. 한편 통일은 곡립이 세장하고 식물체가 작고 뭉툭한 등 종래품종과 판이한 외부형태와 더불어 그 생리생태적 특성도 상이한 점이 많으므로 등숙립선별, 도정 및 재배법상에도 종전품종과 다른 고려가 있어야 할 것이다. 즉 등숙립 선별기준에 대하여는 통일의 비중별 입수분포 및 정현비율로 보아 종래의 등숙립 선별기준인 비중 1.06 보다는 0.96을 적용하는 것이 합리적이고 도정상으로는 통일의 곡립이 세장하고 폭 및 두께가 작다는 것을 고려하여야 한다. 재배법에 있어서 통일의 등숙률이 낮은 원인이 주로 약세분얼이 많고 저온하에서는 출수가 지연되고 뿌리와 엽신의 기능이 저하되며 불임이 증가되는 것으로 판명되었고 그 외에 통일은 다비밀식적응성이 크므로 등숙향상과 수량 증대를 위해서는 적극적인 방법으로서 우선 견실하고 큰 묘를 가능한 한 조식하고 다비밀식상태로 재배하되 충분한 기비를 시용하고 묘수를 3본 내외로 심고 인산 및 규산등을 충분히 시용하여야 할 것이다.