• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.392.3-393
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• 2002

The increase of triglyceride in blood can be a signal of an increasing danger of arterial diseases when insulin resistance. diabetes. HDL -cholesterol decrease is accompanied. It is adjusted to triglyceride level in blood by a balance. which seems to be absorbed from VLDL metabolism in liver and by lipoprotein lipase activity. The hyper-triglyceride disease treatment proposal role should match with suppression does into liver or elimination of a triglyceride. (omitted)

• Asian-Australasian Journal of Animal Sciences
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• 제20권4호
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• pp.563-568
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• 2007

This study was planned to investigate the role of Berberis lycium in reducing serum cholesterol in broilers. Six experimental rations designated as A, B, C, D, E and F having 0, 0.5, 1.0, 1.5, 2.0 and 2.5% Berberis lycium were fed to 240 broiler chicks, randomly distributed into 24 replicates, so as to have 4 replicates per group and 10 chicks per replicate. The experiment lasted for 35 days. Average serum total cholesterol, triglyceride, high density lipoprotein (HDL) and low density lipoprotein (LDL) were used as criteria of response. Average total serum cholesterol per chick was 129.33, 120.50, 116.50, 113.00, 101.67 and 114.00 mg/dl for group A, B, C, D, E and F respectively. Total serum cholesterol showed decreasing trend with the increasing level of Berberis lycium unto 2% (p<0.05). Mean serum triglyceride level per chick was 60.00, 58.17, 58.00, 55.33, 50.17 and 48.50 mg/dl for group A, B, C, D, E and F respectively. Mean serum triglyceride showed decreasing trend with the increasing level of Berberis lycium (p<0.05). Serum triglyceride was significantly lower in group F than other groups. Mean HDL per chick for the six experimental groups A, B, C, D, E and F was 52.08, 53.42, 60.42, 62.25, 62.92 and 54.50 mg/dl respectively. HDL showed increasing trend with the increase in the level of Berberis lycium unto 2%. The average serum LDL per chick was 65.25, 55.45, 44.48, 39.68, 28.72 and 49.80 mg/dl for group A, B, C, D, E and F respectively. LDL also showed decreasing trend with the increase in the level of Berberis lycium unto 2% (p<0.05). It was concluded that Berberis lycium added to feed at the rate of 2.0% can be used in broiler feed for reducing serum total cholesterol, triglyceride and LDL and increasing HDL.

• 한국식품과학회지
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• 제33권4호
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• pp.492-496
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• 2001

혈청 중성지질 저하작용을 가지고 있는 것으로 알려진 OA식 및 DEHP식을 각각 투여한 흰쥐의 간장 및 소장에서 MTP 활성과 mRNA 수준을 검토하였다. 간장 중성지질 농도는 대조군에 비교해서 OA군에서 유의하게 증가하였으나, DEHP군에서는 유의한 차이가 없었다. 혈청 중성지질 농도는 대조군에 비해서 OA군 및 DEHP군에서 유의하게 감소하였는데, 이러한 저하는 OA군에서 더욱 현저하였다. 간세포에서의 MTP 활성과 mRNA 수준은 대조군에 비해서 OA군에서 유의하게 저하하였으나, 소장에서의 MTP 활성은 증가하였다. 그러나, 간장 및 소장의 MTP 활성과 mRNA 수준은 대조군과 DEHP군 사이에서는 유의적인 변화가 없었다. 간장에 있어서 중성지질 합성의 중요 조절효소인 microsomal PAP 활성은 대조군에 비해 OA군에서 유의하게 증가하였으나, DEHP군에서는 cytosolic PAP 활성이 감소하였다. 이상의 결과로부터, OA에 의한 혈청 중성지질 저하 작용에는 간장 MTP 활성과 mRNA 유전자 발현이 깊이 관여하였으나, DEHP에 의한 혈청 중성지질 저하 작용에는 MTP 대사와는 무관한 것으로 사료되었다.

• 한국간호교육학회지
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• 제10권2호
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• pp.289-296
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• 2004

The purpose of this study was examine the relationship between smoking, general characteristics, and serum lipids in the normal adult. The subjects consist of 6,800 persons (male ; 4,309(63.4%), female ; 2,491(36.6%)) in A hospital in Kyungki-Do. The collected data were analyzed using T-test, and Multiple Regression by SPSS/WIN program. The result were following ; 1. Cigarette smoking was associated with decreased serum HDL cholesterol level (p<.001). 2. Serum LDL cholesterol level was not statistically correlated with smoking tend to level by 5.77mg/dl respectively. 3. Cigarette smoking was associated with elevated serum Triglyceride level (p<.001). 4. By using regression, HDL cholesterol level was negatively correlated with obesity and alcohol.. HDL cholesterol level was positively correlated with exercise. LDL cholesterol level was positively correlated with diet and obesity.　Triglyceride level was positively correlated with obesity and　alcohol. In conclusion, Smoking was the most correlated with Triglyceride among the serum lipid and Serum lipid was the most correlated with obesity. Thus, it is necessary to quit smoke and weight control for prevention from disease such as coronary heart disease and lung cancer.

• 한국식품영양과학회지
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• 제24권4호
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• pp.523-529
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• 1995

Administration of an MeOH extract of Pharagmites communis on hyperlipidemic rats produced a significant decrease in blood triglyceride. The fatty acid mixtures, $\beta$ -sitosterol and its glucoside, p-coumaric acid, vanilic acid, ferulic acid, p-hydroxybenzaldehyde and sucrose were isolated. Sterol and p-coumaric acid were shown to be effective in reducing the elevated level of triglyceride. The wet weight and the level of triglyceride in epididymal adipose tissue increase following administration of the methanol extract in rats fed the purified diets at the 1% level for 4 weeks. This results suggest that the methanol extract may accelerate the accumulation of lipid in adipose tissue.

• 대한한방내과학회지
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• 제40권3호
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• pp.517-524
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• 2019

Objectives: This study reported the progress of herbal medicine administration for hypertriglyceridemia. Methods: Patients diagnosed with hypertriglyceridemia were treated with Taiyintiaowei decoction three times a day. After the triglyceride level dropped, we prescribed Wujisan decoction three times a day to maintain the normal range of triglycerides. Results: The patients' blood triglyceride level decreased from 432 mg/dL to 113 mg/dL. The triglyceride level remained steady in the normal range. Adverse events were not observed. Conclusions: Herbal medicines may be effective in controlling hypertriglyceridemia. Further studies on related topics are needed.

• 혜화의학회지
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• 제12권2호
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• pp.1-9
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• 2004

1. Purpose Stroke is the most frequent cause of mortality and morbidity rate in Korea with coronary heart disease and cancer. The ischemic type of stroke is increasing tendency. The purpose of this studies is to examine the hematologic difference between cb infarction patients and Korean normal adults. 2. Method The study group consisted of neurologically confirmd 50 cb-infarction patients as the case group and 278 patients as control group that they had no significant result by CT through early examination of stroke in Cheonan oriental hospital of Daejeon university. We tested and compared RBC, hemoglobin, hematocrit, WBC, PT, PTT, total protein, albumin, total bilirubin, direct bilirubin, GOT GPT, $\gamma$-GTP, total cholesterol, triglyceride, HDL-C, glucose, BUN, creatinine, Na, K in the both group. 3. Result In the sample group(cb infarction group), there were many patients with low RBC count but no significant and with low hemoglobin, hematocrit(p<0.05). Thereas, increased WBC count and delayed PTT were showed respectively 20%, 36% in patient group, 7.9%, 4.7% in normal group(p<0.05). Comparing the LFT between cb infarction patients and normal adults, we founded significant cases with low HDL-C level, high glucose level, low potassium level in patient group(p<0.05). But the percentage of high total cholesterol level and triglyceride level were 18%, 29%(norma1 group), 20%, 28%(cb infarction group) respectively, there were no significant difference. 4. Conclusion In this study, we demonstrated that low HDL-C level and high glucose level is one of important risk factor of cb infarction. Also prospective studies are needed to evaluate many risk factor(hemoglobin, hematocrit, WBC, cholesterol, triglyceride, K, etc) of cb infarction.

• 한국식품영양학회지
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• 제26권2호
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• pp.242-248
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• 2013

Our objectives in this experiment were to study the effects of oils that are high in contents of unsaturated fatty acids (olive, flaxseed, and perilla oils) and pyroligneous liquor on plasma lipid concentrations in mice. Male ICR-mouse (n=10 per group) were fed powdered form diets containing oil and pyroligneous liquor for 60 days. The cholesterol level of the PP group ($96.71{\pm}25.75$ $mg/d{\ell}$) was lower than that of the COW group ($133.56{\pm}21.53$ $mg/d{\ell}$). Levels of triglyceride of COP, CFP, and CPP groups were $121.10{\pm}50.79$ $mg/d{\ell}$, $77.80{\pm}38.58$ $mg/d{\ell}$, and $92.40{\pm}33.04$ $mg/d{\ell}$, respectively (p<0.05). The dietary addition of olive oil increased the plasma lsevels of cholesterol and LDL-cholesterol. On the other hand, the dietary addition of flaxseed oil and pyroligneous liquor increased the plasma level of HDL-cholesterol and decreased the plasma levels of LDL-cholesterol and triglyceride compared with those of the control group. Further, the dietary addition of perilla oil decreased plasma triglyceride but increased HDL-cholesterol. The decrease in the cholesterol level was much higher in the CFP group. In conclusion, the dietary addition of long-term pyroligneous liquor effectively decreased the plasma levels of cholesterol and triglyceride and increased the plasma level of HDL-cholesterol. The additional dietary administration of flaxseed and perilla oils increased the effect of pyroligneous liquor.

• Journal of Preventive Medicine and Public Health
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• 제25권1호
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• pp.44-52
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• 1992

This study was conducted to evaluate the relations between alcohol intake and blood lipid level in a group of 1,138 Korean adult men, ages 20 to 69 years. Total number of each of a variety of drinks in the previous two weeks was obtained by questionnaire and converted into grams of alcohol consumed in a week. The levels of blood lipid such as Cholesterol, HDL-Cholesterol, Triglyceride and LDL-Cholesterol were examined by enzyme method. We also observed the effects of various variables such as age, body mass index, smoking, exercise and blood pressure on blood lipid level. The results obtained were as follows : 1. Average weekly alcohol intake was $129.0{\pm}167.4gm$ and that of 30-39 age group was the highest as $149.3{\pm}170.4gm$. 2. Levels of Cholesterol Triglyceride and LDL-Cholesterol tended to increase with increasing age, but level of HDL-Cholesterol showed no significant relationship with age. 3. The positive linear regressions of alcohol intake on HDL-Cholesterol and Triglyceride were noted statistically significant. 4. Multiple regression analysis demonstrated that the effect of alcohol on HDL-Cholesterol and Triglyceride was statistically significant and the contribution rates were 5.0% and 0.8%, respectively. And, in the case of HDL-Cholesterol, the alcohol intake was the most significant independent variable.

• 한국지역사회생활과학회지
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• 제24권1호
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• pp.141-149
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• 2013

The objective of this study is to find the effect of improving hyperlipidemia through Platycodi radix saponin. A hypercholoesterol diet and Platycodi radix saponin methanol extract were supplemented to the 6 week old male Spargue Dawley rats for four weeks. Results showed that the serum total cholesterol, triglyceride and LDL-cholesterol level decreased in the group supplemented with Platycodi radix saponin methanol extract(p<0.05), however, the serum total lipid and HDL-cholesterol did not show any difference from the control group according to the supplement of Platycodi radix saponin methanol extract. In the group supplemented with Platycodi radix saponin methanol extract, the total cholesterol decreased by 20%, triglyceride by 36% and LDL-cholesterol by 25% respectively, and there was no difference according to the level of Platycodi radix saponin methanol extract. AI(atherogenic index) and CRF(cardiac risk factor) were low in the group supplemented with Platycodi radix saponin methanol extract. Total lipid, total cholesterol and triglyceride in liver and feces were significantly low in the group supplemented with the Platycodi radix saponin methanol extract compared with the control group(p<0.05). According to this result, it is expected that the Platycodi radix saponin methanol extract supplemented in the hypercholesterol diet can lower atherosclerosis, the cause of cardiovascular disease, by reducing not only serum cholesterol and triglyceride but also liver cholesterol and triglyceride.