• The Journal of Korean Institute of Communications and Information Sciences
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• v.11 no.1
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• pp.25-39
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• 1986

In this paper, we analyze the performance, particularly the flow control mechanism, of the CCITT X.25 protocol in a packet-switched network. In this analysis, we consider the link and packet layers separately, and investigate the performance in three measures; normalized channel throughput, mean transmission time, and transmission efficiency. Each of these measures is formulated in terms of given protocol parameters such as windos size, $T_1$ and $T_2$ values, message length, and so forth. We model the service procedure of the inpur traffic based on the flow control mechanism of the X.25 protocol, and investigate the mechanism of the sliding window flow control with the piggybacked acknowlodgment scheme using a discrete-time Markov chain model. With this model, we study the effect of variation of the protoccol parameters on the performance of the X.25 protocol. From the numerical results of this analysis one can select the optimal valuse of the protocol parameters for different channel environments. it has been found that to maintain the trasnmission capacity satisfactorily, the window size must be greater than or equal to 7 in a high-speed channel. The time-out value, $T_1$, must carefully be selected in a noisy channel. In a normal condition, it should be in the order of ls. The value of $T_2$ has some effect on the transmission efficiency, but is not critical.

• Journal of the Society of Disaster Information
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• v.16 no.4
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• pp.650-657
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• 2020

Purpose: In this study, the effectiveness of pilot project of PLSP (Priority Lane and Signal Preference) system, which was operated in Cheongju City, was analyzed. Method: The priority signal was operated by a police officer switching to a blue signal when approaching a fire truck through CCTV, and the priority lane of emergency vehicles was displayed on the road to enable preferential traffic. VISSIM simulation analysis was performed for the 1.2km section (3.8km) of the pilot project section and vehicle data was analyzed for some of the test operation sections. Result: Simulation analysis shows that the moving speed of the emergency vehicle can be increased by 42 km/h with the introduction of PLSP, which can be increased by approximately twice the speed. Travel time was reduced by about 3 minutes, and considerable improvements of 69% compared to cities that are not operating was analyzed. The pilot operation of Cheongju City showed a time-shortening effect of about two minutes on average, with the average time reaching 4 minutes and 14 seconds in the first period and the average time reaching 5 minutes and 40 seconds in the second period. Conclusion: The system has been shown to be effective in minimizing time-to-site arrival of emergency vehicles.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.5
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• pp.10-24
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• 2007

In the dissertation, a power conversion system for fuel cell is composed of a PWM inverter with LC filter in order to convert fuel cell voltage to a single phase 220[V]. In addition, new insulated DC-DC converters are proposed in order that fuel cell voltage is boosted to 380[V]. In this paper, it requires smaller components than existing converters, which makes easy control. The proposed DC-DC converter controls output power by the adjustment of phase-shift width using switch $S_5\;and\;S_6$ in the secondary switch which provides 93-97[%] efficiency in the wide range of output voltage. Fuel cell simulator is implemented to show similar output characteristics to actual fuel cell. Appropriate dead time td enables soft switching to the range where the peak value of excitation current in a high frequency transformer is in accordance with current in the primary circuit. Moreover, appropriate setting to serial inductance La reduces communication loss arisen at light-load generator and serge voltage arisen at a secondary switch and serial diode. Finally, TMS320C31 board and EPLD using PWM switching technique to act a single phase full-bridge inverter which is planed to make alternating current suitable for household

• Journal of Pharmaceutical Investigation
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• v.33 no.4
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• pp.311-317
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• 2003

Felodipine is a calcium antagonist that lowers blood pressure by reducing peripheral resistance by meas of a direct, selective action on smooth muscle in arterial resistance vessels. Futhermore, it have been approved for the effective in angina pectoris and cardiac failure. The purpose of the present study was to evaluate the bioequivalence of two felodipine extended release (ER) tablets, Splendil (YuHan Corporation) and Stapin (Hana Pharmaceutial Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The felodipine release from the two felodipine formulations in vitro was tested using KP VIII Apparatus II method at pH 6.5 buffer solution. Twenty six healthy male subjects, $22.73{\pm}1.78$ years in age and $66.66{\pm}7.28\;kg$ in body weight, were divided into two groups and a radomized $2{\times}2$ cross-over study was employed. After two tablets containing 5 mg as felodipine were orally administered, blood sample was taken at predetermined time intervals and the concentrations of felodipine in serum were determined using column-switching HPLC method with UV detector. The dissolution profiles of two formulations were similar at pH 6.5 buffer solution. Besides, the pharmacokinetic parameters such as $AUC_t,\;C_{max}\;and\;T_{max}$ were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t\;and\;C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the Splendil were 2.53%, 1.32% and 18.32% for $AUC_t,\;C_{max}\;and\;T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance rage of log(0.86) to log(1.25) $(e.g.,\;log(0.86){\sim}log(1.20)\;and\;log(0.89){\sim}log(1.23)\;for\;AUC_t,\;C_{max},\;respectively)$. Thus, the criteria of the KFDA guidelines for the bioequivalence was satisfied, indicating Stapin ER tablet and Splendil ER tablet are bioequivalent.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.20 no.11
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• pp.181-188
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• 2019

The migration path of a multiple-generation technology that occurs during a technological substitution by a new technology is important to understanding the phenomenon of technological substitution, and can contribute to understanding the process of technological innovation. This research defines the concept of migration path and develops a model of the types of migration paths by multiple dimensions (actor, generation, and time) in a multiple-generation technology. Based on a literature review and tracking of migration paths according to multiple dimensions, the definitions and types of migration paths were provided, and the accuracy of the model was verified based on a case study of the semiconductor industry. The migration paths of suppliers are modeled with three types (switching, leapfrogging, and new entrance paths), and the migration paths of customers are modeled with four types (switching, leapfrogging, new entrance, and diffusion paths) in a multiple-generation technology. This research will be useful for understanding the migration paths in the phenomenon of technological substitution, and can be applied to other industries in addition to the semiconductor industry, including various actors. In addition, suppliers and customers can understand technological substitution and can establish a technology strategy against their competitors.

• Journal of Pharmaceutical Investigation
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• v.41 no.2
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• pp.117-123
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• 2011

Loxoprofen sodium, a 2-phenylpropionate non-steroidal anti-inflammatory drug (NSAID), has marked analgesic and antipyretic activities and relatively weak gastrointestinal ulcerogenicity. The purpose of the present study was to evaluate the bioequivalence of two loxoprofen sodium tablets, Hana loxoprofen sodium tablet (Hana Pharm. Co., Ltd.) and Dongwha Loxonin$^{(R)}$ tablet (Dongwha Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The in vitro release of loxoprofen from the two loxoprofen sodium formulations was tested using KP IX Apparatus II method with various dissolution media. Twenty four healthy Korean male volunteers, $22.83{\pm}1.862$ years in age and $69.92{\pm}9.14$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ crossover study was employed. After a single tablet containing 60 mg as loxoprofen sodium was orally administered, blood samples were taken at predetermined time intervals and the concentrations of loxoprofen in serum were determined using a online column-switching HPLC method with UV/Vis detection. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC^t$, $C_{max}$ and $T_{max}$ were calculated, and computer programs (Equiv Test and K-BE Test 2002) were utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and un-transformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, Dongwha Loxonin$^{(R)}$ tablet, were 2.03, 2.99 and -9.49% for $AUC_t$, $C_{max}$, and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log0.8 to log1.25 (e.g., log0.9831~log1.0535 and log0.9455~log1.1386 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Hana loxoprofen sodium tablet was bioequivalent to Dongwha Loxonin$^{(R)}$ tablet.

• The KIPS Transactions:PartC
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• v.12C no.1 s.97
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• pp.83-96
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• 2005

The multichannel switch is an architecture widely used for ATM (Asynchronous Transfer Mode). It is known that the fault tolerant characteristic can be incorporated into the multichannel crossbar switching fabric. For example, if a link belonging to a multichannel group fails, the remaining links can assume responsibility for some of the traffic on the failed link. On the other hand, if a fault occurs in a switching element, it can lead to erroneous routing and sequencing in the multichannel switch. We investigate several fault localization algorithm in multichannel crossbar ATM switches with a view to early fault recovery. The optimal algorithm gives the best performance in terms of time to localization but it is computationally complex which makes it difficult to implement. We develop an on-line algorithm which is computationally more efficient than the optimal one. We evaluate its performance through simulation. The simulation results show that the Performance of the on-line algorithm is only slightly sub-optimal for both random and bursty traffic. There are cases where the proposed on-line algorithm cannot pinpoint down to a single fault. We enumerate those cases and investigate the causes. Finally, a fault recovery algorithm is described which utilizes the information provided by the fault localization algorithm The fault recovery algorithm providesadditionalrowsandcolumnstoallowcellstodetourthefaultyelement.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.29 no.11B
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• pp.938-945
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• 2004

This paper describes the problems of the existing two multi-layer routing policies(policy 1 and policy 2) and suggests new multi-layer routing policy(policy 3) which is established the packet LSP by inquiry on packet LSP lambda routing tables for GMPLS based optical If Network. All policies of multi-layer routing schemes first try to allocate a newly requested electrical path to an existing optical path that directly connects the source and destination nodes. U such a path is not available, all policies employ different procedures. Policy 1 tries to find available existing optical paths with two or more hops that connect the source and destination nodes and policy 2 tries to establish a new one-hop optical path between source and destination nodes. Policy 3 tries to establish a new one-hop optical path by inquiry on information of the packet LSP lambda routing tables between source and destination nodes. The performances of the three multi-routing policies are evaluated by computer simulation. Simulation results show that policy 3 is the excellent of routing time and traffic acceptance capabilities compare to existing two polices if p is large, where p is the number of packet-switching-capable ports p.

• Korean Journal of Optics and Photonics
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• v.13 no.2
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• pp.146-150
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• 2002

1.55${\mu}{\textrm}{m}$ PnpN optical thyristor as a smart optical switch has potential applications in advanced optical communication systems. PnpP optical thyristors operating at 1.55${\mu}{\textrm}{m}$ are proposed and fabricated for the first time. In the optical thyristors, we employ InGaAs/InP multiple quantum well (MQW) for the active n- and p-layers. The thyristors show sufficiently nonlinear s-shape I-V characteristics and spontaneous emission. In the OFF-state, the device has a high-impedance up to switching voltage of 4.03(V). On the other hand, it has low-impedance and emits spontaneous light as a light-emitting diode in the ON-state voltage of 1.77(V), and switching voltage is changed under several light input conditions. It can be used as a header processor in optical asynchronous transfer mode (ATM), as a hard limiter in optical code division multiple access (CDMA) and as a wavelength converter in optical WDM systems.

• Korean Journal of Clinical Pharmacy
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• v.20 no.3
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• pp.235-241
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• 2010

Bambuterol hydrochloride, dimethylcarbamic acid 5-[2-(1,1-dimethylethyl)amino-1-hydroxyethyl]-1,3-phenylene ester hydrochloride, is the prodrug of active ${\beta}_2$-adrenergic metabolite terbutaline. The purpose of the present study was to evaluate the bioequivalence of two bambuterol hydrochloride tablets, $Bambec^{(R)}$ tablet 10 mg (Yuhan Co., Ltd.) and Bambucol tablet 10 mg (Sam Chun Dang Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). In vitro release of bambuterol from two bambuterol hydrochloride formulations was tested using KP VIII Apparatus II method with various dissolution media. Twenty eight healthy male Korean volunteers, $23.86{\pm}1.65$ years in age and $68.98{\pm}9.58$ kg in body weight, were divided into two groups and a randomized $2{\times}2$ cross-over study was employed. After two tablets containing 10 mg as bambuterol hydrochloride were orally administered, blood samples were taken at predetermined time intervals, and the concentrations of bambuterol in serum were determined using column switching HPLC with UV detector. The dissolution profiles of two formulations were similar in all tested dissolution media. The pharmacokinetic parameters such as $AUC_t$, $C_{max}$ and $T_{max}$ were calculated, and ANOVA test with K-BE Test 2002 was utilized for the statistical analysis of the parameters using logarithmically transformed $AUC_t$, $C_{max}$ and untransformed $T_{max}$. The results showed that the differences between two formulations based on the reference drug, $Bambec^{(R)}$, were -8.10%, -3.82% and 12.65% for $AUC_t$, $C_{max}$ and $T_{max}$, respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log 0.8 to log 1.25 (i.e., log 0.8093~log 1.0302 and log 0.8564~log 1.1280 for $AUC_t$ and $C_{max}$, respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Bambucol tablet 10 mg was bioequivalent to $Bambec^{(R)}$ tablet 10 mg.