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Amino Acid Imbalance-Biochemical Mechanism and Nutritional Aspects

  • Park, Byung-Chul
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.9
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    • pp.1361-1368
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    • 2006
  • Amino acid imbalances refer to the deleterious effects that occur when a second-limiting amino acid or mixture of amino acid lacking a particular limiting amino acid is supplemented in diets marginal in one or more indispensable amino acids. In spite of variation in the conditions that have been used to induce amino acid imbalances, such as protein level in the diet, the extent of difference in total nitrogen content between basal and imbalanced diets, and kinds of amino acids used as imbalancing agents, the conspicuous common features of amino acid imbalances have been a decreased concentration of the limiting amino acid in blood, depression of feed intake and weight gain, and increased dietary content of the limiting amino acid needed to correct the imbalances. There is strong evidence that a decrease in the concentration of a limiting amino acid detected in the anterior prepyriform cortex of the brain is followed by behavioral effects, especially a decrease in feed intake. This might be due to the competition between the limiting amino acid and the amino acids in the imbalancing mixture for transport from blood into brain. One of the biochemical responses of animals fed amino acid imbalanced diets is a rapid decrease in the concentration of the limiting amino acid, which are due in part to an increase in catabolism of the limiting amino acid by the increased activities of enzymes involved in the catabolism of the amino acid. Practically, specific amino acid imbalances could be induced in swine and poultry diets that have been supplemented with lysine, methionine, tryptophan when threonine, isoleucine, valine, etc. are potentially third- or fourth-limiting in diets. In these cases supplementation of the limiting amino acid could be beneficial in preventing the decrease of feed intake that could otherwise occur as a result of amino acid imbalance.

A Study on Faculty's Perceptions on Convergence Education in N-University (N-대학의 융합교육에 대한 교수의 인식조사 연구)

  • Jun, Soo Koung;Chang, Ik Jun;Park, Eun Sook
    • Korean Educational Research Journal
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    • v.41 no.2
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    • pp.55-70
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    • 2020
  • The purpose of this study was to investigate the perceptions of faculty as a foundation for establishing a convergence education model at N-University. In September 2019, a survey was conducted using an online survey system, and a total of 80 responses were obtained. SPSS 23 was used for analysis, and a t-test, ANOVA, and multiple regression analysis were performed. First, the female faculty were significantly more positive about linked-major expansion than were the male faculty. Second, assistant faculty were significantly more positive about convergence curriculum establishment than were associate faculty. Third, as a result of the multiple regression analysis, the preference for multimajor expansion was the most significant and positively influencing factor on the convergence curriculum establishment. Universities must provide various incentives to form a consensus among university faculty. The Ministry of Education must support individual universities through the establishment of clearer guidelines and a kind of convergence education support center.

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Seismic performance of high-strength steel framed-tube structures with bolted web-connected replaceable shear links

  • Lian, Ming;Cheng, Qianqian;Guan, Binlin;Zhang, Hao;Su, Mingzhou
    • Steel and Composite Structures
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    • v.37 no.3
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    • pp.323-339
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    • 2020
  • In steel framed-tube structures (SFTSs), the plastic hinges at beam-ends cannot be adequately improved because of the large cross sections of spandrel beams, which results in the lower ductility and energy dissipation capacities of traditional SFTSs. To address this drawback, high-strength steel fabricated SFTSs with bolted web-connected replaceable shear links (HSFTS-SLs) have been proposed. In this system, shear links use conventional steel and are placed in the middle of the deep spandrel beams to act as energy dissipative components. In this study, 2/3-scaled HSFTS-SL specimens were fabricated, and cyclic loading tests were carried out to study the seismic performance of both specimens. The finite element models (FEMs) of the two specimens were established and the numerical results were compared with the test results. The results showed that the specimens had good ductility and energy dissipation capacities due to the reliable deformation capacities. The specimens presented the expected failure modes. Using a shorter shear link can provide a higher load-carrying capacity and initial elastic lateral stiffness but induces lower ductility and energy dissipation capacity in HSFTS-SLs. The performance of the specimens was comparable to that of the original sub-structure specimens after replacing shear links. Additionally, the expected post-earthquake recoverability and resilience of the structures could be achieved by replacing shear links. The acceptable residual interstory drift that allows for easy replacement of the bolted web-connected shear link was 0.23%. The bolted web-connected shear links had reliable hysteretic responses and deformation capacities. The connection rotation had a notable contribution to total link rotation. The results of the numerical analysis run for the proposed FEMs were consistent with the test results. It showed that the proposed FEMs could be used to investigate the seismic performance of the HSFTS-SL.

Effects of Income Level on the Association Between Hypertension and Depression: 2010-2017 Korea National Health and Nutrition Examination Survey

  • Kang, San;Kim, Hyeon Chang
    • Journal of Preventive Medicine and Public Health
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    • v.53 no.6
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    • pp.439-446
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    • 2020
  • Objectives: This study analyzed the associations of hypertension (HTN) with symptoms and diagnosis of depression by income level among Korean adults. Methods: This study was based on the 2010-2017 Korea National Health and Nutrition Examination Survey data; a total of 29 425 adults (aged 20 years or older) were analyzed. HTN was defined as a systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or use of hypertensive medications. Depression symptoms were evaluated based on a questionnaire about depression-related symptoms. A depression diagnosis was defined based on questionnaire responses indicating that a participant had been diagnosed with depression. Household income was divided into higher or lower income ranges based on the median income of the participants. Multiple logistic regression analyses were performed to assess the associations between HTN and depression symptoms/diagnosis in the higher-income and lower-income groups. Results: In the higher-income group, the odds ratio (OR) for the association between HTN and depression symptoms was 1.15 (95% confidence interval [CI], 0.97 to 1.37), and the OR for the association between HTN and depression diagnosis was 1.41 (95% CI, 1.13 to 1.76). In the lower-income group, the OR for the association between HTN and depression symptoms was 1.18 (95% CI, 1.04 to 1.34), whereas the OR for the association between HTN and depression diagnosis was 0.82 (95% CI, 0.70 to 0.97). Conclusions: The associations of HTN with symptoms and diagnosis of depression differed by income level.

Development of an Nursing Assessment Tool for Emergency Patients (응급환자 간호사정 도구개발)

  • Ahn, Mi-Hyun
    • Journal of Korean Academy of Nursing Administration
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    • v.4 no.2
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    • pp.419-437
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    • 1998
  • Nurses use a nursing process. that is a scientific approach method. in order to understand the clients' condition and to solve their problems. Professional nurses have accepted the nursing process as a standard framework for nursing activities, and the first step of the nursing process is nursing assessment. The purpose of this study was to develop a nursing assessment tool for emergency patients. Assessment is a first step in the nursing process, and scientific assessment helps to better understand the patients. Thus the development of an assessment tool for emergency patients will improve of nursing quality and advance to efficacy of emergency room(ER) management. The study involved the development of a conceptual framework, preliminary tool, content validity verification process. and reliability verification process. The conceptual framework was developed through a review of the literature. and preliminary tool was developed from the conceptual framework that based on care flow sheet' developed James A. Haley. The preliminary tool was evaluated for validity and reliability by seven experts, one ER nurse manager, two ER head nurses, two emergency medicine doctors. and two ER charge nurses and by ten nurses with one to five year careers in ER nursing. The results of this study was as follows 1. The conceptual framework which was developed was composed of three parts. They were triage criteria, first assessment and secondary assessment. 2. The preliminary tool which was developed had 31 items based on the conceptual framework. 3. To test expert validity a 4-point scale was used. items which had gained 3-4 points from six persons of the seven experts were selected. All 31 items from the preliminary tool were selected. 4. The reliability test was done by ten nurses educated in the use of the assessment tool. Two pairs of nurses simultaneously assessed the same patients. A total agreement percentile was calculated and result was 87.3% agreement. 5. After the validity and reliability testing. the final emergency patient nursing assessment tool was finalized with 31 items. and a check-list for the responses. This study concludes that the tool which was developed is both valid and reliable will advance quality care for emergency patients. This emergency nursing assessment tool was also found to be an adequate tool for assessment of emergency patients.

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Extending of TAM through Perceived Trust and its Application to Autonomous Driving (지각된 신뢰에 기반한 기술수용모델의 확장과 자율주행에의 적용에 관한 실증연구)

  • Lee, Kangmun;Roh, Taewoo
    • Journal of Digital Convergence
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    • v.16 no.5
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    • pp.115-122
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    • 2018
  • The purpose of this study is to investigate the effect of technology acceptance model (TAM) on behavioral intention in order to grasp the degree of technology acceptance on autonomous driving among the various factors that consumers perceive as unmanned vehicle system becomes commercialized. In addition to the mediating effect of perceived usefulness proposed by the existing TAM, this study proposed the perceived trust (PT) and hypothesized its mediating effect on behavioral intention to use the self-driving. Path anlaysis is adopted to investigate our hypothesis using the structural equation model. The sample used for the analysis was 149 valid data among 160 responses. The effects of total effect, direct effect, and indirect effect were confirmed by hypothesis test on mediating effect. Non-parametric bootstrapping analysis was also performed to confirm the robustness. All the hypotheses were significant and we found a partial indirect effect, which implies that mediation effect of PT on behavioral intention.

Japanese Female Marriage Immigrants' Dietary Life and Health-related Characteristics by Level of Dietary Adaptation after Immigration to Korea (일본인 여성결혼이민자의 식생활적응 정도에 따른 식생활 및 건강 특성)

  • Asano, Kana;Yoon, Jihyun;Ryu, Si-Hyun
    • Journal of the East Asian Society of Dietary Life
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    • v.25 no.5
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    • pp.765-778
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    • 2015
  • The purpose of this study was to investigate Japanese female marriage immigrants' dietary life and health-related characteristics after immigration to Korea. A survey was conducted with Japanese women married to Korean men and having one child or more aged 7 to 18 years old. Data were collected from 243 women during the summer of 2014. A total of 204 questionnaires were analyzed, after excluding 39 questionnaires with a high percentage of incomplete responses (84% analysis rate). Over 85% of respondents were the members of the Unification Church, and over 92% of respondents had stayed in Korea for longer than 10 years. Based on the overall mean score for dietary adaptation level (3.68 out of 5 points), respondents were classified into two groups: low dietary adaptation group (mean score 3.12) and high dietary adaptation group (mean score 4.19). The collected data were compared between the two groups. The high dietary adaptation group reported higher percentages of decreasing consumption in processed food, confectionary, and bread than the low dietary adaptation group after immigration to Korea. A higher percentage of respondents in the high dietary adaptation group perceived their health status as good and reported changes that led to a healthier dietary life after immigration to Korea compared with those in the low dietary adaptation group. In conclusion, Japanese female marriage immigrants well adapted to Korean dietary life tended to eat healthier and perceive health status better compared with those who were not well adapted. The results of this study could be useful for prospecting dietary life and health-related characteristics of immigrant women in the long term after immigration to Korea.

Genetic Variants in Interleukin-2 and Risk of Lymphoma among Children in Korea

  • Song, Nan;Han, So-Hee;Lee, Kyoung-Mu;Choi, Ji-Yeob;Park, Sue-K;Jeon, Su-Jee;Lee, Yun-Hee;Ahn, Hyo-Seop;Shin, Hee-Young;Kang, Hyoung-Jin;Koo, Hong-Hoe;Seo, Jong-Jin;Choi, Ji-Eun;Kang, Dae-Hee
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.2
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    • pp.621-623
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    • 2012
  • To estimate the genetic susceptibility for childhood lymphoma, we conducted an association study for 23 cases and 148 controls. Total 1536 tag single nucleotide polymorphisms (SNPs) were selected in 138 candidate gene regions related to immune responses, apoptosis, the cell cycle, and DNA repair. Twelve SNPs were significantly associated with the risk of lymphoma ($P_{trend}$ <0.05) in six genes ($IL1RN$, $IL2$, $IL12RB1$, $JAK3$, $TNFRSF13B$, and $XRCC3$). The most significant association was seen for $IL2$ variant rs2069762 ($OR_{TG+GG}$ vs. TT=3.43 (1.29-9.11), $P_{trend}$=0.002, min$P$=0.005). These findings suggest that common genetic variants in $IL2$ might play a role in the pathogenesis of childhood lymphoma.

Effects of Restricted Feeding on Performance, Carcass Quality and Hormone Profiles in Finishing Barrows

  • Cho, S.B.;Cho, S.H.;Chang, S.S.;Chung, I.B.;Lim, J.S.;Kil, D.Y.;Kim, Yoo Yong
    • Asian-Australasian Journal of Animal Sciences
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    • v.19 no.11
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    • pp.1643-1648
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    • 2006
  • To investigate the effects of feeding restricted on growth, carcass characteristics and plasma profiles in an attempt for optimum responses, a total of 108 cross-bred finishing barrows [(Landrace${\times}$Yorkshire)${\times}$Duroc]weighing an average of $46.88{\pm}0.52kg$ were assigned in a randomized complete block (RCB) design to one of four treatments with three replicates and nine pigs per pen. Feeding regimens were, 1) ad libitum from 50 kg to market weight (Ad 3/3), 2) restricted feeding from 90 kg to market weight (Ad 2/3), 3) restricted feeding from 70 kg to market weight (Ad 1/3), and 4) restricted feeding from 50 kg to market weight (Ad 0/3). During the experimental period, average daily feed intake (ADFI) was decreased from 2.53 kg (AD 3/3) to 2.09 kg (AD 0/3) with increasing restricted feeding duration of (p<0.05). Average daily gain (ADG) of AD 3/3 (0.79 kg) was significantly higher (p<0.05) than those of AD 1/3 (0.74 kg) or AD 0/3 (0.72 kg). Feed efficiency was not influenced by restriction regimens. Blood IGF-I concentrations were increased from 74.14 to 134.25 (167.36-115.66) ng/ml as body weight increased. Blood leptin concentrations were affected by feed intake level and coincided with blood IGF-I concentrations. Most of carcass characteristics were not significantly affected by restricted feeding, however cooking losses in AD 1/3 and Ad 0/3 treatment diet were higher than those in Ad 3/3 and Ad 2/3. In addition, there was a trend that backfat thickness was lowered in proportional to decreasing feed intake (p>0.05). In conclusion, restricted feeding improved feed efficiency after 50 kg body weight without deteriorating the pork quality of barrows.

The Effects of Soil Improvements on Growth and Tissue Nutrient Concentrations of Fraxinus rhynchophylla and Pinus densiflora Seedlings in a Nursery (토양개량제 처리가 물푸레나무와 소나무 묘목의 생장과 양분농도에 미치는 영향)

  • Park, Byung Bae;Byun, Jae Kyung;Cho, Min Seok;Han, Si Ho;Jung, Mun Ho;Kim, Se Bin;Bae, Kikang
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.19 no.2
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    • pp.41-54
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    • 2016
  • The production of high quality seedlings is a very important phase in silvicultural systems for successful reforestation or restoration. The purpose of this study was to measure both growth performances and nutrient responses of Fraxinus rhynchophylla and Pinus densiflora seedlings, which are commercially planted in Korea, according to soil improvement treatments. We applied 8 types of soil improvements: control with no treatment, compost B and compost Y as organic materials, vermiculite, perlite, two level of zeolite, and mix of vermiculite, perlite, and zeolite as inorganic materials in a permanent national nursery. Only compost B treatment significantly increased soil pH, organic matter, total nitrogen, available phosphorus, exchangeable potassium and calcium at the 0-10 cm soil depth. The growth of F. rhynchophylla and P. densiflora was the highest at the compost B treatment and the lowest at the vermiculate treatment. Compost B treatment allocated more carbon to aboveground than belowground by 39%, especially to foliage. On the vector diagnosis, there was 'shortage' on compost B treatment because of all increases of N contents, N concentrations, and growth and 'over accumulation' on vermiculite treatment because of more N uptake compared with dry weight increase. This study suggested optimal use of soil improvements is very important to improve soil quality in a permanently used nursery.