• 한국통신학회논문지
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• 제38A권5호
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• pp.409-415
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• 2013

본 논문에서는 코사인 위상 이진 옵셋 반송파 (binary offset carrier: BOC) 신호 추적에 알맞은 새로운 비모호 상관함수를 제안한다. 구체적으로는 코사인 위상 BOC 신호를 의사잡음코드의 칩 하나 안에 다수의 부반송파 펄스가 존재하는 형태로 해석하고, 그에 따른 새로운 국소신호들을 설계한다. 이후 새로운 국소신호들과 수신된 코사인 위상 BOC 신호를 상관하여 재조합함으로써 주변 첨두가 없는 새로운 비모호 상관함수를 생성한다. 모의실험을 통해 제안한 상관함수를 이용한 경우 기존의 상관함수들을 이용한 경우들에 비해 더욱 향상된 추적 오차 표준편차를 가지는 것을 확인한다.

• Animal Systematics, Evolution and Diversity
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• 제29권4호
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• pp.272-278
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• 2013

Accurate identification of fish and fish products, from eggs to adults, is important in many areas. Grey mullets of the family Mugilidae are distributed worldwide and inhabit marine, estuarine, and freshwater environments in all tropical and temperate regions. Various Mugilid species are commercially important species in fishery and aquaculture of many countries. For the present study we have chosen two Mugilid genes with different phylogenetic signals: relatively variable mitochondrial cytochrome oxidase subunit I (COI) and conservative nuclear rhodopsin (RHO). We examined their diversity within and among 9 Mugilid species belonging to 4 genera, many of which have been examined from multiple specimens, with the goal of determining whether DNA barcoding can achieve unambiguous species recognition of Mugilid species. The data obtained showed that information based on COI sequences was diagnostic not only for species-level identification but also for recognition of intraspecific units, e.g., allopatric populations of circumtropical Mugil cephalus, or even native and acclimatized specimens of Chelon haematocheila. All RHO sequences appeared strictly species specific. Based on the data obtained, we conclude that COI, as well as RHO sequencing can be used to unambiguously identify fish species. Topologies of phylogeny based on RHO and COI sequences coincided with each other, while together they had a good phylogenetic signal.

• 한국광학회지
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• 제23권6호
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• pp.251-254
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• 2012

이 파장 디지털 홀로그래피는 단파장 디지털 홀로그래피에 비해 보다 큰 단차를 얻는데 사용할 수 있다. 이파장 홀로그래피 방법을 이용하기 위해서는 각각의 파장에서 얻은 홀로그램으로부터 재생된 위상 이미지 크기가 동일하여야하는데, 위상 이미지 크기는 재생거리와 파장에 의존한다. 이러한 문제점을 해결하기 위하여 프레즈렐-불루스타인 변환법이 제안되었다. 이변환법은 재생상의 크기를 재생거리와 파장에 의존하지 않고 자유롭게 만들 수 있다. 본 연구에서는 프레즈렐-불루스타인 변환법을 이파장 홀로그래피에 적용하여 파장에 의존하지 않는 동일한 위상 재생상을 얻을 수 있음을 실험적으로 확인하였다.

• Bulletin of the Korean Chemical Society
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• 제35권5호
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• pp.1409-1412
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• 2014

Sex hormones are important metabolites in vertebrates' development and reproduction. For rapid screening sex hormones, matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) is one of the promising analytical platforms, but MALDI MS faces many challenges in detecting steroids such as low ionization efficiency and matrix background interference. One potential strategy to overcome matrix interference in the low m/z region is using a cyclodextrin (CD)-supported matrix for steroid analysis since CD-supported matrixes are known to effectively suppress matrix-related ion signals. In this study, we aimed to find the optimal CD-supported matrix for the analysis of the nonderivatized sex steroids. Our results showed that the ${\alpha}CD$-supported 2,5-dihydroxybenzoic acid (DHB) matrix efficiently ionized all three major classes of sex hormones, estrogens, androgens, and progestagens, with low or no matrix background and also with high sensitivity. In addition, the ${\alpha}CD$-supported DHB matrix mainly generated molecular ions or protonated ions of sex hormones, and this enabled us to obtain information-rich tandem mass spectra which potentially lead to unambiguous identification of steroid species from complex metabolite mixtures.

• BMB Reports
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• 제48권12호
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• pp.647-654
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• 2015

Energy homeostasis in our body system is maintained by balancing the intake and expenditure of energy. Excessive accumulation of fat by disrupting the balance system causes overweight and obesity, which are increasingly becoming global health concerns. Understanding the pathogenesis of obesity focused on studying the genes related to familial types of obesity. Recently, a rare human genetic disorder, ciliopathy, links the role for genes regulating structure and function of a cellular organelle, the primary cilium, to metabolic disorder, obesity and type II diabetes. Primary cilia are microtubule based hair-like membranous structures, lacking motility and functions such as sensing the environmental cues, and transducing extracellular signals within the cells. Interestingly, the subclass of ciliopathies, such as Bardet-Biedle and Alström syndrome, manifest obesity and type II diabetes in human and mouse model systems. Moreover, studies on genetic mouse model system indicate that more ciliary genes affect energy homeostasis through multiple regulatory steps such as central and peripheral actions of leptin and insulin. In this review, we discuss the latest findings in primary cilia and metabolic disorders, and propose the possible interaction between primary cilia and the leptin and insulin signal pathways which might enhance our understanding of the unambiguous link of a cell's antenna to obesity and type II diabetes.

• 대한의생명과학회지
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• 제11권4호
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• pp.429-434
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• 2005

Apolipoprotein E (apoE) restriction isotyping used oligonucleotides to amplify apoE gene sequences containing amino acid positions 112 and 158. The amplification products were digested with HhaI and subjected to electrophoresis on $4\%$ agarose gel. Each of the isoforms was distinguished by a unique combination of HhaI fragment sizes that enabled unambiguous typing of all homozygotic and heterozygotic combinations. HhaI cleaves at GCGC encoding 112arg (E4) and 158arg (E3, E4), but does not cut at GTGC encoding 112cys (E2, E3) and] 58cys (E2). DNA was isolated from 72 study participants and apoE genotypes were determined utilizing the polymerase chain reaction and restriction isotyping. In the entire group of subjects, $38 (52.8\%)$ had apo E4/4 or E3/4 (Group E4), $28(38.9\%)$ had the apo E3/3 genotype (Group E3) and $6(8.3\%)$ had apo E2/2 or E2/3 (Group E2). This genotypic information may help to identify individuals at increased risk for several diseases.

• 한국정밀공학회지
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• 제23권3호
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• pp.22-31
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• 2006

This paper introduces an approach to an ontology-based knowledge framework for product life cycle management (PLM). Participants in a product life cycle want to share comprehensive product knowledge without any ambiguity and heterogeneity. However, previous knowledge management approaches are limited in providing those aspects. Therefore, we suggest an ontology-based knowledge framework including knowledge maps, axioms and specific knowledge far domain. The bottom level, the axiom, specifies the semantics of concepts and relations of knowledge so that ambiguity of the semantics can be alleviated. The middle level is a product development knowledge map; it defines the concepts and the relations of the product domain common knowledge and guides engineers to process their engineering decisions. The middle level is then classified further into more detailed levels, such as generic product level, specific product level, product version level, and product item level for PLM. The top level is specialized knowledge fer a specific domain that gives the solution of a specific task or problem. It is classified into three knowledge types: expert knowledge, engineering function knowledge, and data-analysis-based knowledge. This proposed framework is based on ontology to accommodate a comprehensive range of unambiguous knowledge for PLM and is represented with first-order logic to maintain a uniform representation.

• 한국안전학회지
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• 제27권5호
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• pp.179-184
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• 2012

This study was performed to find out the measurement criteria of slip resistance from analysis of human gait and slips. Many kinds of slip resistance testers were developed based on mechanical friction testers. But, there are, as yet, no unambiguous slip resistance measurement methodologies and generally accepted safety criteria or safety thresholds for estimating slipping hazard exposures. Also, there are variety of measuring conditions between those testers. The measurement criteria should be tested within the range of human slipping conditions observed in biomechanical studies. It's results should clearly consider whether the devices reflect the human slipping conditions. In this study a dragsled type friction tester, which was constructed in accordance with ISO 15133 basically, was used. Test conditions were set in order to determine the range of measurement criteria. It is shown that drag velocity should be more than 1 m/s, acceleration be more than 10 $m/s^2$, contact time be less than 0.1sec, and contact pressure be within 350~400 kPa.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권4호
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• pp.1359-1375
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• 2015

Energy efficiency is critical for Wireless Sensor Networks (WSNs) since sensor nodes usually have very limited energy supply from battery. Sleep scheduling and nodes cooperation are two of the most efficient methods to achieve energy conservation in WSNs. In this paper, we propose an adaptive energy optimization approach for target tracking applications, called Energy-Efficient Node Coordination (EENC), which is based on the grid structure. EENC provides an unambiguous calculation and analysis for optimal the nodes cooperation theoretically. In EENC, the sleep schedule of sensor nodes is locally synchronized and globally unsynchronized. Locally in each grid, the sleep schedule of all nodes is synchronized by the grid head, while globally the sleep schedule of each grid is independent and is determined by the proposed scheme. For dynamic sleep scheduling in tracking state we propose a multi-level coordination algorithm to find an optimal nodes cooperation of the network to maximize the energy conservation while preserving the tracking performance. Experimental results show that EENC can achieve energy saving of at least 38.2% compared to state-of-the-art approaches.

• Journal of Computing Science and Engineering
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• 제10권3호
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• pp.85-94
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• 2016

We propose a model-based method for information alignment using educational standards as a case study. Discrepancies and inconsistencies in educational standards across different states/cities hinder the retrieval and sharing of educational resources. Unlike existing educational standards alignment systems that only give binary judgments (either "aligned" or "not-aligned"), our proposed system classifies each pair of educational standard statements in one of seven levels of alignments: Strongly Fully-aligned, Weakly Fully-aligned, Partially-$aligned^{***}$, Partially-$aligned^{**}$, Partially-$aligned^*$, Poorly-aligned, and Not-aligned. Such a 7-level categorization extends the notion of binary alignment and provides a finer-grained system for comparing educational standards that can broaden categories of resource discovery and retrieval. This study continues our previous use of mathematics education as a domain, because of its generally unambiguous concepts. We adopt a materialization pattern (MP) model developed in our earlier work to represent each standard statement as a verb-phrase graph and a noun-phrase graph; we align a pair of statements using graph matching based on Bloom's Taxonomy, WordNet, and taxonomy of mathematics concepts. Our experiments on data sets of mathematics educational standards show that our proposed system can provide alignment results with a high degree of agreement with domain expert's judgments.