• Journal of the Korean Chemical Society
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• v.8 no.2
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• pp.82-84
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• 1964

It has been pointed out that various substances such as "toxoalbumin", glycoside, choline or readily hydrolysable choline derivatives, alkaloid, lysolecithine etc. are associated with the toxicity of the infected grain. But animal tests and analysis of paper chromatography by author's indicated that a basic substance present in the concentrated extracts from the grain may neither be acetylcholine, betaine, nor choline. This problem still have to be examine further.

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2003.05a
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• pp.150-151
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• 2003

Benzoyl peroxide is a high production volume chemical, which was produced about 1,375 tons/year in Korea as of 2001 survey. Most of them are used as initiators in polymerization, catalysts in the plastics industry, bleaching agents for flour and medication for acne vulgaris. The substance is one of the sever chemicals of which human and environmental risks are being assessed by National Institute of Environmental Research under the frame of OECD SIDS Program. It has a melting point of 104-106 $^{\circ}C$ and has solubility of 9.1 mg/1 in water at 25 $^{\circ}C$. The substance was readily biodegradable (83 % after 21days) and had toxic effects to aquatic organisms. The range of 72 hr-EbC50 (biomass) for algae was 0.07-0.44 mg/1 and 48 hr-EC50 for daphnia was 0.07-2.91 mg/1. The LC50 of acute toxicity to fish was 0.24-2.0 mg/1. Although the toxic effects of benzoyl peroxide to aquatic organisms were investigated, environmental monitoring data were not studied. In this study, distribution of the chemical among multimedia environment was estimated using EQC model based on the physical-chemical properties to evaluate the risk of benzoyl peroxide in environment. In level I, II calculation the chemical was distributed to soil (68.3 %) and water (28.7 %). In level III calculation it was primarily distributed to soil (99.9 %) and overall residence time of 3.4 years was estimated. Benzoyl peroxide could be persistent in environment.

• Journal of the Korean Society of Safety
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• v.37 no.2
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• pp.10-17
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• 2022

Currently, in Korea, lower and upper tier qualifying quantities of the 97 substances requiring preparation for accidents have been designated. The information on the submission of chemical accident prevention management plan varies depending on whether the handling volume is above or below the lower or upper qualifying quantity. Because the criteria of the lower and upper qualifying quantities of substance requiring preparation for accidents are not stipulated in the Chemical Substances Control Act, this study attempted to establish a criterion through significance verification. In addition, the study investigated whether these qualifying quantities are related to the Globally Harmonized System of Classification and Labelling of Chemicals (GHS), toxic concentration endpoint, and National Fire Protection Association (NFPA). Finally, by comparing the risk categorization of the GHS, endpoint, and NFPA, it was evaluated whether the circulation-volume-based risk categorization of the substance requiring preparation for accidents that are in the top 13 is appropriate. The qualifying quantities of benzene, toluene, and sulfuric acid needed to be adjusted upward, while those of methyl alcohol and ammonia were adjusted downward from the current qualifying quantities. It is required to establish a quantified criterion that fully reflects the domestic situations in Korea and various indicators such as toxicity, physicochemical properties, and circulation volume for the qualified criterion of hazardous chemical substances. The study is expected to be helpful in establishing an efficient system by systematizing the criterion for qualifying quantity.

• Journal of Environmental Health Sciences
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• v.48 no.3
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• pp.183-194
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• 2022

Background: No study has examined the regulatory factors associated with fatal health problems due to the use of humidified disinfectants (HD) in South Korea. Objectives: This study aimed to identify and discuss the deficiencies and limitations found in the Toxic Chemical Control Acts (TCCA) that failed to prevent the health risk of chemicals in HD products. Methods: The South Korean TCCA was reviewed focusing on acts in operation from 1994 through the end of 2011, the period when HD was allowed in manufacturing and marketing. Results: The TCCA was the act intended to regulate the toxicity of chemicals in HD products. We found the TCCA to lack three key legal clauses which would have been essential to controlling the health risk of HD. First, there was the exemption of toxic and hazard testing for existing chemicals, including chloromethylisothiazolinone (CMIT), methylisothiazolinone (MIT), and benzalkonium chloride (BKC). Secondly, there were no articles requiring industry to provide animal inhalation test result for polymers such as polyhexamethylene guanidine (PHMG) and Oligo(2-)ethoxyethoxyethyl guanidine chloride (PGH). Finally, there was a lack of articles on examining the risk of products as well as on addressing changes in the usage of products. These articles were found to be generally provided in the US Toxic Substance Chemical Act (TSCA) and the EU Registration, Evaluation and Authorization of Chemicals (REACH). Conclusions: In conclusion, the Ministry of Environment of South Korea had not updated key articles for regulating hazardous chemicals, causing large-scale health problems due to HD which had been fundamentally addressed in chemical-related acts in other countries.

• Journal of the Korean Society of Safety
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• v.32 no.1
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• pp.47-52
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• 2017

Chemical accidents occur by a variety of causes and aspects. Accident preparedness substances (APS) are defined by toxic chemicals highly likely to cause accidents due to their high acute toxicity, explosiveness or likely to cause severe damage where a chemical accident occurs among the chemicals. APS is designated and announced by Presidential Decree. However, chemical accidents occurred for recent 7 years were arisen mainly from non-accident preparedness substances, and only 24 species were included as chemical accident trigger among total 69 APS. In addition, APS were designated in 2014 and the list has not been updated since then although it needs to be amended in several aspects. Accordingly, this study analyzes the necessity of modification of APS management, and presents improved plans.

• Journal of the Korean Society of Safety
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• v.35 no.6
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• pp.15-24
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• 2020

With the development of the chemical industry, the chemical accident is increasing every year, thereby increasing the risk of accidents caused by chemicals. The Ministry of Environment provides the criteria for determining shelter-in-place or outdoor evacuation by material, duration of accident, and distance from the toxic substance leak. However, it is hard to say that the criteria for determining the transition point are not clear. Transition point mean the time that evacuation method is switched from shelter-in-place to outdoor evacuation. So, the purpose of this study was to calculate appropriate transition point by comparing the cumulative toxic load. Namdong-gu in Incheon Metropolitan City was finally selected as the target area, considering the current status of the population of Incheon Metropolitan City in 2016 and the statistical survey of chemicals in 2016. The target materials were HCl, HF, and NH₃. Modeling was simulated by ALOHA and performed assuming that the entire amount would be leaked for 10 min. Residents' evacuation scenarios were assumed to be shelter-in-place, immediate outdoor evacuation, and outdoor evacuation at an appropriate time after shelter-in-place. Based on the above method, the appropriate transition point from residents located in A(800 m away), B(1,200 m away), C(1,400 m away) and D(2,200 m away) was identified. In HCl, appropriate transition point was after 15 min, after 16 min, after 17 min, after 20 min in order by A, B, C and D. In HF, appropriate transition point was before 1 min or after 16 min, before 4 min or after 19 min, before 5 min or after 20 min, before 14 min or after 26 min in order by A, B, C and D. In NH₃, appropriate transition point at A was before 4 min or after 16. Others are not in chemical cloud. This study confirmed the transition point to minimize the cumulative toxic load can be obtained by quantitative method. Through this, it might be possible to select evacuation method quantitatively that cumulative toxic load are minimal. In addition, if the shelter-in-place is maintained without transition to outdoor evacuation, the cumulative toxic load will increase more than outdoor evacuation. Therefore, it was confirmed that actions to reduce the concentration of chemicals in the room were necessary, such as conducting ventilation after the chemical cloud passed through the site.

• Journal of the Korean Institute of Gas
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• v.27 no.4
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• pp.43-49
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• 2023

Hydrofluoric acid is a less acidic substance than hydrochloric acid, nitric acid, and sulfuric acid, but it is one of the most dangerous substances for humans. In recent years, it has become an indispensable substance in industries such as chemical plants and the semiconductor industry, and although it is a threat to the human body, its use is increasing for various purposes, and the amount of use is constantly increasing due to the expansion and development of the industry. The dangers of hydrogen fluoride have been highlighted since the 2012 accident, which led to a more than fivefold increase in management standards for handling facilities. Hydrogen fluoride converts to hydrofluoric acid when exposed to the air, which can be fatal to humans. This study simulates the effects of a release of a toxic substance in the workplace, even though a protection layer has been provided to minimize the damage caused by the released toxic substance, and recommend ways to control the risk to workers in the event of a release in the workplace.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.216-223
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• 2017

Chemicals are an indispensable element of modern society to the extent that more than 15 million species are commercially available worldwide. However, among them are chemicals whose toxicityposes a threat to public health and the environment, as illustrated by past cases of chemical accidents, which revealed their danger to human life. Chemical accidents can spread and cause huge damage in a short time because of their characteristics. Therefore, it is important to do as much as possible to prevent them in advance and to respond promptly after an accident. The legal system pertaining to domestic chemical substances is the "Toxic Chemical Control Act", which is made up of the "Act on the Registration and Evaluation of Chemicals" and the "Chemical Control Act" since 2015. Under this law, the Comprehensive Chemical Information System and Chemical Substance Data Processing system were established and are still operating;however, chemical accidents are still occurring. These systems are comprehensive information systems aimed at providing chemical information rather than acting as chemical response systems, which has limited the effectiveness of accident response. This study is intended to analyze the information management systems, response management systems and the basis of chemical substance management support for hazardous chemicals and suggest ways to improve the legal system for developing and operating chemical response systemswithin a municipality.

• Environmental and Resource Economics Review
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• v.17 no.3
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• pp.31-59
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• 2008

This paper is intended to analyze the toxic substances transmission between South Korea and U.S. through international trade, based on 2000 international input-output data and both country's toxic substances. According to result, The high TEI sectors are metal, chemical and general machinery in Korea, and the high TEI sectors of America are electric & electronics, Chemicals, Rubber and Plastics. Korea's export structure to America is more pollutant than America's export structure to Korea.

• Proceedings of the IEEK Conference
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• 2001.10a
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• pp.711-714
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• 2001

A new technology to make fluoride gas such as NF$_3$contained in the exhaust gas from semiconductor manufacturing plants convert directly into a harmless substance have been established and new concept on the disposal treatment of global warming gases were presented. Experimental results verify that the chemical reactions can be take place at substantially lower temperature of 80-40$0^{\circ}C$ as compared with the combustion treatment method. Reaction product is mainly metal fluoride which is a harmless and a valuable chemical material as one of new resources. The other favorable characteristics are that the continuous treatment is possible at a low temperature under atmospheric pressure. Furthermore this process is compact, easily controllable and safely operable at low running cost. This paper concerns with a new harmless disposal treatment of toxic global warming gas.