• 제목/요약/키워드: treatment planning

검색결과 1,821건 처리시간 0.028초

Patterns of recurrence after radiation therapy for high-risk neuroblastoma

  • Jo, Ji Hwan;Ahn, Seung Do;Koh, Minji;Kim, Jong Hoon;Lee, Sang-wook;Song, Si Yeol;Yoon, Sang Min;Kim, Young Seok;Kim, Su Ssan;Park, Jin-hong;Jung, Jinhong;Choi, Eun Kyung
    • Radiation Oncology Journal
    • /
    • 제37권3호
    • /
    • pp.224-231
    • /
    • 2019
  • Purpose: To investigate the patterns of recurrence in patients with neuroblastoma treated with radiation therapy to the primary tumor site. Materials and Methods: We retrospectively analyzed patients with high-risk neuroblastoma managed with definitive treatment with radiation therapy to the primary tumor site between January 2003 and June 2017. These patients underwent three-dimensional conformal radiation therapy or intensity-modulated radiation therapy. A total of 14-36 Gy was delivered to the planning target volume, which included the primary tumor bed and the selected metastatic site. The disease stage was determined according to the International Neuroblastoma Staging System (INSS). We evaluated the recurrence pattern (i.e., local or systemic), progression-free survival, and overall survival. Results: A total of 40 patients with high-risk neuroblastoma were included in this study. The median patient age was 4 years (range, 1 to 11 years). Thirty patients (75%) had INSS stage 4 neuroblastoma. At the median follow-up of 58 months, there were 6 cases of local recurrence and 10 cases of systemic recurrence. Among the 6 local failure cases, 4 relapsed adjacent to the radiation field. The other 2 relapsed in the radiation field (i.e., para-aortic and retroperitoneal areas). The main sites of distant metastasis were the bone, lymph nodes, and bone marrow. The 5-year progression-free survival was 70.9% and the 5-year overall survival was 74.3%. Conclusion: Radiation therapy directed at the primary tumor site provides good local control. It seems to be adequate for disease control in patients with high-risk neuroblastoma after chemotherapy and surgical resection.

양파 연작지의 분홍색뿌리썩음병 방제를 위한 담수처리 효과 (Influence of Soil Flooding on Control of Pink Root Disease in Onion Crop)

  • 문진성;이종태;하인종;황선경;송원두;천미건;이찬중
    • 식물병연구
    • /
    • 제13권2호
    • /
    • pp.104-109
    • /
    • 2007
  • 양파 연작지 토양의 담수기간에 따른 분홍색뿌리썩음병의 방제효과, 양파의 생육 및 수량을 조사한 결과 토양병원균의 밀도변화는 담수기간이 길수록 균밀도의 감소효과가 뚜렷하여 처리 후 90일에는 무담수에 비해 $1/2{\sim}1/3$ 수준으로 감소하였지만 양파 재배후 균밀도는 담수직후 보다는 전반적으로 증가하는 경향을 보였다. 양파 육묘상 담수처리에 의한 분홍색뿌리썩음병의 방제효과는 담수 60일 이상 처리에서 $93.5{\sim}99.2%$였고, 뿌리이병율도 무담수에 비해 $1/11{\sim}1/18$ 수준으로 크게 감소하였다. 양파 재배포장에서의 발병율 또한 담수 60일 이상 처리에서 5% 미만으로 크게 감소하였다. 양파의 구중과 상품수량은 무담수에 비해 담수처리에서 증가되었으며, 담수기간이 길어질수록 대구의 비율이 늘어나는 경향을 보였다. 이와 같이 양파 분홍색뿌리썩음병이 심하게 발생하고 있는 연작지에 양파를 정식하기 전에 담수처리를 할 경우, 적어도 2년간, 60일 이상 담수처리를 하였을 때 효과적으로 분홍색뿌리썩음병균의 밀도와 병발생을 경감시킬 수 있으며, 정상적인 양파 육묘 및 생육에 의한 구비대로 수량 증수효과가 클 것으로 판단된다.

Nasal Anthropometry on Facial Computed Tomography Scans for Rhinoplasty in Koreans

  • Moon, Kyung Min;Cho, Geon;Sung, Ha Min;Jung, Min Su;Tak, Kyoung Seok;Jung, Sung-Won;Lee, Hoon-Bum;Suh, In Suck
    • Archives of Plastic Surgery
    • /
    • 제40권5호
    • /
    • pp.610-615
    • /
    • 2013
  • Background Cephalometric analysis is essential for planning treatment in maxillofacial and aesthetic facial surgery. Although photometric analysis of the Korean nose has been attempted in the past, anthropometry of the deeper nasal structures in the same population based on computerized tomography (CT) has not been published. We therefore measured three anthropometric parameters of the nose on CT scans in our clinical series of patients. Methods We conducted the current retrospective study of a total of 100 patients (n=100) who underwent a CT-guided radiological measurement at our institution during a period ranging from January of 2008 to August of 2010. In these patients, we took three anthropometric measurements: the nasofrontal angle, the pyramidal angle, and the linear distance between the nasion and the tip of the nasal bone. Results The mean nasofrontal angle was $131.14^{\circ}$ in the male patients and $140.70^{\circ}$ in the female patients. The mean linear distance between the nasion and the tip of the nasal bone was 21.28 mm and 18.02 mm, respectively. The mean nasal pyramidal angle was $112.89^{\circ}$ and $103.25^{\circ}$ at the level of the nasal root, $117.49^{\circ}$ and $115.60^{\circ}$ at the middle level of the nasal bone, and $127.99^{\circ}$ and $125.04^{\circ}$ at the level of the tip of the nasal bone, respectively. Conclusions In conclusion, our data will be helpful in the preparation of silicone implants for augmentation and/or corrective rhinoplasty in ethnic Korean people.

비소세포폐암의 방사선 치료기법간의 선량분포의 비교 (Comparison of Dose Distribution between the Techniques of Non-small Cell Lung Cancer)

  • 이승철;김영재;장성주
    • 한국방사선학회논문지
    • /
    • 제10권4호
    • /
    • pp.233-239
    • /
    • 2016
  • 방사선 치료시 최근 많이 쓰이고 있는 IMRT, Tomotherapy, mArc(modulation arc therapy)의 치료법을 선량적인 측면에서 상호 비교하고자 한다. 비소세포성 폐암의 환자를 대상으로 하여 치료계획용적에 58.0 Gy를 처방선량을 기준으로 설정하였으며 주변 정상장기는 척수, 식도, 간을 설정 하였다. PTVmean는 mArc의 경우 57.60 Gy, Tomotherapy가 61.04 Gy, IMRT는 58.95 Gy이었다. 식도(Esophagus)의 평균선량은 mArc가 2.84 Gy였고, Tomotherapy가 5.14 Gy, IMRT가 1.84 Gy로 나타났다. 간(Liver)은 mArc는 19.44 Gy, Tomotherpy가 12.22 Gy, IMRT는 21.97 Gy이었고 척수(Spinal Cord)은 mArc 5.72 Gy, Tomotherapy가 7.08 Gy, IMRT는 6.15 Gy로 측정되었다. 또한, 선량포함도와 선량체적곡선 등의 자료를 관찰해 본 결과 mArc와 Tomotherapy 그리고 IMRT의 결과와 현저한 차이를 보이지는 않았다. 하지만, 본 연구는 폐암이라는 질환으로 한정하였었고 실험군의 수가 적은 단점을 가지고 있으므로 좀 더 많은 질환과 환자를 대상으로 연구를 폭넓게 진행 한다면 환자 맞춤형 치료기법을 개발하여 적용될 것으로 사료된다.

부산시 환경용량평가에 관한 연구 (Environmental Capacity Assessment of Busan City)

  • 황경엽;황인성;이순규;조승우;오광중
    • 환경영향평가
    • /
    • 제15권1호
    • /
    • pp.79-92
    • /
    • 2006
  • Environmental capacity assessment of Busan city was conducted to provide basis for planning on sustainable development and growth of the city. Using Onish model, assessment was carried out on amenities and service facilities for the citizens of Busan city. Ecological Footprint model was used to judge if the city exceeds the its environmental capacity and to estimate the extent of the excess if it exists. The analysis using Onish model revealed that the citizens of Busan city are generally well supported by the infrastructure and service facilities of the city. Water treatment and supply facilities have enough capabilities to support the city, whereas the relatively low rate of sanitary sewer supply (78%) suggests the need for further improvement in the wastewater area. The capacities of sanitary landfills are found sufficient enough to support the city for the next 10 years. The high value for the line length served per capita in the subway sector hints on certain inconvenience of commuters. All the air quality indicators meet the Korean and WHO standards except for $NO_2$. The ecological footprint model analysis produced EF indicators for Busan city of 3.04 ha/person and 2.54 ha/person for the years of 1993 and 2003, respectively. The decrease of the indicator from 1993 to 2003 is mainly due to the incorporation of Gijang area by Busan city in 1995, suggesting the importance of the ecologically productive area in the evaluation using this model. The analysis on the ecological deficit that is based on ecologically productive land shows that the consumption by Busan city exceeds its ecologically available production by 19,600% as of 2003. The area needed to support the consumption of Busan city in 2003 is 123 times as large as the present area of Busan city, which is substantially lower than the multiplier (742) obtained for Seoul city in 1997 but is higher than those observed for Chongju city (71 in 1999) and Ulsan city (39 in 2001).

국내 석탄재 재활용 확대 방안 연구 (Studies on Expanding Application for the Recycling of Coal Ash in Domestic)

  • 조한나;맹준호;김은영
    • 환경영향평가
    • /
    • 제26권6호
    • /
    • pp.563-573
    • /
    • 2017
  • 매년 화력발전소에서 약 800톤이상 되는 석탄재가 발생되고 있다. 발생되는 석탄재 중 재활용되고 남은 석탄재는 회처리장에 매립되고 있다. 현재 회처리장 용량에는 한계가 있고, 석탄재 매립으로 인한 환경영향의 우려로 회처리장 신규 확보도 어려운 상황이다. 환경영향 최소화라는 측면에서 석탄재 재활용 및 유효이용이 향후 장기적 국가적으로 시급하게 해결해야 할 문제로 인식되고 있다. 따라서, 본 연구는 국내 석탄재 재활용 확대를 가로막고 있는 문제점을 분석하여 해외 사례를 바탕으로 친환경적 국토관리와 자원순환사회를 위한 석탄재 재활용 확대 방안을 제안 하고자 하였다. 국내 석탄재 재활용 확대 방안은 다음과 같다. 첫째, 석탄재를 재활용 할 수 있는 법적 근거를 마련하는 것이다. 이를 위해서는 환경성 예측 평가에 대한 기법과 기준 및 체계 개발이 필요하다. 둘째, 이해관계자들의 인식 전환을 유도하는 것이다. 석탄재의 환경 안전성에 대한 연구 및 홍보가 필요하며 이해관계자들의 적극적인 의사소통 및 정보 제공이 필요하다. 셋째, 석탄재 재활용을 활성화 할 수 있는 실제적인 지원방안이 필요하다. 정책방안으로는 석탄재 처리비 지원, 석탄재 공급센터 설치 등이 있다.

주관적인 치아에 대한 인식 및 만족도와 자아존중감과의 관련성 (Relationships between subjective teeth awareness and satisfaction on self-esteem)

  • 정은서;이경희
    • 디지털융복합연구
    • /
    • 제14권2호
    • /
    • pp.315-324
    • /
    • 2016
  • 본 연구는 치아가 외모에 미치는 영향에 대한 인식 및 자신의 치아 만족도, 주관적인 치아에 대한 인식과 자아존중감에 대해 살펴보고, 이들의 관련성에 대해 조사함으로써 향후 치아 미용 관련 환자의 진료에 필요한 기초자료를 제공하고자 하였다. 2015년 5월부터 8월까지 서울 및 경기지역에 거주하는 일반인 320명의 자료를 수집하여 이중 응답이 미흡한 18부를 제외한 302(94.38%)부를 분석하여 다음과 같은 결과를 얻었다. 적합된 회귀모형은 통계적으로 유의하였으며(p<0.001), 모형 설명력은 23.4%로 나타났으며, 선정된 독립변수 중 학력(대졸 이상)과 치아가 외모에 미치는 영향에 대한 인식, 주관적인 치아에 대한 인식은 자아존중감에 통계적으로 유의한 영향을 미치는 것으로 나타났다. 이상의 연구결과 주관적인 치아에 대한 인식이 증가할수록 자아존중감을 향상되는 것으로 나타나 치과를 내원하는 환자들의 구강건강을 향상시킬 수 있도록 이와 관련된 구강보건교육을 시행하고, 치아의 색이나 배열 등을 개선할 수 있는 적극적인 의료서비스를 제공하여 자신감과 만족감을 더 고취시킬 수 있어야 할 것으로 사료된다.

노인에서 성대 용종의 후두 미세수술 후 음성검사 결과 (Result of Voice Analysis after Laryngeal Microsurgery for Vocal Polyp in Elderly)

  • 최정임;여장옥;진성민;이상혁
    • 대한후두음성언어의학회지
    • /
    • 제22권1호
    • /
    • pp.47-51
    • /
    • 2011
  • Background and Objectives: Vocal polyps arc one of the most frequent benign laryngeal diseases. They arc usually found at the midpoint of the vocal fold. They are mainly caused by vocal overuse. Vocal polyps arc usually removed surgically. Generally, age-related changes to speech are attributed to change in anatomy and physiology of the speech mechanism. These changes result in increased variability in the acoustic properties of speech with age. Still, not 'all studies of age-related changes in speech have taken differences between the young group and adult group after laryngeal microsurgery into account. The aim of this investigation was to compare improvement of acoustic analysis in young patients and elderly patients with vocal polyps, before and after the laryngeal microsurgery. Materials and Method: One hundred and twenty-eight patients who underwent laryngeal microsurgery for vocal polyps from 2008 through 2011 were reviewed retrospectively. 105 of the 128 patients under age 60 were classified as adult group (AG), and remaining 23 patients as elderly group (EG). The speech of AG and EG were evaluated before and after surgery for identification of differences for age group across measures of fundamental frequency (F0), Jitter, Shimmer and Maximum phonation time (MPT). Results: There were not significant differences between two groups for improvement of F0, Jitter, Shimmer, NHR, and MPT before and after surgery. The findings suggest that elderly group compares quite well with adult group in effectiveness of surgery. However, comparison between elderly group and young group (Age under 40) there was significant difference of improvement in Jitter and Shimmer. Conclusion: In general, the results of the present research showed significant improvement in vocal quality after phonosurgery of vocal polyp in both elderly and adult group. However, comparison of improvement between elderly group and young group, there were significant differences of improvement in jitter and shimmer. Therefore, in treatment planning of elderly group, we should consider age related changes of vocal cord.

  • PDF

조선소 근로자들의 구강보건교육경험 유무에 따른 구강보건인식의 차이 (Relationship of Oral Health Education Experience to Oral Health Awareness among Shipbuilding Workers)

  • 김은주;우승희
    • 한국콘텐츠학회논문지
    • /
    • 제12권7호
    • /
    • pp.240-246
    • /
    • 2012
  • 작업공정 특성상 작업환경이 열악하다고 판단되는 조선소 근로자의 구강보건증진과 구강보건교육계획, 산업구강보건정책 및 제도 개선에 기여하고자 편의표본추출법에 의해 선정한 전남 지역 조선소 및 협력업체 10곳에 근무하는 조선소 근로자를 대상으로 구강보건교육 경험에 따른 구강보건인식의 차이를 알아보기 위하여 조사한 결과는 다음과 같다. 연구대상자 310명 중 구강보건교육경험이 없는 근로자는 89.4%이었고, 구강보건교육 무경험자는 구강보건 지식정도, 인식정도, 관심정도, 중요정도가 낮은 것으로 나타났으며 구강보건 지식정도, 인식정도, 관심정도, 중요정도 간에는 상관관계가 높은 것으로 나타났다. 구강보건교육 무경험자가 구강보건교육을 받지 못하는 이유는 기회가 없었기 때문인 것으로 나타났고 선호하는 교육내용은 치아우식증예방 및 치료법, 선호하는 교육방법은 치의사의 강연인 것으로 나타났으며 구강보건교육 경험이 있는 근로자일수록 구강보건교육 경험이 없는 근로자보다 구강보건교육에 참여할 의향이 있는 것으로 나타났다.

Distribution and phenotypes of hemifacial microsomia and its association with other anomalies

  • Yang, Il-Hyung;Chung, Jee Hyeok;Yim, Sunjin;Cho, Il-Sik;Lim, Seung-Weon;Kim, Kikap;Kim, Sukwha;Choi, Jin-Young;Lee, Jong-Ho;Kim, Myung-Ji;Baek, Seung-Hak
    • 대한치과교정학회지
    • /
    • 제50권1호
    • /
    • pp.33-41
    • /
    • 2020
  • Objective: To investigate the distribution and phenotypes of hemifacial microsomia (HFM) and its association with other anomalies. Methods: This study included 249 Korean patients with HFM, whose charts, photographs, radiographs, and/or computed tomography scans acquired during 1998-2018 were available from Seoul National University Hospital and Dental Hospital. Prevalence according to sex, side involvement, degree of mandibular deformity, compensatory growth of the mandibular body, and Angle's classification, and its association with other anomalies were statistically analyzed. Results: Prevalence was not different between male and female patients (55.0% vs. 45.0%, p > 0.05). Unilateral HFM (UHFM) was more prevalent than bilateral HFM (BHFM) (86.3% vs. 13.7%, p < 0.001). Although distribution of the Pruzansky-Kaban types differed significantly in patients with UHFM (I, 53.0%; IIa, 18.6%; IIb, 24.7%; III, 3.7%; p < 0.001), no difference was observed in occurrence between the right and left sides (52.6% vs. 47.4%, p > 0.05). Among patients with BHFM, prevalence of different Pruzansky-Kaban types on the right and left sides was greater than that of the same type on both sides (67.6% vs. 32.4%, p < 0.05). Despite hypoplasia of the condyle/ramus complex, compensatory growth of the mandibular body on the ipsilateral side occurred in 35 patients (14.1%). Class I and II molar relationships were more prevalent than Class III molar relationships (93.2% vs. 6.8%, p < 0.001). Forty-eight patients (19.3%) had other anomalies, with 50.0% and 14.4% in the BHFM and UHFM groups (p < 0.001). Conclusions: Patients with HFM require individualized diagnosis and treatment planning because of diverse phenotypes and associations with other anomalies.