• 한국작물학회지
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• 제48권2호
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• pp.127-133
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• 2003

The purpose of this study is to investigate the positive or negative effects of 5-aminolevulinic acid(ALA) on the growth of several crops and weeds, by applying a seed soaking treatment, foliar treatment, and application timing, while comparing biological activity between ALA produced by chemical synthesis (Synthetic-ALA) and extracellularly-accumulated ALA by overexpressing the hemeA gene isolated from Bradyrhizobium japonicum(Bio-ALA). Seed soaking treatment of ALA in barley (five cultivars) and wheat (five cultivars) had not shown positive effects at lower concentrations, 0.05 to 0.5 mM as well as negative effects at higher concentrations, 1 to 30 mM. In rice, there also was no positive effect by seed soaking treatment of ALA at lower concentrations, although the rice became damaged by an application of 5 and 10 mM ALA. Growth in barley cultivars, Ganghossalbori, Naehanssalbori, Songhakbori, Saessalbori, and Daehossalbori were increased up to 14%, 19-51 %, 17-64%, 18-23%, and 22-38% by ALA foliar application at lower concentrations, 0.05 to 0.5 mM, respectively. On the other hand, the growth in barley cultivars was inhibited by ALA foliar application at higher concentrations. Barley responded more positively to ALA foliar application than wheat and rice. The growth stimulation caused by ALA seed soaking treatment was less than by ALA foliar treatment. ALA treatment at the 1.5-leaf stage increased growth of barley by 19-58%, while pretreatment to seeds, post-emergence treatment at 3 days after seeding, 3-leaf stages, and 5-leaf stages had not shown positive effects. Thus, the positive effects of ALA on barley were dependent greatly upon the timing of application and its concentration. Monocots weeds were more sensitive to ALA foliar treatment than dicotyledonous weeds. A monocot weed, Setaria viridis L. was the most susceptible plant to ALA while a dicotyledonous weed, Plantago asiatica L. was the most tolerant. No significant difference in biological activity between bio-ALA and synthetic ALA on barley, wheat, rice, and weed, Ixeris dentate tested was observed. Thus, ALA produced by microorganisms would be a potent substance to be used effectively in agricultural production.

• 대한치과교정학회지
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• 제32권5호
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• pp.301-312
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• 2002

상악골 전방견인 장치를 이용한 골격성 III급 부정교합 환자의 악정형적 치료에서 치료시기는 치료효과에 지대한 영향을 미칠 수 있으며 이상적인 치료시기는 연구자에 따라 다소의 차이는 있으나 다른 형태의 부정교합보다는 다소 이른 사춘기 이전의 어린 나이라는 것이 선학들의 공통된 의견이었다 하지만 통계적 자료들을 바탕으로 한 최근의 논문들은 과거 선학들의 의견을 뒷받침 해주는 논문과 그렇지 않은 논문들로 나뉘고 있어 이상적 치료시기에 대한 정립된 의견이 없는 실정이다. 이에 본 연구에서는 119명의 환자들의 수완부골 방사선 사진을 평가하여 골성숙도에 따라 사춘기전군과 사춘기군으로 분류하고 치료전후 측모두부방사선 사진을 분석하여 상악골 전방견인에 대한 치료효과를 비교하였다. 평균 치료기간은 사춘기전군은 6.5개월, 사춘기군은 6.1개월이었으며 치료전후의 측모두부방사선 사진을 분석한 결과 다음과 같은 결론을 얻었다. 1. 상악골의 전방이동양은 사춘기전군과 사춘기군간에 차이가 없었다. 2. 상악골의 하방이동양은 사춘기전군과 사춘기군간에 차이가 없었다. 3. 하악골의 하방이동양과 후하방회전양은 사춘기전군과 사춘기군간에 차이가 없었다. 4. 치성이동양은 사춘기전군과 사춘기군간에 차이가 없었다. 이상의 결과로 사춘기전 뿐 아니라 사춘기에서도 상악골 전방견인에 의해 상악골 성장촉진과 함께 성공적인 악정형 치료가 가능함을 알 수 있었다.

• Journal of Trauma and Injury
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• 제22권1호
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• pp.77-86
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• 2009

Purpose: The appropriate management of traumatic truncal arterial injury is often difficult to determine, particularly if the injury is associated with severe additional truncal lesions. The timing of repair is controversial when patients arrive alive at the hospital. Also, there is an argument about surgery versus stent-graft repair. This study's objective was to evaluate the appropriate method and the timing for treatment in cases of truncal abdominal injury associated with other abdominal lesions. Methods: The medical records at Ajou University Medical Center were reviewed for an 8-year period from January 1, 2001, to December 31, 2008. Twelve consecutive patients, who were diagnosed as having had a traumatic truncal arterial injury, were enrolled in our study. Patients who were dead before arriving at the hospital or were not associated with abdominal organ injury, were excluded. All patients involved were managed by using the ATLS (Advanced Trauma Life Support) guideline. Data on injury site, the timing and treatment method of repair, the overall complications, and the survival rate were collected and analyzed. Results: Every case showed a severe injury of more than 15 point on the ISS (injury severity score) scale. The male-to-female ratio was 9:3, and patients were 41 years old on the average. Sites of associated organ injury were the lung, spleen, bowel, liver, pelvic bone, kidney, heart, vertebra, pancreas, and diaphragm ordered from high frequency to lower frequency. There were 11 cases of surgery, and one case of conservative treatment. Two of the patients died after surgery for truncal organ injury: one from excessive bleeding after surgery and the other from multiple organ failure. Arterial injuries were diagnosed by using computed tomography in every case and 9 patients were treated by using an angiographic stent-graft repair. There were 3 patients whose vessels were normal on admission. Several weeks later, they were diagnosed as having a truncal arterial injury. Conclusion: In stable rupture of the truncal artery, initial conservative management is safe and allows management of the major associated lesions. Stent grafting of the truncal artery is a valuable therapeutic alternative to surgical repair, especially in patients considered to be a high risk for a conventional thoracotomy.

• Journal of Yeungnam Medical Science
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• 제40권1호
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• pp.12-22
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• 2023

Graves disease (GD) is the most common cause of hyperthyroidism, accounting for more than 90% of cases in Korea. Patients with GD are treated with any of the following: antithyroid drugs (ATDs), radioactive iodine (RAI) therapy, or thyroidectomy. Most patients begin treatment with ATDs, and clinical guidelines suggest that the appropriate treatment period is 12 to 18 months. While RAI treatment and surgery manage thyrotoxicosis by destroying or removing thyroid tissue, ATDs control thyrotoxicosis by inhibiting thyroid hormone synthesis and preserving the thyroid gland. Although ATDs efficiently control thyrotoxicosis symptoms, they do not correct the main etiology of GD; therefore, frequent relapses can follow. Recently, a large amount of data has been collected on long-term ATDs for GD, and low-dose methimazole (MMZ) is expected to be a good option for remission. For the long-term management of recurrent GD, it is important to induce remission by evaluating the patient's drug response, stopping ATDs at an appropriate time, and actively switching to surgery or RAI therapy, if indicated. Continuing drug treatment for an extended time is now encouraged in patients with a high possibility of remission with low-dose MMZ. It is also important to pay attention to the quality of life of the patients. This review aimed to summarize the appropriate treatment methods and timing of treatment transition in patients who relapsed several times while receiving treatment for GD.

• 한국기계가공학회지
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• 제9권6호
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• pp.7-15
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• 2010

Recently, with the high performance and efficiency of machine, there have been required the multi-functions in various machine parts, such as the heat resistance, the abrasion resistance and the stress resistance as well as the strength. Fatigue crack growth tests were carried out to investigate the fatigue characteristics of high carbon steel (SM53C) experienced by high-frequency induction treatment. The Cam nose part of the Automobile's Cam shaft is strongly bumped with rocker arm or valve-lift. Therefore abnormal wear such as unfair wear and early wear occur in the surface. This abnormal wear causes a defect that bad timing open and close actions of the engine valve happen in the combustion chamber so the fuel gas will be combustion imperfect. Therefore, the cam shaft demands high hardness and wear resistance. In this study, high frequency heat treatment has been accomplished while wear test for material SM53C.

• 대한치과교정학회지
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• 제29권1호
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• pp.129-136
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• 1999

유착, 부적절한 교정치료, 과잉치, 낭종, 비정상적인 맹출경로등의 국소적인 원인으로 인하여 구치부의 매복이 발생할 수가 있다. 매복치는 적절한 치료를 하지 않으면, 교합기능의 상실, 영구치의 상실, 대합치의 정출, 인접치의 치근흡수등을 야기 할 수가 있다. 매복치를 성공적으로 맹출유도하기 위해서는 매복치의 치근형성여부가 중요한 요소가 되며, 매복치의 치근형태, 주위환경등을 유의한 적절한 교정력이 가해져야 한다.

• Journal of Trauma and Injury
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• 제35권1호
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• pp.46-50
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• 2022

Traumatic flank hernia (TFH) is rare and prone to recurrence, which makes appropriate treatment challenging. No current guidelines define the optimal timing and method of repair. Meanwhile, recent advances in laparoscopic techniques are reshaping the options for the treatment of TFH. A dual approach that utilizes both laparoscopic and open methods has not previously been reported. Herein, we present the successful treatment of TFH after blunt trauma. A 46-year-old male patient underwent elective herniorrhaphy on hospital day 3, in which laparoscopic implantation of a sublay mesh and extracorporeal implantation of an onlay mesh were performed. Such techniques may be appropriate and result in feasible outcomes in hemodynamically stable patients with large TFH who are strongly suspected of having bowel herniation or concomitant intraperitoneal injuries. Larger studies are needed to assess the long-term results.

• 대한음성언어의학회:학술대회논문집
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• 대한음성언어의학회 1997년도 제8회 학술대회 심포지움
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• pp.262-262
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• 1997

말더듬(stuttering)이란 언어-운동조절의 장애를 일으키는 운동장애(movement disorder)의 일종으로 혀, 입술, 후두를 이루는 근육과 호흡근육 등의 시간적인 부조화(inappropriate timing)로 특징지어지는 유창성장애(fluency disorder)의 하나로 인식되어 왔다. 여태까지 행동치료(behavioral treatment), 정신과적인 치료(psychiatric modalities)등이 치료의 방법으로 이용되어왔으며, 초기에는 비교적 좋은 반응을 보이나 지속적인 효과에 대해서는 회의적인 경우가 많았다. (중략)

• 생물정신의학
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• 제5권2호
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• pp.175-183
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• 1998

To consider current concepts of epilepsy further, the brief review begins with a discussion of what is epilepsy, discribes multifactorial nature of epileptic disorders, and ends with a presentation of current classifications. A combination of the standard antiepielptic drugs(AEDs) may be necessary to treat intractable seizures, but no studies have been done to indicate an optimal combination. The new AEDs provide alternative choices, but questions remain about the optimal timing and manner of administration. AEDs selection must individualized, no drug of choice can be named for all patients.

• 원예과학기술지
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• 제33권6호
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• pp.845-853
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• 2015

The objective of this study was to predict the timing of nitrogen (N) demand through analyzing chlorophyll fluorescence (ChlF), soil-plant analysis development (SPAD), and normalized difference vegetation index (NDVI), which are positively correlated with foliar N concentration in star cluster (Pentas lanceolata). The plants were grown in potting soil under optimal conditions for 30 d, followed by weekly irrigation with five concentrations (0, 4, 8, 16, and 24 mM) of N for an additional 30 d. These five N application levels corresponded to leaf N concentrations of 2.62, 3.48, 4.00, 4.23, and 4.69%, respectively. We measured 13 morphological and physiological parameters, as well as the responses of these parameters to various N-fertilizer treatments. The general increases in Dickson's quality index (DQI), above-ground dry weight (DW), total DW, flowering rate, ${\Delta}F/Fm$', and qP in response to treatment with 0 to 8 mM N were similar to those of SPAD, NDVI, and Fv/Fm. Consistent and strong correlations ($R^2$= 0.60 to 0.85) were observed between leaf N concentration (%) and SPAD, NDVI, ${\Delta}F/Fm$', and above-ground DW. Validation of leaf S PAD, NDVI, and ${\Delta}F/Fm$' revealed that these vegetation indices are accurate predictors of leaf N concentration that can be used for non-destructive estimation of the proper timing for N-solution irrigation of P. lanceolata. Moreover, irrigation with 8 mM N-fertilizer i s recommended w hen leaf N concentration, SPAD, NVDI, and ${\Delta}F/Fm$' ratios are reduced from their saturation values of 4.00, 50.68, 0.64, and 0.137%, respectively.