• 대한전자공학회논문지SP
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• 제48권3호
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• pp.62-70
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• 2011

CFA(Color Filter Array)를 사용하는 이미지 센서에서는 컬러정보를 획득하기 위해 디모자이킹 과정을 거치게 된다. 이상적인 컬러특성을 갖는 이미지센서에 적용되는 디모자이킹 방식은 실제로 이미지센서에 바로 적용할 경우 올바른 동작을 장담할 수 없는데, 이는 센서마다 그 특성이 다르기 때문이다. 따라서 디모자이킹 알고리즘을 적용할 때에는 각 센서의 특성에 따라서 다르게 적용이 되어야만 한다. 본 논문에서는 Honeycomb CFA방식을 사용하는 CCD 이미지 센서에서 사용되는 디모자이킹 알고리즘을 제안하고, 실제 이미지 센서(CBN385B)의 컬러특성을 고려하여 필터의 계수를 보정함으로써 개선된 성능을 갖는 디모자이킹 알고리즘을 제안한다. 또한 디모자이킹 알고리즘을 하드웨어로 구현하여 그 성능을 비교한다. 제안한 알고리즘을 검증하기 위한 방법으로 전체 ISP시스템을 구현 했으며, 성능을 확인할 지표로 알고리즘 자체성능은 PSNR로 이미지센서의 필터특성의 적용의 결과는 RGB분포도를 이용하였다. 결과적으로 기존의 방법에 비해 PSNR 값이 4~8dB 증가하였으며, 실제 이미지센서(CBN385B)에서 Red 성분으로 편중된 현상도 제거하였다. 또한 하드웨어 설계를 통해 소프트웨어적인 연산의 복잡성을 해결하였으며 검증을 위해 Spartan-3E FPGA가 사용되었다. 총 게이트 수는 45K개이며 25 frame/sec의 속도를 보였다.

• Investigative Magnetic Resonance Imaging
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• 제25권3호
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• pp.164-171
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• 2021

Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized by magnetic resonance imaging. To overcome the unsatisfactory inter-observer reliability of visual evaluation, quantitative brain volumetry has been developed and widely investigated for the diagnosis of MCI and AD. The aim of this study was to assess the prediction accuracy of quantitative brain volumetry using a fully automated segmentation software package, NeuroQuant^®, for the diagnosis of MCI. Materials and Methods: A total of 418 subjects from the Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer's Disease cohort were included in our study. Each participant was allocated to either a cognitively normal old group (n = 285) or an MCI group (n = 133). Brain volumetric data were obtained from T1-weighted images using the NeuroQuant software package. Logistic regression and receiver operating characteristic (ROC) curve analyses were performed to investigate relevant brain regions and their prediction accuracies. Results: Multivariate logistic regression analysis revealed that normative percentiles of the hippocampus (P < 0.001), amygdala (P = 0.003), frontal lobe (P = 0.049), medial parietal lobe (P = 0.023), and third ventricle (P = 0.012) were independent predictive factors for MCI. In ROC analysis, normative percentiles of the hippocampus and amygdala showed fair accuracies in the diagnosis of MCI (area under the curve: 0.739 and 0.727, respectively). Conclusion: Normative percentiles of the hippocampus and amygdala provided by the fully automated segmentation software could be used for screening MCI with a reasonable post-processing time. This information might help us interpret structural MRI in patients with cognitive impairment.

• 산업경영시스템학회지
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• 제41권1호
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• pp.102-109
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• 2018

This paper seeks to present a multi-control method that can contribute to effective control of the production line with multiple bottleneck processes. The multi-control method is the production system that complements shortcomings of CONWIP and DBR, and it is designed to determine the raw material input according to the WIP level of two bottleneck processes and WIP level of total process. The effectiveness of the production system developed by applying the multi-control method was verified by the following three procedures. Raw material input conditions of the multi-control method are as follows. First, raw materials are go into the production line when the number of the total process WIP is lower than established number of WIP in total process and first process is idle. Second, raw materials are introduced when the number of WIP of two bottleneck processes is lower than the established number of WIP of each bottleneck process. Third, raw materials are introduced when the first process and in front of bottleneck process are idle even if the number of WIP in the total process is less than established number of WIP of the total process. The production line with two bottleneck processes was selected as the condition for production environment, and the production process modeling of CONWIP, DBR and multi-control production method was defined according to the production condition. And the optimum limited WIP level suitable for each system was obtained by applying a genetic algorithm to determine the total limited number of WIP of CONWIP, the limited number of WIP of DBR bottleneck process, the number of WIP in the total process of multi-control method and the limited number of WIP of bottleneck process. The limited number of WIP of CONWIP, DBR and multi-control method obtained by the genetic algorithm were applied to ARENA modeling, which is simulation software, and a simulation was conducted to derive result values on the basis of three criteria such as production volume, lead time and number of goods in-progress.

• 대기
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• 제17권4호
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• pp.339-348
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• 2007

Global Environment Laboratory at Yonsei University in Seoul ($37.57^{\circ}N$, $126.95^{\circ}E$) has carried out the ozone layer monitoring program in the framework of the Global Ozone Observing System of the World Meteorlogical Organization (WMO/GAW/GO3OS Station No. 252) since May of 1984. The daily measurements of total ozone and the vertical distribution of ozone amount have been made with the Dobson Spectrophotometer (No.124) on the roof of the Science Building on Yonsei campus. From 2004 through 2006, major parts of the manual operations are automated in measuring total ozone amount and vertical ozone profile through Umkehr method, and calibrating instrument by standard lamp tests with new hardware and software including step motor, rotary encoder, controller, and visual display. This system takes full advantage of Windows interface and information technology to realize adaptability to the latest Windows PC and flexible data processing system. This automatic system also utilizes card slot of desktop personal computer to control various types of boards in the driving unit for operating Dobson spectrophotometer and testing devices. Thus, by automating most of the manual work both in instrument operation and in data processing, subjective human errors and individual differences are eliminated. It is therefore found that the ozone data quality has been distinctly upgraded after automation of the Dobson instrument.

• 대한의용생체공학회:의공학회지
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• 제28권1호
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• pp.108-116
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• 2007

Recently, it has been reported that the posterior stabilized implant, which is clinically used for the total knee replacement (TKR), may have failure risk such as wear or fracture by the contact pressure and stress on the tibial post. The purpose of this study is to investigate the influence of the mal alignment of the posterior stabilized implant on the tibial post by estimating the distributions of contact pressure and von-Mises stress on a tibial post and to analyze the failure risk of the tibial post. Finite element models of a knee joint and an implant were developed from 1mm slices of CT images and 3D CAD software, respectively. The contact pressure and the von-Mises stress applying on the implant were analyzed by the finite element analysis in the neutral alignment as well as the 8 malalignment cases (3 and 5 degrees of valgus and varus angulations, and 2 and 4 degrees of anterior and posterior tilts). Loading condition at the 40% of one whole gait cycle such as 2000N of compressive load, 25N of anterior-posterior load, and 6.5Nm of torque was applied to the TKR models. Both the maximum contact pressure and the maximum von-Mises stress were concentrated on the anterior-medial region of the tibial post regardless of the malalignment, and their magnitudes increased as the degree of the malalignment increased. From present result, it is shown that the malalignment of the implant can influence on the failure risk of the tibial post.

• Earthquakes and Structures
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• 제8권5호
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• pp.1255-1276
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• 2015

The importance of considering soil-structure interaction effect in the analysis and design of RC frame buildings is increasingly recognized but still not penetrated to the grass root level owing to various complexities involved. It is well established fact that the soil-structure interaction effect considerably influence the design of multi-storey buildings subjected to lateral seismic loads. The shear walls are often provided in such buildings to increase the lateral stability to resist seismic lateral loads. In the present work, the linear soil-structure analysis of a G+5 storey RC shear wall building frame resting on isolated column footings and supported by deformable soil is presented. The finite element modelling and analysis is carried out using ANSYS software under normal loads as well as under seismic loads. Various load combinations are considered as per IS-1893 (Part-1):2002. The interaction analysis is carried out with and without shear wall to investigate the effect of inclusion of shear wall on the total and differential settlements in the footings due to deformations in the soil mass. The frame and soil mass both are considered to behave in linear elastic manner. It is observed that the soil-structure interaction effect causes significant total and differential settlements in the footings. Maximum total settlement in footings occurs under vertical loads and inner footings settle more than outer footings creating a saucer shaped settlement profile of the footings. Each combination of seismic loads causes maximum differential settlement in one or more footings. Presence of shear wall decreases pulling/pushing effect of seismic forces on footings resulting in more stability to the structures.

• Asian-Australasian Journal of Animal Sciences
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• 제21권3호
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• pp.331-339
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• 2008

The genetic structure and diversity of 15 Chinese indigenous chicken breeds was investigated using 29 microsatellite markers. The total number of birds examined was 542, on average 36 birds per breed. A total of 277 alleles (mean number 9.55 alleles per locus, ranging from 2 to 25) was observed. All populations showed high levels of heterozygosity with the lowest estimate of 0.440 for the Gushi chickens, and the highest one of 0.644 observed for Wannan Three-yellow chickens. The global heterozygote deficit across all populations (FIT) amounted to 0.180 (p<0.001). About 16% of the total genetic variability originated from differences between breeds, with all loci contributing significantly to this differentiation. An unrooted consensus tree was constructed using the Neighbour-Joining method and pair-wise distances based on marker estimated kinships. Two main groups were found. The heavy-body type populations grouped together in one cluster while the light-body type populations formed the second cluster. The STRUCTURE software was used to assess genetic clustering of these chicken breeds. Similar to the phylogenetic analysis, the heavy-body type and light-body type populations separated first. Clustering analysis provided an accurate representation of the current genetic relations among the breeds. Remarkably similar breed rankings were obtained with all methods.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7759-7763
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• 2015

Background: Leukemia accounts for 8% of total cancer cases and involves all age groups with different prevalence and incidence rates in Iran and the entire world and causes a significant death toll and heavy expenses for diagnosis and treatment processes. This study was done to evaluate epidemiology and morphology of blood cancer during 2003-2008. Materials and Methods: This cross-sectional study was carried out based on re-analysis of the Cancer Registry Center report of the Health Deputy in Iran during a 6-year period (2003 - 2008). Statistical analysis for incidence time trends and morphology change percentage was performed with joinpoint regression analysis using the software Joinpoint Regression Program. Results: During the studied years a total of 18,353 hematopoietic and reticuloendothelial system cancers were recorded. Chi square test showed significant difference between sex and morphological types of blood cancer (P-value<0.001). Joinpoint analysis showed a significant increasing trend for the adjusted standard incidence rate (ASIR) for both sexes (P-value<0.05). Annual percent changes (APC) for women and men were 18.7 and 19.9, respectively. The most common morphological blood cancers were ALL, ALM, MM and CLL which accounted for 60% of total hematopoietic system cancers. Joinpoint analyze showed a significant decreasing trend for ALM in both sexes (P-value<0.05). Conclusions: Hematopoietic system cancers in Iran demonstrate an increasing trend for incidence rate and decreasing trend for ALL, ALM and CLL morphology.

• 대한영양사협회학술지
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• 제26권4호
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• pp.243-253
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• 2020

The purpose of this study was to set new guidelines for adenosine triphosphate (ATP) bioluminescence hygiene monitoring of distribution trays at children's foodservices. Five dietitians visited 223 foodservices (95 institutional, 128 small) to examine whether they adhered to the norms of 'Keeping distribution tray sanitary by washing/sanitizing' and 'Performing food distribution in a clean and appropriate way'. In this visit, dietitians swabbed 100 ㎠ area of the distribution trays twice, once for obtaining ATP measurements and the second time for Aerobic Plate Counts (APC) using 3M Petrifilm Plates. Chi-square test and ANOVA were applied using SPSS 23.0 software. SPSS 23.0 was used to conduct graphical and statistical analysis of the raw data of ATP measurements, which were further transformed by a Box-Cox transformation. The mean of APC from all the subjects inspected was 3.8×10²±2,102.0 CFU/100 ㎠. A total of 208 (93.3%) trays were observed within the acceptable limits of APC (Pass<5.0×10² CFU/100 ㎠). APCs taken at institutional foodservices showed significantly lower levels (1.4×10²±600.0 CFU/100 ㎠, P<0.01) compared to the small foodservices (5.5×10²±2,718.7 CFU/100 ㎠). No significant differences were observed between the two groups in ATP measurements and in the performance rate of 2 checklist items. As against the 93.3% APC adequacy from the total subjected inspection, total ATP adequacy (Pass≤300 RLU/100 ㎠) was only 71.7%. Therefore, more practical guidelines should be prepared for the assessment of the hygiene of distribution trays. In the graphical and statistical analysis, levels below 250 RLU/100 ㎠ was considered 'Pass', while equal to or greater than 350 RLU/100 ㎠ was considered 'Fail' for distribution trays.

• 한국작물학회:학술대회논문집
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• 한국작물학회 2017년도 9th Asian Crop Science Association conference
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• pp.130-130
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• 2017

Sorghum bicolor is considered as copper-tolerant species. The present study was conducted to understand the copper tolerance mechanism in Sorghum seedling roots. Morphological and effects of Cu on other interacting ions were observed prominently in the roots when the plants were subjected to different concentrations (0, 50, and $100{\mu}M$) of $CuSO_4$. However, the morphological characteristics were reduced by Cu stress, and the most significant growth inhibition was observed in plants treated with the highest concentration of $Cu^{2+}$ ions ($100{\mu}M$). In the proteome analysis, high-throughput two-dimensional polyacrylamide gel electrophoresis coupled with MALDI-TOF-TOF mass spectrometry was performed to explore the molecular responses of Cu-induced sorghum seedling roots. In two-dimensional silver-stained gels, a total of 422 differentially expressed proteins (${\geq}1.5-fold$) were identified using Progenesis SameSpot software. A total of 21 protein spots (${\geq}1.5-fold$) from Cu-induced sorghum roots were analyzed by mass spectrometry. Of the 21 differentially expressed protein spots from Cu-induced sorghum roots, a total of 10 proteins were up-regulated, and 11 proteins were down-regulated. The abundance of the most identified protein species from the roots that function in stress response and metabolism was significantly enhanced, while protein species involved in transcription and regulation were severely reduced. The results obtained from the present study may provide insights into the tolerance mechanism of seedling roots in Sorghum.