• Natural Product Sciences
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• 제21권3호
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• pp.185-191
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• 2015

Comparative molecular analysis has been frequently adopted for the authentication of herbal medicines as well as the identification of botanical origins. Roots and rhizomes of the family Umbelliferae have been used as traditional herbal medicines to relieve various symptoms such as inflammation, neuralgia and paralysis in countries of East Asia. Since most herbal medicines of the Umbelliferae roots or rhizomes are generally supplied in the form of dried slices, morphological examination does not often provide sufficient evidence to identify the botanical origin. Using species-specific probes developed by the comparative analysis of nrDNA ITS sequences, a DNA chip was developed to identify herbal medicines for 13 species in the Umbelliferae. The developed DNA Chip proves its potential as a rapid, sensitive and effective tool for authenticating herbal medicines in future.

• Advances in Traditional Medicine
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• 제4권3호
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• pp.125-136
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• 2004

The pharmacological mechanisms of most Oriental medicines have not been clearly defined in spite of their effective use in treating many diseases throughout the world. Many Oriental medicines have been used against various allergic diseases for generations, and still occupy an important place in traditional medicine in far eastern countries including Korea. It is also still unclear how Oriental drugs prevent allergic disease in vivo or in vitro models. Some Korean folk medicine inhibited the mast cell-mediated allergic reaction. This review summarizes the effective folk medicine in experimental effect on systemic or local anaphylaxis reaction. Potential anti-anaphylactic folk medicines include: Poncirus trifoliata; Siegesbeckia glabrescence; Solanum lyratum; Aquilaria agallocha; Ulmi radicis; Polygonum tinctorium; Hwanglyun-Haedok-Tang; Rehmannia glutinosa; Kum-Hwag-San; Syzygium aromaticm; Spirulina platensis; Sosiho-Tang; Sinomenium acutum; Schizonepta tenuifolia; Shini-San; Magnoliae flos; Sochungryong-Tang; Oryza sativa; Cryptotympana atrata; Salviae radix; Rosa davurica; Asiasari radix; Chung-Dae-San; Cichorium intybus; Perilla frutescens; Vitex rotundifolia; Terminalia chebula; Siberian Ginseng; Solanum melongena; Gahmi-Shini-San; Alpinia oxyphylla; Acanthopanax senticosus root; Prunella vulgaris; Allergina; Ixeris dentate; Acanthopanax senticosus stem; Tongkyutang; Salvia plebeia; Rubus coreanus; Sinpo- Tang; Dodutang; Forsythia fructus; Xanthii fructus; and Purple bamboo slat. Ensuring the effects and understanding the mechanisms of action for these Oriental medicines can permit drug development and laying of the ground-work for evaluating potential synergistic effects by addition and subtraction of prescriptions.

• Preventive Nutrition and Food Science
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• 제10권2호
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• pp.198-205
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• 2005

Korean medicated diet (KMD) is not a simple combination of food and Chinese drugs, but a special carefully constructed diet made from Sasang constitutional medicines, food and condiments under the theoretical guidance of diet preparation based on differentiation of symptoms and signs of traditional Sasang medicine (TSM). It combines the functional efficacy of medicine with the delicacy of food, and can be used to prevent and cure diseases, build up one's health and prolong one's life. Korean traditional medicated diet has a long history of development. Although influenced by Chinese medicine, Korean traditional medicine has been developed into a unique system of traditional medicine that has surpassed the continental medical practice, sublimating itself into a native medical practice suitable to Korean lifestyles and physical constitutions. In the 19th century, Lee Jema's Sasang medicine (medicine of four types of energy determining the physical constitution) was introduced. It is an integration of mind and body according to the individual's physical constitution that is categorized allowing a customized method of treatment ideal for each category-making the content of Korean traditional medicated diet even richer. The characteristics of Korean medicated diet are as follows: (1) Laying stress on the wole, selecting medicated diet on the basis of differential diagnosis. (2) Suitable for prevention and treatment, outstanding in effect. (3) Good in taste, convenient for taking. KMD refers to drink and food according to certain prescriptions, by processing and cooking that can be used either for prevention and cure of diseases, or for health care and recovery. The purpose of this review is to introduce TSM and KMD based on Sasang constitutional medicines.

• 동의신경정신과학회지
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• 제35권1호
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• pp.69-99
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• 2024

Objectives: This study aimed to systematically review the effectiveness and safety of traditional herbal medicine treatments for metabolic syndrome (MS) in patients receiving antipsychotic drugs (APs). Methods: We searched 11 domestic and foreign databases for randomized controlled trials (RCTs) using traditional herbal medicines for MS in patients receiving APs. Results: Twenty RCTs conducted in China were included in the analysis. The most common disease among the participants was schizophrenia. Most studies used the 2004 Chinese Diabetes Society (CDS) standards as the diagnostic criteria for MS. The most used prescription was Yukultang (Liuyu-tang). The most used herbal material was Pinelliae Rhizoma, followed by Poria, Citri Reticulatae Pericarpium, and Glycyrrhizae Radix et Rhizoma. Traditional herbal medicines were mostly reported to improve the symptoms of MS. Conclusions: Traditional herbal medicines may be effective in improving the symptoms of MS in patients receiving APs. However, the quality of the included studies was low, and the studies were heterogeneous. Methodologically rigorous clinical studies on traditional herbal medicine treatments for MS in patients receiving APs are needed.

• 한국식품저장유통학회지
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• 제13권2호
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• pp.241-245
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• 2006

국산 한약계 추출물을 첨가하여 제조한 전통 콩된장의 아질산염 소거작용, 수소공여능, 항균활성 및 혈전용해능 등을 검토하였다. 한약재 추출물을 첨가하여 제조한 된장은 대조구 된장에 비하여 대부분이 높은 아질산염 소거능을 나타내었다. 한약재 추출물 첨가 농도가 높을수록 아질산염 소거능은 증가되었으며, III군과 IV군의 된장이 다른 I군과 II군의 된장보다 약간 높은 아질산염 소거능을 나타내었다. 수소공여능은 한약재 추출물 첨가 된장이 대조구 된장보다 약간 높은 경향을 나타내었으나 각 된장군 사이에는 큰 차이가 나타나지 않았다. 된장의 추출물을 사용하여 Str. mutans 및 Sal. enteritidis 등의 병원성 미생물에 대한 항균활성 및 fibrin배지 상에서의 혈전용해능은 대조구보다 모든 시험구에서 높게 나타났다. 이상의 결과로 한약재 추출물을 첨가하여 제조한 III군과 군은 색깔이 대조구와 유사하고, 기호도, 생리활성 및 항균활성 등이 우수하여 기능성이 강화된 새로운 전통된장의 개발 가능성이 높은 것으로 판단된다.

• 생약학회지
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• 제47권3호
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• pp.204-210
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• 2016

Phytochemical investigation of the 80% MeOH extract from the stems of Lagerstroemia indica resulted in the isolation of eighteen compounds; four norsesquiterpenes, fourteen phenolic derivatives. Their chemical structures were characterized by spectroscopic methods to be tachioside (1), isotachioside (2), 2,4,6-trimethoxyphenyl ${\beta}$-D-glucopyranoside (3), gallic acid 4-methyl ether (4), protocatechuic acid (5), gallic acid (6), vanillic acid (7), vanillin (8), 2-methoxy-5-hydroxymethyl-phenyl-1-O-(6"-galloyl)-${\beta}$-D-glucopyranoside (9), 2,4,6-trimethoxyphenol-1-O-${\beta}$-D-(6'-O-galloyl)-glucopyranoside (10), 4-hydroxy-3-methoxyphenyl-1-O-(6'-O-galloyl)-${\beta}$-D-glucopyranoside (11), vomifoliol (12), vomifoliol 9-O-${\beta}$-D-glucopyranoside (13), 6R,9R-3-oxo-${\alpha}$-ionol-9-O-${\beta}$-D-glucopyranoside (14), dihydrophaseic acid 4'-O-${\beta}$-D-glucopyranoside (15), ${\beta}$-hydroxypropiovanillone 3-O-${\beta}$-D-glucopyranoside (16), myrciaphenone A (17), and coumaric acid (18). Compounds 1-5 and 7-18 were isolated for the first time from this plant. Compounds 1-18 were investigated for their antioxidant properties using DPPH and ABTS radical scavenging capacity assay, $Fe^{2+}$ chelating, and FRAP assay. It was found that 4, 6, and 11 possessed the highest antioxidant capacities.

• 혜화의학회지
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• 제22권1호
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• pp.37-48
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• 2013

This study aims to summarize and makes a reference of anti-inflammatory activities of herbal medicines. In this process, this review collated papers of anti-inflammation-focused studies using herbal medicines in Oriental medical journals since 2003. Finally 221 papers were included and the type of materials, the type and effective classification of herbal medicines, the type of cells used in the experiments and the action and mechanisms of herbal medicine were analysed. The herbal medicines having the effects of decreasing fire and tonifying and nourishment were used the most. Most herbal medicines in this study can decrease proinflammatory cytokines, NO and prostaglandin 2 (PGE 2) production, inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression by regulating of nuclear factor kappa B (NF-${\kappa}B$) and/or mitogen activated protein kinases (MAPKs).

• 대한한의학회지
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• 제18권2호
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• pp.326-339
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• 1997

The Background and Purpose : Many herb-medicines are frequently used in China but they are not in Korea. It is required to prove them worthy to introduce into Korea and to find substitutes for them. The Objective and Methods : During stay in China as a Professor extraordinary, I investigated applications of Chinese modicines, books and theses. The Results and Conclusions : 1. In China the cheap herb-medicines are chosen preferentially and the classic rules of oriental medicine are truly observed. 2. in China it is impossible to prove virtue of ready made herb-medicines because constituents are not opened. 3. Commonly used herb-medicines are drug of clean away heat(淸熱藥) which are antinflammatories or anti-toxins. 4. Antitumorigenic effects was frequently reported but they don't get complete agreement also in China. 5. Herb-medicines which are frequently used in China but not in Korea have no significant differences from commonly used herb-medicines in Korea.

• Toxicological Research
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• 제13권4호
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• pp.327-330
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• 1997

Hepatitis, liver cirrhosis and liver cancer caused by viral infection are among the most prevalent causes of death in Korea. Several medicines have been in use despite their nonsatisfactory effects on these disease. Some herbal medicines put to use recently have not shown beneficial effects, either. This paper evaluates the effects of extracts from 10 traditional Korean herbal medicines on rats with hepatic damage induced by galactosamine. Rubus coreanus showed an anti-inflammatory effect as shown on the data of activities of serum transaminases.

• 동의생리병리학회지
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• 제18권4호
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• pp.1098-1101
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• 2004

This study was carried out to investigate the solubility of the ingredients of the kidney stone in the solution of the traditional oriental medicines. Calcium hydroxide, apatite and uric acid were chosen as the ingredients of the kidney stone. Plantaginis Semen, Lysimachiae Herba, Saururi Herba seu Rhizoma, Imperatae Rhizoma, Allium tuberosum Rottler were studied as the oriental medicines for the kidney stone. Calcium hydroxide had showed the very good solubility in the solution of Imperatae Rhizoma, the apatite had showed the good solubility in the solutions of Saururi Herba seu Rhizoma and Allium tuberosum Rottler. Uric acid had showed the mild solubility in the solution of Lysimachiae Herba and Saururi Herba seu Rhizoma.