• Title/Summary/Keyword: transformation groups

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Limited Impact of Music Therapy on Patient Anxiety with the Large Loop Excision of Transformation Zone Procedure - a Randomized Controlled Trial

  • Kongsawatvorakul, Chompunoot;Charakorn, Chuenkamon;Paiwattananupant, Krissada;Lekskul, Navamol;Rattanasiri, Sasivimol;Lertkhachonsuk, Arb-Aroon
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.6
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    • pp.2853-2856
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    • 2016
  • Background: Many studies have pointed to strategies to cope with patient anxiety in colposcopy. Evidence shows that patients experienced considerable distress with the large loop excision of transformation zone (LLETZ) procedure and suitable interventions should be introduced to reduce anxiety. This study aimed to investigate the effects of music therapy in patients undergoing LLETZ. Materials and Methods: A randomized controlled trial was conducted with patients undergoing LLETZ performed under local anesthesia in an out patient setting at Ramathibodi Hospital, Bangkok, Thailand, from February 2015 to January 2016. After informed consent and demographic data were obtained, we assessed the anxiety level using State Anxiety Inventory pre and post procedures. Music group patients listened to classical songs through headphones, while the control group received the standard care. Pain score was evaluated with a visual analog scale (VAS). Statistical analysis was conducted using Pearson Chi-square, Fisher's Exact test and T-Test and p-values less than 0.05 were considered statistically significant. Results: A total of 73 patients were enrolled and randomized, resulting in 36 women in the music group and 37 women in the non-music control group. The preoperative mean anxiety score was higher in the music group (46.8 VS 45.8 points). The postoperative mean anxiety scores in the music and the non-music groups were 38.7 and 41.3 points, respectively. VAS was lower in music group (2.55 VS 3.33). The percent change of anxiety was greater in the music group, although there was no significant difference between two groups. Conclusions: Music therapy did not significantly reduce anxiety in patients undergoing the LLETZ procedure. However, different interventions should be developed to ease the patients' apprehension during this procedure.

Precise Synthesis of Dendron-Like Hyperbranched Polymers and Block Copolymers by an Iterative Approach Involving Living Anionic Polymerization, Coupling Reaction, and Transformation Reaction

  • Hirao Akira;Tsunoda Yuji;Matsuo Akira;Sugiyama Kenji;Watanabe Takumi
    • Macromolecular Research
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    • v.14 no.3
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    • pp.272-286
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    • 2006
  • Dendritic hyperbranched poly(methyl methacrylate)s (PMMA)s, whose branched architectures resemble the 'dendron' part(s) of dendrimer, were synthesized by an iterative methodology consisting of two reactions in each iteration process: (a) a coupling reaction of u-functionalized, living, anionic PMMA having two tert-butyldimethylsilyloxymethylphenyl(SMP) groups with benzyl bromide(BnBr)-chain-end-functionalized PMMA, and (b) a transformation reaction of the introduced SMP groups into BnBr functionalities. These two reactions, (a) and (b), were repeated three times to afford a series of dendron-like, hyperbranched (PMMA)s up to third generation. Three dendron-like, hyperbranched (PMMA)s different in branched architecture were also synthesized by the same iterative methodology using a low molecular weight, functionalized 1,1-diphenylalkyl anion prepared from sec-BuLi and 1,1-bis(3-tert-butyldime-thylsilyloxymethylphenyl)ethylene in the reaction step (b) in each iterative process. Furthermore, structurally similar, dendron-like, hyperbranched block copolymers could be successfully synthesized by the iterative methodology using $\alpha$-functionalized, living, anionic poly(2-(perfluorobutyl) ethyl methacrylate) (PRfMA) in addition to $\alpha$-functionalized, living PMMA. Accordingly, the resulting block copolymers were comprised of both PMMA and PRfMA segments with different sequential orders. After the block copolymers were cast into films and annealed, their surface structures were characterized by angle-dependent XPS and contact angle measurements. All three samples showed significant segregation and enrichment of PRfMA segments at the surfaces.

Fast and Soft Functionalization of Carbon Nanotube with -SO3H, -COOH, -OH Groups for Catalytic Hydrolysis of Cellulose to Glucose

  • Lusha, Qin;Lee, Sungho;Li, Oi Lun
    • Journal of the Korean institute of surface engineering
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    • v.53 no.3
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    • pp.87-94
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    • 2020
  • Herein, sulfonated carbon nanotubes (CNT) have been prepared in dilute sulfuric acid (H2SO4) via a novel sulfonation approach based on gas-liquid interfacial plasma (GLIP) at room temperature. The sulfonic acid groups and total acid groups densities of CNT after GLIP treatment in 2 M H2SO4 for 45 min can reach to 0.53 mmol/g and 3.64 mmol/g, which is higher than that of sulfonated CNT prepared under 0.5 M / 1 M H2SO4. The plasma sulfonated CNT has been applied as catalysts for the conversion of microcrystalline cellulose to glucose. The effect of hydrolysis temperature and hydrolysis time on the conversion rate and product distribution have been discussed. It demonstrates that the total conversion rate of cellulose increasing with hydrolysis temperature and hydrolysis time. Furthermore, the GLIP sulfonated CNT prepared in 2 M H2SO4 for 45 min has shown high catalytic stability of 85.73 % after three cycle use.

Characteristics of Surface Modified Activated Carbons Prepared by Potassium Salt Sequentially After Hydrochloric Acid Treatment

  • Oh, Won-Chun;Park, Chong-Sung;Bae, Jang-Soon;Ko, Young-Shin
    • Carbon letters
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    • v.7 no.1
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    • pp.34-41
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    • 2006
  • The objective of this paper is to compare the variation of surface properties by hydrochloric acid pre-treatment and of metallic potassium and their salts loading effect for activated carbon after surfaces transformation by acid. From the results of nitrogen adsorption, each isotherm shows a distinct knee band, which is closely related to the characteristic of microporous carbons with capillary condensation in micropores. In order to present the causes of the differences in surface properties and $S_{BET}$ after the samples were treated with hydrochloric acid, pore structure and surface morphology are investigated by adsorption analysis. X-ray diffraction (XRD) patterns indicate that activated carbons show better performance for metallic potassium and potassium salts by pre-treatment with hydrochloric acid. Scanning electron microscopy (SEM) pictures of potassium/activated carbon particles provide information about the homogeneous distribution of metal or metal complex on the surface. For the chemical composition microanalysis for potassium treatment of the activated carbon pre-treated with hydrochloric acid, samples were analyzed by energy disperse X-ray (EDX). Finally, the type and quality of oxygen groups are determined from the method proposed by Boehm. A positive influence of the acidic groups on the carbon surface by acid treatment is also demonstrated by an increase in the contents of potassium salts with increasing of acidic groups calculated from Boehm titration.

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Virus Resistant and Susceptible Transgenic Nicotiana benthamiana Plants Expressing Coat Protein Gene of Zucchini green mottle mosaic virus for LMO Safety Assessment

  • Kim, Min-Jea;Choi, Sun-Hee;Kim, Tae-Sung;Park, Min-Hye;Lim, Hee-Rae;Oh, Kyung-Hee;Kim, Tae-San;Lee, Min-Hyo;Ryu, Ki-Hyun
    • The Plant Pathology Journal
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    • v.20 no.3
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    • pp.206-211
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    • 2004
  • Transgenic Nicotiana benthamiana plants harboring coat protein (CP) gene of Zucchini green mottle mosaic virus (ZGMMV) were generated for virus-resistant screening and complementation analysis of related viruses for environmental safety assessment (SA) of living modified organism (LMO) purposes. Transformation of leaf disc of N.benthamiana was performed by using Agrobacterium-mediated method and the pZGC-PPGA748 containing the ZGMMV CP and NPTII genes. Two kinds of transgenic homozygous groups, virus-resistant and virus-susceptible N.benthamiana lines, were obtained by screening of challenging homologous virus for Tl generations. These two pathologically different lines can be useful for host-virus interactions and LMO environmental SA.

Chemical Transformation of Individual Asian Dust Particles Estimated by the Novel Double Detector System of Micro-PIXE

  • Ma, Chang-Jin
    • Asian Journal of Atmospheric Environment
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    • v.4 no.2
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    • pp.106-114
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    • 2010
  • By the application of novel double detector system of micro-PIXE that can detect light elements (Z<14), we made an attempt to provide a thorough discussion on the aging processes of Asian dust (hereafter called "AD") particle by reaction with sea-slat. The elemental spectra and maps obtained from the microbeam radiation of micro-PIXE to individual AD particles were useful for fractionating AD particles into both internally and externally mixed particles. A spatial distribution of elements in a minute domain of single particle obtained by scanning the microbeam irradiation enabled us not only to estimate the chemical mixing state of individual AD particles but also to presume their aging processes in both ambient air and cloud. By calculating the normalized micro-PIXE net count of elements, it was possible to classify individual AD particles into three distinct groups (i.e., (1) Aging type 1: AD particle coated by the gaseous Cl evaporated by the reaction between artificial acids and sea salt; (2) Aging type 2: AD particle mixed with sea salt but no additional reaction with artificial acids; and (3) Non-aged type) A relatively high transformation rate (63.3-75.9%) was shown in large particles (greater than $5.1\;{\mu}m$ in diameter).

Enzymatic transformation of ginsenosides in Korean Red Ginseng (Panax ginseng Meyer) extract prepared by Spezyme and Optidex

  • Choi, Hyeon-Son;Kim, Sun Young;Park, Yooheon;Jung, Eun Young;Suh, Hyung Joo
    • Journal of Ginseng Research
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    • v.38 no.4
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    • pp.264-269
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    • 2014
  • Background: In this study, we examined the effects of various enzymes on chemical conversions of ginsenosides in ginseng extract prepared by amylases. Methods: Rapidase, Econase CE, Viscozyme, Ultraflo L, and Cytolase PCL5 were used for secondary enzymatic hydrolysis after amylase treatment of ginseng extract, and ginsenoside contents, skin permeability, and chemical compositions including total sugar, acidic polysaccharide, and polyphenols were determined on the hydrolyzed ginseng extract. Results: Rapidase treatment significantly elevated total ginsenoside contents compared with the control (p < 0.05). In particular, deglycosylated ginsenosides including Rg3, which are known as bioactive compounds, were significantly increased after Rapidase treatment (p < 0.05). The Rapidase-treated group also increased the skin permeability of polyphenols compared with the control, showing the highest level of total sugar content among the enzyme treatment groups. Conclusion: This result showed that Rapidase induced the conversion of ginsenoside glycosides to aglycones. Meanwhile, Cytolase PCL5 and Econase treatments led to a significant increase of uronic acid (acidic polysaccharide) level. Taken together, our data showed that the treatments of enzymes including Rapidase are useful for the conversion and increase of ginsenosides in ginseng extracts or products.

Governance of A Public Platform Project in the Context of Digital Transformation Focusing on the 'Special Delivery' (공공플랫폼 구축사업의 거버넌스: 경기도 배달플랫폼 '배달특급'의 사례를 중심으로)

  • Seo, Jeongone
    • Journal of Information Technology Services
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    • v.21 no.5
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    • pp.15-28
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    • 2022
  • Recently, government agencies are actively adopting the platform model as a means of public policy. However, existing studies on the public platform are minimal and have focused on user experiences or the possibility of public usage of the platform model. Now the research concerning building governance structure and utilizing network effects of the platform after adopting the platform model in the public sector is keenly required. This study intended to ignite academic dialogue on the governance of public platforms in the context of digital transformation. This study focused on a case of the 'Special delivery,' a public delivery app established by Gyeonggi-do. In order to analyze the characteristics of the public platform and its governance structure, data were collected from press releases, policy reports, and news articles. Data was analyzed using the frame of Hagui's platform design factors and Ansell & Gash's collaborative governance model. The results of the public platform analyses showed 1) incompleteness in the value trade-off accounting, which was designed for platform business based on general cost-benefit analysis, and 2) a closed governance structure that limits direct participation of diverse user groups(i.e., service provider, customer) in order to enhance providers' utility by preventing customers' excessive online activities. The results of this study provided theoretical and policy implications regarding designing the strategy for accounting for value trade-offs and functioning governance structure for public platforms.

Multi-Sided Networks of Digital Platform Ecosystem: The Case of Ride-Hailing in Indonesia

  • Mohammad Nabil Almunawar;Muhammad Anshari
    • Asia pacific journal of information systems
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    • v.30 no.4
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    • pp.808-831
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    • 2020
  • The business world has been undergoing a digital transformation. The adoption of multi-sided digital platform across the world has sped up this transformation. Multi-sided digital platforms create value by mediating interactions and transactions of distinct groups of users. A platform and its stakeholders need to be considered as a business ecosystem. Elements or components in the ecosystem exchange values and together form a network of exchange values. The objective of this paper is to construct a framework for crafting and observing digital business ecosystems. The foundation theories used to construct the framework are transaction cost economy (TCE), multi-sided markets, and value network. This paper uses Go-Jek, a growing ride-hailing platform from Indonesia, as a case to discuss how the framework works in mapping Go-Jek's digital business ecosystem, and then explain its expansion strategy. This paper has both theoretical and managerial contributions. It provides a formal definition of digital business ecosystems as a network of exchange values. The framework does not only help studies the existing business ecosystems but also can be used to craft a new business ecosystem. It can also be used to study value exchanges within the ecosystem, assessing or crafting ecosystem expansion strategies.

Rapid Speaker Adaptation Based on MAPLR with Adaptive Hybrid Priors Estimated from Reference Speakers (참조화자로부터 추정된 적응적 혼성 사전분포를 이용한 MAPLR 고속 화자적응)

  • Song, Young-Rok;Kim, Hyung-Soon
    • The Journal of the Acoustical Society of Korea
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    • v.30 no.6
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    • pp.315-323
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    • 2011
  • This paper proposes two methods of estimating prior distribution to improve the performance of rapid speaker adaptation based on maximum a posteriori linear regression (MAPLR). In general, prior distribution of the transformation matrix used in MAPLR adaptation is estimated from all of the training speakers who are employed to construct the speaker-independent model, and it is applied identically to all new speakers. In this paper, we propose a method in which prior distribution is estimated from a group of reference speakers, selected using adaptation data, so that the acoustic characteristics of the selected reference speakers may be similar to that of the new speaker. Additionally, in MAPLR adaptation with block-diagonal transformation matrix, we propose a method in which the mean matrix and covariance matrix of prior distribution are estimated from two groups of transformation matrices obtained from the same training speakers, respectively. To evaluate the performance of the proposed methods, we examine word accuracy according to the number of adaptation words in the isolated word recognition task. Experimental results show that, for very limited adaptation data, statistically significant performance improvement is obtained in comparison with the conventional MAPLR adaptation.