• Title/Summary/Keyword: two sample testing

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A Bayesian Multiple Testing of Detecting Differentially Expressed Genes in Two-sample Comparison Problem

  • Oh Hyun-Sook;Yang Wan-Youn
    • Communications for Statistical Applications and Methods
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    • v.13 no.1
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    • pp.39-47
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    • 2006
  • The Bayesian approach to multiple testing procedure for one sample testing problem proposed by Scott and Berger (2003) is extended to two-sample comparison problem in microarray experiments. The prior distribution of each gene's mean for one sample is given conditionally on the corresponding gene's mean for the other sample. Posterior distributions of interesting parameters are derived and estimated based on an importance sampling method. A simulated example is given for illustration.

Analysis of a Queueing Model with a Two-stage Group-testing Policy (이단계 그룹검사를 갖는 대기행렬모형의 분석)

  • Won Seok Yang
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.45 no.4
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    • pp.53-60
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    • 2022
  • In a group-testing method, instead of testing a sample, for example, blood individually, a batch of samples are pooled and tested simultaneously. If the pooled test is positive (or defective), each sample is tested individually. However, if negative (or good), the test is terminated at one pooled test because all samples in the batch are negative. This paper considers a queueing system with a two-stage group-testing policy. Samples arrive at the system according to a Poisson process. The system has a single server which starts a two-stage group test in a batch whenever the number of samples in the system reaches exactly a predetermined size. In the first stage, samples are pooled and tested simultaneously. If the pooled test is negative, the test is terminated. However, if positive, the samples are divided into two equally sized subgroups and each subgroup is applied to a group test in the second stage, respectively. The server performs pooled tests and individual tests sequentially. The testing time of a sample and a batch follow general distributions, respectively. In this paper, we derive the steady-state probability generating function of the system size at an arbitrary time, applying a bulk queuing model. In addition, we present queuing performance metrics such as the offered load, output rate, allowable input rate, and mean waiting time. In numerical examples with various prevalence rates, we show that the second-stage group-testing system can be more efficient than a one-stage group-testing system or an individual-testing system in terms of the allowable input rates and the waiting time. The two-stage group-testing system considered in this paper is very simple, so it is expected to be applicable in the field of COVID-19.

Large Sample Test for Independence in the Bivariate Pareto Model with Censored Data

  • Cho, Jang-Sik;Lee, Jea-Man;Lee, Woo-Dong
    • Journal of the Korean Data and Information Science Society
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    • v.14 no.2
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    • pp.377-383
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    • 2003
  • In this paper, we consider two components system in which the lifetimes follow the bivariate Pareto model with random censored data. We assume that the censoring time is independent of the lifetimes of the two components. We develop large sample tests for testing independence between two components. Also we present simulated study which is the test based on asymptotic normal distribution in testing independence.

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MINITAB Macros for Testing the Difference of Mean Vectors of Two Multivariate Populations

  • Hyuk Joo;Min Ah
    • Communications for Statistical Applications and Methods
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    • v.7 no.1
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    • pp.179-198
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    • 2000
  • We consider the problem of comparing the mean vectors of two multivaiate populations, We focus on testing hypotheses concerning two multivariate mean vectors by use of MINITAB, For the cases of small sample and large sample MINITAB programs and outputs are presented for solving staistical problems. The MiniTAB programs made in this paper are saved as macro files and thus can be conveniently used for solving another problems.

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ON TESTING THE EQUALITY OF THE COEFFICIENTS OF VARIATION IN TWO INVERSE GAUSSIAN POPULATIONS

  • Choi, Byung-Jin;Kim, Kee-Young
    • Journal of the Korean Statistical Society
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    • v.32 no.2
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    • pp.93-101
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    • 2003
  • This paper deals with testing the equality of the coefficients of variation in two inverse Gaussian populations. The likelihood ratio, Lagrange-multiplier and Wald tests are presented. Monte-Carlo simulations are performed to compare the powers of these tests. In a simulation study, the likelihood ratio test appears to be consistently more powerful than the Lagrange-multiplier and Wald tests when sample size is small. The powers of all the tests tend to be similar when sample size increases.

Large Sample Tests for Independence in Bivariate Pareto Model with Censored Data

  • Cho, Jang-Sik;Lee, Jea-Man;Lee, Woo-Dong
    • 한국데이터정보과학회:학술대회논문집
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    • 2003.05a
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    • pp.121-126
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    • 2003
  • In this paper, we consider two-components system which the lifetimes follow bivariate pareto model with censored data. We develop large sample tests for testing independence between two-components. Also we present simulated study which is the test based on asymptotic normal distribution in testing independence.

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A Bayes Criterion for Testing Homogeneity of Two Multivariate Normal Covariances

  • Kim, Hea-Jung
    • Journal of the Korean Statistical Society
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    • v.27 no.1
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    • pp.11-23
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    • 1998
  • A Bayes criterion for testing the equality of covariance matrices of two multivariate normal distributions is proposed and studied. Development of the criterion invloves calculation of Bayes factor using the imaginary sample method introduced by Spiegelhalter and Smith (1982). The criterion is designed to develop a Bayesian test criterion, so that it provides an alternative test criterion to those based upon asymptotic sampling theory (such as Box's M test criterion). For the constructed criterion, numerical studies demonstrate routine application and give comparisons with the traditional test criteria.

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A Two Sample Test for Functional Data

  • Lee, Jong Soo;Cox, Dennis D.;Follen, Michele
    • Communications for Statistical Applications and Methods
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    • v.22 no.2
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    • pp.121-135
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    • 2015
  • We consider testing equality of mean functions from two samples of functional data. A novel test based on the adaptive Neyman methodology applied to the Hotelling's T-squared statistic is proposed. Under the enlarged null hypothesis that the distributions of the two populations are the same, randomization methods are proposed to find a null distribution which gives accurate significance levels. An extensive simulation study is presented which shows that the proposed test works very well in comparison with several other methods under a variety of alternatives and is one of the best methods for all alternatives, whereas the other methods all show weak power at some alternatives. An application to a real-world data set demonstrates the applicability of the method.

Probability of Rejection Curve for Equivalence Testing Procedure

  • Sung, Nae Kyung
    • Journal of Korean Society for Quality Management
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    • v.22 no.4
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    • pp.102-110
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    • 1994
  • We investigate the small-sample behavior of the probability of rejection curves and its performance for a equivalence testing procedure based on confidence intervals which was developed with a motivation from bioequivalence studies. This type of equivalence studies are conducted frequently in pharmaceutical industries to compare the relative bioavailabilty of two formulations of a drug and can be applied various fields where assurance of quality equivalence is needed. From the Monte-Carlo simulation results we suggest proper sample sizes for the equivalence testing procedure.

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Influence in Testing the Equality of Two Covariance Matrices (두개의 공분산 행렬의 동질성 검정에서의 영향치 분석)

  • Myung Geun Kim
    • The Korean Journal of Applied Statistics
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    • v.7 no.2
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    • pp.213-224
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    • 1994
  • A diagnostic method useful for detecting outliers in testing the equality of two covariance metrics is developed using the influence curve approach. This method is easily generalized to more than two covariance matrices. A sample version for the influence measure of detecting outliers is considered based on the empirical distribution functions. The sample version includes as its component terms the well-known test statistic for detecting one outlier at a time introduced by Wilks and its generalization to the two-group case.

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