• Biomolecules & Therapeutics
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• v.9 no.4
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• pp.258-262
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• 2001

In the advanced age, cardiovascular disease is more serious than any other disease. Especially, the thrombus causes the serious disease like apoplexia, carebri and myocardial infarction. Thrombosis is caused by the injury of endothelium and the alterations in normal blood flow. To investigate activities of Carthamus tinctorius L. Semen butanol fraction for blood coagulation system, endotoxin (4000EU/kg) was injected (i..v) to rats at 1hr after administration of Carthamus tinctorius L. Semen butanole fraction (500 mg/kg, p.o.). Carthamus tinctorius L. Semen butanol fraction was found to have antiplatelet activity in vitro. In vivo it showed a delay of blood clotting time, and prothrombin time, and reduction of fibrinogen and FDP It also increased SOD activity, and decreased MDA content. These results suggest that the antithrombosis effect of Carthamus tinctorius L. Semen butanol frac tion results from suppressive activity for a blood coagulation system and antioxidative activity.

• Journal of the Ergonomics Society of Korea
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• v.30 no.2
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• pp.365-373
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• 2011

The existing GOMS model overestimates the performance time of mouse activities because it describes them in a serial sequence. However, parallel movements of eye and hand(eye-hand coordination) have been dominant in mouse activities and this eye-hand coordination is the main factor for the overestimation of performance time. In this study, therefore, the revised CGOMSL model was developed to implement eye-hand coordination to the mouse activity to overcome one of the limitations of GOMS model, the lack of capability for parallel processing. The suggested revised CGOMSL model for drag activity, as an example for one of mouse activities in this study, begins visual search processing before a hand movement but ends the visual search processing with the hand movement in the same time. The results show that the revised CGOMSL model made the prediction of human performance more accurately than the existing GOMS model. In other words, one of the limitations of GOMS model, the incapability of parallel processing, could be overcome with the revised CGOMSL model so that the performance time should be more accurately predicted.

• Korean Journal of Child Studies
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• v.33 no.4
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• pp.19-34
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• 2012

This study investigated the differences in time use patterns and psychological states across daily activity contexts and interpersonal contexts, depending on the levels of school maladjustment among elementary school students. Using the Experience Sampling Method (ESM), 107 elementary school 6th grade students' daily time use patterns and psychological states across daily contexts were measured six times a day over a period of 4 days. Using the school maladjustment scale, an internal problem based school maladjusted group and an external problem based school maladjusted group were identified and selected. The daily time use patterns and psychological states of both school maladjusted groups were compared to those of the adjusted groups. The principle findings are as follows: first, the school maladjusted group students' daily time use patterns across daily activity contexts or interpersonal contexts did not differ from those of the students from the school adjusted group. Second, the school maladjusted group students experienced more negative emotions, lower concentration levels, and lower motivation levels across daily contexts than the school adjusted group students. These differences in motivation between the external problem school maladjusted group and adjusted group, however, were greater in the schoolwork context compared to the other daily activity contexts. The findings were discussed in the contexts of the daily experiences of child school maladjustment.

• Archives of Pharmacal Research
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• v.28 no.6
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• pp.667-674
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• 2005

The leaves of Persimmon (Diospyros kaki L.) has long been used for tea in Korea since it was thought to be effective against hypertension. An anticoagulant fraction was purified through gel filtration G-100, hydrophobic, gel filtration G-150, and FPLC, Phenyl superpose column chromatographies. The purified fraction was homogenous and its Mr was estimated 10,000 Da by gel filtration and SDS-PAGE. The purified fraction was sensitive to treatment of subtilisin B, but not to heat and its activity was not changed after periodate oxidation, indicating that the activity was not due to carbohydrates. It delayed thrombin time (TT), activated partial thromboplastin time (APTT), and prothrombin time (PT) using human plasma. TT was more sensitive than APTT and PT, suggesting that the anticoagulant activity may be caused by a degradation or a defect of fibrin or thrombin. It did not cause the hydrolysis of fibrin after incubation. However, it inhibited thrombin-catalyzed fibrin formation with a competitive inhibition pattern. These results indicate that it may be an antithrombotic agent and that it is bound to fibrinogen binding sites of thrombin.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.3
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• pp.1189-1204
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• 2018

Detecting and capturing 3D human structures from the intensity-based image sequences is an inherently arguable problem, which attracted attention of several researchers especially in real-time activity recognition (Real-AR). These Real-AR systems have been significantly enhanced by using depth intensity sensors that gives maximum information, in spite of the fact that conventional Real-AR systems are using RGB video sensors. This study proposed a depth-based routine-logging Real-AR system to identify the daily human activity routines and to make these surroundings an intelligent living space. Our real-time routine-logging Real-AR system is categorized into two categories. The data collection with the use of a depth camera, feature extraction based on joint information and training/recognition of each activity. In-addition, the recognition mechanism locates, and pinpoints the learned activities and induces routine-logs. The evaluation applied on the depth datasets (self-annotated and MSRAction3D datasets) demonstrated that proposed system can achieve better recognition rates and robust as compare to state-of-the-art methods. Our Real-AR should be feasibly accessible and permanently used in behavior monitoring applications, humanoid-robot systems and e-medical therapy systems.

• Physical Therapy Korea
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• v.9 no.2
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• pp.33-42
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• 2002

The purpose of this study was to compare the onset times of muscle activities and the order of muscle firing in hamstring gluteus maximus, and lumbar erector spinae muscle during active hip extension between subjects with low back pain (LBP) and healthy subjects. Thirty subjects, 15 with LBP and 15 healthy subjects, participated in this study. Electromyographic activity was recorded during active hip extension in prone and standing position. Relative onset times of these muscle activities were determined. Similar muscle firing order in hamstring, gluteus maximus, and lumbar erector spinae muscle showed in both groups and positions. However, the onset time of gluteus maximus was significantly later in prone and standing active hip extension in subjects with LBP than in healthy subjects. The onset time of lumber erector spinae muscle activity was significantly delayed in subjects with LBP in standing active hip extension, The delayed onset times of gluteus maximus and lumbar erector spinae muscles' activities were probably related to LBP. Further studies are needed to identify whether the delayed onset times of gluteus maximus and lumbar erector spinae muscle activities are the contributing factors to LBP.

• The korean journal of orthodontics
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• v.24 no.1 s.44
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• pp.105-114
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• 1994

The movement of teeth during orthodontic treatment requires bone remodeling process of bone formation and bone resolution. To find out the changes occuring in the cell itself, mechanical stress was applied to the cell populations involved in the bone metabolism. Bone tissue cell populations were isolated from fetal rat calvaria and divided into OC and OB groups. Following results were obtained from measuring the changes in acid & alkaline phosphatease activity, cyclic AMP and $PGE_2$ production in time lapse after the application of mechanical stress. 1. In case of the marker enzyme of specific bone tissue cell, acid phosphatase activity was high in OC group and alkaline phosphatase activity was high in OB group. 2. After the mechanical stress was applied, acid phosphatase activity was decreased in both OC and OB groups and alkaline phosphatase activity was increase in OB group. 3. When the mechanical stress was applied for 15, 30 and 60 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased. 4. When the mechanical stress was applied for 20 and 40 minutes, the production of $PGE_2$ increased in both OC and OB groups, as the time span increased.

• Journal of Korean Academy of Nursing Administration
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• v.9 no.1
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• pp.5-18
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• 2003

Purpose : For improvement of nursing services in ambulatory unit, ambulatory nursing activity was identified and the required time by nursing activity was measured. Method : The data were collected from 4 tertiary hospitals and 2 secondary hospitals. The method of data collection was used the self-reporting method. The 123 nurse-work days and 137 nurse-aid-work days in 6 hospitals were analyzed. Results : As a result, 11 ambulatory nursing domains and 79 ambulatory nursing activities were confirmed. Above 50% of subjects performed the general outpatient affair domain. The percentage of total time spent in each domain were as follows : general outpatient affair domain, 58.3%, patient education ${\cdot}$ counseling domain, 10.8%, therapeutic care domain, 8.6% and so on. And the average hours were measured by activity and domain. Conclusion : For the improvement of ambulatory nursing care, the strategies that keep the legal standard of number of ambulatory nurse and exchange the nursing-aid for the nurse is needed. And it is also needed to standardize the ambulatory nursing services.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.30 no.2
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• pp.44-50
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• 2007

This paper deals with the problem of scheduling jobs and rate-modifying activities on parallel machines. A rate-modifying activity is an activity that changes the production rate of equipment such as maintenance and readjustment. If a job is scheduled after the rate-modifying activity, then the processing time varies depending on the modifying rate of the activity. In this study, we extend the single machine problem to parallel machines problem and propose algorithms is to schedule the rate-modifying activities and jobs to minimize the makespan on parallel machines which is NP-hard. We propose a branch and bound algorithm with three lower bounds to solve medium size problems optimally. Also we develop three heuristics, Modified Longest Processing Time, Modified MULTIFIT and Modified COMBINE algorithms to solve large size problems. The test results show that branch and bound algorithm finds the optimal solution in a reasonable time for medium size problems (up to 15 jobs and 5 machines). For large size problem, Modified COMBINE and Modified MULTIFIT algorithms outperform Modified LPT algorithm in terms of solution quality.

• Journal of Physiology & Pathology in Korean Medicine
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• v.21 no.2
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• pp.528-531
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• 2007

Artemisia vulgaris essential oil exhibited a strong metal chelating activity but withlow reducing power, and radical scavenging activity. However, a gradual increase in the radical scavenging activity was obtained with increasing concentration and reaction time.