• The Transactions of The Korean Institute of Electrical Engineers
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• v.56 no.9
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• pp.1648-1654
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• 2007

In this paper, we consider the design of $H_\infty$ high-gain state feedback control for time-delayed linear systems with limited actuator capacities. The high-gain control means that the control permits the predetermined degree of saturation. Based on new Lyapunov-Krasovskii functional, we derive a result in the form of matrix inequalities. The matrix inequalities are consisted of LMIs those confirm the positive definiteness of Lyapunov- Krasovskii functional, satisfaction of predetermined degree of saturation, reachable set and $L_2$ gain constraint. The result is dependent on the bound of time-delay and its rate, predetermined degree of saturation, actuator capacity, and the allowed size of disturbances. Finally, we give a numerical example to show the effectiveness and usefulness of our result.

• Proceedings of the Korean Nuclear Society Conference
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• 1997.10a
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• pp.244-250
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• 1997

The mean time to failure (MTTF) expressing the mean value of the system life is a measure of system effectiveness. To estimate the remaining life of component and/or system, the dynamic mean time to failure concept is suggested. It is the time-dependent Property depending on the status of components. The Kalman filter is used to estimate the reliability of components using the on-line information (directly measured sensor output or device-specific diagnostics in the intelligent sensor) in form of the numerical value (state factor). This factor considers the persistency of the fault condition and confidence level in measurement. If there is a complex system with many components, each calculated reliability's or components are combined, which results in the dynamic MTTF or system. The illustrative examples are discussed. The results show that the dynamic MTTF can well express the component and system failure behaviour whether any kinds of failure are occurred or not.

• International Journal of Control, Automation, and Systems
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• v.6 no.1
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• pp.1-14
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• 2008

This paper presents a convex optimization method for observer-based mixed $H_2/H_{\infty}$ control design of linear systems with time-varying state, input and output delays. Delay-dependent sufficient conditions for the design of a desired observer-based control are given in terms of linear matrix inequalities (LMIs). An observer-based controller which guarantees asymptotic stability and a mixed $H_2/H_{\infty}$ performance for the closed-loop system of the linear system with time-varying delays is then developed. A Lyapunov-Krasovskii method underlies the observer-based mixed $H_2/H_{\infty}$ control design. A numerical example with simulation results illustrates the effectiveness of the methodology.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.61 no.7
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• pp.1019-1023
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• 2012

This paper considers a model predictive control problem of discrete-time constrained systems with time-varying delay. For this problem, a delay dependent state feedback control approach is used to achieve asymptotic stabilization of systems with input constraints. Based on Lyapunov stability theory, a new stability condition is obtained via linear matrix inequality formulation to find cost monotonicity condition of the model predictive control algorithm which guarantee the closed loop stability. Finally, the proposed method is applied to a numerical example in order to show the effectiveness of our results.

• Parasites, Hosts and Diseases
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• v.54 no.1
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• pp.39-46
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• 2016

Theileria annulata is a tick-borne intracellular protozoan parasite that causes tropical theileriosis, a fatal bovine lymphoproliferative disease. The parasite predominantly invades bovine B lymphocytes and macrophages and induces host cell transformation by a mechanism that is not fully comprehended. Analysis of signaling pathways by quantitative real-time PCR (qPCR) could be a highly efficient means to understand this transformation mechanism. However, accurate analysis of qPCR data relies on selection of appropriate reference genes for normalization, yet few papers on T. annulata contain evidence of reference gene validation. We therefore used the geNorm and NormFinder programs to evaluate the stability of 5 candidate reference genes; 18S rRNA, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), ACTB (${\beta}-actin$), PRKG1 (protein kinase cGMP-dependent, type I) and TATA box binding protein (TBP). The results showed that 18S rRNA was the reference gene most stably expressed in bovine PBMCs transformed and non-transformed with T. annulata, followed by GAPDH and TBP. While 18S rRNA and GAPDH were the best combination, these 2 genes were chosen as references to study signaling pathways involved in the transformation mechanism of T. annulata.

• The Korean Journal of Physiology
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• v.25 no.2
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• pp.125-131
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• 1991

Inactivation properties of Ca current in the unfertilized eggs of mouse were studied by using the whole cell voltage clamp technique and single microelectrode voltage clamp technique. Membrane potential was held at -80 mV and step depolarization was applied from -50 mV to 50 mV for $200{\sim}500\;ms$. Peak of inward Ca currents was $-2{\sim}-4\;nA$ at a membrane Potentials from -20 mV to 0 mV and outward currents were not observed within the membrane voltage range studied $(-50{\sim}50\;mV)$. Inward currents were fully inactivated within 200 ms after the onset of step depolarization. As the membrane became depolarized, time constant of inactivation (${\tau}$) was decreased but remained around $20{\sim}30\;ms$ beyond 10 mV. When $Ca^{2+}$ was used as a charge earlier, inactivation of inward $Ca^{2+}$ current also occured and time course of inactivation was similar to that of $Ca^{2+}$ currents as charge carrier. In the bathing solution containing high potassium $(131\;mM\;K^+)$, process of inactivation was not changed except a parallel decrease of value for the entire range of membrane potential. Steady-state inactivation of the $current(h_{\infty})$ obtained from the double pulse experiment showed the voltage-dependent change. These results suggested that inactivation of Ca currents in the unfertilized eggs of mouse was voltage-dependent.

• Wind and Structures
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• v.27 no.6
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• pp.381-397
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• 2018

Nonlinear behavior in fluid-structure interaction (FSI) of bridge decks becomes increasingly significant for modern bridges with increasing spans, larger flexibility and new aerodynamic deck configurations. Better understanding of the nonlinear aeroelasticity of bridge decks and further development of reduced-order nonlinear models for the aeroelastic forces become necessary. In this paper, the amplitude-dependent and neutral angle dependent nonlinearities of the motion-induced loads are further highlighted by series of computational fluid dynamics (CFD) simulations. An effort has been made to investigate a semi-analytical time-domain model of the nonlinear motion induced loads on the deck, which enables nonlinear time domain simulations of the aeroelastic responses of the bridge deck. First, the computational schemes used here are validated through theoretically well-known cases. Then, static aerodynamic coefficients of the Great Belt East Bridge (GBEB) cross section are evaluated at various angles of attack, leading to the so-called nonlinear backbone curves. Flutter derivatives of the bridge are identified by CFD simulations using forced harmonic motion of the cross-section with various frequencies. By varying the amplitude of the forced motion, it is observed that the identified flutter derivatives are amplitude-dependent, especially for $A^*_2$ and $H^*_2$ parameters. Another nonlinear feature is observed from the change of hysteresis loop (between angle of attack and lift/moment) when the neutral angles of the cross-section are changed. Based on the CFD results, a semi-analytical time-domain model for describing the nonlinear motion-induced loads is proposed and calibrated. This model is based on accounting for the delay effect with respect to the nonlinear backbone curve and is established in the state-space form. Reasonable agreement between the results from the semi-analytical model and CFD demonstrates the potential application of the proposed model for nonlinear aeroelastic analysis of bridge decks.

• Advances in nano research
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• v.10 no.3
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• pp.253-261
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• 2021

Polydimethylsiloxane (PDMS) is one of the most widely adopted silicon-based organic polymeric elastomers. Elastomeric nanostructures are normally required to accomplish an explicit mechanical role and correspondingly their mechanical properties are crucial to affect device and material performance. Despite its wide application, the mechanical properties of PDMS are yet fully understood. In particular, the time dependent mechanical response of PDMS has not been fully elucidated. Here, utilizing state-of-the-art PeakForce Quantitative Nanomechanical Mapping (PFQNM) together with Force Volume (FV) and Fast Force Volume (FFV), the elastic moduli of PDMS samples were assessed in a time-dependent fashion. Specifically, the acquisition frequency was discretely changed four orders of magnitude from 0.1 Hz up to 2 kHz. Careful calibrations were done. Force data were fitted with a linearized DMT contact mechanics model considering surface adhesion force. Increased Young's modulus was discovered with increasing acquisition frequency. It was measured 878 ± 274 kPa at 0.1 Hz and increased to 4586 ± 758 kPa at 2 kHz. The robust local probing of mechanical measurement as well as unprecedented high-resolution topography imaging open new avenues for quantitative nanomechanical mapping of soft polymers, and can be extended to soft biological systems.

• Structural Engineering and Mechanics
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• v.77 no.2
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• pp.197-215
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• 2021

Under a severe environment of multiple hazards such as earthquakes and winds, the life-cycle performance of engineering structures may inevitably be deteriorated due to the fatigue effect caused by long-term exposure to wind loads, which would further increase the structural vulnerability to earthquakes. This paper presents a framework for evaluating the lifetime structural seismic performance under the effect of wind-induced fatigue considering different sources of uncertainties. The seismic behavior of a high-rise steel-concrete composite frame with buckling-restrained braces (FBRB) during its service life is systematically investigated using the proposed approach. Recorded field data for the wind hazard of Fuzhou, Fujian Province of China from Jan. 1, 1980 to Mar. 31, 2019 is collected, based on which the distribution of wind velocity is constructed by the Gumbel model after comparisons. The OpenSees platform is employed to establish the numerical model of the FBRB and conduct subsequent numerical computations. Allowed for the uncertainties caused by the wind generation and structural modeling, the final annual fatigue damage takes the average of 50 groups of simulations. The lifetime structural performance assessments, including static pushover analyses, nonlinear dynamic time history analyses and fragility analyses, are conducted on the time-dependent finite element (FE) models which are modified in lines with the material deterioration models. The results indicate that the structural performance tends to degrade over time under the effect of fatigue, while the influencing degree of fatigue varies with the duration time of fatigue process and seismic intensity. The impact of wind-induced fatigue on structural responses and fragilities are explicitly quantified and discussed in details.

• Journal of Korean Society of Transportation
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• v.27 no.6
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• pp.129-137
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• 2009

Operation of intelligent transport systems technologies in transportation networks and more detailed analysis give rise to necessity of dynamic traffic analysis model. Existing static models describe network state in average. on the contrary, dynamic traffic analysis model can describe the time-dependent network state. In this study, a dynamic traffic model for the expressway system using FTMS data is developed. Time-dependent origin-destination trip tables for nationwide expressway network are constructed using TCS data. Computation complexity is critical issue in modeling nationwide network for dynamic simulation. A subarea analysis model is developed which converts the nationwide O-D trip tables into subarea O-D trip tables. The applicability of the proposed model is tested under various scenario. This study can be viewed as a starting point of developing deployable dynamic traffic analysis model. The proposed model needs to be expanded to include arterial as well without critical computation burden.