• The Korean journal of internal medicine
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• v.39 no.4
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• pp.659-667
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• 2024

Background/Aims: Sensitization to staphylococcal superantigens (SAgs) could contribute to asthma severity. However, its relevance with eosinophilic phenotype has not yet been clarified. This study aimed to investigate associations between serum specific IgE levels to SAg and eosinophilic airway inflammation in adult asthmatics. Methods: The serum specific IgE levels to 3 SAgs, including staphylococcal enterotoxin A (SEA) and B (SEB), and toxic shock syndrome toxin-1 (TSST-1) were measured by ImmunoCAP in 230 adult asthmatic patients and 50 healthy controls (HCs). Clinical characteristics and laboratory parameters, including serum total/free IgE, and 2 eosinophil-activation markers, eosinophil cationic protein (ECP), and eosinophil-derived neurotoxin (EDN), were analyzed according to blood eosinophil counts (BEC; 150 cells/µL) and serum specific IgE levels to 3 SAgs (0.35 kU/L). Results: Asthmatic patients showed higher serum specific IgE levels to 3 SAgs than HCs (p < 0.05 for all). The serum total/free IgE levels were significantly higher in asthmatics with positive IgE responses to 3 SAgs than those without (p < 0.05 for all). There were no significant differences in clinical parameters including age, asthma severity, comorbidities, or smoking according to IgE responses to 3 SAgs. Patients with positive IgE responses to SEB (not to SEA/TSST-1) had higher serum specific IgE levels to house dust mites and ECP/EDN as well as higher BEC with positive correlations between serum SEB-specific IgE levels and BEC/ECP/EDN (p < 0.05 for all). Conclusions: These findings suggest that serum SEB-specific IgE levels could contribute to eosinophil activation as well as IgE production in adult asthma.

• Journal of Korean Society of Forest Science
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• v.90 no.1
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• pp.133-138
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• 2001

Increased base cation loss and Al mobilization, a consequence of soil acid neutralization responses, are common in air polluted areas showing forest decline. The prediction models of acid neutralization responses were developed by using indicators of soil acidification level(pH, and base saturation) in order to assess the forest soil sensitivity to acidification. The soil acidification level was greatest in Namsan followed by Kanghwa, Ulsan, and Hongcheon, being contrary to regional total $ANC_H$ pattern through soil columns leached with additional acid ($16.7mmol_c\;H^+/kg$), Both base exchange and Al dissolution were main acid neutralization processes in all study regions. There were low base exchange and high Al dissolution in the regions of the low total $ANC_H$. The $ANC_M$ by sulfate adsorption was greatest in Hongcheon compared with other regions even though the AN rate was very low as 6.4%. Coefficients of adjusted determination of simple and multiple regression models between soil acidification level indicators and the acid neutralization responses were more than 0.52(p<0.04) and 0.89(p<0.01), respectively. The result suggests that soil pH and base saturation are available indicators for predicting the acid neutralization responses. These prediction models could be used as an useful method to measure forest soil sensitivity to acidification.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1998.11a
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• pp.147-147
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• 1998

The present study was designed to examine the effect of total ginseng saponin on CA secretion evoked by activation of nicotinic receptors from the isolated perfused rat adrenal glands. Total ginseng saponin given (100 $\mu\textrm{g}$/20 min) into an adrenal vein did fail to produce alteration of spontaneous CA release from the rat adrenal medulla. Acetylcholine (5.32 mM)- and DMPP (100 uM, a selective ncotinic receptor agonist)-evoked CA secretory responses were reduced markedly by the pretreatment with the total ginseng saponin at a rate of 100 $\mu\textrm{g}$/6.2 $m\ell$/20 min, respectively.

• Journal of the Korean Society of Clothing and Textiles
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• v.16 no.4 s.44
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• pp.405-416
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• 1992

This study was performed to investigate correlation between total body weight loss and local sweat rate and to find out any possible method that can estimate total body weight loss judging from local sweat rate. Twelve adult females were kept at 44 $\pm1^{\circ}C$, 50 ${\pm}5\%$ R.H. (1) Physiological responses such as total body weight loss, local sweat rate, rectal temperature, skin temperature, blood pressure and pulse, (2) micro climate inside garment and (3) subjective sensation were examined. Two types of garment such as long-sleeves with long pants (Type I) and half·sleeves with short pants (Type II) were used to observe the effect of garment types on sweating response. Both clothing weight was equal (132$\pm$3 g/$m^{2}$). The results were as follows: 1. Regardless of the different types, total body weight loss was more interrelated with the sweat rate on forehead than any other parts of the body. Except the forehead, different parts of body with different types of garment influenced on body weight loss quite differently. 2. Total body weight loss was more interrelated with the weight gain of garment than the local sweat rate. 3. Under the environment of 44$\pm1^{\circ}C,\;50{\pm}5\%$R.H., body weight loss during 1 hour of subject clothed and silted was 275.2 g/hr and weight loss per body surface area was 178.9 g/$m^{2}/hr$ Garment types have no influences on total body weight loss. 4. Local sweat rate (mg/7.07 $cm^{2}/hr$) was 208.0,191.0, 133.0, 115.0,81 0, 75.1 and 66.3 on scruff, breast, forehead, forearm, thigh, upper arm, leg respectively No evidence has been found that garment types influenced on local sweat rate (p<0.1). 5. No interrelationships between rectal temperature and total body weight loss, local skin temperature and total body weight loss, and local skin temperature and local sweat rate were found. From this study, some possible method that we can estimate total body' weight loss judging from weight loss of garment. But considering the fact that clothing design factor, the physical characteristics of fabric and environmental factor such as humidity and wind velocity should be concerned in weight loss of garment, it should be studied further whether the total body weight loss can be estimated properly from the weight loss of garment. This experiment suggest that different parts of body with different types of garment can influence on body weight loss quite differently. Therefore, in order to get more precise results, more studies under the diversity of garment types should be done in the near future.

• Journal of The Korean Association For Science Education
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• v.36 no.3
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• pp.389-397
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• 2016

This study aims to test the efficacy of English-based automated computer scoring models and machine translation to score Korean college students' written responses on natural selection concept items. To this end, I collected 128 pre-service biology teachers' written responses on four-item instrument (total 512 written responses). The machine translation software (i.e., Google Translate) translated both original responses and spell-corrected responses. The presence/absence of five scientific ideas and three $na{\ddot{i}}ve$ ideas in both translated responses were judged by the automated computer scoring models (i.e., EvoGrader). The computer-scored results (4096 predictions) were compared with expert-scored results. The results illustrated that no significant differences in both average scores and statistical results using average scores was found between the computer-scored result and experts-scored result. The Pearson correlation coefficients of composite scores for each student between computer scoring and experts scoring were 0.848 for scientific ideas and 0.776 for $na{\ddot{i}}ve$ ideas. The inter-rater reliability indices (Cohen kappa) between computer scoring and experts scoring for linguistically simple concepts (e.g., variation, competition, and limited resources) were over 0.8. These findings reveal that the English-based automated computer scoring models and machine translation can be a promising method in scoring Korean college students' written responses on natural selection concept items.

• Korean Journal of Human Ecology
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• v.21 no.2
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• pp.389-405
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• 2012

The purposes of this study were to investigate students' perception on importance and performance of service quality of university foodservice, and to examine Importance-Performance Analysis(IPA) of foodservice quality for male and female students. A total of 500 university students in Daejeon were surveyed and 432 responses were returned. Excluding responses with significant missing data, 412 responses were used for data analysis. In terms of importance of service quality attributes, 'sanitation(4.74)' category received the highest score, followed by 'food(4.36)', 'service(4.22)', 'convenience(4.01)', 'menu(3.90)' and 'atmosphere(3.73)'. In terms of performance, the highest service quality attribute was associated with 'convenience(3.30)', followed by 'service(3.06)', 'sanitation(2.95)', 'food(2.88)', 'atmosphere(2.79)' and 'menu(2.68)'. As the results of IPA, 'staff's kindness', 'overall quality of service', 'taste of the food', 'freshness of the food', 'overall quality of the food', and 'cleanliness of the facility' fell into the Quadrant IV(Focus here) for female students. On the other hand, male students' IPA grid illustrated that 'taste of the food', 'freshness of the food', 'nutrition of the food', 'sanitation of the food', and 'sanitation of the utensils' fell into Quadrant IV(Focus here).

• Journal of Korea Multimedia Society
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• v.23 no.7
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• pp.862-869
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• 2020

This study attempted to analyze human brain responses toward visual content through EEG signals and intended to measure brain wave reactions of different age groups to determine the sexuality level of the media. The experimental stimuli consist of three different video footage (rated ages 12, 15, and 18) to analyze how subjects react in situations where they actually watch sexual content. For measuring and analyzing brain wave reactions, EEG equipment records alpha, beta, and gamma wave responses of the subjects' left and right frontal lobes, temporal lobes, and occipital lobes. The subjects of this study were 28 total and they are divided into two groups. The experiment configures a sexual content classification scale with age or gender as a discriminating variable and brain region-specific response frequencies (left/right, frontal/temporal/occipital, alpha/beta/gamma waves) as independent variables. The experimental results showed the possibility of distinguishing gender and age differences. The apparent differences in brain wave response areas and bands among high school girls, high school boys, and college students are found. Using these brain wave response data, this study explored the potential of developing algorithm for measurement of age-specific responses to sexual content and apply it as a film rating.

• Journal of Korean Academy of Fundamentals of Nursing
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• v.14 no.4
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• pp.446-456
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• 2007

Purpose: The purpose of study was to identify violence episodes by patients and/or their guardians and responses from emergency room nurses. Method: A convenient sample of 172 emergency nurses was selected from general hospitals with more than 200 beds. A survey design was used and data were collected from October 2 to October 11, 2006. using self-report questionnaires which were developed by the authors. Descriptive statistics, with the SPSS PC program were used to analyze the data. Results: The majority of nurses(97.1%) had experienced violence by patients or their guardians in the previous month. Violence offenders who were drunk comprised 68.6% of total offenders. Causes of violence were delays in examination and treatment(59.9%). The major coping behavior in dealing with violence episodes was ignoring(40.1%). Responses to violence experienced by emergency nurses were rated as 2.39. Response to violence according to general characteristics of the nurses showed no statistically significant differences. Conclusion: Considering the high prevalence of violence experienced by emergency nurses, hospitals must develop and manage preventive education programs and policy.

• Korean Journal of Poultry Science
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• v.19 no.1
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• pp.17-25
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• 1992

The efficacy of B$_1$l live vaccine which is used successfully in chicken was examined against Newcastle disease in quails. A total of 480 male quails were divided into 4 groups, of which 3 groups were vaccinated via drinking water, eye instillation and spraying method and the remaining was employed as a nonvaccinated control group. At 3 weeks after the first vaccination a part of quails in each group was revaccinated. Efficacy of the vaccine was evaluated by the antibody responses and the protection rates after challenge with a virulent NDV. Vaccination of quails with $B_1$ NDV at 10 days of age resulted in beneficial effect compared to nonvaccinated group regardness of vaccination methods adopted although general protection rates were considerably low. Twice vaccination gave higher protection than once vaccination. Hemagglutination inhibition antibody responeses were significantly higher in groups of quails vaccinated by spray and eye instillation method than by drinking water administration. Antibody responses were marked at 2 weeks onward and until 5 to 7 weeks after vaccination. Antibody responses were rapid and marked after second vaccination. However, antibody level did not last longer than 5 to 7 weeks postvaccination. Vaccine caused no adverse effect on quails in terms of growth'rate, body temperature or clinical signs.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.8
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• pp.1145-1149
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• 2004

Immunomodulatory feed additives might offer alternatives to antimicrobial growth promoters in poultry production. This experiment was carried out to test the effect of $\beta$-glucan supplementation on the growth performance and immune response in broilers. Total of 160 day-old broilers were randomly assigned to 4 treatment groups fed corn-soybean diets containing 0, 0.012, 0.025 or 0.05% of $\beta$-glucan supplement in a 6 week feeding experiment. Growth performance, antibody titer against New Castle vaccine, lymphocyte blastogensis, and peritoneal macrophage chemotaxis activity of broilers were evaluated. Results showed that there were no significant differences in weight gain and feed efficiency among the treatments, and no differences in antibody titer was observed. Supplementation of $\beta$-glucan did not elevate the lymphocyte blastogensis among treatments, following stimulation with different mitogens. However, supplementation with 0.025 and 0.05% $\beta$-glucan enhanced the macrophage chemotaxis activity of broilers. These results suggest that $\beta$-glucan may enhance some cell-mediated immune responses of chickens by modulate macrophages ability.