• Title/Summary/Keyword: tortuosity

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A sporadic case of Loeys-Dietz syndrome type I with two novel mutations of the TGFBR2 gene

  • Ha, Jung-Sook;Kim, Yeo-Hyang
    • Clinical and Experimental Pediatrics
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    • v.54 no.6
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    • pp.272-275
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    • 2011
  • A recently recognized connective tissue disorder, Loeys-Dietz syndrome (LDS) is a genetic aortic aneurysm syndrome caused by mutations in the transforming growth factor-receptor type I or II gene (TGFBR1 or TGFBR2). They have distinctive phenotypic abnormalities including widely spaced eyes (hypertelorism), bifid uvula or cleft palate, and arterial tortuosity with aortic aneurysm or dissection throughout the arterial tree. LDS is characterized by aggressive and rapid progression of aortic aneurysm. Therefore, the patients with distinct phenotype, marked aortic dilatation and aneurysm at early age should be suspected to be affected by LDS and rapid TGFBR gene analysis should be done. We report one child diagnosed as LDS due to typical phenotypes and two novel missense mutations of the TGFBR2 gene (c.1526G>T and c.1528A>T).

A Study on the Effect of Acoustic Properties on the Absorption Characteristics of Polyester Fiber Materials (폴리에스터 흡음재 흡음특성에의 음향 물성치 영향평가 연구)

  • Park, Hern-Jin;Jeong, Myong-Guk;Shim, Sung-Young;Lee, Jun
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2003.11a
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    • pp.885-891
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    • 2003
  • Effects of each acoustic property on absorption characteristics of polyester fiber materials has been studied in this paper. It would be impossible for us to measure effects of each acoustic property by experimental method since we cannot make sound-absorbing materials in which only one of the properties is changed. We have adopted a numerical prediction method to carry out parameter studies for each acoustic property. And to get a general behavior of acoustic performance of the materials, the numerical simulation has been repeated to several cases of different bulk density. Finally we have obtained frequency-dependent control factors in the absorption performance which gives us design capability of acoustic absorbing materials.

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INVESTIGATION OF THE MEANDER PLANFORM DEVELOPMENT IN A LABORATORY CHANNEL

  • Yilmaz, L.;Singh, Vijay P.;Mishra, S.K.;Adrian, D.D.;Sansalone, J.J.
    • Water Engineering Research
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    • v.3 no.3
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    • pp.177-193
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    • 2002
  • Experiments were conducted in an initially straight laboratory alluvial channel to investigate channel meandering characteristics. The experimental observations revealed an empirical relation between three types of tortuosity ratios used for describing meandering characteristics. Furthermore, the Strauhal number was found to be higher for bed material with greater resistance to erosion than with lower resistance to erosion. The meandering characteristics were also investigated using the concept of buckling employed in solid mechanics and the concept of siphoning of fluid mechanics. The buckling of flow, attributable to the flow nonuniformity across the channel cross-section, was found to follow the same pattern as did meandering observed experimentally. The processes of expansion of meanders and cut-off can be explained using the concept of siphoning. The results of expanding meander planforms observed in four experimental tests supported the viability of these concepts.

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Diffusion Controlled Alkylation of Aromatic Compounds in Cation-Exchanged ZSM-5 Zeolites

  • Chon, Hak-Ze;Lee, Kyung-Yul;Park, Dong-Ho;Ahn, Byoung-Joon
    • Bulletin of the Korean Chemical Society
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    • v.12 no.6
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    • pp.625-628
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    • 1991
  • Using uniform flat plate-like samples of ZSM-5 zeolites, diffusion coefficients were measured volumetrically for the diffusion of xylene, ethyltoluene and diethylbenzene by direct measurement of sorption rate. Toluene disproportionation over H(100)-, K(72)-and Cs(82)-ZSM-5 at 773 K and toluene methylation, toluene ethylation and ethylbenzene ethylation over Cs(75)-ZSM-5 at 623 K were carried out. The selective formation of para xylene during the toluene disproportionation, presumably due to the increased tortuosity over Cs-ZSM-5, could be explained by smaller diffusion coefficient in Cs-ZSM-5 than in K-and H-ZSM-5. The para selectivity increased in the order; toluene methylation < toluene ethylation < ethylbenzene ethylation. As the chain length of the alkyl substituent in dialkylbenzenes is increased, the para selectivity of the products was improved. It may be attributed to the differences in the ratios of diffusion coefficient of para products to that of ortho ones. Diffusion coefficient of m-xylene was about 1 order of magnitude smaller than that of o-xylene.

Assessment of Carotid Geometry by Using the Contrast-enhanced MR Angiography (조영증강 MR 혈관 조영술을 이용한 경동맥 기하학의 평가)

  • Lee, Chung-Min;Ryu, Chang-Woo;Kim, Keun-Woo
    • Investigative Magnetic Resonance Imaging
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    • v.14 no.1
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    • pp.47-55
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    • 2010
  • Purpose : To evaluate the geometry of carotid artery by assessing the images of contrast-enhanced MR angiography (CE-MRA) and interrelationships between the geometry of carotid artery and clinical factors. Materials and Methods : 216 consecutive patients who performed supraaortic CE-MRA with fast spoiled gradient-echo imaging were included. Their medical records were reviewed for variable information including risk factors predictive of generalized atherosclerotic disease (age, hypertension (HTN), diabetes mellitus, hyperlipidema, and smoking), sex, body weight, height, and body mass index (BMI). We reviewed the CE-MRA with carotid origin (3 types), carotid artery tortuosity, angle of internal carotid artery bifurcation, the type of aortic arch branching, and the presence of the coiling of carotid artery. Results : Multinomial logistic regression analysis showed that significantly contributed clinical backgrounds for carotid origin were the age and the BMI. With an increase of age at 1, the probability that the type of carotid origin become from type 1 to type 2 was 0.9 times (p=0.004) in right carotid artery (RCA), 0.9 times (p = 0.031) in left carotid artery (LCA), 0.9 times that are likely to be type3 from type 2 (p<0.001) in RCA and 0.9 times in LCA (p=0.009). Increase in BMI at 1 increased odds of becoming type 2 as 1.1 times (p = 0.067) in RCA, 1.1 times (p=0.009) in LCA and increased chance of becoming type 3 as 1.2 times (p = 0.001) in RCA, 1.2 times (p=0.003) in LCA. Mean value of right and left carotid tortuosity were $240.9{\pm}69.0^{\circ}$and $154.4{\pm}55.0^{\circ}$, respectively. Conclusion : The BMI, age, sex and presence of HTN affects the geometry of carotid arteries, the site of origin and tortuosity of carotid artery specifically.

Morphometrical characteristics of River Meandering (하천 사행의 계량형태학적 특성)

  • 이재우;이원환
    • Water for future
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    • v.14 no.1
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    • pp.39-49
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    • 1981
  • The purpose of this study is to examine the meander charactericstics for the rivers in Korea..In this study, the new characteristics factors of meander are proposed, and the relationships among the factors proposed in this study and the existing factors are derived. An attempt is made to find considerable relation among meander characteristics, but width and meander belt did not show any defined trend and considerable scatter of points was observed. Relationships among the meander length, belt and flowrate, etc., which are factors of meander characteristics, are analyzed the 67 rivers above 30km in length. Channel shape factor which is the ratio of the length from the starting point to the end to the channel lenght, tortuosity which is the ratio of the curved channel length against the channel length are suggested for a new characteristics factor of meander. They are well correlated with channel length, Horton's shape facotr and meander gradient, consequently have to be important measures of river meander. The result of the detailed comparison and the analysis of degree of sinuosity, velocity and water surface slop are brought light on the fact show that the curved reach is morestable than the straight one. The ratio of the meander length to the meander belt and its accumulative frequency showed excellent correlationship when plotted on the semi-log paper. The results of regression analysis of meander belt and meander length show linear for the South Han river branches and power curve for the Geum river and the Nakdong river branches.

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Preparation and Gas Barrier Properties of Chitosan/Clay Nanocomposite Film (Chitosan/Clay 나노복합재료 필름의 제조와 기체투과 특성)

  • Nam Sang Yong;Park Ji Soon;Rhim Ji Won;Park Byung Gil;Kong Sung-Ho
    • Membrane Journal
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    • v.15 no.3
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    • pp.247-254
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    • 2005
  • Chitosan film has potential applications in agriculture, food, and pharmacy. However, films made only from chitosan lack gas barrier and have poor mechanical properties. For enhanced gas barrier and mechanical properties, chitosan/clay nanocomposites have been prepared with montmorillonite (MMT) which is a layered structure of clays and chitosan. The cationic biopolymer, chitosan is intercalated into $Na^+-montmorillonite$ through cationic exchange and hydrogen bonding process. Diluted acetic acid is used as solvent f3r dissolving and dispersing chitosan. Chitosan was intercalated or exfoliated in MMT and it was confirmed by X-ray diffraction method. D-spacing of the characteristic peak from MMT plate in chitosan/clay nanocomposites was moved and diminished. The thermal stability and the mechanical properties of the nanocomposites are measured by TGA and Universal Testing Machine. Gas permeability through the chitosan/clay nanocomposites films decreased due to increased tortuosity made by intercalation of clay in chitosan.

Modeling the electric transport of HCl and H3PO4 mixture through anion-exchange membranes

  • Koter, Stanislaw;Kultys, Monika;Gilewicz-Lukasik, Barbara
    • Membrane and Water Treatment
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    • v.2 no.3
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    • pp.187-205
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    • 2011
  • The electric transport of the mixture of hydrochloric and phosphoric acids through strong base (Neosepta ACM) and weak base (Selemion AAV) anion-exchange membranes was investigated. The instantaneous efficiency of HCl removal from the cathode solution, $CE_{Cl}$, with and without $H_3PO_4$ was determined. It was found that $CE_{Cl}$ was 0.8-0.9 if the number of moles of elementary charge passed through the system, $n_F$, did not exceed ca. 80% of the initial number of HCl moles in the cathode solution, $n_{Cl,ca,0}$. The retention efficiency of $H_3PO_4$ in that range was close to one. The transport of acid mixtures was satisfactorily described by a model based on the extended Nernst-Planck and Donnan equations for $n_F$ not exceeding $n_{Cl,ca,0}$. Among the tested model parameters, most important were: concentration of fixed charges, the porosity-tortuosity coefficient, and the partition coefficient of an undissociated form of $H_3PO_4$. For the both membranes, the obtained optimal values of fixed charge concentration, $\bar{c}_m$, were up to 40% lower than the literature values of $\bar{c}_m$ obtained from the equilibrium measurements. Regarding the $H_3PO_4$ equilibria, it was sufficient to consider $H_3PO_4$ as a monoprotic acid.

Opportunity Rover's image analysis: Microbialites on Mars?

  • Bianciardi, Giorgio;Rizzo, Vincenzo;Cantasano, Nicola
    • International Journal of Aeronautical and Space Sciences
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    • v.15 no.4
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    • pp.419-433
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    • 2014
  • The Mars Exploration Rover Opportunity investigated plains at Meridiani Planum, where laminated sedimentary rocks are present. The Opportunity rover's Athena morphological investigation showed microstructures organized in intertwined filaments of microspherules: a texture we have also found on samples of terrestrial (biogenic) stromatolites and other microbialites. We performed a quantitative image analysis to compare images (n=45) of microbialites with the images (n=30) photographed by the rover (corresponding, approximately, to 25,000/15,000 microstructures). Contours were extracted and morphometric indexes were obtained: geometric and algorithmic complexities, entropy, tortuosity, minimum and maximum diameters. Terrestrial and Martian textures present a multifractal aspect. Mean values and confidence intervals from the Martian images overlapped perfectly with those from the terrestrial samples. The probability of this occurring by chance is $1/2^8$, less than p<0.004. Terrestrial abiogenic pseudostromatolites showed a simple fractal structure and different morphometric values from those of the terrestrial biogenic stromatolite images or Martian images with a less ordered texture (p<0.001). Our work shows the presumptive evidence of microbialites in the Martian outcroppings: i.e., the presence of unicellular life on the ancient Mars.

Post-buckling analysis of aorta artery under axial compression loads

  • Akbas, Seref Doguscan;Mercan, Kadir;Civalek, Omer
    • Advances in nano research
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    • v.8 no.3
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    • pp.255-264
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    • 2020
  • Buckling and post-buckling cases are often occurred in aorta artery because it affected by higher pressure. Also, its stability has a vital importance to humans and animals. The loss of stability in arteries may lead to arterial tortuosity and kinking. In this paper, post-buckling analysis of aorta artery is investigated under axial compression loads on the basis of Euler-Bernoulli beam theory by using finite element method. It is known that post-buckling problems are geometrically nonlinear problems. In the geometrically nonlinear model, the Von Karman nonlinear kinematic relationship is employed. Two types of support conditions for the aorta artery are considered. The considered non-linear problem is solved by using incremental displacement-based finite element method in conjunction with Newton-Raphson iteration method. The aorta artery is modeled as a cylindrical tube with different average diameters. In the numerical results, the effects of the geometry parameters of aorta artery on the post-buckling case are investigated in detail. Nonlinear deflections and critical buckling loads are obtained and discussed on the post-buckling case.