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Associations of Low Environmental Exposure to Multiple Metals with Renal Tubular Impairment in Korean Adults

  • Lim, Hyungryul;Lim, Ji-ae;Choi, Jong Hyuk;Kwon, Ho-jang;Ha, Mina;Kim, Heon;Park, Jung-duck
    • Toxicological Research
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    • v.32 no.1
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    • pp.57-64
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    • 2016
  • Recently several studies reported that the renal toxicity of lead (Pb) and cadmium (Cd) may exist in even a low level exposure. In terms of the deterioration of tubular function, it affects the loss of divalent metals and leads to other complications, so renal tubular effect of heavy metals should be well managed. Considering the exposure to heavy metals in reality, it is hard to find the case that human is exposed to only one heavy metal. We designed a cross-sectional study using Korean Research Project on the Integrated Exposure Assessment (KRIEFS) data to investigate the renal effects of multiple metal exposure in general population. We used blood Pb and urinary Cd as exposure measures, and urinary N-acetyl-${\beta}$-D-glucosaminidase (NAG) and ${\beta}_2$-microglobulin (${\beta}_2$-MG) as renal tubular impairment outcome. We conducted linear regression to identify the association between each heavy metal and urinary NAG and ${\beta}_2$-MG. And then, we conducted linear regression including the interaction term. Of 1953 adults in KRIEFS (2010~2011), the geometric mean of blood Pb and urinary Cd concentration was $2.21{\mu}g/dL$ (geometric $SD=1.49{\mu}g/dL$) and $1.08{\mu}g/g\;cr$ (geometric $SD=1.98{\mu}g/g\;cr$), respectively. In urinary Cd, the strength of the association was also high after adjusting (urinary NAG: ${\beta}=0.44$, p < 0.001; urinary ${\beta}_2$-MG: ${\beta}=0.13$, p = 0.002). Finally, we identified the positive interactions for the two renal biomarkers. The interaction effect of the two heavy metals of ${\beta}_2$-MG was greater than that of NAG. It is very important in public health perspective if the low level exposure to multiple heavy metals has an interaction effect on kidney. More epidemiological studies for the interaction and toxicological studies on the mechanism are needed.

A Survey of Chinese Men's Purchase Attitude and Size Fitness of Ready-Made Suits - Centered on the Area of Ningbo in Zhejiang Province - (중국 남성(中國 男性)의 기성복 정장(旣成服 正裝)에 대한 구매태도(購買態度) 및 사이즈 적합성(適合性)에 관(關)한 실태 조사(實態 調査) - 절강성 영파 지역(浙江省 寧波 地域)을 중심(中心)으로 -)

  • Shim, Boo-Ja;Suh, Chu-Yeon;Kwon, Young-Ja;Kwon, Soon-Jeong
    • Journal of Fashion Business
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    • v.10 no.2
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    • pp.83-98
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    • 2006
  • With the subjects of male consumers in their 20s to 40s living in the Ningbo area in Zhejiang Province, this study aims to investigate into the reality of their purchase attitude and size fitness of ready-made suits. The results are as follows; Looking into their demographic characteristics, 70.6% of the subjects were twenties, 60.6% were single, and educational career stood in the order of college, middle school, and high school graduation. They were largely absorbed in free trade, followed by teaching, commerce and service industry. 59.6% of them were Zhejiang Province belongs. One to two thousand yuan was the greatest portion of their monthly income. As for their purchase attitude of ready-made suits, they thought higher of material, quality, activity, and solidity than of design. They preferred to buy clothes at a department store. There was significant difference between purchase frequency and purchase price according to monthly income and jobs. Concerning brand recognition, the Chinese subjects favored "Youngor." Though Korea's brands were very lowly recognized, Korean products received really high recognition. Compared with China's brands, they found foreign brands excellent in design, followed by material/matter, wear, and sewing. As to their physical satisfaction and the size fitness of clothes, most subjects felt happy with their sizes. Trousers and jackets were among the unfitting suit items, while the girth of waist was the least satisfactory size. Therefore, in order to raise the market occupation rate of Korean suit goods in China, more aggressive marketing strategies are required to utilize the current Korean-style entertainment and maximize concerning brand images. In particular, outstanding products in consideration of prices should be made through the proper patternmaking to reflect the body types of the Chinese.

Improvement in Legislative Assessment of the Environmental Conservation Value Assessment Map Considering the Restriction on Acts of Special-Purpose Areas (용도 지역 행위 제한을 고려한 국토환경성평가지도 법제적 평가 개선)

  • Yang, Hyun-Jae;Kim, Geun-Han;Yoon, Jeong-Ho;Jun, Chul-Min;Lee, Eun-Jung;Hwang, So-Young
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.21 no.1
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    • pp.13-30
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    • 2018
  • In terms of environmental friendly land use and objective environmental assessment, legislative assessment items of Environmental Conservation Value Assessment Map (ECVAM) consists of designated areas related to conservation and protection, and areas that are planned to be designated in the future. However, the gap with the reality due to omission of several protection areas and land use regulations, and assessment grades according to 3 division land use map of forest, agricultural land, and urbanized area, results in low application and utilization of ECVAM. Therefore in this study, the legislative assessment of the ECVAM was performed with new assessment items and its new ratings, to suggest an improvement in legislative assessment items of the ECVAM. As a result, legally protected areas of inhabited islands under absolute conservation, special wildlife protection districts, protected marine areas, environmental preservation sea areas, scenic spots, forest protection zone, traditional temple preservation zone, and 45 zone or district related to regulation of land use were additionally designated as new legislative assessment items. New grade ratings were given to each additional assessment items in consideration of the restrictions on acts. As a result of the legislative assessment based on the new assessment items and new grades, the 1st grade area increased by 3.47%, and the 2nd grade area increased by 19.35%. The 3rd grade area decreased by 8.54%, the 4th grade area increased by 2.95%, and 5th grade increased by 2.91%. In addition, the out-of-grade area decreased by 20.14%, considered to be a realistic assessment based on land use. With the improved legislative assessment, it is possible to provide a more accurate environmental assessment map. Increase usage of ECVAM is expected in providing regulations of land use and base data for integrated land management of land environmental planning.

A Basic Study on The Management Plan of Traditional Gardens in Folk Houses as a Park (민가정원의 효율적 유지관리를 위한 공원화 방안에 대한 기초연구)

  • Yeom, Sung-Jin
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.33 no.3
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    • pp.50-57
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    • 2015
  • A traditional garden in Korea has diverse cultural, historical values, such as the then phases of the times, life phase, culture and art, etc. because it was developed on the basis of the harmony between nature and artificial structures. However, in reality, it's urgent to do efficient, continuous maintenance of traditional gardens which are being damaged and lost due to the problems like an owner's aging, inheritance, and lack of management, etc., especially in case of private property which was designated as a cultural property among such traditional gardens under the Cultural Properties Protection Law. Accordingly, this study conducted this research in a bid to use these research results as basic evidentiary materials for suggesting directivity in introduction of park planning of traditional gardens in folk houses in the near future by implementing the case investigation of transformation into public parks from traditional private gardens in Japan, which is putting the newly introduced park planning to efficient use, together with its systematic management, and the survey on domestic traditional gardens in folk houses status, as well as the hearing-based survey on a traditional gardens in folk houses owner's level of willingness to accept the introduction of parking planning. As a result, this study could confirm that in case of traditional gardens in Japan, they are mobilizing the revenue from admission fees for traditional gardens maintenance by incorporating the main entity of possession, and Japan is promoting transformation of traditional gardens into parks on the basis of use and preservation through the connection with local governments and research institutes. In addition, as a result of surveying domestic traditional gardens in folk houses, it was found that most of the garden owners had hardships in its management, and they were positive about systematic maintenance of gardens through park planning.

Operation Model Design of Logistics Industrial estate -Focused on Transportation Network- (물류산업단지의 운영모델 설계 - 운송 네트워크를 중심으로-)

  • Shin, Jae Young;Kim, Woong-Sub
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • 2013.06a
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    • pp.214-215
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    • 2013
  • Current competition among companies than regional, the time constraints, it is globalization, Tilt the efforts of many to be operated by building the efficient distribution system to reduce logistics costs and improve customer service it is reality's there. Therefore, the need for industrial complexes environmentally friendly can be cost competitive companies perform cavitation region's increased. To build the distribution center these logistics system through a joint of freight and appropriate policy is required. In particular, efficient operation through the system construction of industrial complexes in the logistics system is very important in terms of friendly low-cost urban logistics, the environment. Since the traffic volume which is Jipufa and utilization of network is transported by a more appropriate technicians and means suitable operating model can efficiency is improved. However, despite these advantages, research network design has not been actively conducted due to the complexity of the problem. Therefore, in this study, by analyzing the logistics system, and presents the operating model through a simulation and basic settings for the model of the logistics complex based on the analysis result, the construction of infrastructure of logistics industry complex it is intended to present the article.

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Geographical Name Denoising by Machine Learning of Event Detection Based on Twitter (트위터 기반 이벤트 탐지에서의 기계학습을 통한 지명 노이즈제거)

  • Woo, Seungmin;Hwang, Byung-Yeon
    • KIPS Transactions on Software and Data Engineering
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    • v.4 no.10
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    • pp.447-454
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    • 2015
  • This paper proposes geographical name denoising by machine learning of event detection based on twitter. Recently, the increasing number of smart phone users are leading the growing user of SNS. Especially, the functions of short message (less than 140 words) and follow service make twitter has the power of conveying and diffusing the information more quickly. These characteristics and mobile optimised feature make twitter has fast information conveying speed, which can play a role of conveying disasters or events. Related research used the individuals of twitter user as the sensor of event detection to detect events that occur in reality. This research employed geographical name as the keyword by using the characteristic that an event occurs in a specific place. However, it ignored the denoising of relationship between geographical name and homograph, it became an important factor to lower the accuracy of event detection. In this paper, we used removing and forecasting, these two method to applied denoising technique. First after processing the filtering step by using noise related database building, we have determined the existence of geographical name by using the Naive Bayesian classification. Finally by using the experimental data, we earned the probability value of machine learning. On the basis of forecast technique which is proposed in this paper, the reliability of the need for denoising technique has turned out to be 89.6%.

Love as Communication: Focusing on Dewey's Concept of Aesthetic Experience (소통으로서의 사랑 - 듀이의 미적 경험을 중심으로 -)

  • Ju, Seon-hee
    • Journal of Korean Philosophical Society
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    • v.130
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    • pp.337-361
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    • 2014
  • The main purpose of this paper is to reconstruct the modern thought of love in terms of Dewey's esthetic experience. In the contemporary Korean society, discussions of love are represented in the two tendencies, scientification of love and idealization of love. In actuality, they support the insistence of impossibility of love by the modern sociologists. The former deals with love as chemical reactions in brain, which is based on physiology and biology. The latter regards hypothetical love through the media as the idea of love and displaces concrete love in reality with it. To see love as the subject catching, understanding, and desiring the object depends upon a narrow concept of experience. It comes from the idea that experience is not doing and suffering in a concrete situation but knowing and understanding the object. In this case, the uniqueness and the qualitativeness with each experience of love are ignored. When these traits of a romantic relationship are disregarded, love cannot help but subordinate to the logic of capitalism. This paper, therefore, attempts to find a new way to understand experience of love, focusing on Dewey's concept of aesthetic experience. I suggest that we can expect the possibility of experience of love if love is experienced in a similar way with aesthetic experience based on emotional interaction, and that the very experience of love leads to growth of our personality. Furthermore, I think this communicative experience makes people to change their community as well as each person's private life.

A study on the Existential-Practical Perspective of Nietzsche's Philosophie (니체철학의 실존적-실천적 관점에 대한 연구)

  • Lee, Sang-bum
    • Journal of Korean Philosophical Society
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    • v.137
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    • pp.277-321
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    • 2016
  • Friedrich Nietzsche's philosophy embraces characteristics of existential philosophy and philosophical anthropology. In his book "Thus Spoke Zarathustra", Nietzsche defined human beings as an existence with innate possibility for change, beings that stand at the borderline between "the last man" and "the ${\ddot{u}}bermensch$", raising a question over the meaning of human being's existential healthiness. The anthropological symptoms that Nietzsche's philosophy deals with trigger existential problems, and healing these anthropological symptoms is a precedent to healing an existence. In Nietzsche's philosophy, the ${\ddot{u}}bermensch$ is presented as a prototype of practical man with a healthy existence, born from endeavors to heal the last man prototype of a decadence that was prevalent throughout Europe at the time. Nietzsche found the root cause of nihilism found in Europe in philosophy, religion, metaphysics, and Christianity, and attempted a genealogical investigation on this aspect. In so doing, a philosophical problem surfaced whereby only one truth was used to force diverse existential styles into a uniform style. Nietzsche intensively criticized philosophy and philosophers that only studied truths from metaphysical-Christian-moral perspectives, as they overlooked the foundation of true existence and presented human beings of a feeble mind and will as a result. Nietzsche emphasized the practical role of philosophy that can contribute to the human being's ascent and growth based on realistic conditions of human existence described as the earth, that philosophy that can serve as a basis for existential transformation of human beings and their lives. The task of philosophers is to lay the groundwork for the possibility of changes for all human beings and their realization. This existential practical foundation of philosophy can be called the ${\ddot{u}}bermensch$, as it is healthy man, the "greatest reality" as Nietzsche desired.

A New Model of Records Centers, Integration Archives : Reoranization of the Education office Records Centers (기록관의 새로운 모델, 통합기록관 교육청 기록관 체계의 재편성)

  • Lim, Hee-yeon
    • The Korean Journal of Archival Studies
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    • no.58
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    • pp.31-63
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    • 2018
  • The foremost priority for establishing record management of public institutions is strengthening the function and role of the records centers in the institutions and creating the foundation of the organization and personnel for demonstrating professionalism of archivists. However, concept of current records center is not clear and there is no substance of the organization. It also says that once a records manager is deployed, a records center is founded since appointment criteria for archivists is prone to be interpreted subjectively by the institutions. Therefore, it's time for more concrete improvements to resolve these issues. This research analyses some problems found in the system of records centers in the main office and district offices of education focusing on the environment of them. The problems are centers without substance in district offices of education because of the organization structure that all authority has been assembled in the main office, and the reality of records managers who have fallen into records discarders, etc. To solve these problems, this paper proposes changing the appointment criteria for archivists, operating an integrated records center reflecting the intensive working system, and legislating special act on record management of educational institutions.

A Study on the Different Perception of University life and the Level of Academic Competency by the Entrance Type (입학전형별 대학생활 인식차이 및 학업역량 수준분석)

  • Shim, Tae Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.7
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    • pp.372-379
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    • 2019
  • This study analyzed the thoughts of college life of students enrolled in each admission process to determine the level of academic competency. The satisfaction level of university life was analyzed among university students who studied at Dongguk University in 2012-2017 and the results were compared with the difference in importance and concentration of university life. Finally, the differences in scholastic ability around GPA were analyzed and compared. The results showed that students with pre-school grades were more satisfied with their college life than those with regular admissions. Although satisfaction with education is high during college life, it has been shown to be unsatisfactory regarding scholarships that are closely related to life. In terms of the difference between importance and concentration of college life, the greatest concern was with finding employment after graduation, but in reality the students could not focus on the current situation, but focused only on the current situation of grades and teamwork. The final admission GPA also showed that pre-school students were higher than regular students, and were able to adjust quickly to their school life and affect their satisfaction. Overall, education policies and programs are needed to understand the overall thoughts of university life and supplement them.