• Geomechanics and Engineering
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• 제16권4호
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• pp.363-373
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• 2018

The evaluation of Thermo-Hydro-Mechanical (THM) coupling behavior is important for the development of underground space for various purposes. For a high-level radioactive waste repository excavated in a deep underground rock mass, the accurate prediction of the complex THM behavior is essential for the long-term safety and stability assessment. In order to develop reliable THM analysis techniques effectively, an international cooperation project, Development of Coupled models and their Validation against Experiments (DECOVALEX), was carried out. In DECOVALEX-2015 Task B2, the in situ THM experiment that was conducted at Horonobe Underground Research Laboratory(URL) by Japan Atomic Energy Agency (JAEA), was modeled by the research teams from the participating countries. In this study, a THM coupling technique that combined TOUGH2 and FLAC3D was developed and applied to the THM analysis for the in situ experiment, in which rock, buffer, backfill, sand, and heater were installed. With the assistance of an artificial neural network, the boundary conditions for the experiment could be adequately implemented in the modeling. The thermal, hydraulic, and mechanical results from the modeling were compared with the measurements from the in situ THM experiment. The predicted buffer temperature from the THM modelling was about $10^{\circ}C$ higher than measurement near by the overpack. At the other locations far from the overpack, modelling predicted slightly lower temperature than measurement. Even though the magnitude of pressure from the modeling was different from the measurements, the general trends of the variation with time were found to be similar.

• 한국지반공학회논문집
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• 제27권11호
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• pp.55-69
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• 2011

다양한 지반공학적 문제들에서 불포화 상태의 중요성이 강조되면서, 불포화 지반의 열-수리-역학적 현상들에 대한 거동특성을 모사하기 위한 역학적 구성모델 개발이 진행되고 있다. 본 연구에서는 Bishop의 유효응력 정의에 근거한 불포화 지반의 역학적 탄소성 구성모델을 제시하였다. 유효응력에 근거한 구성관계는 유효응력과 온도를 주 변수로 증분 형식으로 표현되었으며, 이를 이용하여 응력 갱신과 강성 텐서를 산정하였다. 개발된 구성모델을 이용하여 THM 현상을 포함하는 불포화토의 1차원 거동, 불포화토의 삼축 압축시험, 그리고 고준위 방사성폐기물 시설의 완충재의 거동 특성에 관한 예제 해석을 수행하여 해의 안정성과 구성모델의 적용성에 대하여 논의하였다. 수치해석결과는 개발된 역학적 구성모델이 THM 현상의 매우 복잡한 거동을 효과적으로 모사할 수 있었으며, 일반적인 불포화토의 거동 해석뿐만 아니라 다양한 환경 조건하에서의 THM 거동 해석에 적용이 가능할 것으로 판단된다.

• 한국지반공학회논문집
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• 제27권3호
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• pp.75-83
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• 2011

일반적인 불포화지반의 거동뿐만 아니라, 열과 관련된 분야, 지반환경 분야 등 다양한 분야에서 불포화 다공질 재료의 열적-수리적-역학적으로 결합된 문제들이 대두되면서 이러한 문제들을 해석하기 위한 수치도구 개발의 필요성이 대두되고 있다. 본 논문에서는 거시적 접근법(macroscopic approach)에 근거하여 불포화지반에 대한 열-수리-역학거동의 수식화를 하였다. 흙, 물, 공기에 대한 질량보존의 법칙, 에너지 보존법칙, 그리고 하중평형 조건식으로부터 결합된(coupled) 4개의 지배방정식을 유도하였다. Galerkin 간략화와 시간적분으로부터 주 변수인 변위(u), 가스압($P_g$), 유체압($P_1$), 온도(T)를 Newton의 반복과정을 이용하여 구하는 유한요소 프로그램(FEM)을 작성하였다. 개발된 프로그램을 이용하여 다공질재료에서 2상 흐름 문제 중 일차원 배수실험(u-$P_g-P_1$), 온도 압밀(u-$P_1$-T), 그리고 지표면 온도변화에 의한 말뚝의 주변지반에 대한 영향(u-$P_1$-T)에 대하여 수치해석을 수행하고 논의하였다.

• Macromolecular Research
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• 제16권6호
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• pp.517-523
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• 2008

A RGD (Arg-Gly-Asp) conjugated chitosan hydrogel was used as a cell-supporting scaffold for articular cartilage regeneration. Thermosensitive chitosan-Pluronic (CP) has potential biomedical applications on account of its biocompatibility and injectability. A RGD-conjugated CP (RGD-CP) copolymer was prepared by coupling the carboxyl group in the peptide with the residual amine group in the CP copolymer. The chemical structure of RGD-CP was characterized by $^1H$ NMR and FT IR. The concentration of conjugated RGD was quantified by amino acid analysis (AAA) and rheology of the RGD-CP hydrogel was investigated. The amount of bound RGD was $0.135{\mu}g$ per 1 mg of CP copolymer. The viscoelastic parameters of RGD-CP hydrogel showed thermo-sensitivity and suitable mechanical strength at body temperature for cell scaffolds (a> 100 kPa storage modulus). The viability of the bovine chondrocyte and the amount of synthesized glycosaminoglycans (GAGs) on the RGD-CP hydrogels were evaluated together with the alginate hydrogels as a control over a 14 day period. Both results showed that the RGD-CP hydrogel was superior to the alginate hydrogel. These results show that conjugating RGD to CP hydro gels improves cell viability and proliferation, including extra cellular matrix (ECM) expression. Therefore, RGD conjugated CP hydrogels are quite suitable for a chondrocyte culture and have potential applications to the tissue engineering of articular cartilage tissue.