• IMMUNE NETWORK
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• v.2 no.1
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• pp.1-5
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• 2002

Estimated number of adults and children newly infected with HIV-1 during 2001 alone is 5 million in total. An effective vaccine, in addition to education & public health approaches, has been believed to be the best option to stop the HIV-1 transmission, especially for developing countries. Among AIDS vaccine candidates, DNA vaccine is relatively safe and, in a certain extent, mimics some attributes of live attenuated vaccine, with regard to in vivo gene expression & the type of immunity induced. We recently demonstrated that DNA vaccines expressing SIVmac239 structural and regulatory genes, augmented with coadministration of IL-12 mutant induced the strongest T cell responses, resulting in low to undetectable setpoint viral loads, stable $CD4^+$ T cell counts, and no evidence of clinical diseases or mortality by day 420 after challenge. This finding is the second demonstration, following the protective result of live attenuated SIV vaccine in SIVmac-rhesus monkey model, which was known to have safety problem. So, our DNA vaccines could give a significant impact on HIV-1 epidemic by slowing or stopping the spread of HIV-1, leading to eventual eradication of HIV-1 and AIDS in the population.

• Journal of the Korean Electrochemical Society
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• v.5 no.4
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• pp.216-220
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• 2002

The effects of electrolytes on electrochemical behavior from an oil thin layer interposed between a graphite electrode and an aqueous solution phase were examined. A hydrophobic electroactive species, tetrachloro-1,4-benzoquinone (TCQ), in a benzonitrile (EN) layer was employed to study ion transfer properties across the BN-water interface. Experimental results showed that hydrophobic cations as well as anions could be successfully used as ionic charge carriers. The addition of various salts into either the oil layers or the aqueous solutions offers deeper insight for the electrochemistry of the liquid thin layer system. When aqueous perchloric acid is interfaced with the BN films, the perchlorate ion of tetrahexylammonium perchlorate (THAP) substantially suppresses the dissociated proton concentration in the layer by the common ion effect while there is only a little change in the total acid concentration. Further approach by theoretical calculation makes it possible to quantitatively understand the effect of the electrolytes to the electrochemical responses of TCQ, which were previously reported (Anal. Chem. 73, 337 (2001)).

• Computational Structural Engineering
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• v.2 no.2
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• pp.53-62
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• 1989

In recent times, the subterranean caverns for storing crude oils and oil products are increasingly needed. The elasto-VIScoplastic DYNamic finite element analysis program(VISDYN) has been developed in order to investigate dynamic responses of the storage cavity. And validity of the program is studied through a numerical example. Mohr-Coulomb yield criterion is adopted and associated flow rule is assumed. Geometrically nonlinear behaviour is taken into account using a total Lagrangian formulation. In dynamic deformation reponses, the difference between the steady state displacements and the unsteady state ones by the static analysis can be neglected.

• Earthquakes and Structures
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• v.9 no.3
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• pp.625-637
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• 2015

It is usual in design and assessment of structures to isolate the effects of vertical and horizontal excitations by ignoring their coupling effects. In this situation, total structural response is obtained by employing the well-known combination rules whereby independent assumed response components of earthquakes are combined. In fact, the effects of the simultaneity of the ground motion components are ignored. In this paper, the effect of vertical excitation on horizontal response of structures, the coupling of vertical and horizontal responses, has been evaluated. A computer program is prepared to perform nonlinear dynamic analysis based on the derived governing equations of coupled motions. In the case of simultaneous excitation the results show significant increases in spectral displacement in some periods of vibration in comparison to only horizontally excited systems. Moreover, whenever ratio of the vertical peak ground acceleration to horizontal one become larger, the significant increase in horizontal spectral displacements are observed.

• Korean Journal of Plant Resources
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• v.24 no.6
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• pp.733-740
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• 2011

For the current study, 2,000 questionnaire sheets were printed and distributed while at the same time postal questionnaires were also conducted. The questionnaire survey was conducted July 25 through September 25, 2008, whereby 206 copies of desirable responses were secured. Analysis of the survey made it possible to grasp the overall current status and prospects of the mountain-grown ginseng business, and the level of technology required for cultivating mountaingrown ginsengs. It was learned that, with no legal and institutional arrangements now in force, no precise facts and figures concerning the total area cultivated and the quantity produced are currently available, and that the products are being marketed under the table. Under such circumstances, it is high time for the mountain-grown ginseng cultivation business to contribute to the promotion of incomes of the farming households and the generation of national wealth by developing the business into a systematic industry. This study conducted a survey on the current status of mountain-grown ginseng producers and of their production, thereby contributing to the introduction of policies for mountain-grown ginsengs.

• The Journal of Information Systems
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• v.15 no.1
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• pp.21-48
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• 2006

Recently the development of information technology and the emergence of electronic commerce have changed the model of purchase behavior in customers. This research aims to enhance the reliability of the result compared to the existing studies in internet shopping mall, and to find out the influence that logistics service quality elements has on customer satisfaction and that customers satisfaction has on the repurchase intention and word of mouth intention. To do so, prior researchs on the logistics service quality, customer satisfaction, repurchase intention and word of mouth intention was widely reviewed and the relationship between logistics service quality elements and customer satisfaction, and between customer satisfaction and repurchase intention and word of mouth intention were empirically tested. A total of 256 responses were received and analyzed from internet shopping mall. The analyses showed partial support for the affirmative effect of logistics service quality, customer satisfaction and post-purchasing behaviors in the internet shopping mall.

• The Journal of Information Systems
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• v.16 no.4
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• pp.195-221
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• 2007

In this study, we investigate the effect of social presence and affection on the UCC service participation. We have conducted a face-to-face survey along with an e-mail survey and obtained a total of 329 responses. The findings show that social presence has a significant impact on pleasure and arousal. Social presence in turn show a positive impact on participation in the UCC service. Meanwhile, pleasure shows a negative effect on the UCC service participation, while arousal very strongly and positively affects the UCC service participation. The significance of this study can be found in that it empirically demonstrates the importance of social presence and affection in promoting the UCC service.

• Speech Sciences
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• v.11 no.4
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• pp.151-161
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• 2004

The characteristics of generative naming ability between fluent aphasiacs and non-fluent aphasics were investigated for 10 fluent aphasics (6 Wernicke's and 4 conduction type) and 10 non-fluent aphasics (6 Broca's and 4 transcortical motor type). Subjects were given 2 types of generative naming task and asked to generate lists of words to categorical ('animal', 'things at a supermarket') and phonetic ('ㄱ', 'ㅇ', 'ㅅ') cues. The total numbers of correct and incorrect response and error type ratios were calculated. The results of the present study were as follows: (1) Fluent aphasics had higher generative naming scores than non-fluent aphasics. (2) A remarkable dissociation between performance on categorical and phonetic cue in both aphasic groups was observed. Both aphasic groups produced a large number of responses in the categorical cue. (3) There was no significant group-difference in the error type. (4) Any correlation between generative naming and confrontation naming in K - WAB was not found.

• Proceedings of the Korean Society of Computer Information Conference
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• 2016.01a
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• pp.147-148
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• 2016

The purpose of this paper is to investigate the diffusion process of mobile internet use in Korea and to explore the determinants driving MIU. A survey was conducted to collect data to empirically assess the research model. In total, 543 usable responses were collected using a questionnaire derived from previous research. Both the structural equation model and partial least squares were used to study the model concerning different user groups. Findings, The results indicate that there are significant differences in the users' perceptions of mobile internet usage during its different innovation diffusion stages. Of the determinants, perceived enjoyment is the most important predictor of mobile internet use. In addition to motivating users by making services more enjoyable, the findings suggest that practitioners should take the differences of adopter groups into account. Making the mobile internet easy to use and compatible with users' lifestyles would promote the use of technology as well.

• Journal of Microbiology
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• v.37 no.1
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• pp.1-9
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• 1999

The Biolog redox technology was carried out for evaluation of acidification effect on microbial communities at each stage of pH gradient microcosm. While the number of heterotrophic bacterial population and activities of extracellular enzyme decreased as the pH decreased, the number of total bacteria in the microcosm was not affected. The average color development of sample at each pH-gradient showed a sigmoidal curve, and at higher pH, more overall color development appeared in Biolog plates. Average color development value in Biolog plates was stabilized at 50 hours as an optimum incubation time. The color production in the Biolog plates was caused by cell density at above pH 5.0, but by cell activity below pH 4.0. Principal component analysis of color responses revealed distinctive patterns among the pH-gradient microcosm samples.