• Journal of architectural history
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• v.18 no.5
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• pp.25-39
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• 2009

The examples of developing a building site after the Woongjin period are mainly found in temple sites, tile-roofed building sites of unidentified features, and palace remains including the pavilion site with the river in the front(임류각지) inside the Castle of Gongsan, Gongjoo. In case of the Hanseong period, a glimpase of the features has gained in Poongnab mud castle and Mongchon mud castle, but the excavated relics are not yet enough to make some date out of them. After the Woongjin period of Baejae, the earth-ramming development method was used mostly to construct a building site, which is divided into horizontal and slant raising of the ground level. Both are used simultaneously, but there are the significant differences in the way of raising the ground level between them. Particularly, in case of the Wanggoong-ri relics in Iksan, the ground level was raised in a narrow line slantly, which is differentiated from other slant raising of the ground level, and its time of construction also is after that of others. In addition, the board-building development method used for narrow space is usually found in the remains since the seventh century. However, there are not enough the relics of Baekjae to reveal the whole aspect of building site development. It should be studied later through the subsequent excavation and research.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.39 no.1
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• pp.17-24
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• 2016

Many organizations have transformed their business in order to survive and compete in the future. They generate projects by creating a vision, using strategies and objectives with funds aligning strategies and make efforts to complete them successfully because project success leads to business success. All projects have triple constraints such as scope, time, and cost to be completed. Project cost performance is a key factor to achieve project goals and which is mostly related with risks among various cost drivers. Projects require a cost estimation method to complete them within their budget and on time. An accurate budget cannot be estimated due to the uncertainties and risks. Thus some additional money should be funded in addition to the base budget as a contingency reserve for identified risks and a management reserve for unidentified risks. While research on contingency reserve for identified risks included in project budget baseline have been presented, research on management reserve for unidentified risks included in total project budget is still scarce. The lack of research on estimation method and role of the management reserve have made project managers little confidence to estimate project budget accurately with reasonable basis. This study proposes a practical model to estimate budgets including contingency and management reserves for not only project cost management but also to keep the balance of organization's total funds to maximize return on investments for project portfolio management. The advantages of the proposed model are demonstrated by its application to construction projects in Korea and the processes to apply this model for verification are also provided.

• Genomics & Informatics
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• v.20 no.1
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• pp.2.1-2.11
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• 2022

The method of single-cell RNA sequencing has been rapidly developed, and numerous experiments have been conducted over the past decade. Their results allow us to recognize various subpopulations and rare cell states in tissues, tumors, and immune systems that are previously unidentified, and guide us to understand fundamental biological processes that determine cell identity based on single-cell gene expression profiles. However, it is still challenging to understand the principle of comprehensive gene regulation that determines the cell fate only with transcriptome, a consequential output of the gene expression program. To elucidate the mechanisms related to the origin and maintenance of comprehensive single-cell transcriptome, we require a corresponding single-cell epigenome, which is a differentiated information of each cell with an identical genome. This review deals with the current development of single-cell epigenomic library construction methods, including multi-omics tools with crucial factors and additional requirements in the future focusing on DNA methylation, chromatin accessibility, and histone post-translational modifications. The study of cellular differentiation and the disease occurrence at a single-cell level has taken the first step with single-cell transcriptome and is now taking the next step with single-cell epigenome.

• Structural Engineering and Mechanics
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• v.81 no.3
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• pp.293-303
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• 2022

As infrastructure ages and traffic load increases, serious public concerns have arisen for the well-being of bridges. The current health monitoring practice focuses on large-scale bridges rather than short span bridges. However, it is critical that more attention should be given to these behind-the-scene bridges. The relevant information about the construction methods and as-built properties are most likely missing. Additionally, since the condition of a bridge has unavoidably changed during service, due to weathering and deterioration, the material properties and boundary conditions would also have changed since its construction. Therefore, it is not appropriate to continue using the design values of the bridge parameters when undertaking any analysis to evaluate bridge performance. It is imperative to update the model, using finite element (FE) analysis to reflect the current structural condition. In this study, a FE model is established to simulate a concrete culvert bridge in New South Wales, Australia. That model, however, contains a number of parameter uncertainties that would compromise the accuracy of analytical results. The model is therefore updated with a neural network (NN) optimisation algorithm incorporating Monte Carlo (MC) simulation to minimise the uncertainties in parameters. The modal frequency and strain responses produced by the updated FE model are compared with the frequency and strain values on-site measured by sensors. The outcome indicates that the NN model updating incorporating MC simulation is a feasible and robust optimisation method for updating numerical models so as to minimise the difference between numerical models and their real-world counterparts.

• Nuclear Engineering and Technology
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• v.40 no.7
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• pp.561-570
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• 2008

When reactivity insertion such as refueling occurs in CANDU reactors, the power and the water levels are tilted in the upper outer zone of the LZCS (Liquid Zone Control System) and fluctuate unstably for a certain period of time (1-5 days). The instability described above is observed in most CANDU reactors in service around the world, but its root cause is unidentified and no solutions to this problem have been established. Therefore, this study attempted to prove experimentally and analytically that the root cause lies in the hold-up of light water on the top of the TSP (Tube Support Plate) due to the mismatch between net volumetric flow rate of light water and helium crossing the narrowed porous TSP installed within the LZCS compartment. Our method was to perform a hydrodynamic simulation of in/outflow of light water and helium. Two solutions for the aforementioned instability of LZCS are suggested. One is to regulate the compartment for both inflowing helium gas and outflowing light water; the other is to enlarge the flow paths of helium and light water within TSP. The former may be applicable to nuclear reactors in service and the latter to those planned for construction.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.10
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• pp.851-856
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• 2005

The DNA and protein data of diverse species have been daily discovered and deposited in the public archives according to each established format. Database systems in the public archives provide not only an easy-to-use, flexible interface to the public, but also in silico analysis tools of unidentified sequence data. Of such in silico analysis tools, multiple sequence alignment [1] methods relying on pairwise alignment and Smith-Waterman algorithm [2] enable us to identify unknown DNA, protein sequences or phylogenetic relation among several species. However, in the existing multiple alignment method as the number of sequences increases, the runtime increases exponentially. In order to remedy this problem, we adopted a parallel processing suffix tree algorithm that is able to search for common subsequences at one time without pairwise alignment. Also, the cross-matching subsequences triggering inexact-matching among the searched common subsequences might be produced. So, the cross-matching masking process was suggested in this paper. To identify the function of the clusters generated by suffix tree clustering, BLAST was combined with a clustering tool. Our clustering and annotating tool is summarized as the following steps: (1) construction of suffix tree; (2) masking of cross-matching pairs; (3) clustering of gene sequences and (4) annotating gene clusters by BLAST search. The system was successfully evaluated with 22 gene sequences in the pyrubate pathway of bacteria, clustering 7 clusters and finding out representative common subsequences of each cluster

• Journal of the Korean Wood Science and Technology
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• v.49 no.2
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• pp.122-133
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• 2021

The radon gas from nature mainly considers a cause of radon problems, and it is closely affect human life cycle. Korean yellow residual soil, Hwangtoh, widely used as a building material, is considered to be one of major sources of indoor radon. However, there have, as yet, been no studies about radon from Hwangtoh in mass market brands. Here, we investigated the indoor radon concentrations and exhalation rates in four Hwangtohs from different brand names and regional features. The Closed Chamber Method (CCM) conducted by a Continuous Radon Monitor (CRM) has been used for the rates of radon exhalation. Based on equations of previous references, the indoor radon concentrations were deducted. As a result, the radon surface exhalation rates resulted in the 1.4208 to 3.0293 Bq·㎡·h-1 range. Significant differences were found among Hwangtohs according to production regions. Materials with higher radon concentration required a longer time to reach a quasi-steady state in a given environment, in other words, the number of half-life cycles increased from a set starting point. The experimentally identified Hwangtohs demonstrated its safety for construction purposes. There exists, so far, a possibility to exert influence radon emanation due to unidentified factors. Therefore, it is necessary to corroborate with more research by increasing the number of Hwangtohs, considering the other references reported high radon exhalation rates. In addition, it is highly recommended that the radon exhalation rates should be measured for all building materials for preventing human health before the material usage.