• The Journal of the Acoustical Society of Korea
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• v.24 no.3
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• pp.127-132
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• 2005

Transducers for implantable hearing aids need to be small and to have good performance in frequency responses and vibration properties. From this viewpoint, we Proposed a multi-layer actuator with the piezoelectric single crystal, PMN-PT. for the implantable hearing aid. and verified its adequacy through finite element analyses and experiments. PMN-PT multi-layer actuator samples were fabricated by stacking fourteen layers of the PMN-PT crystal. Each layer were $0.2{\cal}mm$ thick and the actuator sample was $2.8{\cal}mm$ thick in total. We evaluated the performance of the PMN-PT actuator through impedance analyses and vibration displacement measurements, and compared the result with that of a PZT actuator. Results of all the process confirmed the feasibility of the PMN-PT actuator as a good transducer for an implantable hearing aid.

• Journal of Ginseng Research
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• v.30 no.1
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• pp.1-7
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• 2006

Ceramide has been involved in celt death and acted as a lipid mediator of stress responses. Elevation of ceramide level was reported to occur in oxidative stress and lead to cell death in many cell types. This study was undertaken to elucidate a protective role of ginsenoside Rgl in cell death induced by oxidative stress. When LLC-PK1 cells were treated with $H_2O_2$ at a concentration of $400{\mu}M$ for 5 hr, cell death was observed and a released LDH activity indicative of cytotoxicity was Increased. $H_2O_2$ exposure to LLC-PK1 cells was shown to elevate the content of total ceramide by approximately 200% compared to control cells. Ceramide level was hypothesized to be a key to a reversal of cell death to survival. Ginsenoside Rgl at the concentrations ranging from 12.5 to $250{\mu}M$ protected LLC-PK1 cells from cell death induced by $H_2O_2\;at\;400{\mu}M$ for 5 hr, and decreased the ceramide level relative to $H_2O_2$. Ginsenoside Rgl inhibited neutral human ceramidase by 71% of controls, while sphingomyelinase was not inhibited. These results suggest that ginsenoside Rgl show the protection against cell death via the modulation of ceramide metabolism, and ceramide may be a promising therapeutic target for human diseases related to cell death.

• Journal of Plant Biology
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• v.17 no.1
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• pp.15-21
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• 1974

The most commonly grown economical and flue-cured tobacco cultivar Yellow Special A was used in pot-culture tests in order to study Ethrel (2-chloroethyl phosponic acid) effects on accelerating maturity of tobacco leaves in relation to the most adequate level of the chemical useful for field growing, nitrogen level in soil for the most pronounced response, and the most suitable spray period during the growth stages of pre-, post- and topping periods. The following conclusions, thus, were obtained from the present studies; 1. 500ppm Ethrel spray was reconfirmed to be adequate in the practical applications, although the extent of yellow-ripening of tobacco leaves was increased as the Ethrel level increased. The highest leevel treated resulted in causing chemically damaged lesions on leaves and early defoliation. 2. Ethrel-treated leaves showed deeper yellowish tinge to them than those without treatment, while different levels of the chemcial had less influence on the tinge. 3. An adequate level of nitrogen supply to plants favored the Ethrel response, whereas either very low or high level of nitrogen in the soil lowered the chemical effect on accelerating the yellow-ripening. When carbohydrates versus total nitrogen ratio became relatively high, the condition brought out some outstanding Ethrel effects. 4. Chlorophyll level of leaves increased as soil applications of nitrogen level increased, and that also increased carotenoid level of the tobacco leaves. Ethrel-treated leaves showed deeper orange tinge than those without treatment, while the highest level of nitrogen application showed the deepest orange tinge to tobacco leaves. 5. Pre-topping treatment (12 days before topping and flowering) resulted in almost no Ethrel response, and that treatment right on the day of topping, showed response of yellow-leaf ripening at nearly bottom-half leaves of a tobacco plant. The post-topping treatment (12 days after topping) made plants showing full response of Ethrel from bottom to the top leaves of tobacco plant in accelerating the leaf maturity. 6. The extent of Ethrel responses on accelerating yellow-ripening of tobacco leaves was discussed for the modifying influences brought about by certain environmental factors. Discussions were also made about the possible practical applications (particularly for pre-rice planting) and quality difference that may be caused by such growth environments.

• Journal of rehabilitation welfare engineering & assistive technology
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• v.9 no.3
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• pp.209-214
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• 2015

The purpose of this study was to examine (1) the influence of the word-prediction function on the sentence generation speed and (2) the necessity, convenience, and satisfaction of the word-prediction function of the AAC keyboard. A total of 10 adults with cerebral palsy participated and the word-prediction function of the Korean high-tech AAC device called "MyTalkie Smart" keyboard was used for this study. Participants were required to generate sentence as voice outputs using a word-prediction function and letters direct-input function respectively, then they were required to evaluate the necessity, convenience, and satisfaction using a five-point Likert scale. Other user requirements were examined using a free feedback. The results of this study presented that the sentence generation speeds were faster when participants used a word-prediction function than using a letters direct-input function. However, there was no statistically significant difference between these two input methods, and it might be due to the lack of time to practice the new device. Participants showed positive responses for the necessity, convenience, and satisfaction of the word-prediction function.

• Journal of Digital Convergence
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• v.15 no.9
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• pp.479-486
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• 2017

The purpose of this study is to analyze the preference and value of consumers through the package design of cosmetics with the concept of cause branding, and to propose a package design that can satisfy consumers' needs. I have recruited an experimental group that emphasizes the importance of package design in purchasing cosmetics. And Survey and in-depth interviews were conducted by comparing cause brand's product with general brand's product. In the first experiment, the items were classified into cognitive, emotional, and behavioral responses and a total of 31 subjects were surveyed. In the second experiment, six interviewees were interviewed through a questionnaire prepared by extracting 4 items from Sheth 's consumption value standard. As a result of the experiment, consumers preferred a design that can quickly and accurately grasp the information of the product. Especially, it is not easy to know whether it is a cause brand's product. So It should be stated in the package how it will be socially beneficial.

• Journal of Digital Convergence
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• v.15 no.1
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• pp.97-108
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• 2017

Web 2.0 paradigm and technologies allow users to contribute their information voluntarily and actively to online community. This paper aims to investigate key determinants of information contribution in online communities. We come up with the research model and proposed hypotheses on the basis of intensive literature review on motivation theory, information literacy, and self expression. Using survey response date collected from those who have ever experienced in uploading or providing information on online community such as social media. A total of 262 survey responses were used to test research hypotheses. The results show that self expression motive influences on information representation capability(IRC) and information contribution. The impact of Information literacy on IRC is found to be significant, and IRC is positively related to information contribution. In addition, approval motive is proven to be key determinant of IRC and information contribution. Some practical implications of these findings are discussed.

• Animal cells and systems
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• v.1 no.1
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• pp.115-121
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• 1997

To precisely analyze the role of ovarian steroids in the regulation of laminin chain gene expression in mouse uterine tissues, the ovariectomized mouse model was used. Ovariectomized mice received a single injection of steroid hormones and total RNA was isolated from whole uterine tissues. Messenger RNA levels of each laminin chain (A, 81, and 82) were determined by competitive RT-peR procedures. Estradiol decreased mRNA levels of laminin 81 chain about two-fold, and 82 chain rather moderately. Estradiol-induced inhibition of laminin 81 and 82 chain mRNA levels were completely blocked by pretreatment with estrogen receptor antagonist tamoxifen. Estriol, a short acting estrogen which cannot induce hyperplastic responses of rodent uterine tissues, also showed an inhibitory effect on 81 and 82 chain mRNA levels, while estrone, an inactive estrogen, failed to influence either 8 chain mRNA levels. Effects of steroids on A chain mRNA level were quite different from those on 8 chains. Laminin A chain mRNA level was slightly increased by estradiol treatment, but negatively affected by progesterone. Progesterone treatment greatly increased both 8 chain mRNA levels, but slightly decreased A chain mRNA level compared to the control. The effect of progesterone on laminin chain-specific mRNA levels was further increased by co-injection of estradiol in a time-dependent manner. Progesterone-induced 81 and 82 chain mRNA transcription was inhibited by RU486, a synthetic anti-progesterone /anti-glucocorticoid. The present study demonstrates for the first time that steroids are able to regulate laminin gene expression in mouse uterine tissues, indicating that steroid-regulated laminin gene expression is involved in uterine growth and probably differentiation.

• The Research Journal of the Costume Culture
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• v.26 no.3
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• pp.313-326
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• 2018

Over the past few years, companies have started moving into specific niches in plus-size fashion. The purpose of this study was to verify the marketability of young plus-size clothes in the USA. Data were collected from female consumers aged from 20 to 39 who have experience of purchasing plus-size items. A total of 282 responses were used for statistical analysis. The research result is as follows. First, the obesity stress is affected more by the subjective obesity level than by the objective obesity level and by how people recognize their body types. Second, from an analysis of the factors affecting the shopping orientation of plus-size consumers, style consciousness, pursuing reasonable, emphasizing comfort, and body consciousness are found to be important factors. Third, even if responders are aware of their exact body size, they actively look for the correct size. Fourth, fit evaluation of plus-size products is based on the factors of size fit and movement fit. The respondents were unsatisfied with chest and arm measurements, which deviate widely by body type for tops. Fifth, the overall dissatisfaction with the plus-size market is attributed to the fact that the product assortment range from which to select styles is narrow, and trend reflection is low. Sixth, the respondents tended to avoid fabrics that make their body type more obvious, textures that give the impression of a larger body size, or stiff textures. These results show that the psychological and physical characteristics of obese consumers should be considered to develop products for the young plus-size market.

• Journal of the Computational Structural Engineering Institute of Korea
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• v.13 no.4
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• pp.437-448
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• 2000

In this study, a numerical analysis method for soil-pile interaction in frequency domain problem is presented. The total soil-pile interaction system is divided into two parts so called near field and far field. In the near field, beam elements are used lot a pile and plain strain finite elements for soil. In the far field, dynamic fundamental solution for multi-layered half planes based on boundary element formulation is adopted lot soil. These two fields are coupled using FE-BE coupling technique. In order to verify the proposed soil-pile interaction analysis, the dynamic responses of pile on multi-layered half planes are simulated and the results are compared with the experimental results. Also, various numerical analyses of piles considering different conditions of soil-pile interaction system are performed to examine the dynamic behavior of the system. It has been found that the developed method which satisfies the radiation conditions of multi-layered half planes can be applied to various structure systems effectively in frequency domain.

• Journal of Sasang Constitutional Medicine
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• v.21 no.2
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• pp.79-86
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• 2009

1. Objective : This study aimed to know the concordance coefficient and diagnostic trend of 6 Sasang constitution diagnosis factors among experts, which are important to diagnose Sasang constitution. 2. Methods : We suggested each 100 cases containing body shape, face, temperament, physiological and pathological symptom and constitutional drug response to 2 groups experts, and researched expert opinions. We analyzed concordance coefficient with Kendall's coefficient of concordance W. 3. Results : 1) Experts agreed with 167(82.5%) diagnosis results of cases, but there were 33 cases(17.5%), with which even one expert disagreed 2) The concordance of priority order of Sasang constitutional factors was significantly associated within expert. 3) Experts put the priority concordance to drug response and Face, body shape, voice and Pathological and physiological symptoms in order. 4) In case by case, concordance coefficient was 47(55.9%) in group 1, 9(10.8%) in group 2, 56 (33.5%) in total. 4. Conclusions : Experts made much account of drug responses and faces in diagnosing Sasang constitution. but there were different opinions in concordance coefficient. So Sasang Constitution Diagnosis Guideline is necessary to integrate experts opinions.