• 한국연소학회:학술대회논문집
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• 2004.11a
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• pp.85-90
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• 2004

We have presented characteristics of a transitional behavior from a premixed flame to a triple flame in a lifted flame according to the change of equivalence ratio. The experimental apparatus consisted of a slot burner and a contraction nozzle for a lifted flame. As concentration difference of the both side of slot burner increases, the shape of flame changed from a premixed flame to a triple flame, and the liftoff height is decreased to the minimum value and then increase again. Around this minimum point, it is confirmed a transition regime from premixed flame to triple flame. Consequently, the experimental results of the liftoff height, flame curvature and luminescence intensity showed that the stabilized laminar lifted flame regime is categorized by regimes of premixed flame, triple flame and critical flame. In the visualization experiment of smoke wire, the flow divergence and redirection reappeared in premixed flame as well as triple flame. Thus we cannot express the flame front of lifted flame has a behavior of triple flame with only flow divergence and redirection. To differentiate triple flame and premixed flame, ${\Phi}$ value of partially premixed fraction is employed. The partially premixed fraction ${\Phi}$ was constant in premixed flame. In critical flame small gradient appears over the whole regime. In triple flame, typical diffusion flame shape is obtained as parabolic distribution type due to diffusion flame trailing.

• Korean Journal of Clinical Pharmacy
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• v.22 no.2
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• pp.113-122
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• 2012

ACC/AHA/SCAI Guideline recommends for administration dual antiplatelet therapy after drug-eluting stent (DES) to prevent restenosis and stent thrombosis in patients with percutaneous coronary intervention (PCI). Recently triple antiplatelet therapy including cilostazol is known to reduce restenosis and stent thrombosis significantly after DES implantation. However, there is lack of data providing the efficacy of triple antiplatelet therapy. The purpose of this study is to evaluate the clinical effects of the triple therapy after DES implantation compared with the dual therapy. This retrospective study collected data from medical charts of 251 patients who received DES implantation between Jul 2006 and Jun 2008. They received either dual antiplatelet therapy (N = 154 clopidogrel and aspirin; Dual group) or triple antiplatelet therapy (N = 97 cliostazol, clopidogrel and aspirin; Triple group). Major adverse cardiac event rates (MACE, included total death, myocardial infarction, target lesion revascularization) at 12 months, 24 months, stent thrombosis, rates of bleeding complications and adverse drug reactions were compared between these two groups. Compared with the dual group, the triple group had a similar incidence of the MACE rates at 24months (12.3% vs. 12.4%, p = 0.99). There is no difference in overall stent thrombosis between two groups (Dual group 2.6% vs. Triple group 4.1%, p = 0.5). Subgroup analysis showed that diabetic patients got more benefit in reducing MACE rates but, there is no statistical difference. Bleeding complications and adverse drug effects were not different significantly. As compared with dual antiplatelet therapy, triple antiplatelet therapy did not reduce the 12-months, 24-months MACE rates and stent thrombosis. Bleeding complications and adverse drug effects were not different.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.6
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• pp.2577-2581
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• 2014

Background: Triple negative breast cancer is associated with aggressive behavior and high risk of local and regional failure. Aggressive surgical intervention is considered suitable. This makes role of breast conserving therapy (BCT) debatable in these patients. The objective of this study was to compare outcome of BCT for triple negative versus non-triple negative breast cancer. Materials and Methods: Medical records of patients who underwent breast conserving therapy from 1999 to 2009 at Shaukat Khanum Cancer Hospital and had complete receptor status information were extracted. Patients were divided into triple negative breast cancer (TNBC) and non-TNBC. Patient characteristics, medical treatment modalities and adverse events were compared. Expected five year locoregional recurrence free, disease free and overall survival was calculated. The Cox proportional hazard model was used to identify independent predictors of outcome. Results: A total of 194 patients with TNBC and 443 with non-TNBC were compared. Significant difference was present for age at presentation (p<0.0001), family history (p=0.005), grade (p<0.0001) and use of hormonal therapy (p<0.0001). The number of locoregional failures, distant failures and mortalities were not significantly different. No significant difference was present in 5 year locoregional recurrence free (96% vs 92%, p=0.3), disease free (75% vs 74%, p=0.7) and overall survival (78% vs 83%, p=0.2). On multivariate analysis, tumor size, nodal involvement and hormonal treatment were independent predictors of negative events. Conclusions: Breast conserving therapy has comparable outcomes for triple negative and non-triple negative breast cancers.

• Journal of Electrical Engineering and Technology
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• v.7 no.4
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• pp.615-625
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• 2012

GPS attitude outputs or carrier phase observables can be effectively utilized to compensate the attitude error of the strapdown inertial navigation system. However, when the integer ambiguity is not correctly resolved and/or a cycle slip occurs, an erroneous GPS output can be obtained. If the erroneous GPS output is applied to the attitude determination GPS/INS (ADGPS/INS) integrated navigation system, the performance of the system can be degraded. This paper proposes an ADGPS/INS integration system using the triple difference carrier phase observables. The proposed integration system contains a cycle slip detection algorithm, in which the inertial information is combined. Computer simulations and flight test were performed to verify effectiveness of the proposed navigation system. Results show that the proposed system gives an accurate and reliable navigation solution even when the integer ambiguity is not correctly resolved and the cycle slip occurs.

• Journal of Institute of Control, Robotics and Systems
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• v.9 no.9
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• pp.736-744
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• 2003

The GPS attitude output or carrier phase observables can be effectively utilized to compensate the attitude error of the strapdown inertial navigation system. However, when the integer ambiguity is not correctly resolved and/or a cycle slip occurs, an erroneous GPS output can be obtained. If the erroneous GPS information is directly applied to the AGPS/INS integration system, the performance of the system can be rapidly degraded. This paper proposes an AGPS/INS integration system using the triple difference carrier phase observables. The proposed integration system contains a cycle slip detection algorithm, in which inertial information is combined. Computer simulations and van test were performed to verify the proposed integration system. The results show that the proposed system gives an accurate and reliable navigation solution even when the integer ambiguity is not correct and the cycle slip occurs.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.29 no.3 s.234
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• pp.368-375
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• 2005

We have presented characteristics of a transitional behavior from a premixed flame to a triple flame in a lifted flame according to the change of equivalence ratio. The experimental apparatus consisted of a slot burner and a contraction nozzle for a lifted flame. As concentration difference of the both side of slot burner increases, the shape of flame changed from a premixed flame to a triple flame, and the liftoff height decreased to the minimum value and then increased again. Around this minimum point, it is confirmed a transition regime from premixed flame to triple flame. Consequently, the experimental results of the liftoff height, flame curvature, and luminescence intensity showed that the stabilized laminar lifted flame regime is categorized by regimes of premixed flame, triple flame and critical flame.

• The Journal of Korean Academy of Prosthodontics
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• v.55 no.4
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• pp.372-380
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• 2017

This study was conducted to compare the marginal and internal fit of all ceramic crown using the replica technique and the triple-scan protocol. Materials and methods: Twenty zirconia ceramic crowns were fabricated using titanium abutment model. All crowns were divided into two groups of 10 each, depending on the replica technique and the triple-scan protocol. The internal and marginal fit of 10 zirconia ceramic crowns were measured at 17 points for each specimen using the replica technique. The other 10 ceramic crowns were measured using the triple-scan protocol. Statistical analysis was performed by t-test (${\alpha}=.05$). Results: The mean and standard deviation of marginal and internal fit were significantly different between the replica technique ($49.86{\pm}29.69{\mu}m$) and triple-scan protocol ($75.35{\pm}64.73{\mu}m$, P<.001). The mean and standard deviation of internal fit except marginal fit were $58.38{\pm}31.77{\mu}m$ and $64.00{\pm}46.43{\mu}m$, respectively (P>.343). Conclusion: There was a statistically significant difference in the marginal fit measured by the two methods. However, there was no statistically significant difference in the internal fit between the two methods.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.6013-6017
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• 2013

Background: To evaluate the clinicopathologic and demographic characteristics of triple-negative breast cancer (TNBC) patients and to determine differences from non-triple-negative cases. Materials and Methods: A detailed review of the medical records of 882 breast cancer (BC) patients was conducted to obtain information regarding age, menopausal status, height and weight at the time of diagnosis, presence of diabetes or hypertension, and pathologic characteristics of the tumor (tumor size, lymph node status, histologic grade, ER status, PR status, HER2 status, p53 mutation). Body mass index (BMI) was calculated and a value of ${\geq}30$ was considered as indicative of obesity. Results: 14.9% (n=132) of the patients had TNBC. There was no difference among the patients in terms of median age, comorbid conditions and menopausal status. The proportion of medullary, tubular and mucinous carcinomas was significantly higher (15.9%) in the triple-negative (TN) group, while invasive lobular histology was more frequent (8.2%) among non-triple negative (NTN) cases (p<0.001). Grade 3 (G3) tumors were more frequent in the triple-negative group (p<0.001). The rate of p53 mutation was 44.3% in TN tumors versus 28.2% in the NTN group (p<0.001). The two groups were similar in terms of LN metastasis. In the NTN group, the rate of patients with BMI ${\geq}30$ was 53% among postmenopausal patients, while it was 36% among premenopausal women, and the difference was statistically significant (p<0.001). No significant difference was observed in terms of BMI between postmenopausal and premenopausal patients in the TN group (p=0.08). Conclusions: TNBC rates and clinicopathologic characteristics of the Turkish patient population were consistent with the data from Europe and America. However, no relationship between obesity and TNBC was observed in our study. The association between TNBC and obesity needs to be evaluated in a larger patient population.

• Journal of Power System Engineering
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• v.10 no.3
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• pp.23-31
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• 2006

Mean velocities and turbulent characteristics in the three-dimensional flow fields of a gun-type gas burner were measured by using triple hot-wire probe (T-probe) in order to compare them with the results already presented by X-type hot-wire probe (X-probe). Vectors obtained by the measurement of two kinds of probes in the horizontal plane and in the cross section respectively show more or less difference in magnitude each other, but comparatively similar shape in overall distribution. Axial mean velocity component along the centerline shows that the value by T-probe is about ten times smaller than that by X-probe above the range of X/R=3. Also, the axial component of turbulent intensity along the centerline appears the biggest difference between the two probes. Moreover, axial mean velocity component, axial turbulent intensity component and rotational along the Y-directional distance show a big difference between slits and swirl vanes. On the whole, the values by T-probe appear smaller than those by X-probe.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.2
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• pp.451-457
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• 2012

One decade early onset of the breast cancer in Iranian females was reported but the basis of the observed difference has remained unclear and difference in gene silencing by epigenetic processes is suggested. Hence, this study was sought to map the methylation status of estrogen receptor (ER) gene CpG islands and its impact on clinicopathological factors of triple negative and non-triple negative ductal cell carcinoma of the breast in Iranian females. Surgically resected formalin-fixed paraffin-embedded breast tissues from sixty Iranian women with confirmed invasive ductal carcinoma were assessed by methylation-specific PCR using primer sets encompassing some of the 29 CpGs across the ER gene CpG island. The estrogen and progesterone receptors, Her-$2^+$ overexpression, and nuclear accumulation of P53 were examined using immunohistochemistry (IHC). Methylated ER3, ER4, and ER5 were found in 41.7, 11.3, and 43.3% of the samples, respectively. Significantly higher methylation of ER4 was found in the tumors with nuclear accumulation of P53, and significantly higher methylation of ER5 was found in patients with lymph node involvement and tumor with bigger size or higher grades. Furthermore, significantly higher rate of ER5 methylation was found in patients with Her-$2^+$ tumors and in postmenopausal patients with $ER^-$, $PgR^-$, or $ER^-/PgR^-$ tumors. However, no significant difference in ERs methylation status was found between triple negative and non-triple negative tumors in pre- and postmenopausal patients. Findings revealed that aberrant hypermethylation of the ER-alpha gene frequently occurs in Iranian women with invasive ductal cell carcinoma of the breast. However, methylation of different CpG islands produced a diverse impact on the prognosis of breast cancer, and ER5 was found to be the most frequently methylated region in the Iranian women, and could serve as a marker of poor prognosis.