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Anesthetic Effects of the Xylazine-Tiletamine/Zolazepam(Zoletil$\circledR$) Combination in Dogs (Xylazine과 Tiletamine/Zolazepam(Zoletil$\circledR$)의 투여 농도 변화가 개의 마취에 미치는 영향)

  • 김준일;장환수;장광호
    • Journal of Veterinary Clinics
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    • v.21 no.2
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    • pp.168-171
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    • 2004
  • The effects of alterations of dose of xylaznie (X) and Zoltil$\circledR$ (TZ) on canine anesthesia were examined. Experimental groups were divided into three (Group 1: X 1.1 mg/kg and TZ 10 mg/kg, Group 2: X 1.65 mg/kg and TZ 7.5 mg/kg, Group 3: X 2.2 mg/kg and TZ 5 mg/kg), and each had 5 dogs. A femoral artery was catheterized for measurement of blood pressure, and baseline value was measured. The dogs were sedated with xylazine intramuscularly, then after 10 minutes TZ were injected intravenously. Mean arterial blood pressures (MAP), duration of analgesia, mean arousal time (MAT) and mean walking time (MWT) after TZ injection were measured, and the depth of analgesia and the quality of recovery were scored. The values of MAP were recorded from the time of pre-xylazine injection to arousal. Duration of analgesia and was assessed by tail clamping test, and which were done at 10 minutes intervals after TZ injection. The decreases of MAP from 40 minutes after TZ injection were significant (p<0.05). In group 2, MAP at 20 minutes, and from 40 minutes to arousal were significantly decreased (p<0.05). In group 3, MAP were significantly decreased from 40 minutes. MAT were 62.2$\pm$9.2 minutes in group 1, 60.2$\pm$7.5 minutes in group 2, and 71.0$\pm$6.9 minutes in group 3. MAT in group 3 was significantly increased compared with group 2 (p<0.05), and the differences of MWT among each groups were not significant (p>0.05). The scores of quality of recovery were significantly lowered in group 3 compared with group 1 or group 2, which means the side effects of recovery were less occurred. Thus, it was considered that the combination X 2.2 mg/kg IM and TZ 5 mg/kg IV is more effective to surgical procedures and to prevent long and rough recovery of Zoletil anesthesia.

A Efficacy of One-Stop Service in the Outpatient Clinic at the University Medical Center (3차 의료기관 외래진료에 있어 One stop service 도입의 효과)

  • Lee, Suk-Yeon;Chang, Sung-Goo
    • Korea Journal of Hospital Management
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    • v.6 no.2
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    • pp.70-85
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    • 2001
  • This study has been conducted, on the reservation of specific examinations during seven months starting from June 1999 and ending December as the Group I for these of one stop service and as the Group II for those of existing direct reservation made by patients or patrons, to understand the differences between the two groups. The survey was extended to the patients visiting specific departments of K hospital with sample sizes of 154 for the Group I and 155 for the Group II. The findings of the survey are as follows: First, as the general characteristics of the sample, male patients account for 67% of the total and female patients 33%, with the former twice as large as the latter. The average age of the patients is 51, indicating relatively high level. By the geographical area of residence, metropolitan area is 80.7% and the other area 19.3%, showing most of the patients are from metropolitan area. The general characteristics do not have statistical significance between the Group I and the Group II(p>0.05). Second, regarding the ratio by the number of examinations, the Group I shows 37.0% for one examination and 63.0% for two examinations, while the Group IT indicates 30.3% for one examination and 69.7% for two examinations. The populations by the number of examinations do not have statistical difference between the two Groups(p>0.05). Third, regarding the time required for the reservation of examinations by the number of examinations, the Group I shows 9.8 minutes for one examination and 19.8 minutes for two examinations, with the average of 16.1 minutes. The Group IT indicates 19 minutes for one examinations and 25.7 minutes for two examinations, with the average of 23.7 minutes. Though the time required for the reservation by the number of examinations do not have statistical significance, the time required for the Group I was shortened. Fourth, regarding the time required for the reservation of examinations by the age range of patients, the Group I shows 21.7 minutes for 70-79 years of age, 17.5 minutes for 60-00 years of age, and 15.2 minutes for 30-39 years of age. The Group II indicates 27.2 minutes for 70-79 years of age, 26.3 minutes for 60-69 years of age, 24.4 minutes for 50-59 years of age, and 22.4 minutes for 30-39 years of age. The time required for the reservation gets longer as the age range moves up, and has statistical significance (p<0.05). Fifth, regarding the ratio by the range of time of required for reservation, the Group I shows 41.6% for 11-20 minutes, and 38.3% for 1-10 minutes, while the Group II indicates 43.9% for 11-20 minutes, 29% for 21-30 minutes, and 14.2% for 31-40 minutes. Statistical significance is revealed (p=0.001). Sixth, concerning the length of movement course by the number of examinations, the Group I shows 37 meters regardless of the number of examinations. The Group II indicates an average of 188 meters for one examination and 189 meters for two examinations, with the difference 151 meters between the Groups, and representing statistical significance (p=0.001). Based on the above findings. one-stop service contributes to the reduction of both the time and the movement course and therefore is considered to be beneficial to the patients, and the improve the efficiency of the hospitals in terms of the space and the time.

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Effects of PNF and Respiratory Muscle Endurance Training on Lung Function and Physical Activity in Chronic Stroke Patients (고유수용성 신경근 촉진법과 호흡근 지구력 훈련이 만성 뇌졸중 환자의 폐 기능과 신체활동량에 미치는 영향)

  • Kim, Kyoung-Hun;Kim, Dong-Hoon
    • PNF and Movement
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    • v.18 no.2
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    • pp.205-214
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    • 2020
  • Purpose: The purpose of the study was to assess the effects of proprioceptive neuromuscular facilitation (PNF) training and respiratory muscle endurance training on pulmonary function and activity in chronic stroke patients. Methods: The participants were 25 chronic stroke patients. They were assigned to two groups: a PNF and respiratory muscle training group (experimental group; n = 12) and a conservative training group (control group; n = 13). The experimental group completed 50 minutes (30 minutes of conventional physical therapy, 10 minutes of PNF training, and 10 minutes of respiratory muscle endurance training). The control group also completed 50 minutes (30 minutes of conventional physical therapy and 20 minutes on a full-body workout machine). Pulmonary function and activity were measured before and after the intervention, using Cosmed to analyze pulmonary function and 6MWT as clinical evaluation indicators. Results: Both groups showed significant within-group differences on all tests before and after the intervention; the experimental group showed greater improvement on all tests. Conclusion: The findings confirm that PNF training and respiratory muscle endurance training have a positive effect on pulmonary function and activity index in chronic stroke patients.

Increasing Accuracy of Stock Price Pattern Prediction through Data Augmentation for Deep Learning (데이터 증강을 통한 딥러닝 기반 주가 패턴 예측 정확도 향상 방안)

  • Kim, Youngjun;Kim, Yeojeong;Lee, Insun;Lee, Hong Joo
    • The Journal of Bigdata
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    • v.4 no.2
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    • pp.1-12
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    • 2019
  • As Artificial Intelligence (AI) technology develops, it is applied to various fields such as image, voice, and text. AI has shown fine results in certain areas. Researchers have tried to predict the stock market by utilizing artificial intelligence as well. Predicting the stock market is known as one of the difficult problems since the stock market is affected by various factors such as economy and politics. In the field of AI, there are attempts to predict the ups and downs of stock price by studying stock price patterns using various machine learning techniques. This study suggest a way of predicting stock price patterns based on the Convolutional Neural Network(CNN) among machine learning techniques. CNN uses neural networks to classify images by extracting features from images through convolutional layers. Therefore, this study tries to classify candlestick images made by stock data in order to predict patterns. This study has two objectives. The first one referred as Case 1 is to predict the patterns with the images made by the same-day stock price data. The second one referred as Case 2 is to predict the next day stock price patterns with the images produced by the daily stock price data. In Case 1, data augmentation methods - random modification and Gaussian noise - are applied to generate more training data, and the generated images are put into the model to fit. Given that deep learning requires a large amount of data, this study suggests a method of data augmentation for candlestick images. Also, this study compares the accuracies of the images with Gaussian noise and different classification problems. All data in this study is collected through OpenAPI provided by DaiShin Securities. Case 1 has five different labels depending on patterns. The patterns are up with up closing, up with down closing, down with up closing, down with down closing, and staying. The images in Case 1 are created by removing the last candle(-1candle), the last two candles(-2candles), and the last three candles(-3candles) from 60 minutes, 30 minutes, 10 minutes, and 5 minutes candle charts. 60 minutes candle chart means one candle in the image has 60 minutes of information containing an open price, high price, low price, close price. Case 2 has two labels that are up and down. This study for Case 2 has generated for 60 minutes, 30 minutes, 10 minutes, and 5minutes candle charts without removing any candle. Considering the stock data, moving the candles in the images is suggested, instead of existing data augmentation techniques. How much the candles are moved is defined as the modified value. The average difference of closing prices between candles was 0.0029. Therefore, in this study, 0.003, 0.002, 0.001, 0.00025 are used for the modified value. The number of images was doubled after data augmentation. When it comes to Gaussian Noise, the mean value was 0, and the value of variance was 0.01. For both Case 1 and Case 2, the model is based on VGG-Net16 that has 16 layers. As a result, 10 minutes -1candle showed the best accuracy among 60 minutes, 30 minutes, 10 minutes, 5minutes candle charts. Thus, 10 minutes images were utilized for the rest of the experiment in Case 1. The three candles removed from the images were selected for data augmentation and application of Gaussian noise. 10 minutes -3candle resulted in 79.72% accuracy. The accuracy of the images with 0.00025 modified value and 100% changed candles was 79.92%. Applying Gaussian noise helped the accuracy to be 80.98%. According to the outcomes of Case 2, 60minutes candle charts could predict patterns of tomorrow by 82.60%. To sum up, this study is expected to contribute to further studies on the prediction of stock price patterns using images. This research provides a possible method for data augmentation of stock data.

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Effect of Pre-treatment Methods on the Quality Improvement of Persimmon Leaf Tea (전처리 조건이 감잎차의 품질 향상에 미치는 영향)

  • 김미자;오상룡
    • Food Science and Preservation
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    • v.6 no.4
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    • pp.435-441
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    • 1999
  • This study was carried out to sensory evaluation of persimmon leaf by roasting and steaming. The good sensory evaluation of persimmon leaf tea of cutting after different steamed times was shown in 3 minutes and 5 minutes steamed tea. Taste sensory score was increased in proportion to increasing of soluble solid and extraction yield and the increasing of color sensory score had relation to increasing of color value. The best sensory score was in roasted persimmon leaf tea of 5 minutes roasting in persimmon leaf tea of cutting after steaming of 3 minutes and 5 minutes. The best sensory score was shown in 3 minutes steamed in 5 minutes roasted which was culled after different steaming times. The total sensory non of roasted tea was influenced from preprocessing and total sensory score of roasted tea was higher than Just steamed tea. According to above result, the sensory score of roasted tea was more higher than steamed tea and the highest score was in 5 minutes roasted tea which was cutted after 3 minutes steamed.

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A Study on the Histopathological Changes of Experimental Bite-marks with the Progress of Time (실험교흔조직의 수상 후 경과시간에 따른 병리조직학적 변화에 관한 연구)

  • 윤창륙;김종열
    • Journal of Oral Medicine and Pain
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    • v.10 no.1
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    • pp.41-52
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    • 1985
  • In order to observe the histopathological changes with the progress of time after formation of bite-mark, experimental bite-marks were made in female rats and histopathological examinations were performed in the given sites immediately, 5 minutes, 10 minutes, 30 minutes, I hr., 4 hrs., 8 hrs., 12 hrs., 24 hrs., and 48 hrs, after injury. Results and Summary 1. Subcutaneous loose connective tissues and fatty layers were compressed immediately after formation of bite-marks, injured epithelia showed hydropic degeneration 5 minutes later. 2. Inflammatory cells emigrated into tissues with hemorrhages in the tissues after 10 minutes, and more increased centered around the blood vessels.- These distributed most densely in the tissues, after 12 hrs., thereafter, were decreased and distributed in various groups of crowdy appearances, after 48 hrs. 3. After 10 minutes, neutrophils emigrated into tissues and disappeared gradually with an appearance of monocytes. These disappeared completely, after 24 hrs. Lymphocytes and plasma cells were see n at 48 hrs. later. 4. Adherence of mast cells to injured sites occurred immediately, and which adhered to blood vessel walls of injured sites, after 10 minutes. 8 hrs. later, degranulation in emigrated inflammatory cells showed, and these degranulation disappeared gradually with a progress of time.

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The Effects of Transcutaneous Electrical Nerve Stimulation and Microampere Electrical Nerve Stimulation on Sympathetic Tone in Healthy Subjects (경피신경전기자극과 미세전류자극이 정상인의 교감신경 긴장도에 미치는 영향)

  • Park Rae-Joon
    • The Journal of Korean Physical Therapy
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    • v.9 no.1
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    • pp.51-57
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    • 1997
  • The purpose of this study was to determine the effect of two different forms of transcutaneous electrical nerve stimulation(TENS) and one of microcurrent high voltage pulsed galvanic current(HVPC) on sympathetic tone in healthy subjects. Fourty subjects received TENS(20) and PVPC(30) during short time(20min). Left finger tip skin temperatures were measured at four interval for each treatment : 1) before treatment, 2) after 10 minutes treatment, 3)after 20 minutes treatment, and 4) after 10 minutes rest. The results were as follows. 1) TENS treatment group increased skin temperature after treatment 20 minutes, but HVPC treatment increased akin temperature after 10 minutes and recovered normal skin temperature after 10 minutes treatment. It means that short time(20min) electrical stimulation decreased sympathetic activities. 2) Sympathetic activities of TENS stimulation were influenced by age, but HVPC were not. 3) During 10 minutes, both treatment increased sympathetic activities, but HVPC treatment reversed sympathetic activity more rapidly than TENS. 4) The changes of skin temperature means by sex, males in TENS treatment group were higher than females, but HVPC were reverted.

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A Comparison of Antioxidant Activities in Black Sesame Seeds according to Preparation and Cooking Conditions (흑임자의 조리 조건에 따른 항산화 효과의 비교)

  • Park, Jung-Lee;Chae, Kyung-Yeon;Hong, Jin-Sook
    • Journal of the East Asian Society of Dietary Life
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    • v.17 no.4
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    • pp.520-531
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    • 2007
  • In this study, we found that the moisture content of black sesame seeds increased in proportion to steaming time, and it decreased in reverse proportion to the roasting temperature and time. The crude fat and crude ash contents were shown to be in the order of steamed black sesame>raw black sesame and roasted black sesame>raw black sesame, Crude protein decreased in reverse proportion to the steaming time, and more crude protein was found in the raw black sesame samples than in the roasted black sesame samples. The contents of sesamin, sesamolin, and total lignans were shown to be in the order of roasted black sesame>raw black sesame>steamed black sesame. In the steamed black sesame samples, sesamin showed its highest level with 20 minutes of treatment, and sesamolin showed its highest level with 15 minutes of treatment. In the roasted black sesame samples, sesamin, sesamolin, and total lignans showed their highest levels with 15 minutes of treatment at $100^{\circ}C$. The phenolic compound content increased in proportion to steaming time in the steamed samples, and reached a peak after 15 minutes of treatment at $100^{\circ}C$, and then decreased after 20 minutes. SOD-like activity reached a peak after 15 minutes of treatment, and in the roasted sample it reached a peak after 15 minutes of treatment, and then decreased after 20 minutes. SOD-like activity was comparatively lower than tocopherol and higher than sesamol. The intensity of electron donating ability, following 30 minute treatments, was shown to be highest in the steamed black sesame samples after 25 minutes of treatment, and next highest in the roasted black sesame samples after 15 minutes at $100^{\circ}C$. The electron donating ability was comparatively lower than tocopherol and sesamol. With regard to lecithin's antioxidant effects, the steamed samples showed a higher oxidation restriction rate in proportion to time, and the roasted samples showed the highest rate after 15 minutes of treatment, and then decreased after 20 minutes of treatment. for hydroxyl radical scavenging, similar scavenging activity to tocopherol, and comparatively higher scavenging activity than sesamol, was shown in all samples: all samples showed scavenging abilities of 90% or higher. In summary, this study applied three different treatment methods to black sesame to determine the optimum treatment conditions, and also examined the antioxidant effects and functional characteristics. The results showed that roasting can be used for other purposes than producing oil, and also suggested that methods other than roasting can be used in a variety of ways in cooking. Also, the different treatment methods can be applied in cooking in a variety of ways, to enhance functionality and preference.

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The effects on fatigue and accuracy of cardiopulmonary resuscitation of the verbal-order method based on different time intervals (3, 4 minutes) (시간 (3분, 4분)에 따른 구령방법이 심폐소생술의 피로도와 정확도에 미치는 영향)

  • Lee, Mi Kyoung;Yang, Jeong Ok;Jung, Joo Ha;Lee, Kyeong Jun;Cho, Youngseuk
    • Journal of the Korean Data and Information Science Society
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    • v.27 no.2
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    • pp.409-417
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    • 2016
  • The purpose of this study was to demonstrate the effect on the degree of fatigue and accuracy of cardiopulmonary resuscitation according to the different time delays (3 minutes, 4 minutes). Carrying out repeated measures of variance (repeated ANOVA), we have shown that time effect (F = 7.835, p <.01) and group effect (F = 8.695, p<.01) and the interaction effect between time and group (F = 12.582, p<.001) were all statistically significant. It means, in the test of the main effect of group and time (3 minutes, 4 minutes) using the Bonferroni method, it turned out that the amount of lactic acid of the experimental group was larger than that of the control group (p<.01), and there was no difference until 3 minutes, but the difference of the amount of lactic acid was shown between before the experiment and after 4 minutes, and between 3 minutes and 4 minutes (p <.05), respectively. Then, in the result of the corresponding sample t-test, for comparing the according to the measurement time, the accuracy after 3 minutes became higher than the case of 4 minutes (t = 4.584, p <.001). Therefore, before 119 arrives performing cardiopulmonary resuscitation for emergency, rescuers need to perform cardiopulmonary resuscitation alternating with others before 3 minutes.

Preparation of In Vivo Rat Lung Model for Ischemia-Reperfusion Injury (허혈 재관류 손상 실험의 쥐 생체 모델 작성)

  • Lee, Won-Jin;Park, Hui-Cheol;Hong, Gi-U
    • Journal of Chest Surgery
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    • v.28 no.11
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    • pp.963-966
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    • 1995
  • Ischemia reperfusion injury occurs in various diseases. The role of oxygen free radicals in IR injury of the lung has been spotlighted and many studies have been performed. In this study, we tried to prepare a stable rat lung model for IR injury, focusing on surrounding conditions as hilar stripped left lung, clamped left pulmonary artery and bronchus,and declamped after determined period was passed, and right main pulmonary aretery was clamped. Arterial blood gas analyes were performed at 1, 10, 20, 30, minutes after reperfusion. Before clamping, PaO2 was 95 to 120 mmHg in all animals. There were six groups; Group I : temperature 15o C, and 120 minutes clamping, Group II: 20 oC, and 120 minutes clamping, Group III : 25 oC, and 120 minutes clamping, Group IV : 15oC, 90 minutes clamping, Group V : 20 oC, 90 minutes clamping,Group VI: 20 oC, 75 minutes clamping. Each groups contained 10 Sprague Dayley rats. The humidity was maintained 100 % as circulation imerged isotonic Hartmann`s solution of the pleural cavity. In group IV, V, and VI, PaO2 decreased significantly in all animals immediately after reperfusion, but 43 % survived till 10 minutes after reperfusion, it was 74.0$\pm$5.7, 73.3$\pm$10.8,and 88.2$\pm$17.7 mmHg. Pulmonary edema was observed histologically in 2/10 animals in group IV, 6/10 in group V , 3/10 in group VI, 9/10 in group I, and the other lungs showed all edema. We established a stable model by setting ischemic time,and temperature, between 75 to 90 minutes,15 to 20o C, and isotemperature Hartmann`s solution immersion of the pleural cavity.

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