• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.8 no.2
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• pp.57-66
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• 2013

Objectives : The present study examines indications and treatment techniques of Chuna manual therapy. Methods : We searched the clinical studies on Chuna manual therapy through 5 korean web databases, 2 journals.(key word 'chuna') After selecting appropriate clinical studies(Bongchuna, massage, side effect, contraindication are excepted), we analyzed them according to diseases, Chuna techniques, type of clinical trials. Results : 101 studies are selected and analyzed. They studied about cervical(26%), thoracic(12%), lumbar (29%)spinal disorders, temporomandibular joint disorders(4%), pelvic region disorders(4%), upper(6%), lower extremity(5%) disorders and other diseases(15%). Spinal disorders are studied frequently. Mild techniques like supine position both hand cervical spine flexion distraction, JS supine position cervical spine distraction, flexion distraction technique are used more frequently than adjustment by thrust. Conclusions : We have to enhance education and training about techniques that are frequently used and studied. Research and improvement of infrequently used techniques are needed. In-depth research about side effects and contraindication is needed. Highquality clinical research and systematic review should be needed to prove the therapeutic effect of Chuna treatment.

• Journal of TMJ Balancing Medicine
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• v.8 no.1
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• pp.16-23
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• 2018

Positional Release Techniques (PRTs) are an umbrella term for manual therapies harnessing spontaneous musculoskeletal balancing mechanism of the body facilitated by finding and maintaining therapeutic position. PRT has its origin in the Strain Counterstrain (SCS) technique by Dr. Jones but encompasses diverse related techniques that stemmed off from the SCS. PRT emphasizes postural balance within the body and innate healing potential of the body including the postural balance of the temporomandibular joint (TMJ). This study briefly reviews concepts, history, and contemporary study reports on PRT with a focus on the yin-yang balance based approach of PRT.

• Molecules and Cells
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• v.46 no.2
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• pp.99-105
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• 2023

Tumors are surrounded by a variety of tumor microenvironmental cells. Profiling individual cells within the tumor tissues is crucial to characterize the tumor microenvironment and its therapeutic implications. Since single-cell technologies are still not cost-effective, scientists have developed many statistical deconvolution methods to delineate cellular characteristics from bulk transcriptome data. Here, we present an overview of 20 deconvolution techniques, including cutting-edge techniques recently established. We categorized deconvolution techniques by three primary criteria: characteristics of methodology, use of prior knowledge of cell types and outcome of the methods. We highlighted the advantage of the recent deconvolution tools that are based on probabilistic models. Moreover, we illustrated two scenarios of the common application of deconvolution methods to study tumor microenvironments. This comprehensive review will serve as a guideline for the researchers to select the appropriate method for their application of deconvolution.

• International Journal of Advanced Culture Technology
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• v.4 no.4
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• pp.45-50
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• 2016

This is a humanistic study to trace phenomena logically the comprehensive therapeutic mechanism of the human body which is coded by the smart emotion of the rated signal conveyed by the Rated Sijo. The Gestalt, which is structured in the form of therapeutic metastasis conveyed by sentences, is intended to embody the principle of human response. So, this researcher explored the metastatic structure toward Gestalt of original human being through the passage of foreground and background by ergonomic and chemical structure. In the meantime, this researcher focused on revealing the structure of the field of existence by the symbol system in which the therapeutic mechanism of the human body is embodied. As a result, the basic framework of Gestalt literary therapy, which contributes to the improvement of the Quality of Life metaphorized as a mechanism of the symbol system by the metastasis of literary therapy or the electrical operation of the human body. As a result, the human body as a conductor through literature has turned out to be an original Gestalt structure pursued by literature. In addition, it was analyzed that the human body would accept signals such as emotions and Rated Emotions planted in the sentence, and synapse them into the human physiological psycho analytical symbol system. Therefore, it has been confirmed possibility that human existent environment and trauma are separated from the whole universe can push fully implement therapeutic techniques toward totalization by a combination of literary devices, especially appropriate electric signal combination of the Rated Sijo.

• Radiation Oncology Journal
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• v.11 no.1
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• pp.183-191
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• 1993

The homogeneous dose planning is one of the most important roles in radiation therapy. But, it is not easy to obtain a homogeneous dose to paranasal sinus region including the ethmoidal sinus with conventional irradiation techniques. In this experimental study, the authors tried to get a homogeneous dose at PNS region, but the nasal cartirage does not exceed the tolerance dose, with anterior-posterior beam and two both lateral wedged beams. Used three fields were shielded with full thickness of blocks to preserve the eye-balls and with blocks of one half value layer to create a homogeneous dose at the whole treatment volume. The dose computations are based on the three dimensonal structure with modified scatter contributions of partial shielders and attenuated beams in 6 MV photon beams. The dose distributions of mid-plane is examined with Kodak verification films and teflon-embedded TLD rod (1 mm diameter and 6 mm length) to confirm the computed dose. In our study, the whole PNS regions have shown within $85{\%}$ of the resultant isodose curves with relatively homogeneous dose distribution. The results of dose computation and measurements are agree well within $5{\%}$ uncertainties.

• Molecules and Cells
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• v.25 no.4
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• pp.494-503
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• 2008

Many therapeutic glycoproteins have been successfully generated in plants. Plants have advantages regarding practical and economic concerns, and safety of protein production over other existing systems. However, plants are not ideal expression systems for the production of biopharmaceutical proteins, due to the fact that they are incapable of the authentic human N-glycosylation process. The majority of therapeutic proteins are glycoproteins which harbor N-glycans, which are often essential for their stability, folding, and biological activity. Thus, several glyco-engineering strategies have emerged for the tailor-making of N-glycosylation in plants, including glycoprotein subcellular targeting, the inhibition of plant specific glycosyltranferases, or the addition of human specific glycosyltransferases. This article focuses on plant N-glycosylation structure, glycosylation variation in plant cell, plant expression system of glycoproteins, and impact of glycosylation on immunological function. Furthermore, plant glyco-engineering techniques currently being developed to overcome the limitations of plant expression systems in the production of therapeutic glycoproteins will be discussed in this review.

• Journal of the Korean Home Economics Association
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• v.43 no.3 s.205
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• pp.161-183
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• 2005

This study aimed to develop a comprehensive group therapy program for divorced parents and their children for increased self-esteem, problem-solving technique, communication ability and emotional support. This comprehensive program was based on Solution-Focused and Satir's Experiential Family Therapy Models, as well as on therapeutic activities from various sources. Six mothers and 18 children of divorced families participated in this program which consisted of six, two-hour sessions. This program was found to be effective in enhancing the participants' self-esteem and communicative ability in addition to emotional support between mothers and their children, and among participants. Therapeutic activities were implemented in harmony with the Solution and Experiential based values and techniques, which seemed to heighten the fun and motivation for the participants to change their view points and behaviors in a positive way.

• Advances in pediatric surgery
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• v.7 no.1
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• pp.37-41
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• 2001

In hepatoblastoma, encouraging cure rates have been achieved with recent advances in chemotherapy and surgical techniques, The aim of this study is to evaluate the role of combined therapeutic modalities and surgical resection in hepatoblastoma. Fifteen cases of hepatoblastoma were treated from January 1993 to August 2000. Six patients had resectable tumors at initial diagnosis. All underwent surgical resection and in four patients postoperative adjuvant chemotherapy was needed. Nine out of 15 patients had unresectbale tumors at initial diagnosis, and preoperative chemotherapy was applied. There was one operative mortality and 14 patients showed good prognosis after surgery. Although various treatment modalities should be combined for the unresectable hepatoblastoma. surgical resection remains the major curative procedure.

• Nuclear Medicine and Molecular Imaging
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• v.42 no.2
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• pp.164-171
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• 2008

Medical internal radiation dosimetry (MIRD) is an important part of nuclear medicine research field using therapeutic radioisotope. There have been many researches using MIRD for the development of new therapeutic approaches including radiopharmaceutical, clinical protocol, and imaging techniques. Recently, radionuclide therapy has been re-focused as new solution of intractable diseases, through to the advances of previous achievements. In this article, the basic concepts of radiation and internal radiation dosimetry are summarized to help understanding MIRD and its application to clinical application.

• 대한핵의학회:학술대회논문집
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• 2002.05b
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• pp.77-95
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• 2002

During the last several decades, prognosis of differentiated thvroid cancers improved markedly, mainly due to refinement of surgical techniques and routine use of radioactive iodine. Total or neat-total thyroidectomy is to be performed as the first line of treatment. Routine remnant ablation just after surgery decreases recurrence and increases survival. After then patients are maintained on suppressive dose of thyroid hormone to keep endogenous TSH below normal. Regular follow-up of the patients with serum thyroglobulin measurement and iodine whole body scan after thyroid hormone withdrawal or under recombinant human thyrotropin stimulation select high risk patients with recurrence or metastatic disease and treatment with therapeutic dose of radioactive iodine prolongs survival and sometimes leads cure. Currently recommended diagnostic and therapeutic strategies, present controversies and future directions are discussed.