• Asian-Australasian Journal of Animal Sciences
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• v.27 no.9
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• pp.1219-1227
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• 2014

A whole genome association (WGA) study was carried out to find quantitative trait loci (QTL) for sensory evaluation traits in Hanwoo. Carcass samples of 250 Hanwoo steers were collected from National Agricultural Cooperative Livestock Research Institute, Ansung, Gyeonggi province, Korea, between 2011 and 2012 and genotyped with the Affymetrix Bovine Axiom Array 640K single nucleotide polymorphism (SNP) chip. Among the SNPs in the chip, a total of 322,160 SNPs were chosen after quality control tests. After adjusting for the effects of age, slaughter-year-season, and polygenic effects using genome relationship matrix, the corrected phenotypes for the sensory evaluation measurements were regressed on each SNP using a simple linear regression additive based model. A total of 1,631 SNPs were detected for color, aroma, tenderness, juiciness and palatability at 0.1% comparison-wise level. Among the significant SNPs, the best set of 52 SNP markers were chosen using a forward regression procedure at 0.05 level, among which the sets of 8, 14, 11, 10, and 9 SNPs were determined for the respectively sensory evaluation traits. The sets of significant SNPs explained 18% to 31% of phenotypic variance. Three SNPs were pleiotropic, i.e. AX-26703353 and AX-26742891 that were located at 101 and 110 Mb of BTA6, respectively, influencing tenderness, juiciness and palatability, while AX-18624743 at 3 Mb of BTA10 affected tenderness and palatability. Our results suggest that some QTL for sensory measures are segregating in a Hanwoo steer population. Additional WGA studies on fatty acid and nutritional components as well as the sensory panels are in process to characterize genetic architecture of meat quality and palatability in Hanwoo.

• Journal of Microbiology and Biotechnology
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• v.30 no.10
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• pp.1567-1573
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• 2020

Ultraviolet (UV) is one of the major factors harmful to skin health. Irradiation with ultraviolet accelerates the decline of skin function, causing the skin to have deep wrinkles, dryness, decreased procollagen production, and degradation of collagen. Novel materials are needed to prevent the aging of the skin by blocking the effects of UV. Safflower seed oil (Charthamus tinctorius L., SSO) contains significantly high levels of unsaturated fatty acids and phytochemicals. SSO has been traditionally used in China, Japan, and Korea to improve skin and hair. Our objective in this study was to determine the effect of SSO and its active compound acacetin on UVB-induced skin photoaging in HaCaT cells and human dermal fibroblasts (HDF). SSO inhibited UVB-induced matrix metalloproteinase-1 (MMP-1) at both protein and mRNA levels in HaCaT cells and HDF. MMP-1 is known to play important roles in collagen degradation and wrinkle formation. Acacetin, a type of flavonoid, is present in SSO. Similar to SSO, acacetin also inhibited UVB-induced MMP-1 protein and mRNA levels in HaCaT cells and HDF. MMP-1 mRNA is primarily regulated by the mitogen-activated kinase (MAPK) signaling pathway. Acacetin regulated the phosphorylation of JNK1/2 and c-jun, but did not inhibit the phosphorylation of ERK1/2, p38 and AKT. Taken together, these results indicate that SSO and its active compound acacetin can prevent UVB-induced MMP-1 expression, which leads to skin photoaging, and may therefore have therapeutic potential as an anti-wrinkle agent to improve skin health.

• Journal of the Korea Safety Management & Science
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• v.17 no.1
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• pp.93-101
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• 2015

The demand from customers on better products and systems seems to be ever increasing. To meet the demand, the systems are becoming more and more complicated in terms of both scale and functionality, thereby requiring enormous effort in the development. One bright spot of this trend is that such effort has been the driving forces of the remarkable advancement in modern systems development. On the other hand, safety issues appear to be critical in many large-scale systems such as transportation and weapon systems including high-speed trains, airplanes, ships, missiles/rockets launchers, and so on. Such systems turn out to be prone to a variety of faults and thus the resultant failure can cause disastrous accidents. For the reason, they can be referred to as safety-critical systems. The systems failure can be attributed to either random or systemic factors (or sometimes both). The objective of this paper is on how to reduce potential systemic failure in safety critical systems. To do so, a proper system design is pursued to minimize the risk of systemic failure. A focus is placed on the fact that complex systems have a lot of complicated interfaces among the system elements. To effectively handle the sources of hazards at the complicated interfaces and resultant failure, a method is developed by utilizing a design structure matrix. As a case study, the developed method is applied in the design of train control systems.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.16 no.5
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• pp.38-48
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• 2017

Link attributes, such as speed, occupancy, and flow, are essential factors for transportation planning and operation. It is, therefore, one of the most important decision-making problems in intelligent transport system (ITS) to determine the optimal location of a sensor for collecting the information on link attributes. This paper aims to develop a model to determine the optimal location of a sensor to minimize the variability of traffic information on whole networks. To achieve this, a network sensor location model (NSLM) is developed to reflect discrete characteristics of data collection. The variability indices of traffic information are calculated based on the summation of diagonal elements of the variance-covariance matrix. To assess the applicability of the developed model, speed data collected from the dedicated short range communication (DSRC) systems were used in Daegu metropolitan area. The developed model in this study contributes to the enhancement of investment efficiency and the improvement of information accuracy in intelligent transport system (ITS).

• Transactions of the Korean Society of Mechanical Engineers A
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• v.27 no.10
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• pp.1644-1652
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• 2003

The monitor product is packed by cushioning materials because the monitor can be broken during transportation. However, the addition of the cushioning material increased the volume of the product. Therefore, it is required that the usage of cushioning material be minimized. In practice, design engineers have followed the ad hoc design with experiences of predecessors. Automation of the design process is very important for the reduction of engineering cost, and can be achieved by an excellent design process and software development. According to Axiomatic design, a design flow is defined and a software system is developed for automated design. At first, a basic model is defined. A user can modify the model from menus and design is carried out according to the input from the user. Finite element models are automatically generated based on the design. A nonlinear finite element analysis program called LS/DYNA3D is linked for the impact analysis. The process of Design of Experiments using orthogonal array is installed to minimize the maximum acceleration in drop test. Therefore, a new design can be proposed by the system. The program is designed according to the Independence Axiom of Axiomatic design. FRs and DPs of the software system are defined and decomposed by zigzagging process. Independent modules can be generated by analysis of the full design matrix and each module is coded as class in Object Oriented Programming (OOP). Design results are discussed.

• Journal of Korea Water Resources Association
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• v.47 no.12
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• pp.1213-1225
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• 2014

The development of bars and sediment sorting processes in the braided channels with the mixed grain sizes are investigated experimentally in this study. The sediment in the steep slope channels discharges with highly fluctuation. However, it discharges with relatively periodic cycles in the mild slope channels. The characteristics and amplitudes of the dominant bars are examined by double fourier analysis. The dimensionless sediment particle size decreases as the longitudinal bed elevation increases. However, the size increases as the longitudinal bed elevation decreases. As the dimensionless critical tractive force in the surface layer ratio to the force in the subsurface layer increases, the surface geometric mean size of sediments and the dimensionless sediment particle size decrease. This means that coarse matrix is formed with the dimensionless tractive force by the sediment selective sorting.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.10
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• pp.936-942
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• 2015

This paper suggests the significant strategies and their priority to deal with space transportation market trends. First, market trends related with technical improvement and change in demand are analyzed by the literature research. The three key trends are obtained: 'Increasing Demand of High-Performance Launch Vehicles', 'Rising of Low-Price Launch Vehicles', and 'Rising of Dual/Multi-Launch'. And then, strategies for developing the launch vehicle industry in Korea are selected from several studies about commercialization of Korean launch vehicle. The strategies are evaluated by the experts through pairwise comparison matrix and the criteria for this process is how significantly does the strategy effect on the launch vehicle industry through market assessment. As a result, reliable order of priority among the strategies are obtained. Under the three key trends, strategy to enhance reliability is most important. And, strategy to have price competitiveness has secondary priority to deal with 'Rising of Low-Price Launch Vehicles' trend and 'Rising of Dual/Multi-Launch' trend. On the contrary, strategy of government's support is secondary under 'Increasing Demand of High-Performance Launch Vehicles' trend.

• Proceedings of the Materials Research Society of Korea Conference
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• 2009.05a
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• pp.13.1-13.1
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• 2009

Transparent electronics has attracted many interests, for it can open new applications for consumer electronics, transportation, business, and military. Among them, display backplane, thin film transistor (TFT) array would be the most attractive application. Many researchers have been investigating oxide semiconductors for transparent channel material of TFT since the report for transparent amorphous oxide semiconductor (TAOS) TFT by Hosono group and ZnO TFT by Wager group. Especially, oxide TFTs have been intensively investigated during a couple of years since the first demonstration of ZnO-TFT driving AM-OLED. Many papers regarding the fabrication and performance of oxide TFTs, and active matrix display driven by oxide TFTs have been reported. Now lots of people have confidence in the competitiveness of oxide TFTs for the backplane of AM-Display. Especially, high mobility, uniformity, fairly good stability, and low cost process make oxide TFTs applied even to a large size AM-OLED. Last year, Samsung mobile display, former SID, reported 12" AM-OLED driven by IZGO-TFT and it seems that the remained issue for the mass production is the bias temperature stability. Here, we will introduce the application of oxide TFT and important issue for oxide TFT to be used for the direct printing.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.22 no.4
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• pp.634-640
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• 2018

In this paper, we propose an automatic extraction algorithm of region of interest(ROI) based on medical x-ray images. The proposed algorithm uses segmentation, feature extraction, and reference image matching to detect lesion sites in the input image. The extracted region is searched for matching lesion images in the reference DB, and the matched results are automatically extracted using the Kalman filter based fitness feedback. The proposed algorithm is extracts the contour of the left hand image for extract growth plate based on the left x-ray input image. It creates a candidate region using multi scale Hessian-matrix based sessionization. As a result, the proposed algorithm was able to split rapidly in 0.02 seconds during the ROI segmentation phase, also when extracting ROI based on segmented image 0.53, the reinforcement phase was able to perform very accurate image segmentation in 0.49 seconds.

• Journal of Navigation and Port Research
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• v.27 no.4
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• pp.465-469
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• 2003

It has well known that MUSIC and ESPRIT algorithms estimate angle of arrival(AOA) with high resolution by eigenvalue decomposition of the covariance matrix which were obtained from the array antennas, However, the disadvantage of MUSIC and ESPRIT is that they are computationally ineffective, and then they are difficult to implement in real time. the other problem of MUSIC and ESPRIT is to require calibrated antennas with uniform features, and are sensitive ti the manufacturing fault and other physical uncertainties. To overcome these disadvantages, several method using neural model have been study. For multiple signals, those methods require huge training data prior to AOA estimation. This paper proposes the algorithm for AOA estimation by interconnected Hopfield neural model. Computer simulations show the validity of the proposed algorithm. It follows that the proposed method yields better AOA estimates than MUSIC. Moreover, out method does not require huge training procedure and only assigns interconnected coefficients to the neural network prior to AOA estimation.