• Archives of Pharmacal Research
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• v.20 no.5
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• pp.420-424
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• 1997

By human intestinal bacteria, saikosaponin c was transformed to four metabolites, prosaikogenin E1 (E1) prosaikogenin E2 (E2), prosaikogenin E3 (E3) and saikogenin E. Metabolic time course of saikosaponin c was as follows; in early time, saikosaponin c was converted to E1 and E2, and then these were transformed to saikogenin E via E3. Also, this metabolic pathway was similar to the metabolism of saikosaponin c by rat intestinal bacteria. Bacteroides JY-6 and Bacteroides YK-4, the bacteria isolated from human intestinal bacteria, could transform saikosaponin c to E via E1 (or E2) and E3. However, these bacteria were not able to directly transform El and E2 to saikogenin E. Naringin was mainly transformed to naringenin by human intestinal bacteria. The minor metabolic pathway transformed naringin to naringenin via prunin. By JY-6 or YK-4, naringin was metabolized to naringenin only via prunin.

• Transactions of the Korean Society of Mechanical Engineers
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• v.18 no.5
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• pp.1158-1168
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• 1994

For BEM analyses of the impact problems of dissimilar materials, the connected multi-region method using perfect bonded conditions on the interface boundaries was added to two-dimensional Laplace transformed-domain BEM program for a single region analysis. It was confirmed that the BEM results of impact problems of a single-region and multi-regions for a homogeneous isotropic material are agreed well. The two-dimensional Laplace transformed-domain BEM program combined with connected multi-region method was applied to analyse several impact problems of dissimilar materials. Also the feasibility of BEM impact analyses was investigated for dissimilar materials by the analysis of the BEM results for impact problems of dissimilar materials in terms of physical aspects. As for an application, the two-dimensional Laplace transformed BEM concerning impact problems of cracks at the interface of dissimilar materials and the determinating process of the dynamic stress intensity factors by extrapolation method are presented in this paper.

• The Transactions of the Korea Information Processing Society
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• v.5 no.10
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• pp.2546-2555
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• 1998

Existing Systems need to be modified due to the change of environment, the emergence of new technology and the requirement of change. One of the features of system transformation is how functions of the old system is preserved in the transformed system after reverse-engineering. But, the techniques to evaluate and verigy the transformed system have proceeded more partially and fragmentarily. In this paper, we have proposed the functional coverage and developed the tool and techniques for verifying functional euivalence between a procedural software and a transformed object-oriented software. The tool and methods are efficiently used to verigy whehter the transformed program preserves the same functionality as the existing program.

• Archives of Pharmacal Research
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• v.27 no.8
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• pp.845-849
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• 2004

Many studies have focused on the anticarcinogenic, antimutagenic or chemopreventive activi-ties of capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide) which is a major pungent ingredient in red pepper. We have previously shown that capsaicin selectively induces apoptosis in H-ras-transformed MCF10A human breast epithelial cells but not in their normal cell counter-parts (Int. J. Cancer, 103, 475-482,2003). In this study, we investigated the possible roles of reactive oxygen species (ROS) and Rac1 in capsaicin-induced apoptosis of H-ras MCF10A cells. Selective induction of ROS generation by capsaicin treatment was observed only in H-ras MCF10A cells. Pretreatment of H-ras MCF10A cells with an antioxidant N-acetylcysteine(NAC) significantly reversed capsaicin-induced growth inhibition, suggesting that ROS may mediate the apoptosis of H-ras-transformed cells induced by capsaicin. Rac1 was prominently activated by H-ras in MCF10A cells. Based on the studies using a wild type Rac1 and a domi-nant negative Rac1 constructs, we propose that Rac1 activity is critical for inhibitory effect of capsaicin on growth of H-ras-transformed MCF10A cells possibly through ROS generation.

• The Korean Journal of Applied Statistics
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• v.19 no.1
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• pp.111-120
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• 2006

In a two-stage two-level balanced nested design, type I error rates for the parametric tests and the rank transformed tests for the main effects and the nested effects are in overall similar to each other. Furthermore, powers for the rank transformed statistic for the main effects and the nested effects in a two-stage two-level balanced nested design are generally superior to powers for the parametric statistic When the effect size and the sample size are increased, we can find that powers increase for the parametric statistic and the rank transformed statistic are dramatically improved. Especially for the case of the fixed effects in the asymmetric distributions such as an exponential distribution, powers for the rank transformed tests are quite high rather than powers for the parametric tests.

• Journal of architectural history
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• v.10 no.4 s.28
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• pp.23-41
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• 2001

This paper aims at understanding the transformed characteristics of expressional system of Church architecture in Korean traditional style. Through the analysis of transformed forms and its meanings of those, this paper investigates the unique process of stylistic development of Korean traditional church architecture in early modern, 1900's. The method of this study is the analyse of them after the actual field surveys of Korean traditional churches, specially eclecticism churches as the HWSAN church and KUPODONG church, and the analysis of Semiology. Theory for Semantic Interpretation of artistic objects as an objects of art and architecture. Specially, the survey concentrates on the architectural elements(the form, the architectural structure, the material, the roof shape, the window, the door, the bell tower, the plan, etc) of eclecticism churches, especially those of HWASAN church and the analysis of semiology theory contains the research results which were studied by theorists as Charles Jencks, Umberto Eco and Juan Pablo Bonta. Acceding to analysis, Korean eclecticism churches have the unique transformation process and specific meaning of the spontaneous process of development. In the results of the semiological analysis of HWASAN church, it can be revealed clearly that transformed process of form리 characteristics of HWASAN church intented to formal originality of western Gothic church, but its form and meaning were based not on any simply imported western style but on existing system of Korean architecture.

• Korean Institute of Interior Design Journal
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• no.41
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• pp.206-214
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• 2003

The purpose of this study was to investigate the antique chair style in Korean market. The examined objects were 235 chairs in selected 30 antique shops dealing with curios in Seoul from July 16 to August 23 in 2002. The results of this study was as follows Antique chairs in Korean market are revival style and eclectic style. The revival style are copied or transformed period style antique chairs. The eclectic style are chairs newly designed by mixing of 2 or 3 different types period style antique-chairs. Rococo-revival style were the most prevalent following Renaissance style chairs in the market. In case of chair back and legs the Classic revival style are made by copying and transforming the Klismos, Hepplewhite, Sheraton, which is a neo-classic style. The Gothic revival style are copied or transformed finial, foil, crocket and tracery which is the Gothic architectural decoration. In Renaissance revival style. Elizabeth, slat, caned, padded, yorkshire, bobbin turned, William & Mary are copied and transformed for the chair back. In Rococo-revival style, LouisXV, Queen Anne, Chippendale of Rococo-style- chair back and cabriole legs are copied or transformed. In the eclectic style, Classic style chair back with Renaissance-style legs or Rococo style chair back with Renaissance style legs are combined as a periodical eclectic style. In this manner now style of chair back and the periodical style of legs were used together as a new eclectic style chair.

• Investigative Magnetic Resonance Imaging
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• v.19 no.1
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• pp.19-30
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• 2015

Purpose: A new compressed sensing technique by iterative truncation of small transformed coefficients (ITSC) is proposed for fast cardiac CINE MRI. Materials and Methods: The proposed reconstruction is composed of two processes: truncation of the small transformed coefficients in the r-f domain, and restoration of the measured data in the k-t domain. The two processes are sequentially applied iteratively until the reconstructed images converge, with the assumption that the cardiac CINE images are inherently sparse in the r-f domain. A novel sampling strategy to reduce the normalized mean square error of the reconstructed images is proposed. Results: The technique shows the least normalized mean square error among the four methods under comparison (zero filling, view sharing, k-t FOCUSS, and ITSC). Application of ITSC for multi-slice cardiac CINE imaging was tested with the number of slices of 2 to 8 in a single breath-hold, to demonstrate the clinical usefulness of the technique. Conclusion: Reconstructed images with the compression factors of 3-4 appear very close to the images without compression. Furthermore the proposed algorithm is computationally efficient and is stable without using matrix inversion during the reconstruction.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• v.9 no.2
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• pp.473-476
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• 2005

This paper is proposed a robust various feature parameters in noise. Feature parameter MFCC(Mel Frequency Cepstral Coefficient) used in conventional speech recognition shows good performance. But, parameter transformed feature space that uses PCA(Principal Component Analysis)and ICA(Independent Component Analysis) that is algorithm transformed parameter MFCC's feature space that use in old for more robust performance in noise is compared with the conventional parameter MFCC's performance. The result shows more superior performance than parameter and MFCC that feature parameter transformed by the result ICA is transformed by PCA.

• The Journal of the Society of Stroke on Korean Medicine
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• v.17 no.1
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• pp.39-44
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• 2016

■ Objectives A case of a 44 years old Korean female with left side headache due to Transformed migraine is presented. ■ Methods He was treated with electroacupuncture around eyes and dry cupping on shoulder, moxibustion, acupuncture and herbal medicine, Chai Ling Tang. Then we evaluated the improvement by Pain area comparison and Numerical Rating Scale(NRS). ■ Results Headache was improved after the administration of Korean medical treatments. ■ Conclusion Korean medical treatment may be effective in treating headache due to Transformed migraine.