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The Changes of Cerebral Metabolic and Hemodynamic Parameters, Brain Histology, and Serum Levels of Neuron-Specific Enolase During Retrograde Cerebral Perfusion Under Pofound Hypothermic total Circulatory Arrest in Pigs (돼지에서 초저체온 순환정지 하의 역행성 뇌관류시 뇌대사, 혈류역학 지표, 뇌조직 소견 및 혈청 내 neuron-specific enolase의 변화)

  • Kim, Kyung-Hwan;Ahn, Hyuk
    • Journal of Chest Surgery
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    • v.33 no.6
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    • pp.445-468
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    • 2000
  • Background: Retrograde cerebral perfusion(RCP) is currently used for brain protection during aorta surgery, however, for the safety of it, various data published so far are insufficient. We performed RCP using pig and investiaged various parameters of cerebral metabolism and brain injury after RCP under deep hypothermia. Material and Method: We used two experimental groups: in group I(7 pigs, 20 kg), we performed RCP for 120 minutes and in group II (5 pigs, 20 kg), we did it for 90 minutes. Nasopharyngeal temperature, jugular venous oxygen saturation, electroencephalogram were continuously monitored, and we checked the parameters of cerebral metabolism, histological changes and serum levels of neuron-specific enolose(NSE) and lactic dehydrogenase(LDH). Central venous pressure during RCP was mainained in the range of 25 to 30 mmHg. Result: Perfusion flow rates(ml/min) during RCP were 130$\pm$57.7(30 minutes), 108.6$\pm$55.2(60 minutes), 107.1$\pm$58.8(90 minutes), 98.6$\pm$58.7(120 minutes) in group I and 72$\pm$11.0(30 minutes), 72$\pm$11.0(60 minutes), 74$\pm$11.4(90 minutes) in group II. The ratios of drain flow to perfusion flow were 0.18(30 minutes), 0.19(60 minutes), 0.17(90 minutes), 0.16(120 minutes) in group I and 0.21, 0.20, 0.17 in group II. Oxygen consumptions(ml/min) during RCP were 1.80$\pm$1.37(30 minutes), 1.72$\pm$1.23(60 minutes), 1.38$\pm$0.82(90 minutes), 1.18$\pm$0.67(120 minutes) in group I and 1.56$\pm$0.28(30 minutes), 1.25$\pm$0.28(60 minutes), 1.13$\pm$0.26(90 minutes). We could observe an decreasing tendency of oxygen consumption after 90 minutes of RCP in group I. Cerebrovascular resistance(dynes.sec.cm-5) during RCP in group I incrased from 71370.9$\pm$369145.5 to 83920.9$\pm$49949.0 after the time frame of 90 minutes(p<0.05). Lactate(mg/min) appeared after 30 minutes of RCP and the levels were 0.15$\pm$0.07(30 minutes), 0.18$\pm$0.10(60 minutes), 0.19$\pm$0.19(90 minutes), 0.18$\pm$0.10(120 minutes) in group I and 0.13$\pm$0.09(30 minutes), 0.19$\pm$0.03(60 minutes), 0.29$\pm$0.11(90 minutes) in group II. Glucose utilization, exudation of carbon dioxide, differences of cerebral tissue acidosis between perfusion blood and drain blood were maintained constantly during RCP. Oxygen saturation levels(%) in drain blood during RCP were 22.9$\pm$4.4(30 minutes), 19.2$\pm$4.5(60 minutes), 17.7$\pm$2.8(90 minutes), 14.9$\pm$2.8(120 minutes) in group I and 21.3$\pm$8.6(30 minutes), 20.8$\pm$17.6(60 minutes), 21.1$\pm$12.1(90 minutes) in group II. There were no significant changes in cerebral metabolic parameters between two groups. Differences in serum levels of NSE and LDH between perfusion blood and drain blood during RCP showed no statistical significance. Serum levels of NSE and LDH after resuming of cardipulmonary bypass decreased to the level before RCP. Brain water contents were 0.73$\pm$0.03 in group I and 0.69$\pm$0.06 in group II and were higher than those of the controls(p<0.05). The light microscopic findings of cerebral neocortex, basal ganglia, hippocampus(CA1 region) and cerebellum showed no evidence of cerebral injury in two groups and there were no different electron microscopy in both groups(neocortex, basal ganglia and hippocampus), but they were thought to be reversible findings. Conclusion: Although we did not proceed this study after survival of pigs, we could perform the RCP successfully for 120 minutes with minimal cerebral metabolism and no evidence of irreversible brain damage. The results of NSE and LDH during and after RCP should be reevaluated with survival data.

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Vegetation classification based on remote sensing data for river management (하천 관리를 위한 원격탐사 자료 기반 식생 분류 기법)

  • Lee, Chanjoo;Rogers, Christine;Geerling, Gertjan;Pennin, Ellis
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.6-7
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    • 2021
  • Vegetation development in rivers is one of the important issues not only in academic fields such as geomorphology, ecology, hydraulics, etc., but also in river management practices. The problem of river vegetation is directly connected to the harmony of conflicting values of flood management and ecosystem conservation. In Korea, since the 2000s, the issue of river vegetation and land formation has been continuously raised under various conditions, such as the regulating rivers downstream of the dams, the small eutrophicated tributary rivers, and the floodplain sites for the four major river projects. In this background, this study proposes a method for classifying the distribution of vegetation in rivers based on remote sensing data, and presents the results of applying this to the Naeseong Stream. The Naeseong Stream is a representative example of the river landscape that has changed due to vegetation development from 2014 to the latest. The remote sensing data used in the study are images of Sentinel 1 and 2 satellites, which is operated by the European Aerospace Administration (ESA), and provided by Google Earth Engine. For the ground truth, manually classified dataset on the surface of the Naeseong Stream in 2016 were used, where the area is divided into eight types including water, sand and herbaceous and woody vegetation. The classification method used a random forest classification technique, one of the machine learning algorithms. 1,000 samples were extracted from 10 pre-selected polygon regions, each half of them were used as training and verification data. The accuracy based on the verification data was found to be 82~85%. The model established through training was also applied to images from 2016 to 2020, and the process of changes in vegetation zones according to the year was presented. The technical limitations and improvement measures of this paper were considered. By providing quantitative information of the vegetation distribution, this technique is expected to be useful in practical management of vegetation such as thinning and rejuvenation of river vegetation as well as technical fields such as flood level calculation and flow-vegetation coupled modeling in rivers.

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A study on the engineering optimization for the commercial scale coal gasification plant (상용급 석탄가스화플랜트 최적설계에 관한 연구)

  • Kim, Byeong-Hyeon;Min, Jong-Sun;Kim, Jae-Hwan
    • 한국신재생에너지학회:학술대회논문집
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    • 2010.11a
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    • pp.131.1-131.1
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    • 2010
  • This study was conducted for engineering optimization for the gasification process which is the key factor for success of Taean IGCC gasification plant which has been driven forward under the government support in order to expand to supply new and renewable energy and diminish the burden of the responsibility for the reduction of the green house gas emission. The gasification process consists of coal milling and drying, pressurization and feeding, gasification, quenching and HP syngas cooling, slag removal system, dry flyash removal system, wet scrubbing system, and primary water treatment system. The configuration optimization is essential for the high efficiency and the cost saving. For this purpose, it was designed to have syngas cooler to recover the sensible heat as much as possible from the hot syngas produced from the gasifier which is the dry-feeding and entrained bed slagging type and also applied with the oxygen combustion and the first stage cylindrical upward gas flow. The pressure condition inside of the gasifier is around 40~45Mpg and the temperature condition is up to $1500{\sim}1700^{\circ}C$. It was designed for about 70% out of fly ash to be drained out throughout the quenching water in the bottom part of the gasifier as a type of molten slag flowing down on the membrane wall and finally become a byproduct over the slag removal system. The flyash removal system to capture solid particulates is applied with HPHT ceramic candle filter to stand up against the high pressure and temperature. When it comes to the residual tiny particles after the flyash removal system, wet scurbbing system is applied to finally clean up the solids. The washed-up syngas through the wet scrubber will keep around $130{\sim}135^{\circ}C$, 40~42Mpg and 250 ppmv of hydrochloric acid(HCl) and hydrofluoric acid(HF) at maximum and it is turned over to the gas treatment system for removing toxic gases out of the syngas to comply with the conditions requested from the gas turbine. The result of this study will be utilized to the detailed engineering, procurement and manufacturing of equipments, and construction for the Taean IGCC plant and furthermore it is the baseline technology applicable for the poly-generation such as coal gasification(SNG) and liquefaction(CTL) to reinforce national energy security and create new business models.

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Structural Stability, Weathering and Conservation Method of Granite Standing Sculptured Buddha at Hwangsang-dong, Kumi (구미 황상동 마애여래입상의 구조적 안정성, 풍화 및 보존방안)

  • Lee, Chan Hee;Choi, Suck Won;Suh, Mancheol;Chae, Sang Jeong
    • Journal of Conservation Science
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    • v.9 no.1
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    • pp.21-32
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    • 2000
  • Rock composition of the Hwangsang-dong Granite Standing Sculptured Buddha (Treasure No. 1122) in the Kumi City is biotite-hornblende granodiorite which consists of about 30 pieces of individual rock blocks of same compositions. However, the cap rocks is pebble-bearing coarse sandstone. Rock blocks of the Standing Buddha and surrounding out crops occur well developed several joint systems of $N25^{\circ}$ to $45^{\circ}W$ strike and nearly vertical (70 to $85^{\circ}SE$) dipping. Rock blocks of the Standing Buddha showed vertical, horizontal and oblique joints, and those blocks are well supported by individual blocks. However, the junction part of the blocks are under dangerous situation due 10 seriously mechanical and chemical weathering. Host rock of the Standing Buddha belongs to the HW grade, therefore mostly rock-forming minerals of the granodiorite Standing Buddha altered with clay and iron hydroxide minerals by mineralogical and chemical weathering. Near surface of the Standing Buddha show spore and mycelium of green algaes, and a joint plane alive with weeds. We suggest that if structural stability for the Standing Buddha remove essentially a unstable rock blocks from the main body, and the main body necessitate supporting by rock bolting method because of repeated unstability and minimizing stress to the rock blocks. For the opened joint planes, fractured surface and alive weeds will attempt to fill in a petro-epoxy, petro-filler and biochemical treatments for the algaes, and ground water curtain and wall seems to be necessary for water flow and diminishing humidity of the Standing Buddha.

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Mass Reduction and Physicochemical Properties of the Produced Compost during Composting Domestic Food Wastes in a Small Composter (소형 퇴비화용기에서 가정 음식물쓰레기의 퇴비화 과정 중 감량화 및 생산 퇴비의 물리화학적 특성)

  • Park, Ju-Won;Seo, Jeoung-Yoon
    • Korean Journal of Environmental Agriculture
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    • v.20 no.4
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    • pp.238-243
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    • 2001
  • Mass reduction and physicochemical properties of the produced compost were investigated during composting domestic food wastes without additive. A small composter used in this study had the height of 15 cm from the center of bottom half circle (diameter 24 cm) up to under the lid, the side length of 50 cm and the horizontal lid angle of $50^{\circ}$ and was operated at the heating unit temperature of $85^{\circ}$. It was mixed by the rotating arm for two minutes in every half hour while supplied with air flow at 3 L/min for 10 minutes in every half hour. This condition was found in a preliminary experiment as optimal for keeping the water content of composting material in the optimal range without adding any bulking materials. The domestic food wastes were added into the composter at the rate of 1 kg/day without additives during composting. The results were as follows; during the composting process, water content maintained in the range of $51.0{\sim}53.5%$. Hemicellulose and lignin contents did not show any tendency, but cellulose content decreased. During the composting process, $NH_3-N$ and $NO_2-N$ were not detected due to nitrification. The contents of inorganic compounds did not increase during the composting process. They were in the range of $1.32{\sim}1.71%\;P_2O_5$, $1.29{\sim}1.48%\;CaO$, $0.41{\sim}0.49%\;MgO$, and $0.38{\sim}0.74%\;K_2O$. For 20 days, weight reduction rate was 67.5% in wet basis, and decomposition rate was 48% in dry basis. Concentration of heavy metals (Cu, Cr, Cd, Pb, Zn, Hg, As) was less than the limiting value of the compost. Maturity of the produced compost was 3 grade through reaching maximum temperature of $46{\sim}48^{\circ}C$.

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Numerical Analysis of the Change in Groundwater System with Tunnel Excavation in Discontinuous Rock Mass (불연속 암반에서의 터널굴착에 따른 지하수체계 변화에 대한 수치해석적 연구)

  • Park, Jung-Wook;Son, Bong-Ki;Lee, Chung-In;Song, Jae-Joon
    • Tunnel and Underground Space
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    • v.18 no.1
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    • pp.44-57
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    • 2008
  • In this study, a 2D finite-element analysis, using the SEEP/W program, was carried out to estimate the amount of groundwater flawing into a tunnel, as well as the groundwater tables around wetland areas during and after a tunnel excavation through rock mass. Four sites along the Wonhyo-tunnel in Cheonseong Mountain (Gyeongnam, Korea) were analysed, where the model damain of the tunnel included both wetland and fault zone. The anisotropy of the hydraulic conductivities of the rock mass was calculated using the DFN model, and then used as an input parameter for the cantinuum model. Parametric study on the influencing factors was perofrmed to minimize uncertainties in the hydraulic properties. Moreover, the volumetric water content and hydraulic conductivity functions were applied ta the model to reflect the ability of a medium ta store and transport water under both saturated and unsaturated conditions. The conductivity of fault zone was assumed ta be $10^{-5}m/sec\;or\;10^{-6}m/sec$ and the conductivity of grouting zone was assumed as 1/10, 1/50 or 1/100 of the conductivity of rock mass. Totally $6{\sim}8$ cases of transient flow simulation were peformed at each site. The hydraulic conductivities of fault zone showed a significant influence on groundwater inflow when the fault zone crossed the tunnel. Also, groundwater table around wetland maintained in case that the hydraulic conductivity of grouting zone was reduced ta be less than 1/50 of the hydraulic conductivity of rock mass.

An Experimental Study on the Distributions of Residual Head and Discharge Rate along Collector Well Laterals of a Model Riverbed Filtration (하상여과의 집수관 모형에서 잔류수두와 유입율 분포에 관한 실험연구)

  • Ahn, Kyu-Hong;Moon, Hyung-Joon;Kim, Kyung-Soo;Kim, Seung-Hyun
    • Journal of Korean Society of Environmental Engineers
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    • v.27 no.12
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    • pp.1305-1310
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    • 2005
  • As a way to the optimum design of the collector well lateral in riverbed filtration, experiments were performed using sand tanks which were connected to form a model lateral system. Measured were the residual hydraulic heads along the laterals, the discharge rates at each sand tank and the production rates at the collector well while the model laterals were operated with various scenarios of changing parameters including water level of the collector well, the lateral diameter and length, and the hydraulic conductivity of the sand. Results showed that riverbed filtration could be more efficient when the resistance in the lateral was weak compared with the resistance in the sand, which was indicated by the more flattened distribution of the residual hydraulic heads along the lateral. Results also showed that the discharge rate increased exponentially with the approach to the collector well, and that the exponent increased as the lateral diameter decreased and/or the hydraulic conductivity of the sand increased. It was also seen that the well production increased with the increase in the lateral length and diameter although the marginal productivity decreased. It could be concluded that the axial flow velocity in the lateral was an important factor governing the efficiency of a lateral in riverbed filtration and that the maximum entrance velocity to the collector well, over which the efficiency decreased drastically, was about 1 m/sec under the conditions of this study.

Travel Times of Radionuclides Released from Hypothetical Multiple Source Positions in the KURT Site (KURT 환경 자료를 이용한 가상의 다중 발생원에서의 누출 핵종의 이동 시간 평가)

  • Ko, Nak-Youl;Jeong, Jongtae;Kim, Kyung Su;Hwang, Youngtaek
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.11 no.4
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    • pp.281-291
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    • 2013
  • A hypothetical repository was assumed to be located at the KURT (KAERI Underground Research Tunnel) site, and the travel times of radionuclides released from three source positions were calculated. The groundwater flow around the KURT site was simulated and the groundwater pathways from the hypothetical source positions to the shallow groundwater were identified. Of the pathways, three pathways were selected because they had highly water-conductive features. The transport travel times of the radionuclides were calculated by a TDRW (Time-Domain Random Walk) method. Diffusion and sorption mechanisms in a host rock matrix as well as advection-dispersion mechanisms under the KURT field condition were considered. To reflect the radioactive decay, four decay chains with the radionuclides included in the high-level radioactive wastes were selected. From the simulation results, the half-life and distribution coefficient in the rock matrix, as well as multiple pathways, had an influence on the mass flux of the radionuclides. For enhancing the reliability of safety assessment, this reveals that identifying the history of the radionuclides contained in the high-level wastes and investigating the sorption processes between the radionuclides and the rock matrix in the field condition are preferentially necessary.

Ozone-Enhanced Remediation of Diesel-Contaminated Soil (II): A Column Study (Ozone에 의한 유류오염토양 복원 연구 (II) : 토양 컬럼상에서의 오존 산화)

  • Choi, Heechul;Heechul;Lim, Hyung-Nam;Kim, Kwang-Soo
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.10
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    • pp.1825-1832
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    • 2000
  • Column experiments were conducted by using soil columns, to investigate feasibility and efficiency of in-situ ozone enhanced remediation for diesel-contaminated soil. The injection of gaseous ozone into soil column revealed the enhanced decomposition of ozone due to the catalytic reaction between ozone and metal (e.g., Fe, Mn etc.) oxides as evidenced by as much as 25 times shorter half-life of ozone in a sand packed column than in a glass beads packed column. Substantial retardation in the transport of and the consumption of ozone were observed in the diesel contaminated field soil and sand packed columns. After 16 hrs ozonation, 80% of the initial mass of diesel (as diesel range organic) concentration of $800{\pm}50mg/kg$, was removed under the conditions of the flow rate of 50mL/min and $6mg-O_3/min$. Whereas, less than 30% of diesel was removed in the case of air injection. Analysis of the residual TPH(total petroleum hydrocarbon) and selected 8 aliphatics of diesel compounds in the inlet and the outlet of the column confirmed that diesel nonselectively reacted with ozone and then shifted to lower carbon numbered molecules. Water content also was found to be an important parameter in employing ozone to the hydrocarbon-contaminated soil.

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Statistical significance test of polynomial regression equation for Huff's quartile method of design rainfall (설계강우량의 Huff 4분위 방법 다항회귀식에 대한 유의성 검정)

  • Park, Jinhee;Lee, Jaejoon;Lee, Sungho
    • Journal of Korea Water Resources Association
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    • v.51 no.3
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    • pp.263-272
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    • 2018
  • For the design of hydraulic structures, the design flood discharge corresponding to a specific frequency is generally used by using the design storm calculated according to the rainfall-runoff relationship. In the past, empirical equations such as rational equations were used to calculate the peak flow rate. However, as the duration of rainfall is prolonged, the outflow patterns are different from the actual events, so the accuracy of the temporal distribution of the probability rainfall becomes important. In the present work, Huff's quartile method is used for the temporal distribution of rainfall, and the third quartile is generally used. The regression equation for Huff's quadratic curve applies a sixth order polynomial equation because of its high accuracy throughout the duration of rainfall. However, in statistical modeling, the regression equation needs to be concise in accordance with the principle of simplicity, and it is necessary to determine the regression coefficient based on the statistical significance level. Therefore, in this study, the statistical significance test for regression equation for temporal distribution of the Huff's quartile method, which is used as the temporal distribution method of design rainfall, is conducted for 69 rainfall observation stations under the jurisdiction of the Korea Meteorological Administration. It is statistically significant that the regression equation of the Huff's quartile method can be considered only up to the 4th order polynomial equation, as the regression coefficient is significant in most of the 69 rainfall observation stations.