• Journal of the Korean Wood Science and Technology
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• v.35 no.3
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• pp.70-78
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• 2007

This study explored the efficient dyeing method of aged chestnut wood using the natural dyes extracted from Gardenia jasminoides for, grandiflora, Carthamus tinctorius L., Rhus javanica L., Lithospermum erythrorhizon S. et Z., Caesalpinia sappan L. and Castanea crenata S. et Z.. The color variation of the dyed chestnut woods was also quantitatively evaluated. The wood specimens revealed abundant colors through different dyeing conditions such as dyeing temperature, dye pH, soaking time, and brushing frequency. The chroma and stain concentration of colored woods were calculated with $L^*$, $a^*$ and $b^*$ in order to make color tone measurement. Brushing treatment for colored wood was confirmed as a more economical dyeing method than soaking treatment requiring more time when natural dyeing was done. Furthermore, the desirable tone and shade of color was easily obtained by repetitive brushing treatment using low color tone. During natural dyeing, good color expression was made with high temperature and acidic condition of a dyeing liquor.

• Journal of Korea Entertainment Industry Association
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• v.13 no.8
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• pp.167-180
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• 2019

The purpose of this study is to find out the results of synesthesia speech training using similar language for shaping audiobook text. The audiobook text for training uses Tolstoy's work, and uses similar language of tone, tone, pose, speed, intonation, accent, and expression of emotions. The participants who ten visually impaired trainee in H library were selected for qualitative research. Based on the research questions raised in this study, the results are as follows. First, synesthesia training, in which more than two senses of the five senses work simultaneously in voice training for audio book text shaping, produced the result by visualizing the original purpose, meaning, and background of the text. Second, the use of similar language was helpful in the whole process of expressing the meaning of sentence and dialogue for audiobook text shaping. In addition, although there were some differences among the study subjects, they found commonalities that considered tone, pose, and intonation important. Third, the visually impaired have advanced sensory aspects and memory, which resulted in rapid acquisition of metabolism and acceptance of transmission during training. In addition, the teacher's friendly behavior was a very important key mediator in the training process.

• Science of Emotion and Sensibility
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• v.25 no.3
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• pp.127-134
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• 2022

This study sought to identify the voice user interface (VUI) design parameters that evoked positive user emotions. Six VUI design parameters that could affect emotional user satisfaction were considered. The moderating effects of user gender and the design parameters were analyzed to determine the appropriate conditions for user satisfaction when interacting with the VUI. An interactive VUI system that could modify the six parameters was implemented using the Wizard of OZ experimental method. User emotions were assessed from the users' facial expression data, which was then converted into a valence score. The frequency analysis and chi-square test found that there were statistically significant moderating gender and AI effects. These results implied that it is beneficial to consider the users' gender when designing voice-based interactions. Adult/male/high-tone voices for males and adult/female/mid-tone voices for females are recommended as general guidelines for future VUI designs. Future analyses that consider various human factors will be able to more delicately assess human-AI interactions from a UX perspective.

• Journal of Yeungnam Medical Science
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• v.25 no.1
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• pp.41-49
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• 2008

Background : The central physiological derangement of hemorrhagic fever with renal syndrome (HFRS) caused by hantaan virus (HTNV) is a vascular dysfunction, manifested by hemorrhage, impaired vascular tone and increased vascular permeability. Platelet activating factor (PAF), whose actions are mediated through a specific receptor, is a potent bioactive lipid. PAF has diverse biological functions in the vascular system, such as increasing vascular permeability, adhesion of leukocytes to the endothelium and reduction of cardiac output, which result in hypotension and shock. The goal of the present study was to investigate whether PAF is involved in the pathogenesis of HFRS. For this purpose, we evaluated the effect of HTNV on the expression of PAF receptor (PAF-R) and on the activity of PAF-acetylhydrolase (PAF-AH) instead of PAF because PAF is rapidly degraded by PAF-AH in vivo. Materials and methods : To evaluate the expression of PAF-R, we performed reverse-transcription PCR, western blot and FACS analyses using HTNV-infected human umbilical vein endothelial cells (HUVECs) and non-infected (control) HUVECs. In addition, we measured the activity of plasma PAF-AH in HFRS patients and normal healthy persons. Results : The mRNA and protein expression of PAF-R was increased in HTNV-infected HUVECs compared with control HUVECs at 2 and 3 days post-infection (d.p.i.). FACS analysis showed that HTNV induced the surface expression of PAF-R in HUVECs from 2 d.p.i. The activity of plasma PAF-AH was 2.5-fold lower in HFRS patients than in normal healthy persons. Conclusion : Increased PAF-R expression by HTNV might increase the responsiveness to PAF in endothelial cells. Reduced PAF-AH activity in the blood of HFRS patients might delay PAF degradation. These results suggest that changes in PAF-R and PAF-AH by HTNV might influence to PAF activity and might be involved in the vascular dysfunction of HFRS.

• Journal of Veterinary Clinics
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• v.28 no.4
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• pp.403-407
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• 2011

A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome (PCOS) can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several weeks, the appearance of cysts, suggesting the involvement of a neurogenic component in the pathology of this ovarian dysfunction. To test the hypotheses that the change in sympathetic tone is related to an augmented production of hippocampal and/or ovarian nerve growth factor (NGF), and that this abnormally elevated production of NGF contributes to the induction of PCOS induced by EV. The animals were sacrificed after PCOS induction and the ovaries and hippocampus were sectioned and compared to the normal control. The expression of NGF was measured by immunohistochemical staining and Western blot analysis in the ovaries and hippocampus. EV-induced PCOS showed significant increase of ovarian NGF expression. Immunohistochemical expression of NGF was confined to the follicular cells and interstitial cells. Hippocampal NGF expression was not significantly changed. In conclusion EV-induced PCOS was related to the ovarian sympathetic activation which was mediated by NGF.

• Journal of Digital Convergence
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• v.15 no.6
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• pp.377-383
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• 2017

In this thesis, Improvisation of Jazz Vocal that can be characterized as Jazz music, namely practice of Scat suggest that way of applied approach that root position of chord and chord tones. Scat plays a solo using reproduced tunes of meaningless scat syllable that is not use the lyrics and melodies, which are written in a score. For this, Using the root position of chord is a reference point that Jazz vocal constructs a musical melody. Singing person can develop that reference point from simple scat to develop increasingly complex scat and can express that musical expression and communion. It analyzed the music functionally with a standard Jazz music 'All of me' as the center from composition of chord tone that improvise song to bass line, bass scat, analysis of chord tones arpeggio and expression. In this thesis, the improvisation of a Jazz vocal that may seem somewhat abstruse and complex could be relatively easy to construct through a gradual approach.

• Journal of the Korean housing association
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• v.23 no.1
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• pp.89-96
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• 2012

The purpose of this study is to find out the characteristics of activity areas according to the age difference and provide the alternatives for space planning of activity areas in classroom of childcare centers. This study used the content analysis method for field survey data collected from 36 classrooms of 9 childcare centers in the Daejeon area. Floor plans were converted to Autocad drawings to analyze the characteristics of activity areas. The results of this study were as follows; 1) In case of 0 to 2-year-old classrooms, they had 6 activity areas such as gross-motor area, role play, block building, language, creative expression, exploration/manipulation area. The activity area with the most low frequency was gross-motor area. 2) In case of 0 to 2-year-old classrooms, the size of activity area was in order of gross-motor area > role play > block building > language > creative expression > exploration/manipulation area. In case of 3 to 5-year-old classrooms, the size of activity area was in order of language > art > role play > math > block building > science > tone and rhythmic area. 3) The central areas with easy access in 0 to 2-year-old classrooms were Large-motor and Imaginary Play Areas. Also, more isolated areas were Manupulatives and Block Areas. The central areas with easy access in 3 to 5-year-old classrooms were Arts, Numbers and Manupulatives. While more isolated areas were Music, Movement and Science Areas.

• International Journal of Advanced Culture Technology
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• v.7 no.4
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• pp.125-136
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• 2019

The radish skin and radish greens are an edible part of the radish. But they are removed before eating the radish and used as a byproduct or an animal feed material because of their tough and rough texture. Melanin is a pigment that gives colour to our skin. But increased production of melanin can turn into benign or malignant tumours. These days due to global warming, the amount of Ultra violet (UVB) rays has been extensively increased with sunlight. Due to this, a phenomenon called exogenous photo aging is widely observed for all skin colour and types. As a result of this phenomenon, a set of enzymes called matrix metalloproteinases (MMP's) that serves as degradation enzymes for extracellular matrix proteins mainly collagen is increased, causing depletion in collagen and resulting in early wrinkles formation. Therefore in our study we used the murine melanoma cell line B16/F10 to study the melanogenesis inhibition by Heated radish extract (HRE) in vitro and we used HRM-2 hair less mice exposed to artificial UVB for checking the efficacy of Heated radish extract in vivo. Furthermore, we prepared a 3% Heated radish extract (HRE) cream and checked its effects on human skin. Our results have clearly demonstrated that Heated radish extract (HRE) have potently suppressed the tyrosinase activity and melanin production in B16/F10 cells. It had also reduced the expression of components involved in melanin production pathway both transcriptionally and transitionally. In in vivo studies, HRE had potently suppressed the expression of MMP's and reduced the wrinkle formation and inhibited collagen degradation. Moreover, on human skin, ginseng cream increased the resilience, skin moisture and enhanced the skin tone. Therefore in light of these findings, we conclude that HRE is an excellent skin whitening and antiaging product.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.22 no.5
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• pp.23-28
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• 2022

Today, the online market has grown rapidly due to the development of digital platforms and the pandemic situation. Therefore, unlike the existing offline market, the distinctiveness of the online market has prompted users to check online reviews. It has been established that reviews play a significant part in influencing the user's purchase intention through precedents of several studies. However, the current review writing method makes it difficult for other users to understand the writer's emotions by expressing them through elements like tone and words. If the writer also wanted to emphasize something, it was very cumbersome to thicken the parts or change the colors to reflect their emotions. Therefore, in this paper, we propose a technique to check the user's emotions through facial expression recognition using a camera, to automatically set colors for each emotion using research on existing emotions and colors, and give colors based on the user's intention.

• The Korean Journal of Physiology and Pharmacology
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• v.26 no.4
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• pp.255-262
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• 2022

Oxytocin is a neuropeptide produced primarily in the hypothalamus and plays an important role in the regulation of mammalian birth and lactation. It has been shown that oxytocin has important cardiovascular protective effects. Here we investigated the effects of oxytocin on vascular reactivity and underlying the mechanisms in human umbilical vein endothelial cells (HUVECs) in vitro and in rat aorta ex vivo. Oxytocin increased phospho-eNOS (Ser 1177) and phospho-Akt (Ser 473) expression in HUVECs in vitro and the aorta of rat ex vivo. Wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase (PI3K), inhibited oxytocin-induced Akt and eNOS phosphorylation. In the rat aortic rings, oxytocin induced a biphasic vascular reactivity: oxytocin at low dose (10^-9-10^-8 M) initiated a vasorelaxation followed by a vasoconstriction at high dose (10^-7 M). L-NAME (a nitric oxide synthase inhibitor), endothelium removal or wortmannin abolished oxytocin-induced vasorelaxation, and slightly enhanced oxytocin-induced vasoconstriction. Atosiban, an oxytocin/vasopressin 1a receptor inhibitor, totally blocked oxytocin-induced relaxation and vasoconstriction. PD98059 (ERK1/2 inhibitor) partially inhibited oxytocin-induced vasoconstriction. Oxytocin also increased aortic phospho-ERK1/2 expression, which was reduced by either atosiban or PD98059, suggesting that oxytocin-induced vasoconstriction was partially mediated by oxytocin/V1aR activation of ERK1/2. The present study demonstrates that oxytocin can activate different signaling pathways to cause vasorelaxation or vasoconstriction. Oxytocin stimulation of PI3K/eNOS-derived nitric oxide may participate in maintenance of cardiovascular homeostasis, and different vascular reactivities to low or high dose of oxytocin suggest that oxytocin may have different regulatory effects on vascular tone under physiological or pathophysiological conditions.