• 대한치과의사협회지
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• 제54권8호
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• pp.592-603
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• 2016

Pathologic tooth migration (PTM) caused by periodontal disease is a relatively common disease with a prevalance rate of 30~55%. It is one of the reasons for periodontal treatment of patients. PTM occurs when various factors related to the position of the tooth are altered and clinical features of PTM include facial flaring, diastema, proximal tilting, rotation, and extrusion of teeth. The purpose of this study was to assess the treatment of teeth of hopeless prognosis through the practice of modified intentional replantation on pathologic migrated tooth. This study presents cases using modified intentional replantation for the treatment of pathologic tooth migration caused by severe periodontitis. Modified intentional replantation is a technique that prepares extraction socket by using an implant drill. Based on 3 cases performed with modified intentional replantation, an improvement of clinical periodontal indicators such as probing pocket depth, bleeding on probing, tooth mobility, and pathologic teeth migration was observed after surgery. Also, the patients were satisfied with the functional and esthetic improvement.

• Journal of Periodontal and Implant Science
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• 제41권1호
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• pp.44-50
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• 2011

Purpose: Pathologic tooth migration (PTM) is a tooth displacement which is derived from imbalance of tooth retention force and is dominantly found out in maxillary anterior area. PTM in maxillary anterior area was tried to corrected with periodontal treatment and a clear aligner in this study and the result was evaluated clinically and radiographically. Methods: For the treatment of a patient with chronic periodontal disease accompanied by maxillary anterior pathologic tooth migration, clear aligner was applied to move teeth after a series of case-related periodontal therapy. Clinically, probing depth, gingival recession, clinical attachment level and mobility were measured pre- and post-treatment, and radiographic examination was performed as well. Results: Clinically, we found the decrease of the probing depth, gingival recession, clinical attachment level and mobility. And we could also acknowledge the reduction of vertical and horizontal dimension on infrabony defect radiographically. However, it is still controversial if there was an actual bone filling. Conclusions: Clear aligner is an effective appliance to move teeth since it costs little in terms of expense and time. In addition, it wraps whole crowns, providing advantages to deal with crowding, spacing, and size of arch. In short, clear aligner could be a useful treatment option for PTM patient, since it provides decreased probing depth, gingival recession, clinical attachment level, mobility and esthetical restoration.

• Journal of Periodontal and Implant Science
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• 제38권sup2호
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• pp.405-412
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• 2008

Purpose: Pathologic tooth migration (PTM) commonly occurs in the anterior region and is associated with periodontal disease. The treatment of PTM of anterior teeth can be complex and time consuming, and a multidisciplinary approach is often required. Materials and Methods: The patient was a 38-year-old woman with a chief complaint of saving and realigning her elongated maxillary left central incisor. This paper describes the successful combined periodontal regenerative (guided tissue regeneration) and prosthetic treatment and a 2-year follow-up of maxillary central incisor with pathologic tooth migration, deep intrabony defect, and poor prognosis. Results: The right maxillary central incisor was restored by laminate veneer and the left by all-ceramic crown. The patient had no pain and discomfort and was satisfied with the outcomes of her treatment for 2 years. She has maintained her recall program at the Department of Periodontology at 3 months interval. Conclusion: The key step in the successful treatment of PTM in anterior region is to obtain a high level of cooperation from the patient. Maintenance of the treatment result of PTM is dependent on the continuous preservation of periodontal health.

• 구강회복응용과학지
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• 제38권1호
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• pp.26-33
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• 2022

전치부 치간 사이 공간은 치주 환자에게 흔히 발생되는 병적 치아 이동(PTM, pathological tooth migration)과 함께 자주 관찰된다. PTM에는 다양한 교합적 요인들이 기여하는데 특히 상악 전치부에서는 과도한 교합력이 있을 때 위치 문제로 인한 불리함 때문에 치간 이개가 쉽게 발생한다. 치주 지지 조직이 소실된 치아는 의도적인 연결 고정(splinting)을 통해 지지 면적을 확장하면 안정성이 증가될 수 있다. 또한 고정성 보철물로 수복 시에는 불리한 교합을 유리한 형태로 바꿀 수 있다. 임시보철물을 통해 안정적 교합을 확보 후 이것을 최종보철물로 옮기는 일은 CAD-CAM을 통하여 가능하다. 본 증례에서는 치간 접촉이 상실된 상악 전치부에서 정확한 진단과 치료를 통해 장기적으로 안정적인 결과를 보여 소개하고자 한다.

• 대한치과의사협회지
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• 제55권6호
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• pp.388-399
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• 2017

Generalized aggressive periodontitis cause intrabony pocket, loss of teeth, and severe alveolar bone defect. As a result, pathologic tooth migration occurs and esthetic problem happens according to this, especially on the anterior teeth of maxilla. The purpose of this study was to assess the multidisciplinary treatment including periodontics, orthodontics and prosthetics of a patient caused by generalized aggressive periodontitis. This study presents a case using full mouth periodontal treatment, immediate orthodontic treatment for 5 months, implantation with guided bone regeneration and free gingival graft, and prosthetic treatment. Treatments took totally 14 months. Periodontal indicators such as probing pocket depth, bleeding on probing, tooth mobility improved. Also, the patient was satisfied with the esthetic and functional improvement.

• 대한소아치과학회지
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• 제32권4호
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• pp.670-674
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• 2005

과잉치는 치배 형성기에 정상 치판의 과도한 증식의 결과로 발생하며 산발적일 수도 있고 유전적일 수도 있다 발생 빈도는 $1{\sim}3%$이며, 2:1의 비율로 남아에게 호발한다. 주로 상악 전방부에서 많이 발견되며 매복, 영구치의 위치 이상, 정중부 이개, 낭종, 비강으로의 맹출 등과 같은 다양한 합병증을 나타낼 수도 있다. 상악 전방부에서 발견되어지는 과잉치는 치축방향에 따라 위치가 결정되며 상악 전방부 과잉치의 1/3정도는 역위 매복되어 맹출의 가능성이 없지만, 치낭의 치관 부위가 정상적인 관계로 존재하는 한 과잉치의 이동이 일어날 수 있다. 치아의 이동은 경구개, 소구치 부위, 비강까지도 일어날 수 있다. 또한 전상악 수직고경의 성장으로 시간이 지남에 따라 외과적 접근이 어려워질 수 있다. 이에 본 두 증례에서는 역위 매복된 상악 전방부의 과잉치가 구개 측 중앙부까지 이동된 것을 발견하여 외과적으로 제거하였다.

• 한국세라믹학회지
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• 제56권6호
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• pp.521-525
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• 2019

A study was conducted to investigate the possibility of a composite material containing a composite resin as a matrix and hydroxyapatite (HAp) powder as a substitute material for tooth repair. As the content of HAp increased, hardness value (111.9 HV at 9%) increased and flexural strength (73.3 MPa at 9%) decreased. Observation of the microstructure after immersion in a simulated body fluid (SBF) solution confirmed a dense structure due to mutual coagulation and curing. It was thought that fine HAp recrystals were formed with the lapse of time, and they were entangled to form a condensation structure and had a dense structure. In addition, since the activity was shown by the ion migration on the surface of a tooth, it was highly likely that a biocompatible bond occurred during tooth contact. Therefore, it could be used as a substitute material for tooth repair.

• 구강회복응용과학지
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• 제35권3호
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• pp.180-190
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• 2019

병적 치아 이동된 상악 전치를 가진 중등도 치주염 환자에서는 치태 관리를 통한 치주 염증의 해소뿐만 아니라 치아를 재위치 시키기 위한 교정치료가 함께 필요하다. 이 때의 교정치료는 더 적은 힘의 적용과 치아의 저항중심, 최적의 힘 등을 세심하게 고려해야 하는데, 이동하고자 하는 치아에만 적용되는 분절호선은 이동의 예측성을 높여주고, 힘을 조절할 수 있어 보다 효율적이다. 또한 교정치료 시, 고정원으로 사용되는 치아의 원치 않는 움직임을 차단하여 구치 교합 상태를 유지할 수 있는 장치 설계가 필요하며, 이를 위해 다양한 종류의 골성 고정원이 사용될 수 있다. 본 증례에서는 정출되고 변위된 상악 전치를 가진 환자에서, 철저한 치주 치료와 적절한 힘과 역학이 설계된 교정 장치로, 양호한 치료 결과를 얻을 수 있었으므로, 소개하고자 한다.

• Imaging Science in Dentistry
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• 제42권1호
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• pp.47-54
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• 2012

Transmigration of an impacted tooth through the symphyseal suture is a rare and special developmental anomaly of unknown etiology that is unique to the mandibular canine. Maxillary canine transmigration is even rarer. Transmigrated canines are particularly significant due to the aesthetic and functional importance. A maxillary lateral incisor crossing the mid-palatal suture has never been reported in the literature. The aim of this report is to present the first case of simultaneous transmigration of a lateral incisor and canine in the maxilla. The paper also reports four unusual cases of unilateral canine transmigration in the maxilla and mandible and successful eruption of one of the transmigrated mandibular canines following orthodontic traction. Etiology of transmigration and its clinical considerations are also discussed.

• International Journal of Stem Cells
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• 제16권2호
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• pp.202-214
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• 2023

Background and Objectives: To investigate the role of exosomes from periodontal ligament cells (PDLCs) in bone marrow mesenchymal stem cell (BMSC) migration. Methods and Results: Human PDLCs were applied cyclic tension stretching. Exosomes were extracted from cultured PDLCs by ultracentrifugation, then characterized for their size, morphology and protein markers by NTA, TEM and western blotting. The process that PKH26-labeled exosomes taken up by BMSCs was assessed by confocal microscope. BMSC migration was examined by Transwell assay. Exosomes derived from PDLCs were identified. Cyclic tension stretch application on PDLCs can enhance the migration ability of BMSCs through exosomes. The exosomal miRNA expression profiles of unstretched and stretched PDLCs were tested by miRNA microarray. Four miRNAs (miR-4633-5p, miR-30c-5p, miR-371a-3p and let-7b-3p) were upregulated and six (miR-4689, miR-8485, miR-4655-3p, miR-4672, miR-3180-5p and miR-4476) were downregulated in the exosomes after stretching. Sixteen hub proteins were found in the miRNA-mRNA network. Gene Ontology and KEGG pathway analyses demonstrated that the target genes of differentially expressed exosomal miRNAs closely related to the PI3K pathway and vesicle transmission. Conclusions: The exosomes derived from cyclic tension-stretched PDLCs can promote the migration of BMSCs. Alternation of microRNA profiles provides a basis for further research on the regulatory function of the exosomal miRNAs of PDLCs during orthodontic tooth movement.