• Natural Product Sciences
• /
• 제20권3호
• /
• pp.182-190
• /
• 2014

An ultra-performance liquid chromatography (UPLC) coupled with electrospray ionization (ESI) tandem mass spectrometry (MS) method was established for quantitative analysis of twelve components, allantoin (1), morroniside (2), 5-hydroxymethyl-2-furfural (5-HMF) (3), loganin (4), coumarin (5), cinnamic acid (6), mesaconitine (7), cinnamaldehyde (8), hypaconitine (9), aconitine (10), alisol B (11), and alisol B acetate (12) in a Palmijihwang-hwan decoction. The twelve constituents were separated on a UPLC BEH C18 column ($2.1{\times}100mm$, $1.7{\mu}m$) at a column temperature of $40^{\circ}C$ by gradient elution with 0.1% (v/v) formic acid in water and acetonitrile as the mobile phase. The flow rate was 0.3 mL/min and the injection volume was $2.0{\mu}L$. Calibration curves of all compounds were acquired with values of the correlation coefficient ${\geq}0.99$ within the test ranges. The limits of detection and quantification for all analytes were 0.01 - 4.53 ng/mL and 0.03 - 13.60 ng/mL, respectively. The concentrations of the compounds 1 - 9 and 12 were 72.83, 4389.00, 4859.00, 3155.17, 223.67, 33.50, 1.97, 518.00, 2.25, and $25.00{\mu}g/g$, respectively. However, compounds 10 and 11 were not detected.

• Journal of the Korean Data and Information Science Society
• /
• 제22권4호
• /
• pp.735-740
• /
• 2011

최근 전자기기의 소형화, 인텔리전트화, 다기능화, 광대역화에 관심이 집중되어 많은 발전이 이루어졌으며, 이들 전자기기들에 이용되는 모듈형의 전원장치 (SMPS : Switching-mode power supply)도 소형화, 경량화, 고효율화, 고신뢰성화, 저노이즈화를 실현하고 있다. 85~265 볼트교류전압(VAC : Voltage alternating current) 상용 전원을 공급받아 DC 출력을 공급하는 전원장치인 파워모듈은 마이크로컨트롤러, 릴레이 등 전기, 전자 회로용 전원 공급기를 간단하고 쉽게 설계하도록 개발되고 있다. 이 모듈은 전원을 사용하는 장비에 광범위하게 적용할 수 있어 에너지 절감이라는 세계적인 대과제에 적합한 제품이기는 하나 제품의 품질과 성능에 대한 통계적분석이 필요한 바 적용제품의 부하별, 출력전압별 성능분석을 하여 그 문제점을 찾아보려고 한다.

• 한국생산제조학회지
• /
• 제25권4호
• /
• pp.295-300
• /
• 2016

In the design of passive and active boring bars, the structural dimensions and shape of the vibration control boring bar are modified depending on the diameter and depth of the workpiece, which changes the dynamic behavior. Thus, the natural frequency, effective mass, and stiffness for the main structure of a tube-type boring bar need to be reset for each vibration control case. However, commercial finite element method (FEM) software and experimental modal analysis are mostly used at present despite being too time-consuming. To overcome the weaknesses of the two methods currently used for vibration control, we realized a graphical user interface (GUI) program for the modal analysis of a modified tube-type damping structure. The analysis results with the GUI program were compared to those with commercial FEM software in order to confirm the effectiveness of the former.

• 한국분말야금학회:학술대회논문집
• /
• 한국분말야금학회 2006년도 Extended Abstracts of 2006 POWDER METALLURGY World Congress Part 1
• /
• pp.39-40
• /
• 2006

The relationship between the powder particle size change and a mechanical property of the Metal Injection Molding (MIM) product was examined in detail. The XRD results indicate that the diffraction peaks of BCC appeared in compacts of powder particle size of 4 to $10{\mu}m$ as well as the bulk SUS630. However, the diffraction peaks from both BCC and FCC were observed in the compact with powder size less than $3{\mu}m$. TEM observation revealed that the powder with those BCC/FCC two phase structure have a finely dispersed $SiO_2$ precipitates. Because the Si is ferrite stabilizing element, decrease of Si composition in the matrix phase by the $SiO_2$ precipitation resulted in formation of the retained austenite. Therefore, controlling the elements such as Si as well as oxygen decrease is very important to obtain a normal microstructure in ultra-fine powder $(<3{\mu}m)$ injection molding.

• 소성∙가공
• /
• 제31권4호
• /
• pp.186-193
• /
• 2022

The application of UHSS sheet is being expanded up to 50% to reduce the weight of automobiles and improve safety. However, due to the high strength and low elongation of the ultra-high tensile strength steel sheet, product defects such as spring back and mold defects such as cracks and chippings also occur. In this study, Pin/Ring on Disc and Spiral wear tests were conducted to evaluate the durability of Ti/Cr-coated molds for forming 1.2GPa grade UHSS sheets. Component analysis and thickness were measured for each coating layer, and hardness and adhesion were investigated to determine mechanical properties. Combining the results of various wear tests, it was found that the TiAlN coating had the best wear and sticking resistance.

• 한국전자통신학회논문지
• /
• 제11권4호
• /
• pp.403-410
• /
• 2016

금속으로 이루어진 물질의 경우에는 고유하며 명백한 공진 주파수를 가지고 있다. 이러한 성질을 이용하여, 공장에서 만들어진 제품의 품질 테스트를 실행할 수 있다. 해당 제품에 충격을 가하고 이로부터 발생되는 소리나 진동의 주파수를 고성능의 장비를 이용하여 측정하게 된다. 범용 컴퓨터나 DSP 기반의 단독 시스템들이 이를 위해서 사용되며 이러한 장비들은 들고 다니기에 크기가 너무 크고 구축비용이 많이 든다. 본 논문에서는 TI의 MSP430 계열의 MCU를 이용하여 개발된 시스템에 대하여 소개하고자 한다. 초저전력의 MSP430 MCU들은 큰 용량의 배터리가 필요 없으므로 매우 작은 크기의 주파수 분석기를 제작하는 것이 가능하게 한다. 제안된 시스템은 검사원이 쉽게 장비를 가지고 다닐 수 있어야 하고 정확도를 다소 희생하더라도 작은 개발비용이 요구되는 환경에 사용될 수 있을 것이다. 제안된 시스템은 론치패드를 이용하여 개발되었으며, 인위적이거나 자연스런 소리의 주파수를 매우 높은 정확도로 판별 할 수 있음을 확인할 수 있었다.

• 대한융합한의학회지
• /
• 제2권1호
• /
• pp.5-12
• /
• 2021

Objectives: The purpose of this study is to fabricate an ultra-fine ginsenoside particle atomizer that can provide a new treatment method by delivering ginsenoside components that have a therapeutic effect on respiratory diseases directly to the lungs. Methods: We fabricated the AAO vibrating mesh by using the micromachining process. The starting substrate of an AAO wafer has a 350nm pore diameter with 50㎛ thickness. A photomask having several 5㎛ opening holes with a 100㎛ pitch was used to separate each nanopore nozzle. The photoresist structure was optimized to pattern the nozzle area during the lift-off process precisely. The commercial vibrating mesh was removed from OMRON's NE-U100 product, and the fabricated AAO vibrating mesh was installed. A diluted sample of 20mL with 30% red ginseng concentrate was prepared to atomize from the device. Results: As a result of liquid chromatography analysis before spraying the ginsenoside solution, ginsenoside components such as 20S-Rg3, 20R-Rg3, and Rg5 were detected. After spraying through the AAO vibrating mesh, ginsenosides of the same component could be detected. Conclusion: A nutrient solution containing ginsenosides was successfully sprayed through the AAO vibrating mesh with 350 nm selective pores. In particular, during the atomizing experiment of ginsenoside drug solution having excellent efficacy in respiratory diseases, it was confirmed that atomizing through the AAO vibrating mesh while maintaining most of the active ingredients was carried out.

• Journal of Applied Biological Chemistry
• /
• 제66권
• /
• pp.467-476
• /
• 2023

오미자(Schisandra chinensis)는 오미자과에 속하는 낙엽활엽덩굴식물로 한국, 일본, 중국, 대만 등 동아시아에 널리 분포한다. 오미자에 함유된 주요 성분에는 리그난 화합물뿐만 아니라 트리테르페노이드 화합물도 포함되어 있는 것으로 보고되었다. 한국 산지별 오미자의 특성을 구별하기 위해 대사산물 프로파일링과 다변량 통계 분석 기법인 PCA을 수행하여 판별식을 설정하였고, 그 결과 triterpenoids 16종, lignan 9종, flavonoid, phenylpropanoid, fatty acid 각 1종을 동정하였다. 또한 다변량 통계분석을 통해 OPLS-DA의 s-plot 모델을 적용하여 단양, 문경, 거창, 평창의 4개 그룹을 구분하는 것을 확인하였고, lanostane, cycloartane, 그리고 schiartane triterpenoid, dibenzocyclooctadiene lignan 이 각각 화학적마커로 동정하였다.

• Progress in Superconductivity
• /
• 제14권2호
• /
• pp.82-86
• /
• 2012

A sensitive eight-channel high-Tc Superconducting Interference Device (SQUID) detection system for magnetic contaminant in a lithium ion battery anode was developed. Finding ultra-small metallic foreign matter is an important issue for a manufacturer because metallic contaminants carry the risk of an internal short. When contamination occurs, the manufacturer of the product suffers a great loss from recalling the tainted product. Metallic particles with outer dimensions smaller than 100 microns cannot be detected using a conventional X-ray imaging system. Therefore, a highly sensitive detection system for small foreign matter is required. We have already developed a detection system based on a single-channel SQUID gradiometer and horizontal magnetization. For practical use, the detection width of the system should be increased to at least 65 mm by employing multiple sensors. In this paper, we present an 8-ch high-Tc SQUID roll-to-roll system for inspecting a lithium-ion battery anode with a width of 65 mm. A special microscopic type of a cryostat was developed upon which eight SQUID gradiometers were mounted. As a result, small iron particles of 35 microns on a real lithium-ion battery anode with a width of 70 mm were successfully detected. This system is practical for the detection of contaminants in a lithium ion battery anode sheet.