• Clinical and Experimental Pediatrics
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• v.64 no.5
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• pp.239-246
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• 2021

Background: The consequences of severe acute respiratory syndrome corona virus 2 on mother and fetus remain unknown due to a lack of robust evidence from prospective studies. Purpose: This study evaluated the effect of coronavirus disease 2019 (COVID-19) on neonatal outcomes and the scope of vertical transmission. Methods: This ambispective observational study enrolled pregnant women with COVID-19 in North India from April 1 to August 31, 2020 to evaluate neonatal outcomes and the risk of vertical transmission. Results: A total of 44 neonates born to 41 COVID-19-positive mothers were evaluated. Among them, 28 patients (68.3%) (2 sets of twins) were delivered within 7 days of testing positive for COVID-19, 23 patients (56%) (2 sets of twins) were delivered by cesarean section; 13 newborns (29.5%) had low birth weight; 7 (15.9%) were preterm; and 6 (13.6%) required neonatal intensive care unit admission, reflecting an increased incidence of cesarean delivery and low birth weight but zero neonatal mortality. Samples of cord blood, placental membrane, vaginal fluid, amniotic fluid, peritoneal fluid (in case of cesarean section), and breast milk for COVID-19 reverse transcription-polymerase chain reaction tested negative in 22 prospective delivery cases. Nasopharyngeal swabs of 2 newborns tested positive for COVID-19: one at 24 hours and the other on day 4 of life. In the former case, biological samples were not collected as the mother was asymptomatic and her COVID-19 report was available postdelivery; hence, the source of infection remained inconclusive. In the latter case, all samples tested negative, ruling out the possibility of vertical transmission. All neonates remained asymptomatic on follow-up. Conclusion: COVID-19 does not have direct adverse effects on the fetus per se. The possibility of vertical transmission is almost negligible, although results from larger trials are required to confirm our findings.

• Korean Journal of Metals and Materials
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• v.47 no.12
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• pp.797-810
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• 2009

A study was made of the effects of a Sn addition on the microstructure and microfracture mechanism of squeeze cast AZ51-xSn magnesium alloys. Microstructural observation, in situ fracture testing, and fractographic observations were conducted on these alloys to clarify the microfracture process. The microstructural analyses indicated that $Mg_2Sn$ particles as well as $Mg_{17}Al_{12}$ particles precipitated mainly along the solidification cell boundaries; the volume fraction of these hard particles increased as the amount of added Sn increased, with increased the strength. From in situ fracture observations of the AZ51-7Sn alloy, coarse precipitates located on the cell boundaries worked as easy crack propagation sites and caused abrupt intercellular fracturing. On the other hand, the overall fracture properties of the AZ51-3Sn alloy improved because crack propagation proceeded into the Mg matrix rather than into the cell boundaries as twins developed actively, as confirmed by an R-curve analysis. These findings suggest that the addition of 3~5 wt.% Sn is effective in improving both the tensile and fracture properties on the basis of well-developed twins, the blocking of crack propagation, and crack blunting.

• Journal of Industrial Convergence
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• v.19 no.1
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• pp.65-70
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• 2021

This study aims to propose specific directions for developing digital twin contents. This aim is achieved by thorough literature review and applying the grounded theory. Based on customers' need analysis, this study suggests the priorities of contents development of digital twins. As a result, complex workflows and dangerous training contents are adequate to be developed. Moreover, large-scale projects such as nuclear powerplants that are hard to build the mock-ups were considered to be effective. This study provides significant information for not only software developers but also clients who desire to reduce training fees and improve the complex workflows. Since these client companies operate based upon multiple complex workflows, this study encourages stakeholders to make effective decisions. This research needs further analysis of current digital twin technology- possibilities and limitations.

• Journal of KIBIM
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• v.11 no.4
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• pp.31-41
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• 2021

Digital twins between "BIM Digital Model-Physical Prototype Model" will be built for Noise Barrier tunnel(NBT) that meet the definition of N.G smart city facilities derived from previous studies to build a data flow that connects data at each stage of design, construction, and operation. In this process, BIM design automation tools are created and utilized, and consistent transmission of member and attribute data is performed by converting them into IFC format. Through this, the purpose is to improve the labor-intensive environment required from the design stage of the NBT and to consistently maintain the information required for subsequent production and construction. This includes achieving changes in the construction industry based on digital transformation by unifying various data formats used differently for each industry from design to operation. In addition, it demonstrates that information exchange in the maintenance and management stages is possible based on the data exchange of the established digital twin and aims to improve the existing labor-intensive environment and expand operability between digital and physical information. As suggested in previous studies, the implementation of digital twins in these N.G smart city facilities includes the possibility of building an environment that adds to the possibility of high value-added product platforms as well as the function of big data platforms targeting existing smart cities.

• The Journal of the Korea Contents Association
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• v.21 no.7
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• pp.248-258
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• 2021

24-hour monitoring is required to maintain the city's lifeline function in the underground facility for public utilities. And it is necessary to develop technology to exchange the shortage of human resources. It is difficult to reflect the specificity of underground space management in general management methods. This study proposes underground facility for public utilities digital twin system requirements. The concept of space is divided into physical space and virtual space, and the physical space constitutes the type and layout of the sensor that is the basis for the construction of the multimodal image sensor system, and the virtual space constitutes the system architecture. It also suggested system functions according to the task. It will be effective in preventing disasters and maintaining the lifeline function of the city through the digital twins.

• Journal of the korean academy of Pediatric Dentistry
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• v.49 no.2
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• pp.234-240
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• 2022

Floating-Harbor syndrome (FHS) is a rare genetic disorder. This report introduced in a patient with FHS. Distinctive facial characteristics, severe skeletal class 3 malocclusion with underdeveloped maxilla and protruded mandible, congenital missing teeth, microdontia and ectopic positions of maxillary teeth were presented in the patient. In his twin sister, mild skeletal class 3 malocclusion with protruded mandible was observed but congenital missing teeth and microdontia were not observed. High-arched palate, narrow V-shaped maxillary arch compared to wide and ovoid mandibular arch and inverse relationship between the maxillary and mandibular intermolar width resulted in posterior crossbite were confirmed by model analysis of the patient. These were not observed in the twins. Behaviorally, poor cooperation during dental treatment because of mental retardation was observed in the patient.

• Journal of Advanced Navigation Technology
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• v.27 no.4
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• pp.473-480
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• 2023

This study evaluated a novel method of defining the automatic flight path of unmanned aerial vehicles (UAVs) for search and rescue missions in a VR environment. The developed VR content reserves miniature digital twins of a building in the fire and a steep mountain terrain site. The users drow the UAV's scanning path using hand gestures on the surface of digital twins, and then the UAV make an automatic flight along the defined path. According to human-in-the-loop simulation tests comparing the novel method with a conventional manual flight task with 19 participants, the novel method did not improve the mission performance but participants felt a lower mental workload. The designer may need to consider the automation support on the vulnerable points of the SAR mission environment while maintaining experts' mapping capability.

• Earthquakes and Structures
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• v.22 no.5
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• pp.503-515
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• 2022

This paper presents the development of seismic fragility curves for a precast reinforced concrete bridge instrumented with a structural health monitoring (SHM) system. The bridge is located near an active seismic fault in the Dominican Republic (DR) and provides the only access to several local communities in the aftermath of a potential damaging earthquake; moreover, the sample bridge was designed with outdated building codes and uses structural detailing not adequate for structures in seismic regions. The bridge was instrumented with an SHM system to extract information about its state of structural integrity and estimate its seismic performance. The data obtained from the SHM system is integrated with structural models to develop a set of fragility curves to be used as a quantitative measure of the expected damage; the fragility curves provide an estimate of the probability that the structure will exceed different damage limit states as a function of an earthquake intensity measure. To obtain the fragility curves a digital twin of the bridge is developed combining a computational finite element model and the information extracted from the SHM system. The digital twin is used as a response prediction tool that minimizes modeling uncertainty, significantly improving the predicting capability of the model and the accuracy of the fragility curves. The digital twin was used to perform a nonlinear incremental dynamic analysis (IDA) with selected ground motions that are consistent with the seismic fault and site characteristics. The fragility curves show that for the maximum expected acceleration (with a 2% probability of exceedance in 50 years) the structure has a 62% probability of undergoing extensive damage. This is the first study presenting fragility curves for civil infrastructure in the DR and the proposed methodology can be extended to other structures to support disaster mitigation and post-disaster decision-making strategies.

• International conference on construction engineering and project management
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• 2022.06a
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• pp.408-417
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• 2022

Although traditionally perceived as being a visualization and asset management resource, the relatively rapid rate of improvement of computing power, coupled with the proliferation of cloud and edge computing and the IoT has seen the expanded functionality of modern Digital Twins (DTs). These technologies, when applied to buildings, are now providing users with the ability to analyse and predict their energy consumption, implement building controls and identify faults quickly and efficiently, while preserving acceptable comfort and well-being levels. Furthermore, when these building DTs are linked together to form a community DT, entirely new and novel energy management techniques, such as demand side management, demand response, flexibility and local energy markets can be unlocked and analysed in detail, creating circularity in the economy and making ordinary building occupants active participants in the energy market. Through the EU Horizon 2020 funded TwinERGY project, three different levels of DT (consumer - building - community) are being created to support the creation of local energy markets while optimising building performance for real-time occupant preferences and requirements for their building and community. The aim of this research work is to demonstrate the development of this new, interrelated, multi-level DT that can be used as a decision-making tool, helping to determine optimal scenarios simultaneously at consumer, building and community level, while enhancing and successfully supporting the community's management plan implementation.

• Asian-Australasian Journal of Animal Sciences
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• v.18 no.2
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• pp.151-157
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• 2005

Sheep production is affected by genetic and non-genetic factors. A knowledge of these factors is essential for efficient management and for the accurate estimation of breeding values. The objective of this study was to establish the non-genetic factors which affect birth weight and weaning weight in Dorper, Mutton Merino and indigenous Sabi sheep breeds. A total of 2,625 birth and weaning weight records from Grasslands Research Station collected from 1991 through 1993, were used. The records were collected from indigenous Sabi (939), Dorper (807) and Mutton Merino (898) sheep. A mixed classification model containing the fixed effects of year, birth status and sex was used for identification of non-genetic factors. Sire within breed was included as a random effect. Two factor interactions and three factor interactions were important in indigenous Sabi, Mutton Merino and Dorper sheep. The mean birth weights were 4.37${\pm}$0.04 kg, 4.62${\pm}$0.04 kg and 3.29${\pm}$0.04 kg for Mutton Merino, Dorper and Sabi sheep, respectively. Sire had significant effects (p<0.05) on birth weight in Mutton Merino and indigenous Sabi sheep. Year of lambing had significant effects (p<0.05) on birth weight in indigenous Sabi, Mutton Merino and Dorper sheep. The effect of birth status was non significant in Dorper and Mutton Merino sheep while effect of birth status was significant on birth weight in indigenous Sabi sheep. In Indigenous Sabi sheep lambs born as singles (3.30${\pm}$0.05 kg) were 0.23 kg heavier than twins (3.07${\pm}$0.05 kg), in Mutton Merino lambs born as singles (3.99${\pm}$0.08 kg) were 0.07 kg heavier than twins (3.92${\pm}$0.08 kg) and in Dorper lambs born as singles (4.41${\pm}$0.04 kg) were 0.02 kg heavier than twins (4.39${\pm}$0.04 kg). On average males were heavier than females (p<0.05) weighing (3.32${\pm}$0.04 kg vs. 3.05${\pm}$0.07 kg) in indigenous Sabi, 4.73${\pm}$0.03 kg vs. 4.08${\pm}$0.05 in Dorper and 4.26${\pm}$0.07 kg vs. 3.66${\pm}$0.09 kg in Mutton Merino sheep. Two way factor interactions of sire*year, year*sex and sex*birth status had significant effects (p<0.05) on birth weight in indigenous Sabi, Mutton Merino and Dorper sheep while the effect of year*birth status was non significant on birth weight in Indigenous Sabi sheep. The three way factor interaction of year*sex*birth status had a significant effect (p<0.01) on birth weight in indigenous Sabi and Mutton Merino. Tupping weight fitted as a covariate had significant effects (p<0.001) on birth weight in indigenous Sabi, Mutton Merino and Dorper sheep. The mean weaning weights were 17.94${\pm}$0.31 kg, 18.19${\pm}$0.28 kg and 14.39${\pm}$0.28 kg for Mutton Merino, Dorper and Indigenous Sabi sheep, respectively. Effects of sire and sire*year were non significant on weaning weight in Dorper and Mutton Merino while year, sex and sex*year interaction had significant effects (p<0.001) on weaning weight. On average males were heavier than females (p<0.001) at weaning. The respective weaning weights were 18.05${\pm}$0.46 kg, 18.68${\pm}$0.19 kg, 14.14${\pm}$0.15 kg for males and 16.64${\pm}$0.60 kg, 16.41${\pm}$0.31 kg, 12.64${\pm}$0.32 kg for females in Mutton Merino, Dorper and Indigenous Sabi sheep. Lambs born as singles were significantly heavier at weaning than twins, 0.05 kg, 0.06 kg and 0.78 kg for Mutton Merino, Dorper and Indigenous Sabi sheep, respectively. Effect of tupping weight was highly significant on weaning weight. The three way factor interaction year*sex*birth status had a significant effect (p<0.01) on weaning weight. Correction for environmental effects is necessary to increase accuracy of direct selection for birth weight and weaning weight.