• Radiation Oncology Journal
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• v.34 no.1
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• pp.34-44
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• 2016

Purpose: A prospective phase II trial was conducted to evaluate the effectiveness and toxicity of regional hyperthermia and whole liver irradiation (WLI) for numerous chemorefractory liver metastases from colorectal cancer. Materials and Methods: Enrolled patients had numerous chemorefractory hepatic metastases from colorectal cancer. Five sessions of hyperthermia and seven fractions of 3-gray WLI were planned. Health-related quality of life (HRQoL) was determined using the Korean version of the European Organization for Research and Treatment of Cancer quality of life questionnaire C-30 and the Functional Assessment of Cancer Therapy-Hepatobiliary version 4.0. Objective and pain response was evaluated. Results: A total of 12 patients consented to the study and the 10 who received WLI and hyperthermia were analyzed. WLI was completed as planned in nine patients and hyperthermia in eight. Pain response was partial in four patients and stable in four. Partial objective response was achieved in three patients (30.0%) and stable disease was seen in four patients at the 1-month follow-up. One patient died 1 month after treatment because of respiratory failure related to pleural metastasis progression. Other grade III or higher toxicities were detected in three patients; however, all severe toxicities were related to disease progression rather than treatment. No significant difference in HRQoL was noted at the time of assessment for patients who were available for questionnaires. Conclusion: Combined WLI and hyperthermia were well tolerated without severe treatment-related toxicity with a promising response from numerous chemorefractory hepatic metastases from colorectal cancer.

• Journal of Veterinary Clinics
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• v.31 no.6
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• pp.523-526
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• 2014

Three dogs were admitted for repair of bone fracture. Case 1 (Maltese, 1.8 kg, intact female, 5-month-old) and case 2 (poodle, 3.0 kg, intact female, 6-month-old) had non-weight bearing lameness in the left pelvic limb, and case 3 (mixed, 3.3 kg, intact female, age unknown) had non-weight-bearing lameness in the left thoracic limb. On orthopedic examination, there was pain, crepitus, palpable instability and substantial soft tissue swelling on the affected side. No neurological deficits were identified. Radiographs revealed left proximal metaphyseal tibial and fibular fractures in cases 1 and 2, and left proximal metaphyseal radial and ulnar fractures in case 3. All cases had closed long-bone fractures with short juxta-articular fracture segments. Under fluoroscopic guidance, proper placement of the ring fixation elements was confirmed during surgery. Two or three rings were used to stabilize fractures with traditional circular external skeletal fixators (CESF). Postoperative radiographs showed acceptable alignment and apposition of the previously identified fracture. Time to radiographic union ranged from 5 to 14 weeks and there were no signs of implant failure or pin tract infection. Functional outcomes were excellent in all cases. CESF can be successfully used to reduce short juxta-articular fractures in which bone plates or external skeletal fixation cannot be applied.

• Journal of Broadcast Engineering
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• v.26 no.4
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• pp.409-418
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• 2021

Conformal coating is a technology that protects PCB(Printed Circuit Board) and minimizes PCB failures. Since the defects in the coating are linked to failure of the PCB, the coating surface is examined for air bubbles to satisfy the successful conditions of the conformal coating. In this paper, we propose an algorithm for detecting problematic bubbles in high-risk groups by applying image signal processing. The algorithm consists of finding candidates for problematic bubbles and verifying candidates. Bubbles do not appear in visible light images, but can be visually distinguished from UV(Ultra Violet) light sources. In particular the center of the problematic bubble is dark in brightness and the border is high in brightness. In the paper, these brightness characteristics are called valley and mountain features, and the areas where both characteristics appear at the same time are candidates for problematic bubbles. However, it is necessary to verify candidates because there may be candidates who are not bubbles. In the candidate verification phase, we used convolutional neural network models, and ResNet performed best compared to other models. The algorithms presented in this paper showed the performance of precision 0.805, recall 0.763, and f1-score 0.767, and these results show sufficient potential for bubble test automation.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.41 no.3
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• pp.305-316
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• 2021

Construction accidents occur due to a number of reasons-worker carelessness, non-adoption of safety equipment, and failure to comply with safety rules are some examples. Because much construction work is done outdoors, weather conditions can also be a factor in accidents. Past construction accident data are useful for accident prevention, but since construction accident data are often in a text format consisting of natural language, extracting construction hazards from construction accident data can take a lot of time and that entails extra cost. Therefore, in this study, we extracted construction hazards from 2,026 domestic construction accident reports using text mining and performed a seasonal analysis of construction hazards through frequency analysis and centrality analysis. Of the 254 construction hazards defined by Korea's Ministry of Land, Infrastructure, and Transport, we extracted 51 risk factors from the construction accident data. The results showed that a significant hazard was "Formwork" in spring and autumn, "Scaffold" in summer, and "Crane" in winter. The proposed method would enable construction safety managers to prepare better safety measures against outdoor construction accidents according to weather, season, and climate.

• Journal of Dental Rehabilitation and Applied Science
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• v.36 no.4
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• pp.262-271
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• 2020

To restore a tooth with a fracture line extending below the marginal bone level, a surgical crown lengthening procedure accompanied by ostectomy could be considered to expose the fracture line and reestablish the biologic width. However, this procedure could lead to esthetic failure, especially in the anterior teeth. Therefore, orthodontic extrusion, which elevates the fracture line from within the alveolar socket without sacrificing the supporting bone and gingiva, is recommended. This technique allows for the proper placement of the crown on a sound tooth structure, with the reestablishment of the biologic width. Alternatively, surgical extrusion is an one-step procedure that is simpler and less time-consuming than orthodontic extrusion; placing and adjusting the orthodontic appliance does not require multiple visits. This study presents successful restoration in 2 cases with a crown-tooth root fracture of the maxillary central incisor treated using a multidisciplinary approach through orthodontic extrusion or surgical extrusion followed by successful restoration.

• Nuclear Engineering and Technology
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• v.17 no.3
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• pp.211-215
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• 1985

The effects of temperature and strain rate on the I-SCC behaviors of Zircaloy-4 were investigated by constant load test at 30$0^{\circ}C$ and constant elongation rate test at 300, 350 and 40$0^{\circ}C$ in 3.34mg $I_2$/㎤. The results showed that I-SCC susceptibility increased as the strain rate decreased or the temperature increased. The empirical relation between the stress and the time to failure at 30$0^{\circ}C$ was given by 1/ $t_{f}$∝exp (0.3$\sigma$/$\sigma$$_{UTS}$-31.5) When the I-SCC susceptibility was expressed by the ratio of fracture energy in iodine atmosphere to that in the inert atmosphere, severe I-SCC susceptibility was found near 7.6$\times$10$^{-6}$ sec at 30$0^{\circ}C$ and the maximum point of I-SCC susceptibility tended to shift to the higher strain rate with increasing the temperature. The quasi-cleavage fracture was observed in I-SCC fracture surface. From these results, it was certain that the film repture step was involved as an important process in the I-SCC mechanism of Zircaloy-4.4.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.2D
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• pp.243-248
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• 2008

Moisture damage of asphalt pavements can usually occur because of the loss of adhesion and cohesion between the asphalt binder and aggregate in the asphalt mixture due to presence of water. And this is one of the causes that is effect on the main distress of asphalt pavement. The objective of this study is to find out moisture damage characteristics of asphalt pavement. Effects of this study changes of the material properties and resistance characteristics of moisture damage on the asphalt mixtures under various temperatures and repeated immersion using indirect tensile test and modify Lottman test were evaluated during this study. The asphalt mixtures were produced using straight asphalt binder, SBS modified asphalt binder and aggregates. The material properties (resilient modulus, indirect tensile strength, failure energy and $DCSE_f$) of the asphalt mixtures were generally decreased with increasing to moisture damage caused by the number of repeated immersion. The decrease ratios of material properties by repeated immersion on SBS modified asphalt mixtures were lower than those of straight asphalt mixtures at all three test temperatures. As a conclusion, current criterion for evaluation moisture damage of asphalt mixtures is difficult for using distinction standard because of the limited evaluation criterion with one time immersion and single material property. Based on this research, to evaluate long term moisture damage on asphalt mixtures, material property tests of various kinds with repeated immersion test are considered.

• Clinics in Shoulder and Elbow
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• v.26 no.3
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• pp.231-237
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• 2023

Background: In the past decade, the number of anatomic total shoulder arthroplasty (aTSA) procedures has steadily increased. Patients over 65 years of age comprise the vast majority of recipients, and outcomes have been well documented; however, patients are opting for definitive surgical treatment at younger ages.We aim to report on the effects of age on the long-term clinical outcomes following aTSA. Methods: Among the patients who underwent TSA, 119 shoulders were retrospectively analyzed. Preoperative and postoperative clinical outcome data were collected. Linear regression analysis (univariate and multivariate) was conducted to evaluate the associations of clinical outcomes with age. Kaplan-Meier curves and Cox regression analyses were performed to evaluate implant survival. Results: At final follow-up, patients of all ages undergoing aTSA experienced significant and sustained improvements in all primary outcome measures compared with preoperative values. Based on multivariate analysis, age at the time of surgery was a significant predictor of postoperative outcomes. Excellent implant survival was observed over the course of this study, and Cox regression survival analysis indicated age and sex to not be associated with an increased risk of implant failure. Conclusions: When controlling for sex and follow-up duration, older age was associated with significantly better patient-reported outcome measures. Despite this difference, we noted no significant effects on range of motion or implant survival. Level of evidence: IV.

• Radiation Oncology Journal
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• v.16 no.4
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• pp.409-423
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• 1998

Purpose : This retrospective study was tried to evaluate the clinical characteristics of patients, patterns of failure, survival rates, prognostic factors affecting survival, and treatment related toxicities when non-small cell lung cancer patients was treated by definitive radiotherapy alone or combined with chemotherapy. Materials and Methods : We evaluated the treatment results of 70 patients who were treated by definitive radiation therapy for non-small cell lung cancer at the Department of Radiation Oncology, Ewha Womans University Hospital, between March 1982 and April 1996. The number of patients of each stage was 2 in stage I, 6 in stage II, 30 in stage III-A, 29 in stage III-B, 3 in stage IV. Radiation therapy was administered by 6 MV linear accelerator and daily dose was 1.8-2.0 Gy and total radiation dose was ranged from 50.4 Gy to 72.0 Gy with median dose 59.4 Gy. Thirty four patients was treated with combined therapy with neoadjuvant or concurrent chemotherapy and radiotherapy, and most of them were administered with the multi-drug combined chemotherapy including etoposide and cisplatin. The survival rate was calculated with the Kaplan-Meier methods. Results : The overall 1-year, 2-year, and 3-year survival rates were 63$\%$, 29$\%$, and 26$\%$, respectively. The median survival time of all patients was 17 months. The disease-free survival rate for 1-year and 2-year were 23$\%$ and 16$\%$, respectively. The overall 1-year survival rates according to the stage was 100$\%$ for stage I, 80$\%$ for stage II, 61$\%$ for stage III, and 50$\%$ for stage IV. The overall 1-year 2-year, and 3-year survival rates for stage III patients only were 61$\%$, 23$\%$, and 20$\%$, respectively. The median survival time of stage III patients only was 15 months. The complete response rates by radiation therapy was 10$\%$ and partial response rate was 50$\%$. Thirty patients (43$\%$) among 70 patients assessed local control at initial 3 months follow-up duration. Twenty four (80$\%$) of these 30 Patients was possible to evaluate the pattern of failure after achievement of local control. And then, treatment failure occured in 14 patients (58$\%$): local relapse in 6 patients (43$\%$), distant metastasis in 6 patients (43$\%$) and local relapse with distant metastasis in 2 patients (14$\%$). Therefore, 10 patients (23$\%$) were controlled of disease of primary site with or without distant metastases. Twenty three patients (46$\%$) among 50 patients who were possible to follow-up had distant metastasis. The overall 1-year survival rate according to the treatment modalities was 59$\%$ in radiotherapy alone and 66$\%$ in chemoirradiation group. The overall 1-year survival rates for stage III patients only was 51$\%$ in radiotherapy alone and 68$\%$ in chemoirradiation group which was significant different. The significant prognostic factors affecting survival rate were the stage and the achievement of local control for all patients at univariate- analysis. Use of neoadjuvant or concurrent chemotherapy, use of chemotherapy and the achievement of local control for stage III patients only were also prognostic factors. The stage, pretreatment performance status, use of neoadjuvant or concurrent chemotherapy, total radiation dose and the achievement of local control were significant at multivariate analysis. The treatment-related toxicities were esophagitis, radiation pneunonitis, hematologic toxicity and dermatitis, which were spontaneously improved, but 2 patients were died with radiation pneumonitis. Conclusion : The conventional radiation therapy was not sufficient therapy for achievement of long-term survival in locally advanced non-small cell lung cancer. Therefore, aggressive treatment including the addition of appropriate chemotherapeutic drug to decrease distant metastasis and preoperative radiotherapy combined with surgery, hyperfractionation radiotherapy or 3-D conformal radiation therapy for increase local control are needed.

• Tuberculosis and Respiratory Diseases
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• v.48 no.5
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• pp.766-772
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• 2000

Background : Pressure rise time (PRT) is the time in which the ventilator aclieves the set airway pressure in pressure-targeted modes, such as pressure control ventilation (PCV). With varying PRT, in principle, the peak inspiratory flow rate of the ventilator also varies. And if PRT is set to a shorter duration, the effective duration of target pressure level would be prolonged, which in turn would increase inspiratory tidal volume(Vti) and mean airway pressure (Pmean). We also postulated that the increase in Vti with shortening of PRT may relate inversely to the patients' basal airway resistance. Methods : In 13 paralyzed patients on PCV (pressure control 18$\pm$9.5 cm $H_2O$ $FIO_2\;0.6\pm0.3$, PEEP 5$\pm$3 cm $H_2O$, f 20/min, I : E1 : 2) with Servo 300 (Siemens-Elema, Solna, Sweden) from various causes of respiratory failure, PRT of 10 %, 5 % and 0 % were randomly applied. At 30 min of each PRT trial, peak inspiratory flow (PIF, L/sec), Vti (ml), Pmean (cm $H_2O$) and ABGA were determined. Results : At PRT 10%, 5%, and 0%, PIF were 0.69$\pm$0.13, 0.77$\pm$0.19, 0.83$\pm$0.22, respectively (p<0.001). Vti were 425$\pm$94, 439$\pm$101, 456$\pm$106, respectively (p<0.001), and Pmean were 11.2$\pm$3.7, 12.0$\pm$3.7, 12.5$\pm$3.8, respectively (p<0.001). pH were 7.40$\pm$0.08, 7.40$\pm$0.92, 7.41$\pm$0.96, respectively (p=0.00) ; $PaCO_2$ (mm Hg) were 47.4$\pm$15.8, 47.2 $\pm$15.7, 44.6$\pm$16.2, respectively (p=0.004) ; $PAO_2-PaO_2$ (mm Hg) were 220$\pm$98, 224$\pm$95, 227$\pm$94, respectively (p=0.004) ; and $V_n/V_T$ as determined by ($PaCO_2-P_E-CO_2$)/$PaCO_2$ were 0.67$\pm$0.07, 0.67$\pm$0.08, 0.66$\pm$0.08, respectively (p=0.007). The correlation between airway resistance and change of Vti from PRT 10% to 0% were r= -0.243 (p=0.498). Conclusion : Shortening of pressure rise timee during PCV was associated with increased tidal volume, increased mean airway pressure and lower $PaCO_2$.