• Title/Summary/Keyword: treatment strategy

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Surgical Treatment of Gastroesophageal Junction Cancer

  • Hashimoto, Tadayoshi;Kurokawa, Yukinori;Mori, Masaki;Doki, Yuichiro
    • Journal of Gastric Cancer
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    • v.18 no.3
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    • pp.209-217
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    • 2018
  • Although the incidence of gastroesophageal junction (GEJ) adenocarcinoma has been increasing worldwide, no standardized surgical strategy for its treatment has been established. This study aimed to provide an update on the surgical treatment of GEJ adenocarcinoma by reviewing previous reports and propose recommended surgical approaches. The Siewert classification is widely used for determining which surgical procedure is used, because previous studies have shown that the pattern of lymph node (LN) metastasis depends on tumor location. In terms of surgical approaches for GEJ adenocarcinoma, a consensus was reached based on two randomized controlled trials. Siewert types I and III are treated as esophageal cancer and gastric cancer, respectively. Although no consensus has been reached regarding the treatment of Siewert type II, several retrospective studies suggested that the optimal treatment strategy includes paraaortic LN dissection. Against this background, a Japanese nationwide prospective trial is being conducted to determine the proportion of LN metastasis in GEJ cancers and to identify the optimal extent of LN dissection in each type.

Chair-side surface treatment method for inducing hydrophilicity in titanium dental implant (치과용 티타늄 임플란트의 골융합 증진을 위한 체어사이드 친수성 표면처리방법)

  • Lee, Jung-Hwan;Jun, Soo-Kyung;Lee, Hae-Hyoung
    • The Journal of the Korean dental association
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    • v.54 no.12
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    • pp.985-995
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    • 2016
  • Titanium (Ti) has been widely used for dental implant due to great biocompatibility and bonding ability against natural alveolar bone. A lot of titanium surface modification has been introduced in dentistry and, among them, methods to introduce micro/nano-roughened surface were considered as clinically approved strategy for accelerating osseointegration of Ti dental implant. To have synergetic effect with topography oriented favors in cell attachment, chair-side surface treatment with reproducibility of micro/nano-topography is introduced as next strategy to further enhance cellular functionalities. Extensive research has been investigated to study the potential of micro/nano-topography preserved chair-side surface treatment for Ti dental implant. This review will discuss ultraviolet, low level of laser therapy and non-thermal atmospheric pressure plasma on Ti dental implant with micro/nano-topography as next generation of surface treatment due to its abilities to induce super-hydrophilicity or biofunctionality without change of topographical cues.

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The Effect of Grouping by Extraversion and Introversion in Paired Think-Aloud Problem Solving Using Problem-Solving Strategy (문제 해결 전략을 사용하는 해결자.청취자 활동에서 내.외향성에 따른 소집단 구성의 효과)

  • Jeon, Kyung-Moon;Kang, Hun-Sik;Noh, Tae-Hee
    • Journal of The Korean Association For Science Education
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    • v.23 no.1
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    • pp.57-65
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    • 2003
  • In this study, the effects of grouping by extraversion and introversion in paired think-aloud problem solving using a four-stage problem-solving strategy emphasizing planning and checking stages were investigated. Prior to the instructions, the students' extraversion/introversion in three high school classes (N=87) were examined, and those classes were randomly assigned to the homogeneous, the heterogeneous, and the control groups. The test scores of the two treatment groups were significantly higher than those of the control group in the problem-solving ability. However, there were no significant differences in learning difficulty and self-efficacy. Although there were no significant differences between the scores of two treatment groups in the subcategories of the perception of treatment, the test scores of extroverts were significantly higher than those of introverts in the perception of performing listener's role, the preference to problem solving strategy, and the preference to paired think-aloud problem solving.

Effects of Strategy Instruction in English Language Teaching: A Meta-analysis (영어교과에서의 전략 지도(Strategy Instruction)의 효과: 메타분석)

  • Lee, Je-Young
    • The Journal of the Korea Contents Association
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    • v.18 no.10
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    • pp.298-305
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    • 2018
  • The objective of this present study was to investigate the overall effects of strategy instruction on Korean students' English language learning. In order to do so, 55 individual experimental results in 46 journal articles were collected, and a meta-analysis was carried out to them. This study also analyzed the results of studies on strategy instruction according to various variables such as school types, treatment periods, and types of dependent variable. The mean effect size of strategy instruction in English language teaching is .536, which means the medium effects in general. No statistically significant differences were found among various moderators and dependent variables. Based on these results, suggestions for further research are discussed.

Strategy of Multistage Gamma Knife Radiosurgery for Large Lesions (큰 병변에 대한 다단계 감마나이프 방사선수술의 전략)

  • Hur, Beong Ik
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.801-809
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    • 2019
  • Existing Gamma Knife Radiosurgery(GKRS) for large lesions is often conducted in stages with volume or dose partitions. Often in case of volume division the target used to be divided into sub-volumes which are irradiated under the determined prescription dose in multi-sessions separated by a day or two, 3~6 months. For the entire course of treatment, treatment informations of the previous stages needs to be reflected to subsequent sessions on the newly mounted stereotactic frame through coordinate transformation between sessions. However, it is practically difficult to implement the previous dose distributions with existing Gamma Knife system except in the same stereotactic space. The treatment area is expanding because it is possible to perform the multistage treatment using the latest Gamma Knife Platform(GKP). The purpose of this study is to introduce the image-coregistration based on the stereotactic spaces and the strategy of multistage GKRS such as the determination of prescription dose at each stage using new GKP. Usually in image-coregistration either surgically-embedded fiducials or internal anatomical landmarks are used to determine the transformation relationship. Author compared the accuracy of coordinate transformation between multi-sessions using four or six anatomical landmarks as an example using internal anatomical landmarks. Transformation matrix between two stereotactic spaces was determined using PseudoInverse or Singular Value Decomposition to minimize the discrepancy between measured and calculated coordinates. To evaluate the transformation accuracy, the difference between measured and transformed coordinates, i.e., ${\Delta}r$, was calculated using 10 landmarks. Four or six points among 10 landmarks were used to determine the coordinate transformation, and the rest were used to evaluate the approaching method. Each of the values of ${\Delta}r$ in two approaching methods ranged from 0.6 mm to 2.4 mm, from 0.17 mm to 0.57 mm. In addition, a method of determining the prescription dose to give the same effect as the treatment of the total lesion once in case of lesion splitting was suggested. The strategy of multistage treatment in the same stereotactic space is to design the treatment for the whole lesion first, and the whole treatment design shots are divided into shots of each stage treatment to construct shots of each stage and determine the appropriate prescription dose at each stage. In conclusion, author confirmed the accuracy of prescribing dose determination as a multistage treatment strategy and found that using as many internal landmarks as possible than using small landmarks to determine coordinate transformation between multi-sessions yielded better results. In the future, the proposed multistage treatment strategy will be a great contributor to the frameless fractionated treatment of several Gamma Knife Centers.

A Convergence Analysis Study on the Awareness and Performance of Physiotherapist's Infection Control Using IPA (IPA를 이용한 물리치료사 감염관리의 인지도 및 수행도에 융복합적인 분석 연구)

  • Kim, Jeong-geon;Kim, Myung-chul;Kim, Hae-in;Lee, Hong-jun
    • Journal of the Korea Convergence Society
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    • v.12 no.11
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    • pp.155-160
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    • 2021
  • This study analyzed the awareness and performance of physical therapists' infection control using IPA. The four areas were divided into handwashing, personal management, Treatment room environment management, and infection control education, and a survey was conducted on awareness and practice. General characteristics were analyzed for frequency, and recognition and performance were analyzed through paired t-test and Pearson's correlation. Handwashing was both high and infection, control education had high performance, but low awareness. The performance of Treatment room environment was high, but the awareness was low, and personal management was both low. Therefore, based on this study, there is a need for a strategy to improve the awareness of infection control education, a strategy to improve performance in the treatment room environment, and a strategy to improve both performance and awareness in Personal management.