• Title/Summary/Keyword: two-scale modeling

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Structure-based Functional Discovery of Proteins: Structural Proteomics

  • Jung, Jin-Won;Lee, Weon-Tae
    • BMB Reports
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    • v.37 no.1
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    • pp.28-34
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    • 2004
  • The discovery of biochemical and cellular functions of unannotated gene products begins with a database search of proteins with structure/sequence homologues based on known genes. Very recently, a number of frontier groups in structural biology proposed a new paradigm to predict biological functions of an unknown protein on the basis of its three-dimensional structure on a genomic scale. Structural proteomics (genomics), a research area for structure-based functional discovery, aims to complete the protein-folding universe of all gene products in a cell. It would lead us to a complete understanding of a living organism from protein structure. Two major complementary experimental techniques, X-ray crystallography and NMR spectroscopy, combined with recently developed high throughput methods have played a central role in structural proteomics research; however, an integration of these methodologies together with comparative modeling and electron microscopy would speed up the goal for completing a full dictionary of protein folding space in the near future.

Micro-Grid System Analysis (마이크로그리드 시스템 해석)

  • Son, Kwang-M.;Lee, Kye-B.
    • Proceedings of the KIEE Conference
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    • 2005.07a
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    • pp.280-282
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    • 2005
  • Micro-source units having power ratings in thousands of watts can provide even higher reliability and fuel efficiency than the conventional large scale units. These units are also clustered with loads creating micro-grid services to customer sites such as office buildings, industrial parks and homes. Micro-sources adopt voltage source inverter to ensure the power quality of sensitive loads. This paper deals with the connection of micro-sources into the system grid. Modeling and simulation of the grid connected micro-sources at the power frequency range are investigated. Simulation results show that the micro-grid system with two micro-sources has good dynamic characteristics.

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The control of Interleaved Multi-phase Boost Converter for Application of a Fuelcell Railway Vehicle (연료전지 철도차량 적용을 위한 인터리브드 다상 승압형 컨버터 제어)

  • Kim, Jae-Moon
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.65 no.11
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    • pp.1925-1930
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    • 2016
  • Fuel cell power generation system, unlike conventional energy sources, converts chemical energy into electrical energy through electrochemical reaction of hydrogen and oxygen. This paper presents the control of interleaved multi-phase boost converter as the feasibility study on small-scale prototype electric railway vehicle application using fuel cell generation system. PSIM simulation program is to be used to implement the modeling of the electrical fuelcell as well as traction motor control with interleaved multi-phase boost converter. Comparing the input current ripple rate, two-phase interleaved boost converter is less than the boost converter. But the more multi-phase not less proportional to the ripple factor. we confirmed that the amplitude of the input current ripple rate of converter depend on duty ratio.

Nonlinear modeling of flat-plate structures using grid beam elements

  • Tian, Ying;Chen, Jianwei;Said, Aly;Zhao, Jian
    • Computers and Concrete
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    • v.10 no.5
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    • pp.489-505
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    • 2012
  • This paper presents a simplified grid beam model for simulating the nonlinear response of reinforced concrete flat-plate structures. The beam elements are defined with nonlinear behavior for bending moment and torsion. The flexural stiffness and torsional strength of the beam elements are defined based on experimental data to implicitly account for slab two-way bending effects. A failure criterion that considers the interaction between the punching strength and slab flexural behavior is incorporated in the model. The effects of bond-slip of slab reinforcement on connection stiffness are examined. The proposed grid beam model is validated by simulating large-scale tests of slab-column connections subjected to concentric gravity loading and unbalanced moment. This study also determines the critical parameters for a hysteretic model used to simulate flat-plates subjected to cyclic lateral loading.

Vibration analysis of FG nanoplates with nanovoids on viscoelastic substrate under hygro-thermo-mechanical loading using nonlocal strain gradient theory

  • Barati, Mohammad Reza
    • Structural Engineering and Mechanics
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    • v.64 no.6
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    • pp.683-693
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    • 2017
  • According to a generalized nonlocal strain gradient theory (NSGT), dynamic modeling and free vibrational analysis of nanoporous inhomogeneous nanoplates is presented. The present model incorporates two scale coefficients to examine vibration behavior of nanoplates much accurately. Porosity-dependent material properties of the nanoplate are defined via a modified power-law function. The nanoplate is resting on a viscoelastic substrate and is subjected to hygro-thermal environment and in-plane linearly varying mechanical loads. The governing equations and related classical and non-classical boundary conditions are derived based on Hamilton's principle. These equations are solved for hinged nanoplates via Galerkin's method. Obtained results show the importance of hygro-thermal loading, viscoelastic medium, in-plane bending load, gradient index, nonlocal parameter, strain gradient parameter and porosities on vibrational characteristics of size-dependent FG nanoplates.

Numerical Analysis of Ventilation Effectiveness using Turbulent Airflow Modeling (난류유동해석을 통한 환기효율의 수치해석적 연구)

  • Han, H.T.
    • Korean Journal of Air-Conditioning and Refrigeration Engineering
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    • v.4 no.4
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    • pp.253-262
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    • 1992
  • A numerical procedure is introduced to calculate local ventilation effectiveness using the definitions of local decay rate and local mean age. A low Reynolds number $k-{\varepsilon}$ model is implemented to calculate steady state turbulent velocity distributions, and a step-down method is used to calculate transient concentration distributions. Simulations are carried out for several different values of air change rates and several different diffuser angles in a two-dimensional model of a half scale office room. The results show that the local ventilation effectiveness within a room could vary significantly from one location to another. The nominal air change rate based on the assumption of complete mixing of room air does not provide the local ventilation effectiveness information. It is numerically proved that the local mean age distribution obtained from the transient calculation is equivalent to the steady state concentration distribution with homogeneously distributed contaminant sources.

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On the continuum formulation for modeling DNA loop formation

  • Teng, Hailong;Lee, Chung-Hao;Chen, Jiun-Shyan
    • Interaction and multiscale mechanics
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    • v.4 no.3
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    • pp.219-237
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    • 2011
  • Recent advances in scientific computing enable the full atomistic simulation of DNA molecules. However, there exists length and time scale limitations in molecular dynamics (MD) simulation for large DNA molecules. In this work, a two-level homogenization of DNA molecules is proposed. A wavelet projection method is first introduced to form a coarse-grained DNA molecule represented with superatoms. The coarsened MD model offers a simplified molecular structure for the continuum description of DNA molecules. The coarsened DNA molecular structure is then homogenized into a three-dimensional beam with embedded molecular properties. The methods to determine the elasticity constants in the continuum model are also presented. The proposed continuum model is adopted for the study of mechanical behavior of DNA loop.

Performance evaluation of steel and composite bridge safety barriers by vehicle crash simulation

  • Thai, Huu-Tai
    • Interaction and multiscale mechanics
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    • v.3 no.4
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    • pp.405-414
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    • 2010
  • The performance of full-scale steel and composite bridge safety barriers under vehicle crash is evaluated by using the nonlinear explicit finite element code LS-DYNA. Two types of vehicles used in this study are passenger car and truck, and the performance criteria considered include structural strength and deformation, occupant protection, and post-crash vehicle behavior. It can be concluded that the composite safety barrier satisfies all performance criteria of vehicle crash. Although the steel safety barrier satisfies the performance criteria of occupant protection and post-crash vehicle behavior, it fails to satisfy the performance criterion of deformation. In all performance evaluations, the composite safety barrier exhibits a superior performance in comparing with the steel safety barrier.

The Virial Relation and Intrinsic Shape of Elliptical Galaxies

  • Trippe, Sascha
    • The Bulletin of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.32.1-32.1
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    • 2016
  • Early-type galaxies (ETGs) are supposed to follow the virial relation M ~ sigma^2 * R_e, with M being the galaxy mass, sigma being the stellar velocity dispersion, and R_e being the (2D) effective radius. I apply this relation to (a) the ATLAS3D sample and (b) the sample of Saglia et al. (2016). The two datasets reveal a statistically significant tilt of the empirical relation relative to the theoretical virial relation such that M ~ (sigma^2 * R_e)^0.92 with zero intrinsic scatter. This tilt disappears when replacing R_e with the semi-major axis of the projected half-light ellipse, a. Accordingly, a, not R_e, is the correct proxy for the scale radius of ETGs. By geometry, this implies that early-type galaxies are axisymmetric and oblate in general, in agreement with recent results from modeling based on kinematics and light distributions.

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Labyrinth Seal Effects in Turbines (터빈 실(Seal)의 유동 해석)

  • Song, Bum Ho;Song, Seung Jin
    • 유체기계공업학회:학술대회논문집
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    • 2000.12a
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    • pp.158-162
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    • 2000
  • Secondary flows in gas turbines, especially those associated tip clearance and labyrinth seals, have become a focus of interest for engine manufacturers. In the past, many analytical and experimental studies, which focused solely on the flows in either tip clearances or seals, have been conducted. This paper presents an analytical model that describes the flow response in a single stage turbine induced by a finite sealing gap at the turbine rotor. The flow is assumed to be axisymmetric and the analysis is done in the meridional plane. Upon going through the stage, the radially uniform upstream flow is assumed to split into two streams one associated with the seal and the other which has gone through the blades. The former is referred to as the leakage flow, and the latter is referred the as the passage flow. The passage flow is assumed to be inviscid and incompressible while the flow in the seal can be modeled as either inviscid or viscous. Thus, the model is capable of predicting the kinematic effects of labyrinth seals on the turbine flow field.

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