• Title/Summary/Keyword: u-병원 환경

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Immunogenicity and Reactogenicity of Inactivated HM175 Strain Hepatitis A Vaccine in Healthy Korean Children (건강한 한국 소아에서 HM175주 A형 간염 불활화 백신의 면역원성 및 이상반응에 관한 연구)

  • Kim, Chang Hwi;Pyun, Bok Yang;Hong, Young Jin;Kang, Jin Han
    • Pediatric Infection and Vaccine
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    • v.7 no.1
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    • pp.120-128
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    • 2000
  • Purpose : Active immunization against hepatitis A with an inactivated vaccine reveals excellent immunogenicity, tolerability and protective efficacy. Inactivated hepatitis A vaccines have been selectively used since 1996 in Korea to prevent hepatitis A. This study was performed to assess the immunogenicity and reactogenicity after two doses of HM175 strain hepatitis A vaccine in healthy Korean children. Methods : 128 healthy children(M/F; 65/63) aged 1 to 15 years, who were seronegative for hepaitatis A, participated in this study. A alum-adsorbed vaccine containing 720 EL.U of antigen form HM175 hepatitis A strain per 0.5 mL dose was injected intramuscularly on the deltoid area. The second dose was given 6 months later, Anti-HAV antibodies were measured by ELISA before and 1 month after each vaccination to assess the immunogenicity. Any local and general adverse events were reported by patients parents with the prepared questionnaire after each vaccination. Results : 120 volunteers(M/F; 60/60) completed the whole series of the study. Seroconversion occurred in all cases after primary and booster vaccination. The mean anti-HAV antibody titer after primary vaccination was 389.2mIU/mL, and 3,609mIU/mL after booster vaccination. And levels of anti-HAV antibodies after booster immunization were significantly higher in female children. The most common local adverse event was soreness on the injection site, but it was mild and resolves within 3 days. Fever was not reported after booster vaccination. Conclusion : Based on these data, we conclude that the inactivated HM175 strain hepatitis A vaccine is highly immunogenic and tolerable in healthy Korean children.

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Visible Light Communication Based Wide Range Indoor Fine Particulate Matter Monitoring System (가시광통신 기반 광역 실내 초미세먼지 모니터링 시스템)

  • Shakil, Sejan Mohammad Abrar;An, Jinyoung;Han, Daehyun;Chung, Wan-Young
    • Journal of the Institute of Convergence Signal Processing
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    • v.20 no.1
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    • pp.16-23
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    • 2019
  • Fine particulate matter known as PM 2.5 refers to the atmospheric particulate matter that has a diameter less than 2.5 micrometer identified as dangerous element for human health and its concentration can provide us a clear picture about air dust concentration. Humans stay indoor almost 90% of their life time and also there is no official indoor dust concentration data, so our study is focused on measuring the indoor air quality. Indoor dust data monitoring is very important in hospital environments beside that other places can also be considered for monitoring like classrooms, cements factories, computer server rooms, petrochemical storage etc. In this paper, visible light communication system is proposed by Manchester encoding technique for electromagnetic interference (EMI)-free indoor dust monitoring. Important indoor environment information like dust concentration is transferred by visible light channel in wide range. An average voltage-tracking technique is utilized for robust light detection to eliminate ambient light and low-frequency noise. The incoming light is recognized by a photo diode and are simultaneously processed by a receiver micro-controller. We can monitor indoor air quality in real-time and can take necessary action according to the result.

Design and development of clear aligner management system using QR code (QR 코드를 활용한 투명 교정장치 관리 시스템 설계 및 개발)

  • Jang, Jin-Su;Son, Ho-Jung;Sim, Ji-Young;Kang, Sin-Yeong;Moon, Jun-Mo;Lee, Tae-Ro
    • Journal of Digital Convergence
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    • v.17 no.9
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    • pp.185-192
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    • 2019
  • The introduction of smart technology provides accuracy, safety, and efficiency to both physicians and patients. Although interest in a clear aligner is increasing among users worldwide, the current clear aligner requires a visit to the hospital every one or two weeks for replacement, which is a very cumbersome process. There is also confusion among dentists and patients because about 40 to 80 devices are made, and calibration is done based on the order and duration of the clear aligner. Therefore, this study designed and developed a clear aligner management system so that communication between the patient and dentist can be smoothly performed by inserting the QR code into the transparent correction device. As a result, the size of the QR code was recognized as $6{\ast}6mm^2$ which can be used in the oral and the recognition distance was 100% within 12 cm. Since the dentist can remotely manage the patient with the proposed system and improve the correction effect, it is possible to manage patients abroad, as well as domestically.

A Study on Health Risk Assessment by Exposure to Organic Compounds in University Laboratory (대학 실험실에서의 유기화합물 노출에 의한 건강위험성 평가에 관한 연구)

  • Sim, Sanghyo;Won, Jung-II;Jeon, Hasub;Kim, Dowon
    • The Journal of Korean Society for School & Community Health Education
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    • v.22 no.4
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    • pp.49-60
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    • 2021
  • Objectives: Laboratories have various latent physical, chemical, biological, and ergonomical factors according to the diversification and fusion of research and development activities. This study aims to investigate the chemical exposure concentrations of college laboratories and evaluate their health risks, and use them as basic data to promote the health of college students. Methods: The sampling and analysis of harmful chemicals in the air in laboratories were performed using Method 1500 of the U.S. National Institute for Occupational Safety and Health (NIOSH)의 Method 1500. The harmful chemicals in the laboratories were divided into carcinogenic and non-carcinogenic chemicals. Risk assessment was performed using the cancer risk (CR) for carcinogenic chemicals and using the hazard index (HI) for non-carcinogenic chemicals. Results: The harmful chemicals in college laboratories consisted of acetone, diethyl ether, methylene chloride, n-hexane, ethyl acetate, chloroform, tetrahydrofuran, toluene, and xylenes. They showed the highest concentrations in laboratories A (acetone 0.001~2.34ppm), B (chloroform 0.95~6.35ppm), C (diethyl ether 0.08~8.68ppm), and D (acetone 0.07~14.96ppm). The risk assessment result for non-carcinogenic chemicals showed that the HI of methylene chloride was 2.052 for men and 2.333 for women, the HI of N-hexane was 4.442 for men and 5.05 for women. Thus, the HI values were higher than 1. The risk of carcinogenic chemicals is determined by an excess cancer risk (ECR) value of 1.0×10-5, which means that one in 100,000 people has a cancer risk. The ECRs of chloroform exceeded 1.0×10-5 for both men and women, indicating the possibility of cancer risk. Conclusion: College laboratories showed the possibility of non-carcinogenic health risks for methylene chloride, n-hexane, tetrahydrofuran (THF), toluene, and xylenes, and carcinogenic health risks for chloroform, methylene chloride. However, this study used the maximum values of measurements to determine the worst case, and assumed that the subjects were exposed to the corresponding concentrations continuously for 8 hours per day for 300 days per year. In consideration of the nature of laboratory environment in which people are intermittently exposed, rather than continuously, to the chemicals, the results of this study has an element of overestimation.

A Study of Potential Application of the Analytic Hierarchy Process in Nursing; Predicting the Future of Nursing Education in the U.S. (계층분석과정의 간호적용에 관한 연구 -미국의 미래 간호교육의 예견-)

  • Han, Kyung-Ahe
    • Journal of Korean Academy of Nursing
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    • v.16 no.1
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    • pp.89-104
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    • 1986
  • 복잡한 사회문제해결에 유용한 접근방법의 하나인 계층분석과정은 수학자인 사티(Saaty)가 개발한 것으로서 이미 사회과학의 여러 분야에 적용되고 있다. 본 논문의 목적은 이 계층분석과정을 간호교육과 관련된 문제에 적용해 봄으로써 이 방법이 실제 문제해결을 위한 유용한 접근방법이 될 수 있는가를 고찰해 보는데 있다. .현대사회문제들은 다양한 관련요소, 그 요소들간이나 다른 문제들과의 복잡한 상호관계, 다수의 의사결정자의 참여, 무한한 대안, 문제의 결과에 대한 불확실성 등으로 인하여 단순한 모델이나 간단한 논리적 혹은 직관적인 판단에 준하여 일시에 해결하기 어려운 경우가 많다. 이러한 상황 하에서 문제와 관련된 요소들을 찾아내고 그 요소들을 계층적으로 분석하여 단계적으로 문제해결에 접근하는 계층분석과정을 활용함으로써 사회과학분야의 문제해결에 유용한 수단이 될 수 있다. 또한 문제와 관련된 요소를 규명하고 계층적으로 분화하는 과정에서 그 문제에 대한 보다 명확한 이해, 분석 및 현상의 흐름을 더 잘 인해하게 된다. 계층분석과정은 1) 계층구조의 설정 2) 구성요소들의 중요도 측정 3) 중요도에 따른 우선 순위의 산정 4) 우선 순위의 일관성 검토과정으로 요약된다. 본 논문에서는 이러한 과정을 통하여 미국 간호계에서 심각한 문제로 대두되어온 기본교육제도상의 쟁점(Issue of Entry into Practice)에 대한 문제 해결책이 마련되는지를 시도하였다. 즉, 기본교육 제도에 영향을 미칠 수 있는 요인들을 규명하여 계층화하고 계층내에 위치하는 구성요소들의 수평적 관계와 계층간의 수직적 관계를 체계적으로 검토하여 간호교육의 미래를 예측해 보았다. 간호교육제도에 영향을 미칠 수 있는 주요 요인들의 계층화는 거시적 환경차원(factors), 관련 이해자 집단차원(actors), 이해자 집단의 목표차원(objectives), 목표달성을 위한 정책차원(Policies), 그리고 간호교육제도의 미래를 예견한 시나리오(scenario)로 이루어졌다. 각 계층을 따라 단계적으로 중요도를 비교하여 최종적으로 각 시나리오의 우선순위 중요도(priority weight)를 구하였다. 각 시나리오의 우선순위 중요도를 간호교육과 관련된 4가지 차원들(학생, 교수, 교육기관, 직업)을 구성하고 있는 특성들에 가중하여 결과를 해석 하였다. 간호교육의 미래에 정치적(55%)과 경제적(25%) 요인이 가장 강한 영향을 미치고, 관련자중에서는 병원(38%) 의사(33%) 그리고 정부(23%)의 순으로 영향을 미친다고 분석되었다. 의외로 간호원 자신들은 큰 영향력이 없는 것으로 보여졌다. 4개의 시나리오 중에서는 그 우선순위 중요도가 현상유지(33%) 자발적4년제(32%), 강제 4년제(19%), 그리고 2~3년제의 우위(18%) 순으로 나타났다. 최종 시나리오 결과를 요약하면 1) 전체 학생수는 감소하나 양질의 간호학생수는 증가하며 2) 박사학위를 소지한 간호학 교수 및 전체 교수의 수가 증가할 것이다. 3) 전체 간호교육기여의 수는 약간 줄 것이며 그중 4년제 기관이 증가하고 반면에 2~3년제의 기관은 감소할 것이다. 4) 전문간호원이 되기 위한 입학용이도에는 별차이가 없겠으나 간호원들의 보수, 지위 및 자율성이 증가하면서 전반적인 간호의 질이 향상될 것이다. 계층분석과정의 적용으로 미국 간호교육계의 가까운 미래를 위와 같이 예견하여 보았으나 이 과정은 예견 뿐 만 아니라 일반적인 의사결정이나 문제 해결의 도구이외에도 복잡한 사회문제의 본질을 분석, 이해함으로써 보다 정화한 정책문제를 규정하는 데에도 유용할 것이다.

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The Experiences of Nursing Student's Introductory Clinical Practice (간호대학생의 임상입문실습 경험)

  • Kim, Hyun-Ju;Song, Hoo-Seung
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.2
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    • pp.74-84
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    • 2020
  • This study was conducted to discover the meaning and the essential structure of the experiences of nursing students' introductory clinical practice. The participants were eight nursing students who had carried out the introductory clinical practice at a hospital. The data was collected from July 15 2019 to July 31, 2019 through focus group discussions and in-depth individual interviews using non-structured questionnaires. The data was analyzed by Colaizzi's phenomenological analysis methodology. The introductory clinical practice experienced by nursing students was categorized as followed: 'Feel worried and concern about expectations at the same time', 'Hospital experience as reality', 'Becoming accustomed to complexed emotion's, 'The first step of becoming a nurse', and 'Preparation for the future'. The five categories were expanded in the same context according to time. The essential structure of the clinical introductory practice experiences of the nursing students revealed by the study is that they begin to practice feeling worried and concerned about expectations, and concern about experience and adaption to various situations, emotions and preparation for the future. Based on the results obtained from this study, it is necessary to develop a realistic and effective education program before starting clinical practice.

Restriction endonuclease analysis of mitochondrial DNA of Acanthamoebn sp. YM-4 (Korean isolate) (Acanrhamoeba sp. YM-4의 미토콘드리아 DNA의 RFLP분석)

  • Sin, Ho-Jun;Im, Gyeong-Il;Jeon, Gwang-U
    • Parasites, Hosts and Diseases
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    • v.35 no.2
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    • pp.119-126
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    • 1997
  • Acanthnmoebn sp. YM-4 is simitar to A. culbertsoni based upon morphological characteristics of trophozoites and cysts. However, based on other characteristics, pathogenicity to mice, in uitro cytotoxicity and isoenzyme patterns, Acanthomoebo sp. YM- 4 was quite different from A. culbertsoni. Restriction fragment length polymorphism (RFLP) analysis of mtDNA is useful in the classification of members belonging to the genus Acanthcmoebn. Therefore, in this study, RFLP analysis of Acnnthcmoeba mtDNAs was accomplished using five restriction enzymes: Hnelll, Hinull, Clcl, Pudl and ScE. Each restriction enzyme produced approximately 3-15 fragments (range: from 0:6 kip to 34.4 kbp) . The mtDNA genome size, calculated by the summation of restriction fragments, averaged 46.4 kbp in Acnnthamoeba sp. YM-4,48.3 kbp in A. culbertsoni and 48.8 kbp in A. polyphaic, respectively. Digested mtDNA fragments of Accnthcmoeba sp. YM-4 contained nine and seven same size fragments, respectively, from a total of 67 and 69 fragments observed in A. culbertsoni and A. polyphcgn. An estimate of the genetic divergence was 10.1% between Acanthamoebc sp. YM-4 and A. culbertsoni, and 9.9% between Acanthamoebn sp. YM-4 and A. polyphcga.

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The Implementation of a HACCP System through u-HACCP Application and the Verification of Microbial Quality Improvement in a Small Size Restaurant (소규모 외식업체용 IP-USN을 활용한 HACCP 시스템 적용 및 유효성 검증)

  • Lim, Tae-Hyeon;Choi, Jung-Hwa;Kang, Young-Jae;Kwak, Tong-Kyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.42 no.3
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    • pp.464-477
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    • 2013
  • There is a great need to develop a training program proven to change behavior and improve knowledge. The purpose of this study was to evaluate employee hygiene knowledge, hygiene practice, and cleanliness, before and after HACCP system implementation at one small-size restaurant. The efficiency of the system was analyzed using time-temperature control after implementation of u-HACCP$^{(R)}$. The employee hygiene knowledge and practices showed a significant improvement (p<0.05) after HACCP system implementation. In non-heating processes, such as seasoned lettuce, controlling the sanitation of the cooking facility and the chlorination of raw ingredients were identified as the significant CCP. Sanitizing was an important CCP because total bacteria were reduced 2~4 log CFU/g after implementation of HACCP. In bean sprouts, microbial levels decreased from 4.20 logCFU/g to 3.26 logCFU/g. There were significant correlations between hygiene knowledge, practice, and microbiological contamination. First, personnel hygiene had a significant correlation with 'total food hygiene knowledge' scores (p<0.05). Second, total food hygiene practice scores had a significant correlation (p<0.05) with improved microbiological qualities of lettuce salad. Third, concerning the assessment of microbiological quality after 1 month, there were significant (p<0.05) improvements in times of heating, and the washing and division process. On the other hand, after 2 months, microbiological was maintained, although only two categories (division process and kitchen floor) were improved. This study also investigated time-temperature control by using ubiquitous sensor networks (USN) consisting of an ubi reader (CCP thermometer), an ubi manager (tablet PC), and application software (HACCP monitoring system). The result of the temperature control before and after USN showed better thermal management (accuracy, efficiency, consistency of time control). Based on the results, strict time-temperature control could be an effective method to prevent foodborne illness.

The Acceptance Testing of 5 Mega Pixels Primary Electronic Display Devices and the Study of Quality Control Guideline Suitable for Domestic Circumstance (5 Mega 화소 진단용 전자표시장치 인수검사 및 국내 실정에 적합한 정도관리 가이드라인 연구)

  • Jung, Hai-Jo;Kim, Hee-Joung;Kim, Sung-Kyu
    • Progress in Medical Physics
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    • v.18 no.2
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    • pp.98-106
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    • 2007
  • In June 2005, Yonsei University Medical Center, Severance Hospital upgraded a full-PACS system by adding twenty (5 mega pixels) Totoku ME511L flat panel LCD display devices for diagnostic interpretation purposes. Here we report upon the quantitative (or visual) acceptance testing of the twenty Totoku ME511L display devices for reflection, luminance response, luminance spatial dependency, resolution, noise, veiling glare, and display chromaticity based on AAPM TG 18 report. The tools used in the tests included a telescopic photometer, which was used as a colorimeter, illuminance meter, light sources for reflection assessment, light-blocking devices, and digital TG18 test patterns. For selected 8 flat panel displays, mean diffuse reflection coefficient ($R_d$) was $0.019{\pm}0.02sr^{-1}$. In the luminance response test, luminance ratio (LR), maximum luminance difference ($L_{max}$), and deviation of contrast response were $550{\pm}100,\;2.0{\pm}1.9%\;and\;5.8{\pm}1.8%$, respectively. In the luminance uniformity test, maximum luminance deviation was $14.3{\pm}5.5%$ for the 10% luminance of the TG18-UNL10 test pattern. In the resolution test with luminance measurement method, percent luminance (${\Dalta}L$) at the center was $0.94{\pm}0.64%$. In all cases of noise testing, rectangular target In every square in the three quadrants was visible and all 15 targets except the smallest one in the every corner pattern and the center pattern. The glare ratio (GR) was $12,346{\pm}1,995$. The color uniformity, (u',v'), was $0.0025{\pm}0.0008$. Also, the research results of qualify control guideline of primary disply devices suitable for domestic circumstance are presented All test results are in-line with the criteria recommended by AAPM TG18 report and are thus fully acceptable for diagnostic image interpretation. As a result, the acceptance testing schedule described provides not only an acceptance standard but also guidelines for quality control, optimized viewing conditions, and a means for determining the upgrading time of LCD display devices for diagnostic interpretation.

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A Study on the Traumatic Teeth Damage of Children (어린이의 외상성 치아손상에 관한 연구)

  • Yoo, Su-Min;Park, Ho-won
    • Journal of dental hygiene science
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    • v.4 no.1
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    • pp.21-25
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    • 2004
  • In modern times, children's trauma is increasing every year because of car accidents and life environment changes. There is a limit to prevent traumatic damage for oral cavity organization. The fundamental data of trauma treatment and prevention will be presented through the survey and analysis of traumatic teeth damage. I examined 113 patients from Oct. 4th, 2000 to Feb. 27th, 2004 at Dept. of Children's Dental Clinic, Kangnung National University. The results are as follows. (1) The trauma frequency of male subjects is higher than that of female at a rate of 2.05:1. The average age is 5.27 for men and 5.27 for women. The highest percentage of trauma patients is among 2 year old children. It is 21.2%. (2) A patient survey was taken at a trauma treatment hospital. On the first day 34.4% of the patients had come to receive treatment of their first set of teeth. However, after a week, 38.8% of the patients had received treatment on their permanent teeth. (3) As a result of falling, 59% of patients needing treatment on their first set of teeth. 55.1% of patients is permanent teeth. As a result of bump against physical solid, 26.6% of patients is the first set of teeth and 26.5% of patients is permanent teeth. (4) Teeth damage happened at home. 42.1% were male. 35.1% were female. According to trauma, 59.4% of teeth damage happened at home. 28.6% of permanent teeth damage happened at school or kindergarten. (5) According to trauma, the number of teeth damaged was in the first set of teeth are as follows: 56.3%, one-31.3%, three or four-6.3% each. For permanent teeth: two-46.9%, one-28.6%, four over-16.3% and three-8.2%. Over four teeth is larger number for permanent teeth. (6) 56% of first set of teeth patients and 43.4% of permanent teeth patients were male. 56.8% of first set of teeth patients and 43.2% of permanent teeth were female. Trauma happened to both male and female frequently in the first set of teeth. (7) Most of the tooth damage which was in the first set of teeth and permanent teeth was done to the upper jaw. 75% of patients are the first set of teeth. 63.8% of patients are permanent teeth. Trauma is very high in the two mid teeth of the upper jaw. (8) According to trauma survey, 30.2% is from impulse. 28.0% is from crown fracture, 14.7% is from depression. 8.9% is from concussion. 7.1% is from full dislocation of a joint. 2.2% of patients are extrusion. 1.8% is from displacement. According to teeth damage trauma, 35.8% is pulse in the first set of teeth. The breaking of the crown of a tooth happened a lot in permanent teeth. (9) According to data, 43.2% of teeth damage in the first set of teeth goes without treatment. In permanent teeth, it is 38.9%. After treatment, 22.0% of first set of teeth treatment requires a dental pulp treatment. In permanent teeth, which is used for temporary acid etching resin restoration.

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