• Journal of Nutrition and Health
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• v.36 no.6
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• pp.589-602
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• 2003

This study was designed to investigate the effects of weight reduction and changes in serum lipid composition using a commercial uncooked powdered food (UPF) diet on 27 obese hyperlipidemic women over a period of 12 weeks. We replaced the standard breakfast and dinner of each of the subjects with UPF. Their dietary intake status was evaluated by 24-hour recall method. Their body compositions were measured using a body fat analyzer. Also, we conducted hematological, clinical and lipid profile analyses of their blood. Their intake of energy, lipid and protein significantly decreased as the subjects started to take UPF, but their intake of vitamins and minerals, other than iron, increased. Due to the energy intake decrease, the subjects' weight, body fat and waist circumference significantly decreased. Among the lost weight the percentage of the body fat was high. We judged that this process of losing weight was successful in obese hyperlipidemic women. Serum HDL-cholesterol gradually increased and serum total-cholesterol, LDL-cholesterol, triglyceride levels showed gradual decreases. When obese hyperlipidemic women replaced two of three meals with UPF for 3 months, we were able to see useful changes like decreased body fat and serum lipid. Complete judgment on the usefulness of UPF may be difficult but if people take a standard meal once a day and replenish their iron by taking UPF twice a day, we assume that replacing UPF with balanced regular meal not be a problem in nutritional status. Our results show that UPF is effective in the diet therapy of obese hyperlipidemic women.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.5
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• pp.811-815
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• 1994

In this study the quantity and the ratio of saturated and unsaturated fatty acids were investigated with using gas chromatography after non-polar lipid of the flint corn in the growing period was extracted with the solution of chloroform : methanol (2 : 1) and then separated by the SACC method. Neutral lipid was separated into monoglyceride(MG), 1, 3-diglyceride (1, 3-DG) , free fatty acid (FFA) , triglyceride (TG), cholesteryl ester (CE). Fatty acid of each spot was mainly composed of linoleic , oleic and palmitic acids. Lonolieic acid decreased in MG(54.5-51.4%), CE(31.3-28.9%) but increased ini TG(57.2-63.8%) during growth process. Olec acid increased in MG(25.7-29.3%), 1, 3-DG(24.7-28.9%), CE(16.7-19.9%) but decreased in TG28.6-23.1%). Palmitic acid decreased in MG(12.8-11.5%), FFA(25.7-24.1%), TG(10.4-9.3%) but increased in CE(26.4-31.5%) during a growth process. The ratio of unsaturated to saturated fatty acid in TG(7.01-7.84%) was higher in five spots of neutral lipid and in 1, 3-DG(4.61-4.16%) decreased growth process but increased in MG(5.06-5.60%), TG(7.01-7.84%).

• Journal of Environmental Science International
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• v.22 no.1
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• pp.37-45
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• 2013

The monthly variations of blood characteristics and RNA/DNA of black sea bream, Acanthopagrus schlegeli, habituated in Geojae costal area were analysed to determine health condition of natural stocks in terms of gonad maturation and spawning season from March 2010 to February 2011. Spawning season determinated by gonadosomatic index is from June to August. RNA/DNA ratio of black sea bream muscle was strongly correlated with spawning season. During the gonad maturation RNA/DNA ratio in dorsal muscle tissue was decreased contrast to rapid increase during spawning season. Blood composition factors increased in terms of gonad maturation are aspartate aminotransferase, cholesterol, triglyceride, total protein, glucose, globulin, alkaline phosphatase and inorganic phosphate. Other blood factors increased during spawning season are alanine aminotransferase, blood urea nitrogen, uric acid and lactate dehydrogenase.

• Journal of Veterinary Clinics
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• v.21 no.3
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• pp.259-263
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• 2004

This study was conducted to investigate the growth rate and hematological changes of the rats when supplemented with the powdered tubers of chufa(Cyperus esculentus) for four weeks. Nutritional composition of the powdered tuber of chufa is crude lipid(22.3%), crude protein(7.0%), crude fiber(8.8%), ash(5.1%), nitrogen free extract(48.9%) and water(7.9%), respectively. Sixteen Sprague-Dawley male $rats(173.1\pm3.8$ g) were randomly divided into two groups, control group and chufa group. Rats in control group were fed with American Institute of Nutrition(AIN)-76 diet and rats in chufa group were fed with modified AIN-76 diet contained the powdered tubers of chufa at the proportion of 26% of total diet in order to substitute the oil content of AIN-76 diet. Final body weight, gain of body weight and feed intake of rats in chufa group were larger than those of rats in control group significantly. But feeding efficiency of rats in chufa group was less than that of rats in control group significantly. All hematological values such as hemoglobin concentration and hematocrit and serological values such as glucose, total protein, albumin, AST, ALT, cholesterol, high density lipoprotein-cholesterol and triglyceride were not significantly different between control and chufa group, respectively. Thus powdered tuber of chufa showed good tastefulness and did not provoke any adverse effect to the health indicators of rats. Therefore tuber of chufa would be used as new adequate feed resource for animals and possibly as suitable food resource for humans.

• Journal of Environmental Health Sciences
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• v.10 no.1
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• pp.99-106
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• 1984

The diets used to this experiment were composed only of stock diet for group A, a mixture of stock diet and 2% cholesterol for group B, and 5%, 10% perilia powder for group C, D and 5%, 10% pine nut for group E, F in addition to group B diet respectively. All groups fed with these experimental diets for 3 weeks were fasted for 15 hours at the end of the experiment, and then they were decapitated to take serum. The serum was used to measure the level of glucose, total cholesterol, triglyceride, HDL-cholesterol and lipoprotein composition. The results were summarized as follows. 1. Perilla and pine nut diets have no influence on body weight and food intake in cholesterolfed male rats 2. The blood glucose level was not changed significantly at groups C-F. 3. Total cholesterol level was significantly decreased by 21.6% ~ 29.7% at group C-F than at group B. 4. HDL-cholesterol level was increased by 51.3% ~ 86.1% at group C-F than at Group B. 5. The $\alpha/\beta$ ratio which is 0.51 at the group A was risen to 0.99 at the group B. However, this ratio was decreased to 0.5 0 - 0.51 at group C, D and to 0.68 - 0.69 at group E.F.

• Journal of the Korean Society of Food Science and Nutrition
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• v.26 no.3
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• pp.507-513
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• 1997

This study was carried out to examine whether kimchi has hypolipidemic effect and to know how it exert lipid-lowering effect in rats. Male Sprague-Dawley rats were fed with kimchi-fee diet, or 3%, or 5%, or 10% kimchi diets for 6 weeks. Plasma cholesterol level was lowered in rats fed all concentrations of kimchi diets, and plasma triglyceride(TG) level was lowered in 10% kimchi diet group compared with that of control significantly(p<0.05). Th intake of kimchi lowered VLDL-cholesterol and VLDL-TG levels, whereas increased HDL-cholesterol level significantly(p<0.05). LDL-cholesterol level was lowered only in 5% kimchi diet group and LDL-TG level was lowered in all kimchi diet groups compared with those of control significantly (p<0.05). the intake of 5% and 10% kimchi diets also lowered the levels of hepatic cholesterol, TG, total lipid, and apolipoprotein B, whereas increased the levels of fecal total fat, cholesterol, TG, and apolipoprotein A-1 significantly(p<0.05). Triiodothyronine(T$_3$) level was elevated in rats fed kimchi diet, whereas thyroxine(T$_4$) level was not affected by kimchi treatment. These observations support that the intake of kimchin in rats loweres plasma and hepatic lipid levels by increasing the excretion of TG and cholesterol through feces, by the elevation of T$_3$ level, and by the altered lipoprotein metabolism.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.4
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• pp.517-522
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• 1995

The present study has been undertaken to investigate the effect of plantaginis semen extract on lipid composition and activities of several enzymes in lard administrated rats. Forth male rats of Sprague-Dawley strain with average weight of 130$\pm$10g were divided into four groups[basal diet(BD)], basal＋plantaginis semen(BP), basal＋lard(BL) and basal＋plantaginis semen＋lard(BLP). Lard administrated groups showed increase in weight gain and that of BLP group significantly increased. Feed intake showed no significant differences with lard administration. The weights of liver, kidney and heart of the rat were not affected by plantagins semen and lard administration. Serum and liver triglyceride and cholesterol contents significantly increased compared to BD group but significantly decreased by the addition of plantaginis semen extract(BLP group). Serum and liver phsophlipids decreased in lard administrated group but effectively restored by administration of plantaginis semen extract. HDL-cholesterol content significantly decreased in lard-fed group and somewhat increased in plantaginis semen extract group. Serum aminotransferase, lactate dehydrogenase activities significantly increased in lard fed group but addition of plntginis semen extract significantly decreased the enzyme activities compared with that of lard administrated group.

• Journal of the Korean Society of Food Science and Nutrition
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• v.19 no.1
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• pp.1-12
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• 1990

To investigate effects of ethanol and dietary fat on growth and bichemical indices of liver tissue and blood in rats 40 male rats of Sprague-Dawley wtrain weighing about 160g were divided into 5 groups (low-fat diet group ethanol-administered low-fat diet group high-fat diet group ethanol-administered high-fat diet group and commercial diet group) and fed expe-rimental diets for 8 weeks. Ethanol-administered groups consumed ethanol corresponding to 22 cal% which was considered as moderate drinking. Neither the ethanol intake nor the dietary fat level affected calorie intake. Nonetheless the low-fat diet group with ethanol had the lowest growth rate and 2-fold increase in the concentration of plasma triglyceride. There was no effect of ethanol and dietary fat level on contents of protein lipid and lipid composition of liver tissue. The level of lipid peroxide of liver tissue tended to be increased by ethanol intake but the increase was statistically insignificatnt. The low-fat ethanol group had lowered hepatic mitochondrial respiration rate and deformed structure of mitochondria of hepatocytes.

• Journal of the Korean Society of Food Science and Nutrition
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• v.19 no.4
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• pp.279-284
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• 1990

This experiment was conducted to study the effect of dietary vitamin E on the lipid composi-tion of rats treated with carbon tetrachloride. Rats were divided into five groups I. e. C(soybean oil with vitamin E(40mg/kg diet)) EF(CCl4 with vitamin E deficient diet) 40E(CCl4 with vitamin E(40mg/kg diet) 400E(CCl4 with vitamin E(400mg/kg diet) 800E(CCl4 with vitamin E(800mg/kg diet) Body weight gain and food efficient ratio were not observed significant differences. The liver weight was significantly increased in the CCl4 treated groups but the liver weight of 800E group was significantly lower than that of EF group. In EF and 40E groups kidney weights were significantly higher compared to that of C group. The content of total lipid in liver of 40E and 400E groups were significantly higher than that of control group but in 400E and 800E groups the contents were significantly lower compared with that of EF group. The content of triglyceride in liver was significantly higher in the CCl4 treated group and the content of cholesterol was significantly higher in the EF and 40E groups but those of 800E group were significantly lower compared with those of EF group. In CCl4 administration groups were significantly higher than those of control group and 400E and 800E groups were significantly lower than those of EF group.

• Asian-Australasian Journal of Animal Sciences
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• v.5 no.1
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• pp.123-128
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• 1992

In Experiment 1, when fasted chicks were fed diets containing various sources of protein for 3 days, the activities of lipogenic enzymes (acetyl-CoA carboxylase, fatty acid synthetase, citrate cleavage enzyme and malic enzyme) in the liver of growing chicks were significantly lower in the soybean protein or gluten diet than in the casein or fish protein diet. Triglycride contents of the liver and plasma of chicks fed the casein or fish protein diet were significantly lower than that of those fed soybean protein or gluten diet. In Experiment 2, the effects of dietary amino acid mixture simulating casein or protein on the activities of hepatic lipogenic enzymes were examined. The activities of acetyl-CoA carboxylase and fatty acid synthetase in the liver of chicks fed the casein diet were significantly higher than that of those fed the soybean protein diet or two diets of amino acid mixtures. Furthermore, there were no significant differences between the two diets of amino acid mixture based on casein or soybean protein. However, the activities of malic enzyme and citrate cleavage enzyme tended to be lower in the soybean-type amino acid diet than in the casein-type amino acid diet. Thus, some effects can be ascribed to the protein itself and some to the amino acid composition of the protein sources.