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Systemic Review of Hyaluronate for the Treatment of Osteoarthritis (골관절염 치료제 히알우론산 임상연구결과의 Systemic Review)

  • Bang, Joon-Seok
    • Korean Journal of Clinical Pharmacy
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    • v.17 no.1
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    • pp.38-45
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    • 2007
  • Background: The multitude of the therapeutic usefulness of intra-articular injection of hyaluronate on oateoarthritis of the knee is still in question. The objective of this systemic review was to elucidate both the therapeutic efficacy and the safety of intra-articular administration of hyaluronic acid for degenerative osteoarthritis of the knee joints. Methods: I searched MEDLINE and Korea Medical Database (KMbase) from January 1990 to April 2007 using a combination search terms for knee osteoarthritis and hyaluronic acid and a filter for randomized controlled trials. I extracted data on pain at rest, and during or just after movement, on joint function, and on adverse events. Results: Ten trials that reported usable quantitative information on any of the predefined end points were identified and included in the systemic review. Intra-articular injection of hyaluronic acid can decrease symptoms of osteoarthritis of the knee. The study revealed significant improvements in pain and functional outcomes with few adverse effects. However, there was significant between-study heterogeneity in the estimates of the efficacy of hyaluronic acid. Sub-group analysis showed that lower methodological quality such as a single-blind or single-center design resulted in higher estimates hyaluronic acid efficacy, and that patients older than sixty years of age and those with the most advanced radiographic stage of osteoarthritis were less likely to benefit from intra-articular injection of hyaluronic acid. Conclusion: According to the currently available evidence, intra-articular hyaluronic acid has been proven clinically effective for the patients bearing the knee osteoarthritis with NSAID-induced GI troubles or inapplicable to any surgery, and may be associated with lower risk of adverse events.

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A Study on Research & Development and Quality Stability of Functional Red Pepper Dressing (기능성 고추드레싱의 개발 및 품질 안정성에 관한 연구)

  • 손무호
    • Culinary science and hospitality research
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    • v.10 no.2
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    • pp.107-120
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    • 2004
  • In recently, foods must to be contained a health point and fashionable feeling, mayonnaise was called pronoun of dressing must be changes to new products. At this point, new type's dressing oil was research and developing used for raw- materials of 13 kinds. Red pepper seasoning oil, seasoning soy sauce, seasoning solution and seasoning oil were manufactured from soy sauce, vinegar, garlic etc. Manufacturing of new type's dressing oil(DO) could from only blending of these seasoning raw-materials. The result of organoleptic test about vegetables, pizzas and meats was esquired a distinction. According to, it was treated to addition of a functional raw-materials. In this study, it was investigated red pepper DO and DO for diabetic, adult disease patient as well as DO for children, Japanese dining room, general man etc. But these DO products had trouble to layer separation of upper layer and bottom layer, this problem was happened to shaking. This troubles were able to treat gums and emulsifiers.

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Korean Translation and Validation of the Paediatric Allergic Disease Quality of Life Questionnaire (PADQLQ) (Paediatric Allergic Disease Quality of Life Questionnaire (PADQLQ)의 한국어판 개발과 신뢰도, 타당도에 대한 연구)

  • Park, Seul Ki;Kim, Sehyun;Lee, Sun Haeng;Chang, Gyu Tae
    • The Journal of Pediatrics of Korean Medicine
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    • v.27 no.3
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    • pp.41-52
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    • 2013
  • Objectives In pediatrics of Korean Medicine, it is crucial to evaluate the overall symptoms of children, especially in the children who have serious troubles in their life. In the era when diagnosis in Korean Medicine is quite suitable to evaluate multiple allergic diseases, and when growing numbers are in needs, development of an objective measurement scale for diagnosis of allergic disease in Korean Medicine became essential. Therefore, in the study, pediatric Allergic Disease Quality of Life Questionnaire (PADQLQ) was translated into Korean version with validations on some aspects. Methods In this study, we translated and validated the PADQLQ and established psychometric evidence on its utility in Korean children with similar problems. 71 children, age of 6 ~ 18 with allergic disease has participated. Results The internal consistency reliability of the PADQLQ by Cronbach's ${\alpha}$ was 0.94. In three domains (Practical, Physical, Emotional), the Cronbach's ${\alpha}$ was 0.77, 0.90 and 0.69. The Spearman's rank correlation coefficient between PADQLQ total score and VAS was 0.75 (p<0.001). And, Structural validity was evaluated by the ANOVA test. QoL differences of the four groups in the three domains (practical, physical, emotional) were significant. The item discriminative indices were ranged from 0.1651 to 0.8188. Conclusions Korean version PADQLQ is highly reliable and valid for children with allergic diseases. This is significant to assess the relative seriousness of the allergic diseases and to evaluate the efficacy of different treatments in Korean Medicine.

A case of Diphyllobothrium latum infection with a brief review of diphyllobothriasis in the Republic of Korea

  • Lee, Eun-Bin;Song, Jung-Hoon;Park, Nam-Seon;Kang, Byung-Kook;Lee, Hyung-Suk;Han, Yoon-Ju;Kim, Hyo-Jin;Shin, Eun-Hee;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.45 no.3
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    • pp.219-223
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    • 2007
  • A case of Diphyllobothrium latum infection in a 49-year old man is described, and diphyllobothriasis latum in the Republic of Korea is briefly reviewed. An incomplete strobila of a tapeworm, 95 cm in length, without scolex and neck, was spontaneously discharged in the feces of a patient. On the basis of morphologic characteristics of the worm and eggs, the worm was identified as D. latum. The patient was successfully treated with a single dose (15 mg/kg) of praziquantel. The most probable source of infection was salmon flesh according to the past history of the patient. The first case of D. latum infection was documented in 1971, and this is the 43rd recorded case in the Republic of Korea. The 43 cases were briefly reviewed. The patients' main complaints were gastrointestinal troubles, such as mild abdominal pain, indigestion, and diarrhea, and discharge of tapeworm segments in the feces. The suspected infection sources included raw or improperly cooked flesh of fresh or brackish water fish, including the perch, mullet, salmon, and trout.

Electronic Shielding Effectiveness of the Structure with Long-shape Aperture (Long-shape aperture를 갖는 구조물의 Electronic Shielding Effectiveness 연구)

  • Heo, Yu;Kim, Min-Ho;Kim, In-Seok;Baek, Young-Nam
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.810-813
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    • 2003
  • Wide spread using of mobile and handy electronic apparatus is giving rise to a question on the harmfulness of health and causing troubles when electical and electronic equipments are in use. This paper reports on the experimental results obtained by using a pliable and structured specimen that has a long shape aperture, made of stainless steel fibers. Based on the TEM mode transfer structure that was designed and manufactured through HFSS, we measured electromagnetic shielding effectives, where the network analyzer was applied. We could draw a conclusion from this research that the metal fabric showed a good electromagnetic shielding effect, mainly by means of the good reflex loss at the fiber surface. Even though the material itself possesses a good absorption loss. the specimen revealed that structural factors. e.g.. the shape of the aperture. the size of the aperture, etc., can have a more influence on the shielding effect than the components of material have. A special notice is required for modeling and analyzing the electromagnetic characteristics of metal fabrics, because there exists a strong possibility that multiple reflection can happen on the surface of metal fibers. which can presume a model of fiber bundle and fabric structure.

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A Study on the GMA-based CIM Design for u-City Service Implementation (u-City 서비스 구현을 위한 GMA 기반의 CIM 설계에 관한 연구)

  • Ock, Young-Seok;Ahn, Chang-Won;Kim, Min-Soo
    • The Journal of Society for e-Business Studies
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    • v.14 no.4
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    • pp.287-297
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    • 2009
  • Though the interest for the construction of ubiquitous city (u-City) has been increased in many researches, many of those efforts are still done somewhat separated ways such as from the perspective of architectural design of urban city or from the perspective of underlying ICT (Information and Communication Technology) implementation. Since there are various services and technical components involved in u-City implementation, those separated approaches can cause much troubles while implementing u-City. In addition to this, because u-City components are continually changing and expanding, to cope with this evolution, many researches about the infrastructure of u-City should be done in a systematic way while integrally considering various perspectives of u-City. In this research, by combining WBEM/CIM standards to GMA (Grid Monitoring Architecture), we could provide WBEM/CIM design that is usable for u-City implementation. In contrast to the conventional research that is still abstract, our study presents concrete and implementable u-City infrastructure model. We hope our result will be a valuable reference for the other u-City infrastructure-related researches.

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A Study on Improvement Strategies According to the Inconvenience Due to Female Cancer Wearing Alopecia Wigs (여성 암환우들의 탈모용 가발 착용 시 불편에 따른 개선방안 연구)

  • Jin, Soon-Ho;Kim, Young-Bae;Park, Jang-Soon
    • Journal of Digital Convergence
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    • v.15 no.8
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    • pp.417-422
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    • 2017
  • This study conducted frequency analysis for male and female patients aged 60 and over from the results of analyzing improvement strategies for inconvenience due to wearing alopecia wigs. When the patoent started perceive their depilatory diseases was right after treatment of anticancer drugs or radiotherapy, and they were found to suffer from inconveniences of being dried, etc. After treatment of chemotherapy, as for the falling-out parts, eyebrows were found to be the highest 52.1%, and pubic hair 38%, axilla hair 29% in that order. And the inconvenience level of wearing wigs among the patients with the different background of education indicates that the professions of the patients affect the ease of use. It is presumed that the easiness in use which the college graduates, high school graduates, and postgraduates showed is attributable to the age difference. to improve the inconveniences from cancer patients wearing wigs, scape troubles and close adhesion are constantly needed.

Study on the Couple Relationships in Military : Relationship among Military life Stress, Couple Relationship Resilience and Military Adjustment (육군 병사들의 커플관계에 관한 연구 : 군 생활 스트레스, 커플관계 탄력성, 그리고 군 생활 적응의 관계)

  • Jeon, Ji-Kyung
    • Journal of Digital Convergence
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    • v.16 no.2
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    • pp.47-56
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    • 2018
  • The purpose of this study was to identify the relation among the CRR, MA, and MS of military solder's who have experienced couple relationship troubles. Data collected from 239 soldiers in front-line division and post line division was analyzed by correlation analysis, t-test and hierarchical analysis using SPSS 18.0. As the results, 1. CRR and MA showed a positive correlation and CRR and MS showed a negative corelation. 2. CRR showed a significant influence on the MA. 3. CRR had a mediating effects on the process where MS influenced MA. The results of this study are expected to be used as the primary data for raising the adaptability to the military especially on the subject of couple relationship, and as an educational guidance for helping soldiers to see the positive aspect of the adversity and stress of military life.

Experimental studies on stabilization techniques for ground over abandoned subsurface excavations

  • Pal Samir K.
    • 한국지구물리탐사학회:학술대회논문집
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    • 2003.11a
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    • pp.142-149
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    • 2003
  • Blind hydraulic backfilling is a commonly used technique for subsidence control of the strata over unapproachable waterlogged underground excavations. In this investigation model studies on all the three variants of this technique, namely, hydro-pneumatic or air-assisted gravity backfilling, pumped-slurry backfilling and simple gravity backfilling, have been carried out in fully transparent models of the underground excavations. On examination of the filling process, it was revealed that in all the three cases, the basic process of filling occurs by sand transport along one or more meandering channels. The relative influence of sand, water and air flow rates on the area of filling from a single inlet point and the hydraulic pressure loss per unit length were studied in details. In hydro-pneumatic backfilling process, the air bubbles while moving upward through the meandering channels provide an additional buoyant force over and above the available hydraulic head. In this way the area of filling from a single borehole may be quite large even at small flow rates of water. During actual field implementation the injected air, if not released completely from the rise side holes, may cause troubles by way of creating potholes on the surface. The pumped-slurry technique has shown its capability of filling a relatively larger area at faster rate, especially when high-volume, low-pressure method was selected. But simple gravity filling was also found to be equally effective method as slurry pumping, especially when flow rates were high. In the second and third method discussed above, examination of variations of injection pressure was also done and its relation with physical phenomenon was also attempted. Some empirical relationships were also developed using multivariate regression with a view to help the practicing engineers.

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A Therapeutic Case Report of Serious Musculoskeletal Systemic Pains of the Menopausal Disorder Studied in Connection with the Life Event Stress (갱년기 장애의 심한 근골격계 통증을 생활사건 스트레스와 연관지어 고찰한 치험1례)

  • Jung, Sun-Hyung;Lee, Jin-Moo;Lee, Chang-Hoon;Cho, Jung-Hoon;Jang, Jun-Bock;Lee, Kyung-Sub
    • The Journal of Korean Obstetrics and Gynecology
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    • v.21 no.2
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    • pp.252-262
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    • 2008
  • Purpose: This paper is aim to report that menopausal disorder can be effectively diagnosed and treated by referring to the life event stress of patient. Methods: Researchers got a grip on the life event stress of patient by using medical examinations by interview and compared the conditions of patient before and after treatment by using Kupperman's Index. The prescription of the Gamidangguisu-san hap samhap-tang( Jiaweidangguixu-san he sanhetang) and the Gamisoyo-san (Jiaweixiaoyao-san) and the acupuncture therapy and the moxibustion therapy were used for the treatment. Results: The serious musculoskeletal systemic pains, which includes back pain, lumbago, and myalgia, and other menopausal troubles were improved remarkably. Conclusion: The menopausal disorder could be caused by not only the change of hormone but also complex factors of environmental matters which includes social cultural surroundings, mentality etc. Therefore the life event stress could be one of critical factors of menopausal disorder. The diagnosis and treatment considering the life event stress could be effective method to relieve patient's menopausal disorder.

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