• Asian Pacific Journal of Cancer Prevention
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• v.17 no.sup1
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• pp.43-47
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• 2016

Second-hand tobacco smoke (SHS) exposure at home, especially among children, is a serious issue in Viet Nam. During the past decade, much effort has been taken for tobacco control in the country, including various prgorammes aiming to reduce SHS exposure among adults and children. This article analysed trends and factors associated with SHS exposure at home among school children aged 13-15 in Viet Nam, using the Global Youth Tobacco Surveys conducted in 2007 and 2014. Descriptive and inferential statistical methods with logistic regression were applied. Overall, there was a significant reduction in the level of exposure, from 58.5% (95%CI: 57.6-59.3) in 2007 to 47.1% (95%CI: 45.4-48.8) in 2014. Of the associated factors, having one or both parents smoking was significantly associated with the highest odds of SHS exposure at home (OR=5.0; 95%CI: 4.2-6.1). Conversely, having a mother with a college or higher education level was found to be a protective factor (OR=0.5; 95%CI: 0.3-0.8).

• Korean Journal of Health Education and Promotion
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• v.22 no.2
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• pp.77-95
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• 2005

Objectives: This study measured the extent of local legislators' support for tobacco control policies and identified the predictors of that. Methods: Local legislators, from 21 Gu in Seoul Metropolitan City, underwent a self-administrated questionaire during the 6-week period from December 1, 2004 to January 15, 2005. Multiple linear regression model was used to assess relationships between five groups of variables(political factors including political ideology, personal characteristics, tobacco experiences, tobacco knowledge, contact with local health officers) and support for tobacco control policies based on an 11-item scale. Results: The rates of support for 'penalizing merchants who sell cigarettes to minors' and 'instituting a law mandating that parents should not smoke in a car when children are present' were highest as 87.5% and 82.0% respectively, and those for 'increasing price of cigarettes' and 'regulating stores that sell cigarettes' were lowest as 52.2% and 51.7% respectively. Support was higher among local legislators who thought government had a duty to promote healthy life styles, knew second-hand smoke could cause lung cancer, knew tobacco caused more deaths than alcohol. Support among ex-smokers and nonsmokers was higher than current smokers. Conclusions: The findings indicate that local legislators who oppose tobacco control measures may not be opposed to tobacco control per se, but are more generally opposed to a government role in health promotion, Thus, Tobacco control advocates need to be more attentive to the way tobacco control issues are framed for particular legislators. Further, they could work to increase tobacco knowledge among local legislators.

• Journal of the Korean Society of Tobacco Science
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• v.1 no.2
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• pp.93-102
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• 1979

Chemical compositions of Flue - cured and Burley tobacco leaf and smoke were analyzed to find out simple correlation between compositions. Based on the simple correlation ( $r$ ) data, four regression equations were obtained for dry condensate and nicotine in smoke as follows, $Y_{FT}=\;0.816+4.638X_1+0.346X_2$......................................(1) $Y_{BT}=\;0.235+0.884X_3-0.088X_4$......................................(2) $Y_{FN}=\;0.015+0.090X_5+0.476X_1$......................................(3) $Y_{BN}=-0.026+0.101X_3-0.006X_4$.........................................(4) where, $Y_{FT}$ : dry condensate (mg/cig.) in cigarette smoke of Flue-cured $Y_{BT}$ : dry condensate (mg /cig. ) in cigarette smoke of Burley $Y_{FN}$ : nicotine contents (mg/cig.)in cigarette smoke of Flue-cured $Y_{BN}$ : nicotine contorts (mg/cig. ) in cigarette smoke of Burley $X_1$ : total alkaloid contents (%) of Flue-cured $X_2$ : curde ash contents (%)of Flue -cured $X_3$ : alcohol -benzene extract contents (%) of Burley $X_4$ : curde ash contents (%) of Burley $X_5$ : hexane extract content (%) of Flue -cured Standard deviation for regressions equations were obtained respectively. equation(1),$\pm$3.16 : equation (2),$\pm$1.94 : equation (3),$\pm$0.35 , equation (4) $\pm$ 0.33. Regression equations between dry condensate and nicotine contorts in cigarette smoke were also obtained in the forms of equation(5) and(6) $Y_{FN}$= 0.274 $Y_{FT}$- 3.259............................(5) $Y_{BN}$= 0.249 $Y_{BT}$ - 2.093.............................(6) Standard deviations, $\pm$ 0.061 and $\pm$ 0.152, were obtained for regression equation(5) and (6) respectively.

• Journal of the Korean Society of Tobacco Science
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• v.15 no.1
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• pp.98-105
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• 1993

The chemical components of tobacco stalk, stems of tobacco caltivations, were analyzed and reconstituted tobacco sheet were made from the stalk and tobacco hyproducts by rolled and paper reconstitute tobacco sheet making process. The results were summarized as follow 1. In the viewpoint of chemical components, nicotine, total nitrogen and ash content of stalk were lower than those of stems, but crude fiber was two times higher than stems. 2. Reconstituted tobacco sheet of tobacco stalk blended were improved fragility and specific gravity than those of control. 3. Smoke components delivery of cigarette made from reconstituted tobacco sheet of tobacco stalk blended were similar to control cigarette. 4. According to the result of ranking preference test for control and sample cigarette, were not recognized significant at 5 percent level. 5. According to the result of areas test for control and sample cigarette, were not recognized significant at 5 percent level. 6. Optimum stalk blend ratio of reconstituted tobacco sheet manufacturing was from about 20 to 40% to the rolled sheet, and was from about 5 to 10% to the paper making process tobacco sheet.

• Journal of the Korean Society of Tobacco Science
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• v.22 no.2
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• pp.176-183
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• 2000

This study was conducted to compare the volatile components of lamina(cutter group) and midrib of flue-cured tobacco leaves by two analytical methods, Curie-Point pyrolysis and Purge & Trap headspace technique. The pyrolysis of lamina and midrib part of tobacco leaves was performed at the temperature of $330^{\circ}C$, $650^{\circ}C$, and $920^{\circ}C$ by Curie-Point Pyrolyzer, and 33 compounds were identified in the pyrolyzates by GC/MSD. The composition of the components identified showed a quite difference between lamina and midrib. However, the amount of the pyrolyzed products from the both of lamina and midrib was increased with temperature increase except that of acetic acid, furfural, and nicotine. The content of phenolic compounds including phenol, 4-methyl phenol, and 3-methyl phenol was higher in midrib than in lamina, while that of furan compounds such as 2,3-dihydrobenzofuran, 5-hydroxymethyl furfural, was high in lamina. Interestingly, acetamide, 2-propenamide and 3-acetoxy pyridine were not defected in the pyrolyzates of lamina. By Purge & Trap headspace technique, 28 volatile components were identified in both lamina and midrib. The composition of the identified compounds and their chromatograpic patterns also showed the complete difference between the two. The content of solanone, $\beta$-damascone, $\beta$-damascenone, and megastigmatrienones, key components of tobacco aroma, was much higher in lamina than in midrib. The results indicate that lamina contains much more carbonyl compounds known to enhance the smoke taste of cigarette, whereas midrib takes nitrogenous and phenolic compounds, which are known to cause a deteriorate effect of smoke such as irritation.

• Journal of the Korean Society of Tobacco Science
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• v.24 no.1
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• pp.67-73
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• 2002

In light of addressing consumer health concern, coping with anti-tobacco movement, and promoting new product, tobacco industry is actively pursuing to make a new generation of cigarettes with low tar and nicotine deliveries, and less harmful substances. Low tar and low nicotine cigarettes increases their market shares dramatically world wide, especially in KT&G, multinational tobacco companies, EU countries, even in China regulated by CNTC to set up yearly target to lower tar and nicotine deliveries. On the other hand, to design a new cigarette with reduced harmful substances begins to gain speed. The "modified Hoffmann list" publishes thirty plus substances in tobacco leaf and main smoke stream, which is the prime suspect causing health problems. Various ways and means are developed to reduce such components including new tobacco breeds, new curing method, tobacco leaf treatment before processing, selected filtration system, innovated casing system to reduce free radicals, as well as some non conventional cigarette products. In TSRC held this year, the main topic is related to reduce tobacco specific nitrosamines in tobacco leaf. The new generation of cigarette is in the horizon. It still needs a lot help to produce commercial products with satisfied taste and aroma characters. The flavor industry is not regulated by many governments demanding which ingredients might or might not be for tobacco use. However, most of the cigarette companies self impose a list of ingredients to guide flavor suppliers to design flavors. Unfortunately, the number of ingredients in those lists is getting shorter every year. It is understandable that the health is not the only reason. Some cigarette companies are playing safe to protect the company from potential lawsuit, while others are just copying from their competitors. Moreover, it is obvious that it needs more assistance from casings and flavors to design new generation of cigarettes with missing certain flavor components in tobacco leaf and main smoke stream. These flavor components are either non-existed or at lower level at new form of cured tobacco leaf or filtered in the main smoke stream along with reduced harmful substances. The use of carbon filters and other selected filtration system poses another tough task for flavor system design. Specific flavor components are missing from the smoke analysis data, which brings a notion of "carbon taste" and "dryness" of mouth feel. It is ever more demanded by cigarette industry to flavor suppliers to produce flavors as body enhancer, tobacco notes, salivating agents, harshness reducer, and various of aromatic notes provided they are safe to use. Another trend is that water based flavor or flavor with reduced ethanol as solvent is gaining popularity. It is preferred by some cigarette companies that the flavor is compounded with all natural ingredients or all ingredients should he GMO free. The new generation of cigarettes demands many ways of new thinking process. It is also vital for tobacco industry. It reflects the real needs for the consumers that the cigarette product should be safe to use as well as bearing the taste and aroma characters smokers always enjoyed. An effective tobacco flavor system is definitely a part of the equation. The global trend of tobacco industry is like trends of any other industries lead by consumer needs, benefited with new technology availability, affected by the global economy, and subjected for various rules and regulations. Anti-tobacco organizations and media exceptionally scrutinize cigarette, as a legal commercial product. Cigarette is probably the most studied commercial product for its composition, structure, deliveries, effects, as well as its new developmental trend. Therefore, any new trend of cigarette development would be within these boundaries. This paper is trying to point out what it would be like for tobacco industry in the next few yews and what concerns the tobacco industry. It focuses mostly on the efforts to produce safer cigarettes. It is such a vital task for the tobacco industry and its affiliate industries such as cigarette papers, filters, flavors, and other materials. The facts and knowledge presented in this paper might be well known for the public. Some of the comments and predictions are very much personal opinion for a further discussion.

• Journal of the Korean Society of Tobacco Science
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• v.33 no.1
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• pp.28-38
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• 2011

This experiment was conducted as a part of Asia collaborative study on purpose of verifying the difference between CM6 and CM7 including 3R4F for reference. It carried out using various analytical categories for example, main stream, sidestream and Av. smoke. Additional analysis such as physical properties, blending ratio, combustibility and general leaf component analysis also implemented in order to investigate the difference. We complied with ISO standard and CORESTA recommended method during analytical operating procedures. In this study, we described that comparative analytical result for CM6 and CM7 known as reference or monitoring cigarettes including 3R4F for reference. All sample cigarettes were conditioned at $22^{\circ}C$, 60% relative humidity for 48 hours. Av. Smoke, MS and SS smoke analysis were performed over five times with two smoking condition, ISO and Health Canada with the exception of Av. smoke analysis. We complied with ISO standard method during analytical operating procedures. And, we conducted additional analysis, such as physical properties, blending ratio, combustibility and leaf component analysis also in order to investigate the difference. In conclusion, we found out some differences between CORESTA monitoring cigarette No. 6 and No 7. The smoke components such as total particulate matters, NFDPM, nicotine and carbon monoxide contents of CM7 were a little lower than CM6. And, these phenomena were the same as not only main stream smoke but also side stream smoke and Av. smoke. This tendency was consistent with ISO and Health Canada smoking condition. Besides, leaf constituents' color of CM7 was darker than CM6. In case of combustibility, it showed short combustion time approximately 30 seconds.

• Journal of the Korean Society of Tobacco Science
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• v.36 no.1
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• pp.20-25
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• 2014

As part of a balanced testing battery, subchronic inhalation studies on rats are performed to ensure that proposed cigarette modifications do not increase the toxicity of smoke and to demonstrate any instances where a modification may actually contribute to harm reduction. For subchronic inhalation studies with aerosols, the OECD suggests an exposure regimen of 6 hours/day (OECD Guideline 413, 1981), but alternative regimens have also been published: 1 hour/day and $2{\times}1$ hour/day. The aim of this study was to validate a rodent nose-only exposure system for the assessment of inhalation toxicity of cigarette smoke. In this study, cigarette smoke exposure system is consisted of cigarette smoke generator, smoke concentration adjusting system, and 20-port nose-only exposure system. Male SD rats were exposed for 35 days ($2{\times}1$ hour/day) to 3R4F Reference cigarette smoke and analysed major monitoring items of OECD Gudeline 413. WTPM, was measured in the test atmosphere, respiratory function (Buxco Biosystems) during exposure, postexposure urinary exposure biomarkers and alveolar neutrophiles in BAL fluid (Day 35) were evaluated. Validation demonstrated steady WTPM ($257{\pm}20ug/L$, $502{\pm}27ug/L$) and spatial uniformity (<10%). Nose port temperature ($22{\sim}26^{\circ}C$ and RH (45~75%) were acceptable over 35 days. Reductions in respiratory rate and minute volume and increase in the neutrophiles in BALF and the urinary exposure biomarkers were observed cigarette smoke dose dependently. This validation and 35-day inhalation study has shown that the rodent nose-only exposure system may be useful in the inhalation toxicity assessment of cigarette smoke.

• Journal of Environmental Health Sciences
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• v.44 no.1
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• pp.90-97
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• 2018

Objectives: Thirdhand smoke (THS) refers to residual tobacco smoke pollutants that remain after cigarette smoking. The purpose of this study was to determine predictors of the belief among adults in Korea that THS is harmful to children. Methods: A population-based sample of 3,000 adults (${\geq}19$ years) among a web-based panel in Korea was obtained in November 2016. The respondents filled out questionnaires, including THS beliefs, smoking status, presence of voluntary smoke-free rules at home, and support for the implementation of smoke-free regulations at home. THS beliefs were assessed with a statement that staying in a room today where people smoked yesterday can harm the health of children. Results: Overall, 92.2 % of adults believed that THS exposure could harm the health of children. Respondents who were nonsmokers, believed that SHS exposure were associated with pneumonia of children, lived in home with complete smoke-free rule at home, and supported the implementation of smoke-free regulation at home were more likely to believe that THS could harm for health of children. Conclusions: The majority of Korean adults believed that THS exposure could harm the health of children. Predictors identified in the study can be useful to address the risk of THS beliefs and promote implementation of tobacco control policies.

• Journal of the Korean Society of Tobacco Science
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• v.13 no.2
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• pp.27-33
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• 1991

Current studies indicated that emphysema in smokers might be due, in part, to the local suppression of G, -protease inhibitor(u, -Pl) in lung by reactive oxygen species in cigarette smoke or smoke-activated lung neutrophiles. In the present works, we examined the possibility that a measure which inactivated $\alpha$l-Pl by cigarette smoke could be an alternative method to evaluate the cigarette quality, In order to determine the inactivation of $\alpha$1, -Pl, trypsin inhibitory capacity(TIC) was assayed. A rapid loss of $\alpha$1, -Pl activity occurred when $\alpha$1-Pl solutions was exposed the gas phase or total particulate matter(TPM) obtained from various brands. The inactivation of $\alpha$1-Pl by gas phase was dependent upon the number of puffs and the age of the smoke. However, that by TPM was rather decreased since 2 puffs and also showed no more change over 24hrs after exposing. Inactivation of $\alpha$1-Pl determined by our suggested method(5 puffs, 24hours of aging after exposing) using various commercial cigarettes exhibited that high tar brands has inactivated it more strongly than low tar cigarettes. But the ability of some brands to inactivate $\alpha$1-Pl does not correlate with the content of tar or nicotine. These results so여esc that the degree of $\alpha$1-Pl inactivation by cigarette smoke may be a useful index for the evaluation of cigarette quality and that it should be also contribute to the manufacture of less hazardous cigarettes.