• Title/Summary/Keyword: treatment planning

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The Estimation of Bio-kinetic Parameters using Respirometric Analysis (산소이용률을 이용한 생물학적 동력학 계수 추정)

  • Choung, Youn-Kyoo;Kim, Han-Soo;Yoo, Sung-In
    • Journal of Korean Society of Environmental Engineers
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    • v.22 no.1
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    • pp.11-19
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    • 2000
  • In order to predict the performance of biological wastewater treatment plant, the kinetic parameters and stoichiometric coefficient must be known. The theories and experimental procedures for determining the biological kinetic parameters were discussed in this study. Respirometric analysis in the batch reactor was carried out for the experimental assessment of kinetic parameters. A simple procedure to estimate kinetic parameters of heterotrophs and autotrophs under aerobic condition was presented. The difficulties in the interpretation of COD and VSS measurements encouraged the conversion of respirometric data to growth data. Maximum specific growth rate, yield coefficient, half saturation constant and decay rate of heterotrophic biomass were obtained from OUR(Oxygen Uptake Rate) data. Maximum specific growth rate of autotrophic biomass was obtained from the increase of nitrate concentration. The aim of this paper is to estimate the kinetic parameters of heterotrophic and autotrophic biomass by means of the respirometric analysis of activated sludge behavior in the batch reactors. These procedures may be used for the activated sludge modeling with complex kinetic parameters.

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Evaluation of the Development and Reduction Scheme under Implementation Plan of Total Maximum Daily Loads in the Jinwi Watershed (진위천 수계의 수질오염총량제 시행에 따른 지역개발과 삭감계획 평가)

  • Han, Mideok;Ahn, Ki Hong;Ryu, Jichul;Son, Jeeyong;Park, Bae Kyung;Kim, Young Seok
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.6
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    • pp.451-459
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    • 2014
  • The development and reduction scheme under implementation plan of TMDLs were performed in the Jinwi watershed including 8 cities (Gunpo, Yongin, Suwon, Anseong, Osan, Uiwang, Pyeongtaek and Hwaseong) since 2012. Progress of the annual development schemes was faster than the reduction schemes in most of the cities during the planning period. Main load reduction methods included establishment and enlargement of sewage treatment plants, resources of livestock excretions, and introduction of best management practices of non-point source pollution. Especially, reduction load using recycling and composting of livestock excretions comprised 34.1% of all reduction load. It is necessary to implement methodical development and reduction scheme for making of successful performance of TMDLs and water quality improvement in the Jinwi watershed.

Comparative Differential Expressions of Porcine Satellite Cell during Adipogenesis, Myogenesis, and Osteoblastogenesis

  • Jeong, Jin Young;Kim, Jang Mi;Rajesh, Ramanna Valmiki;Suresh, Sekar;Jang, Gul Won;Lee, Kyung-Tai;Kim, Tae Hun;Park, Mina;Jeong, Hak Jae;Kim, Kyung Woon;Cho, Yong Min;Lee, Hyun-Jeong
    • Reproductive and Developmental Biology
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    • v.37 no.4
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    • pp.225-232
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    • 2013
  • Satellite cells were derived from muscular tissue in postnatal pig. Satellite cell is an important to growth and development in animal tissues or organs. However, the progress underlying induced differentiation is not clear. The aim of this study was to evaluate the morphologic and the transcriptome changes in porcine satellite cell (PSC) treated with insulin, rosiglitazone, or dexamethasone respectively. PSC was obtained from postnatal muscle tissue. In study 1, for study the effect of insulin and FBS on the differentiated satellite cells, cells were cultured at absence or presence of insulin treated with FBS. Total RNA was extracted for determining the expression levels of myogenic PAX3, PAX7, Myf5, MyoD, and myogenin genes by real-time PCR. Myogenic genes decreased expression levels of mRNA in treated with insulin. In study 2, in order to clarify the relationship between rosiglitazone and lipid in differentiated satellite cells, we further examined the effect of FBS on lipid accumulation in the presence or absence of the rosiglitazone and lipid. Significant differences were observed between rosiglitazone and lipid by FBS. The mRNA of FABP4 and $PPAR{\gamma}$ increased in rosiglitazone treatment. In study 3, we examined the effect of dexamethasone on osteogenic differentiation in PSC. The mRNA was increased osteoblasotgenic ALP and ON genes treated with dexamethasone in 2% FBS. Dexamethasone induces osteoblastogenesis in differentiated PSC. Taken together, in differentiated PSCs, FABP4 and $PPAR{\gamma}$ increased to rosiglitazone. Whereas, no differences to FBS and lipid. These results were not comparable with previous reports. Our results suggest that adipogenic, myogenic, and osteoblastogenic could be isolated from porcine skeletal muscle, and identify culture conditions which optimize proliferation and differentiation formation of PSC.

A Study on the Evaluation of Service Quality Index for International Airport Using MCJ (MCJ를 이용한 공항서비스 품질지수 평가에 관한 연구)

  • Lee, Seung-Chang;Lee, Gang-Seok
    • Journal of Korean Society of Transportation
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    • v.23 no.1
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    • pp.45-54
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    • 2005
  • The main purpose of this study is located at developing Ominibus Monitoring System(OMS) for the purpose of the internal management, which enable to establish job standards, find out matters to be improved, and appreciate for its treatment in a systematic way. It is through developing subjective or objective estimation tool with use of importance, perceived level, and complex index at international airport by each principal service items, The direction of this study came towards for the purpose of developing a metric analysis tool, utilizing the Quantitative Secondary Data, Analysing Perceived Data through airport user surveys, systemizing the data collection-input-analysis process, making data image according to the graph of results, planning service encounter and endowing control attribution, and ensuring competitiveness at the minimal international standards. It is much important to set up a pre-investigation plan on the base of existent foreign literature and actual inspection to international airport. Two tasks have been executed together on the base of this pre-investigation; one is developing subjective estimation standards for departing party, entering party, and airport residence and the other is developing objective standards as complementary methods. The study has processed for the monitoring services at airports regularly and irregularly through developing software system for operating standards after ensuring credibility and feasibility of estimation standards with substantial and statistical way.

A Study on Dose Distribution around Fletcher-Suit Colpostat Containing Cs-137 Source by a Computer (컴퓨터 의한 Fletcher-Suit Colpostat 주변의 Cs-137의 선량분포에 관한 연구)

  • Kang Wee-Saing
    • Radiation Oncology Journal
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    • v.7 no.2
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    • pp.305-311
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    • 1989
  • Fletcher-Suit colpostat has an internal structure to reduce dose to bladder and rectum. Some programs were developed to calculate dose at any point in water in three dimension around the colpostat containing Cs-137 tube, to find the shielding effect to dose by the internal structure, and to draw isodose curves and iso-shielding effect curves. Computer was an IBM compatible AT with EGA card and language was MS-Basic V6.0, Material, shape and geometry of the strucure, tube and colpostat were considered in algorithm for calculation of dose. Dose rates per unit mg. Ra. eq. in water calculated by a program were stored in auxiliary memory devices and retrieved in another programs. Isodose curves on medial side shrinked. Dose distribution was not symmetric about a transverse axis bisecting the colpostat. Reduction of dose was more excessive on top side than on bottom. Iso-shielding effect curve showed that the shielding effect was higher on top side than on bottom, and that there was shielding effect over almost all area of medial side. Such results were related to both shifted position of tube in the colpostat and asymmetric distribution of active source in the tube. Maximum of shielding effect was $49\%$ on top side and $44\%$ on bottom side. The direction of iso-shielding effect curve was generally radial from the center of active source. In treatment planning using Fletcher-Suit colpostat, the internal structure should be considered to find precise doses to bladder and rectum, etc.

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Dosimetric advantages and clinical outcomes of simultaneous integrated boost intensity-modulated radiotherapy for anal squamous cell carcinoma

  • Sakanaka, Katsuyuki;Itasaka, Satoshi;Ishida, Yuichi;Fujii, Kota;Horimatsu, Takahiro;Mizowaki, Takashi;Sakai, Yoshiharu;Hiraoka, Masahiro
    • Radiation Oncology Journal
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    • v.35 no.4
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    • pp.368-379
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    • 2017
  • Purpose: The purpose of this study was to explore the dosimetric difference between simultaneous integrated boost intensity-modulated radiotherapy (SIB-IMRT) and three-dimensional conformal radiotherapy (3DCRT), and the clinical outcomes of anal squamous cell carcinoma (ASCC) chemoradiotherapy featuring SIB-IMRT. Materials and Methods: This study included ten patients with ASCC who underwent chemoradiotherapy using SIB-IMRT with 5-fluorouracil and mitomycin C. SIB-IMRT delivered 54 Gy to each primary tumor plus metastatic lymph nodes and 45 Gy to regional lymph nodes, in 30 fractions. Four patients received additional boosts to the primary tumors and metastatic lymph nodes; the median total dose was 54 Gy (range, 54 to 60 Gy). We additionally created 3DCRT plans following the Radiation Therapy Oncology Group 9811 protocol to allow dosimetric comparisons with SIB-IMRT. Locoregional control, overall survival, and toxicity were calculated for the clinical outcome evaluation. Results: Compared to 3DCRT, SIB-IMRT significantly reduced doses to the external genitalia, bladder, and intestine, delivering the doses to target and elective nodal region. At a median follow-up time of 46 months, 3-year locoregional control and overall survival rates were 88.9% and 100%, respectively. Acute toxicities were treated conservatively. All patients completed radiotherapy with brief interruptions (range, 0 to 2 days). No patient experienced ${\geq}grade$ 3 late toxicity during the follow-up period. Conclusion: The dosimetric advantages of SIB-IMRT appeared to reduce the toxicity of chemoradiotherapy for ASCC achieving high locoregional control in the extended period.

A Study on the Standardization In Diagnostic Criteria on Jung-Pung (中風) (중풍진단(中風診斷)의 표준화방안(標準化方案) 연구(硏究))

  • Shim, Hyun-Ki;Park, Se-Ki;Kim, Dong-Woo;Jun, Chan-Young;Han, Yang-Hee;Park, Jong-Hyeong
    • The Journal of Internal Korean Medicine
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    • v.18 no.2
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    • pp.332-357
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    • 1997
  • The purpose of study is for the defining the diagnostic criteria of Jung-Pung (中風) which are confused or unclear partially or Oriental Medicine. The results were obstained as follows ; 1. The Diagnosis of Jung-Pung (中風) can be accomplished by the name of disease, symptomatic classification, Byun-Jeung (辨證), stage, assessment of neurological deficit. 2. The various expressive way on the names of Jung-Pung (中風) can be unified as Jung-Pung (中風). 3. The symptomatic classification of Jung-Pung (中風) can be Jung-Kyung-Rak (中經絡) and Jung-Jang-Bu (中臟腑) by unconsciousness. 4. The subclassification of Jung-Kyung-Rak(中經絡) is Kanyangpokhang Punghwa sangyo (肝陽暴亢 風火上擾證), PungDamErHyul BiJoMaecRak (風痰瘀血 痺阻脈絡證), DamYeolBusil PoongDamSangYo (痰熱腑實 風痰上擾證), KiHerhyulEr (氣虛血瘀證), YeumHer PungDong (陰虛風動證) and Jung-Jang-Bu (中臟腑) is PungHwa SangYo CheongGeu (風火上擾淸竅證), DamSeupMongSac ShimSin (痰濕蒙塞心神證), DamYeolNaeFe ShimGeu (痰熱內閉心竅證), WonKiFaeTal ShimSinChakRan(元氣敗脫心神錯亂證) 5. The classification of stages can be divided as stroke stage, convalescent stage, complicated deficit stage. 6. In Oriental Medicine there were few assessment methods of neurological deficit. Therefore we need to develop new assessment system or modification of Western Medicine. The Standardization in the diagnosis of Jung-Pung (中風) has not been well established, even though we had have many clinical experiences. So it is necessary to make a accurate diagnosis that can be done by multiple diagnostic assessment. Therefore the accurate diagnosis of Jung-Pung (中風) can be done by 5 factors, they are the name of diagnosis, symptomatic classification, Byun-Jeung (辨證), stage, the assessment of neurological dificit. And it can be applied in the planning of treatment.

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Medical Care Utilization Status and Associated Factors with Extended Hospitalization of Psychiatric Patients in Korea (우리나라 정신질환자의 의료이용 현황과 장기입원 관련 요인)

  • Suh, Soo-Kyung;Kim, Yoon;Park, Jong-Ik;Lee, Myung-Soo;Jang, Hong-Suk;Lee, Sun-Young;Lee, Jin-Seok
    • Journal of Preventive Medicine and Public Health
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    • v.42 no.6
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    • pp.416-423
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    • 2009
  • Objectives : This study was performed to examine medical care utilization of psychiatric patients and to explore patients' characteristics associated with extended hospitalization. Methods : Data were extracted from information of Korean Health Insurance Review and Assessment Service. All data associated with admission and outpatient clinic visit were analysed by patient characteristics. We selected first psychiatric admission patients who diagnosed mental and behavioral disorders due to use of alcohol (main disease code: F10), schizophrenia and related disorders (F20-29) and mood disorders (F30~33) from January to June 2005. We analysed status of admission, mean length of stay, regular access to outpatient clinic and rates of extended hospitalization during 3 years. Bivariate and multivariate analyses were conducted to identify factors associated with extended hospitalization. Results : The number of psychiatric patients during the first six month of 2005 was 30,678. The mean length of stay was longest for schizophrenia and related disorders but shortest for mood disorders. Patients who experienced an extended hospitalization were 18.8% of total subjects. An extended hospitalization was more common in schizophrenia and related disorders than other diagnostic groups. The factors associated with the extended hospitalization were age, sex, diagnostic group, type of insurance and medical care utilization groups. Conclusions : The study indicates the problem of an extended hospitalization for psychiatric patients in Korea. It is suggested that variations in rates of extended hospitalization among medical care utilization group may need an active early intervention system in psychiatric treatment service. Particular attention needs to be devoted to planning and funding for reducing extended hospitalization.

Micrografting and Heat Treatment Combination for Eliminating Virus of CTV-infected Citrus (CTV 바이러스 보균 감귤나무로부터 열처리와 경정접목을 통한 바이러스 제거)

  • Chae, Chi Won;Yun, Su Hyun;Park, Jae Ho;Hyun, Jae Wook;Koh, Sang Wook;Lee, Dong Hoon
    • Journal of Life Science
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    • v.23 no.2
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    • pp.267-272
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    • 2013
  • This study was conducted to eliminate viruses from citrus-infected plants using micrografting and thermotherapy. Six citrus cultivars including a 'Setoka' hybrid were used as plant sources. The TAS-ELISA technique demonstrated that several plants were CTV positive. However, no CTV symptoms were detected in plants obtained from shoots and treated at a high temperature of $40^{\circ}C$ during the day and night and micrografted for two weeks with old trifoliate orange rootstock in vitro. Indexing of CTV, SDV, and CTLV for RT-PCR analysis of the eleven citrus seedlings, including 'Setoka', 'Samdajosang', 'Pungkwang', 'Shiranuhi', and 'Ehimekashi dai28go' was virus free following the micrografting and thermal therapy.

A Study on Emergency Evacuation Route Planning and USN-Based Induction Activities of Correctional Facilities (교정시설의 비상시 피난경로계획 및 USN기반 대피유도활동에 관한 연구)

  • Park, Joo-Hyung;Park, Jong-Hyun
    • Fire Science and Engineering
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    • v.25 no.2
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    • pp.39-46
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    • 2011
  • In correctional facilities with majority of occupants in custody, the safe evacuation guide without getaway accidents should be very important due to complexity in escape paths. Fire causes are various in correctional facilities, for example, arson fire is a major cause in mental treatment facilities, however, old facilities or carelessness of flammable materials consist of fire causes in jail facilities. Both types of correctional facilities are the same in terms of many casualties from the fire cases. The thesis focus on escape paths and evacuation guide plans on the basis of analysis on fire cases and structural vulnerability, and then an electronic unlocking system is concededly installed for safe evacuation of occupants in custody without getaway accidents. Especially, the effect of the electronic unlocking system is going to be analyzed on the basis of RSET (required safe egress time) in order to realize for the occupants to evacuate safely to the front yard in case of emergency. In conclusion, if electronic security allowed system with USN (Ubiquitous Sensor Networks) technology should be installed in multi-storey correctional buildings, it is proposed that the occupants in custody might be a guided safely without getaway trials.