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주기적인 운동이 뒷다리 부유에 의해 유발된 쥐의 뒷다리를 위축경감에 미치는 영향 (Effect of Periodic Low-intensity Exercise on the Hindlimb Muscles of Hindlimb Suspended Rats)

  • 최명애;신기수
    • Journal of Korean Biological Nursing Science
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    • 제1권1호
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    • pp.71-85
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    • 1999
  • The purpose of this study was to determine the effect of periodic low-intensity exercise during hindlimb suspension on the mass, relative weight, myofibrillar protein content in soleus, plantaris and gastrocnemius muscles. To examine the effectiveness of periodic low-intensity exercise on mass, and myofibrillar protein content of hindlimb muscles, adult female Wistar rats were suspended(HS) and half of these rats walked on a treadmill for 45min/day(15 min every 4h) at 5m/min and a $15^{\circ}$ grade(HS-EX). Soleus wet weight was 33.51% significantly smaller(p<0.005) and relative soleus weight of hindlimb suspended rats was 31.96% smaller(p<0.005) compared with those of control rats following seven days of hindlimb suspension. Plantaris wet weight was 7.5% smaller(p<0.01) and relative plantaris weight was 11.83% smaller(p<0.05) compared with those of control rats following seven days of hindlimb suspension. Gastrocnemius wet weight was 11.31% significantly smaller(p<0.005) and relative gastrocnemius weight was 17.13% significantly smaller(p<0.005) compared with those of control rats following seven days of hindlimb suspension. Soleus wet weight while increased by relative soleus weight increased by 25.13%, 27.59% each through periodic low intensity exercise during hindlimb suspension(p<0.05, p<0.05). Plantaris wet weight and relative plantaris weight increased by 1.04%, 10.98%(p<0.05) each, and gastrocnemius wet weight and relative gastrocnemius weight increased by 1.98%, 12.02%(p<0.05) each through periodic low intensity exercise during hindlimb suspension. Wet weight of soleus, plantaris and gastrocnemius in HS-EX rats did not recover to control level. Myofibrillar protein content of soleus, plantaris and gastrocnemius was 48.24%, 40.85% and 37.33% significantly smaller(p<0.005) respectively compared with those of control rats following seven days of hindlimb suspension. Myofibrillar protein content of soleus, plantaris and gastrocnemius increased by 40.68%, 25.07% and 17.93%(p<0.005) each through periodic low intensity exercise during hindlimb suspension. Myofibrillar protein content of soleus, plantaris, and gastrocnemius in HS-EX rats did not recover to control level. The results suggest that periodic low intensity exercise can attenuate hindlimb muscle atrophy induced by hindlimb suspension.

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운동형태에 따른 중년여성의 신체구성과 혈중지질의 변화 (Effects of aerobic and combined exercise on body composition and blood lipid in the middle-aged women)

  • 김용철;김영수;양정옥;이범진;이중숙
    • Journal of the Korean Data and Information Science Society
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    • 제24권6호
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    • pp.1241-1251
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    • 2013
  • 이 논문의 연구목적은 운동형태에 따라 중년여성의 신체구성과 혈중지질에 미치는 영향을 규명하기 위한 것이다. 연구대상은 40 50대 중년여성으로 유산소운동집단 8명, 복합트레이닝집단 8명 두 그룹으로 나누었으며, 12주간의 운동프로그램을 실시하였다. 운동강도는 주4회, 1회 70~90분, HRmax 60%~75%, 1RM 60%~80%로 점진적으로 증가시켰다. 자료처리는 Windows 용 SPSS ver. 21.0 통계 프로그램을 사용하여 평균과 표준편차 등을 산출하고, 비모수통계분석 방법인 윌콕슨 부호순위검정과 윌콕슨 순위합검정을 통해 그룹별 사전-사후 평균차와 변화량에 대한 그룹간 차이를 검정하였다. 연구결과를 살펴보면, 먼저 각 집단별 사전-사후 평균차에서는 복합운동 집단의 BMI, 체지방량, 그리고 중성지방에서만 통계적으로 유의한 차이가 나타났다. 또한 변인별 사전-사후 변화량에 대한 두 집단간의 차이 검정에서는 체지방량에서만 통계적으로 유의한 차이가 나타났다. 부가적으로 통계적 유의성은 검증되지 않았지만 각 별인별 사전-사후 평균 변화에 대한 기술통계를 살펴보면 복합운동이 유산소운동에 비해 상대적으로 더 효과적일 수 있다는 것을 알 수 있다.

밥 식이와 빵 식이가 지구성 운동 후 혈중 중성지방, 인슐린 및 그렐린에 미치는 영향 (Effects of Rice Diet and Bread Diet on Plasma Triglyceride, Insulin and Ghrelin Level after Endurance Exercise)

  • 유동훈;하태열;안지윤;정현령;강호율
    • 한국식품영양과학회지
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    • 제41권8호
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    • pp.1112-1117
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    • 2012
  • 본 연구는 밥 식이와 빵 식이가 지구성 운동 후 중성지방, 그렐린, 인슐린, 혈당, 유리지방산, 지방과 탄수화물 산화율을 조사하여 두 식이의 차이점을 분석하였다. 중성지방은 지구성 운동 시 두 식이 간에 유의한 차이는 나타나지 않았으며 운동 후 회복기에서 중성지방은 밥 식이가 빵 식이보다 유의하게 감소하였다. 인슐린과 혈당에서도 밥 식이는 빵 식이보다 유의하게 감소된 결과를 나타냈다. 밥 식이와 빵 식이의 유리지방산과 지방 산화율은 운동과 운동 후 회복기에서 통계적 유의한 차이는 나타나지 않았지만 밥 식이가 빵 식이보다 다소 높은 경향을 나타내었다. 운동을 병행한 두 식이 간 비교에서 밥 식이가 중성지방 감소, 낮은 혈당 반응, 인슐린 민감성 향상의 결과가 나타났다. 이상의 결과를 종합할 때 일회성 운동이지만 서구의 주식인 빵 식이보다 우리의 주식인 밥 식이의 섭취가 운동과 병행하였을 경우 심혈관질환 예방 효과의 가능성을 볼 수 있었다.

심장재활 프로그램이 허혈성 심장환자의 건강행위 이행, 심혈관 기능 및 삶의 질에 미치는 효과 (The Effects of a Cardiac Rehabilitation Program on Health Behavior Compliance, Cardiovascular Function, and Quality of Life for the Patients with Ischemic Heart Disease)

  • 조현숙;김광주
    • 대한간호학회지
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    • 제30권3호
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    • pp.560-570
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    • 2000
  • This study is aimed at developing a cardiac rehabilitation program and enlightening the effects of the program on patient's health behavior compliance, cardiovascular functional capacity, and quality of life. Using a quasi-experimental approach the nonequivalent control group pretest - posttest design was accepted for this study. The subjects of this study consisted of 55 patients with ischemic heart disease at the Cardiac Center of 'G' Hospital located in Inchon from May 1, 1998 to April 30, 1999. The patients were divided into two groups: the experimental group, which participated in the cardiac program with 30 patients and 25 patients of a control group were not involved in the program. There were two phases in the cardiac rehabilitation program: the first phase was a team approach education. It focused on reducing the risk of ischemic heart problems. The second phase was individual training by using a home based exercise program, which was comprised of 8 weeks, three sessions per week, 40-60 minutes per session, and followed by consultation. Every session involved 20-40 minutes of aerobic exercise at 40-60% of heart rate reserve, 11∼13 RPE and 10 minutes of warm-up and 10 minutes of cool-down exercises. The experimental tools for the study were the health behavior compliance scale developed by Lee, Yoon-hee (1992), and quality of life scale developed by McGirr et al.(1990). RPPsubmax were measured by the treadmill. The collected data was processed by SPSS and analyzed by χ²test and t-test. The results of this study were as follows: 1. The health behavior compliance in experimental group was significantly increased (t=5.091, p=.000) when compared to the control group. 2. RPPsubmax also decreased significantly in the experimental group when compared to the control group(t=-2.109, p=.040). 3. The quality of life significantly improved in the experimental group (t=3.853, p=.000) as compared to the control group. As the above results of this study revealed, the effectiveness of the cardiac rehabilitation program of the study was confirmed. It increased the health behavior compliance for reducing the risk of further coronary events, enhanced the cardiovascular functional capacity, and eventually improved the patient's quality of life.

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Effects of Alcohol Intake on Body Fluid Balance and Fat Mobilization After Exercise Induced Dehydration

  • Park, Hyun-Jeong;Bae, Yoon-Jung;Lee, Joo-Hyung;Lee, Dae-Taek
    • Nutritional Sciences
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    • 제9권2호
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    • pp.124-130
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    • 2006
  • To examine the effects of alcohol consumption on body fluid restoration and fat mobilization following exercise induced dehydration, nine healthy collegiate men ($24{\pm}2yrs,\;177{\pm}5cm,\;72{\pm}8kg,\;10.5{\pm}2.3%$ body fat) underwent three experiments. In each experiment, subjects ran on a treadmill to reduce individual body mass to $2.2{\pm}0.1%$ and consumed one of three beverages containing 0, 4, or 8% alcohol over 60 min followed by 4 hr of resting recovery. They consumed approximately 150% of weight loss $(2053{\pm}204,\;2091{\pm}149,\;and\;1943{\pm}295mL)$ and content of alcohol was $9.9{\pm}1.0(0%),\;71.9{\pm}5.1(4%)$, and $132.2{\pm}20.1g$ (8% trial). Body weight, urine volume and samples, blood samples, and thirst sensation were measured five times; at baseline, immediately after exercise, and 0, 1st, and 4th hr of recovery. Blood alcohol concentration after ingestion was $0.0{\pm}0.0(0%),\;0.1{\pm}0.02(4%)$, and $0.2{\pm}0.03%$ (8% trial). No differences in blood sodium and potassium concentrations, and urine specific gravity were noticed over time periods and trials. Thirst sensation tended to be elevated in all trials immediately after exercises and urine output was elevated during the recovery. The magnitude of changes in these variables was proportional to the alcohol concentrations, but not statistically significant. While serum osmolality was not different among trials and time periods in 0 and 4% trials, it was higher during recovery than the baseline in the 8% trial (P<0.01). Triglycerides did not change throughout the time period and among trials. Free fatty acids were elevated after exercise in all trials and 4th hr of recovery in 0% (P<0.05). Subjects' net body fluid balance at 4th hr of recovery was negatively maintained and proportional to alcohol concentrations. Only 8% trials showed a significant reduction at 1st and 4th hr of recovery compared to 0 hr. The results suggested that diuretic effect of alcohol after moderate level of dehydration appeared dose dependent, but beverage containing alcohol up to 4% did not induce impaired rehydration than alcohol free drinks. Alcohol effects on fat mobilization during recovery appeared to be minimal and the mechanism is unclear.

걷기의 생리학적 분석 - 체력 증진을 위한 운동 - (Physiological Analysis of Walking - Physical Exercise for the Promotion of National Health -)

  • 남기용;장신요;신동훈;성낙응;엄륭의
    • The Korean Journal of Physiology
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    • 제4권1호
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    • pp.1-11
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    • 1970
  • Studies on the analysis of walking were performed on 33 male subjects. A prescription of physical exercise (walking at a speed of greater than 6 km/hr for more than one hour daily) for the promotion of individual health is presented on the basis of walking analysis. Presumptions were made that adequate physical exercise does promote health and is beneficial for the healthy life and increases the life span. These presumptions were derived from the numerous experimental literatures. The literatures support indirectly the presumptions. The following results were obtained and prescription of physical exercise is presented. 1. Oxygen uptake in a walking on a treadmill at a speed of 4 km/hr was only 3 times of the resting oxygen uptake. This kind of moderate exercise did not stimulate the cardiopulmonary system adequately. Heart rate at a 4 km/hr walking was 101 beats/min in boys of less than 20 years old and 83 beats/min in adults. Oxygen uptake at a 6 km/hr walking exceeded 4 times of the resting oxygen uptake. It was interpreted that walking at 6 km/hr stimulated the cardiopulmonary system for the promotion of health. Heart rate at this speed was greater than 110 beats/min in boys and greater than 100 beats/min in adults. 2. Heart rates in a walking of 10 km/hr were 172 beats/min in boys, and 143 beats/min in adults, respectively. Maximal heart rates were 185 beats/min in boys, 180 in office clerks, and 168 beats/min in construction site laboreres. 3. The correlation between heart rate and oxygen uptake was high, namely, r>0.95. Subsequently heart rate could be used as a measure of degree of intensity of physical exercise instead of the cumbersome oxygen uptake measurement. 4. The prescription of physical exercise for the promotion of health is: Daily walking for more than one hour at a speed of greater than 6 km/hr. Bodily functions in this daily walking are in boys (body weight, 50 kg): heart rates of 110 beats/min; breathing frequency, 28/min; oxygen uptake, greater than 4 times of the resting uptake; pulmonary ventilation, 351/min; stride, 124 strides/min; cumulative number of strides for one hour, 7,440 strides, and energy expenditure of more than 300 kcal. In adults (body weight, 60 kg) the bodily functions are: heart rates of 100 beats/min, breathing frequency, 28/min; oxygen uptake, greater than 4 times of the resting uptake; Pulmonary ventilation, 301/min; stride, 127 strides/min; cumulative number of strides for one hour, 7,670 strides, and energy expenditure of more than 300 kcal.

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Combined Trial of Fish Oil and Exercise Training Prevents Impairment in Insulin Action on Glucose Transport of Skeletal Muscle Induced by High-Fat Diet in Rats

  • Lee, Ji-Hyun;Kim, Jong-Yeon;Kim, Yong-Woon;Park, So-Young;Youn, Woon-Ki;Jang, Eung-Chan;Park, Deok-Il;Kim, Suck-Jun;Kim, Eun-Jung;Lee, Suck-Kang
    • The Korean Journal of Physiology and Pharmacology
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    • 제4권2호
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    • pp.91-97
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    • 2000
  • The purpose of the present study was to determine the preventive effects of combined interventional trial of fish oil treatment and exercise training on insulin resistance of skeletal muscle in high-fat fed rats. Male Wistar rats were randomly divided into chow diet (CD), high-fat diet (HF), high-fat diet with fish oil (FO), high-fat diet with exercise training (EX), and FO+EX groups. The rats in control group were fed chow diet containing, as percents of calories, 58.9% carbohydrate, 12.4% fat, and 28.7% protein. High-fat diet provided 32% energy as lard, 18% as corn oil, 27% as carbohydrate and 23% as casein. The fish oil diet had the same composition as the high fat diet except that 100 g menhaden oil was substituted for corn oil. Insulin sensitivity was assessed by in vitro glucose transport in the soleus muscle after diet treatment and treadmill running for 4 weeks. While the FO or EX only partially prevented insulin resistance on glucose transport and visceral obesity induced by high-fat diet, these interventions completely corrected hyperinsulinemia and hyperglycemia from the high-fat diet. The rats in the FO+EX showed normalized insulin action on glucose transport, plasma chemicals and visceral fat mass. Insulin-mediated glucose transport was negatively associated with total visceral fat mass (r=-0.734; p<0.000), plasma triglyceride (r=-0.403; p<0.05) and lepin (r=-0.583; p<0.001) concentrations with significance. Multiple stepwise regression analysis showed that only total visceral fat mass was independently associated with insulin-mediated glucose transport (r=-0.668; p<0.000). In conclusion, combined interventional trial of FO+EX recovered insulin resistance on glucose transport of skeletal muscle induced by high-fat diet. Visceral fat mass might be more important factor than plasma TG and leptin to induce insulin resistance on glucose transport of skeletal muscle in high-fat fed rats.

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Streptozotocin유도 당뇨쥐의 단기간 capsaicin 섭취와 운동이 혈중 지질, 항산화 효소 및 Akt량에 미치는 영향 (The Effects of Short-term Exercise and Capsaicin Supplementation on Serum Lipids, Antioxidants and Akt Contents in STZ-induced Diabetic Rats)

  • 서대윤;고정림;백영호
    • 생명과학회지
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    • 제18권12호
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    • pp.1739-1744
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    • 2008
  • 본 연구는 50 mg/kg의 STZ로 유발된 당뇨쥐에서 단기간 운동과 capsaicin 섭취가 혈중지질, 항산화 효소 및 Akt량에 미치는 영향을 알아보고자 31마리의 흰쥐를 대상으로 실험 하였다. 운동 군과 운동과 capsaicin을 병행한 군에서는 당뇨 유발 일주일 후 부터 15 m/min, 0%의 경사도로 25분간 주5회 2주간 트레드밀 운동을 실시하여 다음과 같은 결과를 얻었다. 혈중 지질 농도는 capsaicin 섭취와 운동을 병행한 군에서 TG는 유의하게 감소하였고, HDL-C는 다른 군에 비해 유의하게 높게 나타났고, ROS는 당뇨군을 제외한 모든 군에서 유의하게 감소하였다. CAT는 capsaicin만 섭취한 군에서 유의하게 증가하였고, SOD은 운동만 처치한 군과 capsaicin만 섭취한 군에서 유의하게 높았으며, GSH는 당뇨군을 제외한 모든 군에서 유의하게 높은 것으로 각각 나타났다. Akt효소는 capsaicin만 섭취한 군, p-Akt는 운동군에서 유의하게 증가하였다.

고강도 운동 시 성별에 따른 혈장 MDA, SOD 및 임파구 DNA 손상 변화 (Gender-Specific Changes of Plasma MDA, SOD, and Lymphocyte DNA Damage during High Intensity Exercise)

  • 조수연;정영수;곽이섭;노희태
    • 생명과학회지
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    • 제21권6호
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    • pp.838-844
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    • 2011
  • 본 연구는 고강도 1회성 운동 시 혈장 MDA와 SOD의 농도변화와 임파구 DNA 손상에 대한 성별의 차이를 평가하는데 목적이 있었다. 본 연구의 목적을 달성하기 위하여 남자 대학생과 여자 대학생을 대상으로 85%$VO_{2max}$ all-out 운동수행에 따른 혈장 MDA와 SOD 그리고 임파구 DNA 손상에 대한 분석을 실시하였으며, 연구 결과에 대한 결론은 다음과 같다. 85%$VO_{2max}$ all-out 운동에 따른 혈장 MDA와 SOD는 운동 종료 시 유의하게 증가하였으며, 통계적으로 유의한 차이는 나타나지 않았으나 남성이 여성에 비해 MDA는 높고 SOD는 낮은 경향을 보였다. 반면 85%$VO_{2max}$ all-out 운동에 따른 임파구 DNA 손상을 알아보기 위해 실시한 comet assay 결과 세 가지 parameter (%DNA in the tail, tail length, tail moment) 모두 운동 종료 시 유의하게 증가하였으며 남성의 %DNA in the tail과 tail length가 여성에 비해 통계적으로 유의하게 높게 나타났다. 따라서 본 연구 결과를 종합해보면 1회성 고강도 운동은 산화적 스트레스를 유발할 수 있으며 남성이 여성에 비해 산화적 손상이 더 크다고 보여진다. 그러나, DNA 손상에는 산화적 스트레스 외에도 체력, 호르몬 수치, 생활습관, 운동 강도 및 지속시간 등 여러 가지 요인들이 영향을 줄 수 있다고 보고되고 있어, 성별에 따른 DNA 손상에 대한 명확한 기전을 제시하기 위해서는 DNA 손상에 영향을 줄 수 있는 여러 요인들과의 관계를 고려한 지속적인 연구들이 필요하다고 생각된다.

Analyses of Plantar Foot Pressure and Static Balance According to the Type of Insole in the Elderly

  • Bae, Kang-Ho;Shin, Jin-Hyung;Lee, Joong-Sook;Yang, Jeong-Ok;Lee, Bom-Jin;Park, Seung-Bum
    • 한국운동역학회지
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    • 제26권1호
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    • pp.115-126
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    • 2016
  • Objective: The purpose of this study was to investigate plantar foot pressure and static balance according to the type of insole in the elderly. Methods: Thirteen elderly (mean age: $67.08{\pm}2.25years$, mean height: $159.63{\pm}9.64cm$, mean body weight: $61.48{\pm}9.06kg$) who had no previous injury experience in the lower limbs and a normal gait pattern participated in this study. Three models of insoles of the normal, 3D, and triangle types were selected for the test. The Pedar-X system and Pedar-X insoles, 3.3 km/h of walking speed, and a compilation of 20 steps walking stages were used to analyze foot-pressure distribution. Static balance test was conducted using Gaitview AFA-50, and balance (opening eyes, closing eyes) was inspected for 20 s. One-way ANOVA was conducted to test the significance of the results with the three insoles. p-value of less than .05 was considered statistically significant. Results: The mean foot pressure under the forefoot regions was the lowest with the 3D insole during treadmill walking (p<.05). The mean value under the midfoot was the highest with the 3D insole (left: p<.05, right: p<.01). The mean value under the rearfoot was the lowest with the 3D insole (p<.001). The maximum foot pressure value under the foot regions was the lowest on both sides of the forefoot with the 3D insole. A statistically significant difference was seen only in the left foot (p<.01). The maximum value under the midfoot was the highest with the 3D insole (p<.001). No statistically significant difference was detected on the values under the rearfoot. In the case of vertical ground reaction force (GRF), statistically significant difference was seen only in the left side rearfoot (p<.01). However, static balance values (ENV, REC, RMS, Total Length, Sway velocity, and Length/ENV) did not show significant differences by the type of insole. Conclusion: These results show that functional insoles can decrease plantar pressure and GRF under the forefoot and rearfoot. Moreover, functional insoles can dislodge the overload of the rearfoot and forefoot to the midfoot. However, functional insoles do not affect the static balance in the elderly.