• Korean Journal of Clinical Pharmacy
• /
• v.8 no.1
• /
• pp.59-67
• /
• 1998

The stability of cytarabine (manufactured by two pharmaceutical companies) in intravenous admixture and in plastic syringe was investigated. The admixures containing cytarabine 0.35, 8.6, and 17.1 mg/ml in $0.9\%\;NaCl\;or\;5\%$ D5W were placed in PVC bags or glass bottles, and the reconstituted cytarabine (50 mg/ml) was placed in plastic syringe. One ml aliquots were withdrawn immediately after each preparation and stored at $4^{\circ}C\;or\;24^{\circ}C$ for 1, 2, 4, 6, 8, 10, and 14 days unprotected from light. Each sample was tested for pH and visually inspected for precipitation and change in color. Cytarabine concentrations were measured using high-performance liquid chromatography. Neither precipitation nor change in color was noted, and there were no change in pH during 14 days of testing. The changes in cytarabine concentrations were less than $10\%$. In conclusion, cytarabine in IV admixture or plastic syringe was stable for at least 14 days at $4^{\circ}C\;and\;24^{\circ}C.$(Kor. J. Clin. Pharm. 1998; 8(1): 59-67)

• The Journal of the Korea Contents Association
• /
• v.9 no.6
• /
• pp.1-8
• /
• 2009

There are a lot of influences, such as location of camera, luminosity, brightness, and direction of light, which affect the performance of 2-dimensional image recognition. This paper suggests an adaptive method for face-image recognition in noisy environments using evolvable filtering and feature extraction which uses one sample image from camera. This suggested method consists of two main parts. One is the environmental-adjustment module which determines optimum sets of filters, filter parameters, and dimensions of features by using "steady state genetic algorithm". The other another part is for face recognition module which performs recognition of face-image using the previous results. In the processing, we used Gabor wavelet for extracting features in the images and k-Nearest Neighbor method for the classification. For testing of the adaptive face recognition method, we tested the adaptive method in the brightness noise, in the impulse noise and in the composite noise and verified that the adaptive method protects face recognition-rate's rapidly decrease which can be occurred generally in the noisy environments.

• Journal of The Korean Society of Agricultural Engineers
• /
• v.63 no.6
• /
• pp.17-26
• /
• 2021

Greenhouses have been damaged due to the uplift pressure from strong wind, for which rebar piles are often installed near the greenhouse to resist the pressure. For the effective design of rebar piles, it is necessary to access the shear strength of soil on which the greenhouse is constructed. This study experimentally evaluates the shear strength of the soil beneath the greenhouse. Four soil samples were collected from four agricultural sites, and prepared for testing with 75, 80, 85, and 90% compaction rates. One-dimensional unconfined compression test (UC), consolidated-undrained triaxial test (CU), and resonant column test (RC) were performed for the evaluation of shear strength and shear modulus. Generally, the higher shear strength and modulus were observed with the higher compaction rates. In particular, the UC shear strength increases with the increase of #200 sieve passing rate. Resulting from the CU test, the sample with the most of coarse soil had the highest friction angle, but the variation is small among samples. Resulting from the CU and RC tests, the ratio of maximum shear modulus with the major principle stress at failure was the higher at the finer soil. The ratio was two to three times greater than the ratio from the standard sand. This indicates that the shear strength is lower for the fine soil than the coarse soil at the same shear modulus. The results of this study will be a useful resource for the estimation of the pull-out strength of the rebar pile against the uplift pressure.

• Archives of Plastic Surgery
• /
• v.46 no.5
• /
• pp.399-404
• /
• 2019

Background The objectives of this study were to design polycaprolactone nanofibers with a radial pattern using a modified electrospinning method and to evaluate the effect of radial nanofiber deposition on mechanical and biological properties compared to non-patterned samples. Methods Radially patterned polycaprolactone nanofibers were prepared with a modified electrospinning method and compared with randomly deposited nanofibers. The surface morphology of samples was observed under scanning electron microscopy (SEM). The tensile properties of nanofibrous mats were measured using a tabletop uniaxial testing machine. Fluorescence-stained human bone marrow stem cells were placed along the perimeter of the radially patterned and randomly deposited. Their migration toward the center was observed on days 1, 4, and 7, and quantitatively measured using ImageJ software. Results Overall, there were no statistically significant differences in mechanical properties between the two types of polycaprolactone nanofibrous mats. SEM images of the obtained samples suggested that the directionality of the nanofibers was toward the central area, regardless of where the nanofibers were located throughout the entire sample. Florescence images showed stronger fluorescence inside the circle in radially aligned nanofibers, with significant differences on days 4 and 7, indicating that migration was quicker along radially aligned nanofibers than along randomly deposited nanofibers. Conclusions In this study, we successfully used modified electrospinning to fabricate radially aligned nanofibers with similar mechanical properties to those of conventional randomly aligned nanofibers. In addition, we observed faster migration along radially aligned nanofibers than along randomly deposited nanofibers. Collectively, the radially aligned nanofibers may have the potential for tissue regeneration in combination with stem cells.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.22 no.1
• /
• pp.338-344
• /
• 2021

In this study, an actual test procedure was considered for the effective operation of a bulletproof test. The problems of the existing system were drawn in two ways. First, it is difficult to mount items of various shapes. Second, various test standards cannot be applied. To improve these problems, an automated and standardized mounting system was designed/applied to mount various items. The multi-purpose mount was compatible with the backing support for body armor testing. The sample holding frame was located inside and was designed to mount samples of various sizes and shapes through vertical movement and fixation without a separate detachment/attachment process. A comparison of the economics before and after the introduction of the item mounting system confirmed the effectiveness of the system by the increased number of daily tests and equipment utilization and reduced hourly cost.

• Journal of Astronomy and Space Sciences
• /
• v.39 no.2
• /
• pp.43-50
• /
• 2022

The unified scheme of Seyfert galaxies hypothesizes that the observed differences between the two categories of Seyfert galaxies, type 1 (Sy1) and type 2 (Sy2) are merely due to the difference in the orientation of the toroidal shape of the obscuring material in the active galactic nuclei. We used in this paper, a sample consisting of 120 Seyfert galaxies at 1.40 × 10⁹ Hz in radio, 2.52 × 10¹⁷ Hz in X-ray and 2.52 × 10²³ Hz in γ-ray luminosities observed by the Fermi Large Area Telescope (Fermi-LAT) in order to test the unified scheme of radio-quiet Seyfert galaxies. Our main results are as follows: (i) We found that the distributions of multiwave luminosities (L_radio, L_X-ray, and L_γ-ray) of Sy1 and Sy2 are completely overlapped with up to a factor of 4. The principal component analysis result reveals that Sy1 and Sy2 also occupy the same parameter spaces, which agrees with the notion that Sy1 and Sy2 are the same class objects. A Kolmogorov-Smirnov test performed on the sub-samples indicates that the null hypothesis (both are from the same population) cannot be rejected with chance probability p ~ 0 and separation distance K = 0.013. This result supports the fact that there is no statistical difference between the properties of Sy1 and Sy2 (ii) We found that the coefficient of the best-fit linear regression equation between the common properties of Sy1 and Sy2 is significant (r > 0.50) which plausibly implies that Sy1 and Sy2 are the same type of objects observed at different viewing angle.

• Journal of Korean Society of Occupational and Environmental Hygiene
• /
• v.31 no.1
• /
• pp.22-30
• /
• 2021

Objectives: The objectives of this study were to develop a quality control protocol of inorganic acids using ion chromatograph and to evaluate analytical proficiency of the legally designated agencies. Methods: This study prepared inorganic acid samples by injecting three anion certified solutions (chloride, nitrate, and sulfate) on the quartz filters. To investigate the storage stability and concentration consistency of the samples, 240 samples for each anion were tested at weeks 0, 2, 4, 8, 12, and 16 while storing at 4℃ and 25℃. To evaluate analytical proficiency, two separate testings were administrated for six skilled analysts and 46 analysts affiliated with legally designated agencies. Results: Average recoveries of the three ions after 16 weeks of storage were fairly high (over 95%). In addition, average recoveries (chloride = 97%, nitrate = 96%, and sulfate = 103%) after 16 weeks of storage at low temperate were relatively higher than those (94%, 93%, and 98%) at room temperature. The coefficients of variation (CV) for the three ions were less than 5% except for the sulfate sample at 5.56 ㎍ (CV = 12.4%). The average ratios of the concentration values analyzed by the legally designated agencies to the injected concentrations were close to 1. However, their CVs were relatively greater (chloride ≤ 49%, nitrate ≤ 14%, and sulfate ≤ 28%), which implies a need for quality control. Conclusions: The quality control protocol used in this study for the three inorganic acids can be utilized in the quality control for ion chromatography.

• Biomedical Science Letters
• /
• v.29 no.2
• /
• pp.81-87
• /
• 2023

Pan-Enterovirus (Pan-EV) infects millions of children and infants worldwide every year. As severe infections have recently been reported, the need for monitoring has consequently intensified. Pan-EV is a categorical name for waterborne enteroviruses belonging to the Picornaviridae family, and includes a wide range of pathogens including Coxsackievirus (CoxV), Echovirus (EcoV) and Enterovirus (EV). In this study, we proposed an optimal RT-nested PCR method for diagnosis of various types of Pan-EV in an aquatic environment and developed a positive control. Considering detection sensitivity, specific reaction, and final identification, one condition capable of amplifying 478 bp among the four candidates in the 1^st round PCR (RT-PCR) and one condition in the 2^nd round PCR (nested PCR) were selected. Through the detection of nucleic acids extracted from 123 groundwater samples and the detection sensitivity test based on artificial spiking in the sample, the methods are optimal for non-disinfected water samples such as groundwater. We developed a positive control for Pan-EV detection that can be amplified to different sizes under the two conditions. Accuracy could be further improved by testing for contamination from the control group. The method proposed in this study and the positive control developed are expected to be used in monitoring Pan-EV in aquatic environments including groundwater through future research using more samples.

• Safety and Health at Work
• /
• v.15 no.1
• /
• pp.80-86
• /
• 2024

Background: The Work Ability Index (WAI) is an instrument that measures work ability. The wide dispersion of the WAI internationally has led to its adaptation for use in different countries. This study aimed to evaluate the psychometric properties of the Spanish version of the WAI. Methods: A methodological design was used over an opportunistic sample of 233 workers in the aeronautical industry in Spain. Reliability was evaluated through internal consistency. Factorial validity, known groups, and convergent validity were tested. Results: The Cronbach's alpha and item-total correlation indicated an adequate internal consistency. The confirmatory factor analysis, performed to evaluate the factorial validity, found adequate fit indices for a two-factor solution with a high correlation between the factors. Factor 1, "Subjectively estimated work ability and resources", was composed of 3 subscales and factor 2, "Ill-health-related", of 2 subscales. Subscales 4 and 6 had loading in both factors. Workers under 45 years of age obtained higher significant scores than older ones. Convergent validity was also evidenced since WAI was highly correlated with self-assessment of health status. Conclusions: The Spanish version of the WAI has shown evidence of reliability and validity in this study, supporting its use in individual and collective health surveillance by occupational health professionals. The factorial solution that was found has previously been reported in another international context. However, further research is needed to resolve the discrepancies detected in the role of some subscales between other national and international studies.

• Journal of the Korea Institute of Building Construction
• /
• v.24 no.3
• /
• pp.285-295
• /
• 2024

This study investigated the impact of accelerated carbonation on Ordinary Portland Cement(OPC) paste that had undergone steam curing at 500℃·hr. Two carbonation environments were examined: atmospheric carbonation(1atm, 20% CO₂) and pressurized carbonation(5atm, 99% CO₂). Chemical analysis using X-ray diffraction(XRD) and Fourier-Transform Infrared spectroscopy(FT-IR) were conducted, along with physical characterization via scanning electron microscopy(SEM) and compressive strength testing. Results indicated that atmospheric carbonation with 20% CO₂ concentration significantly densified the internal microstructure of the OPC paste, leading to enhanced compressive strength. Conversely, pressurized carbonation at 5atm with 99% CO₂ concentration resulted in rapid densification of the surface structure, which hindered CO₂ diffusion into the sample. This limited the extent of carbonation and prevented the improvement of physical properties.