• 제목/요약/키워드: the early-aged adult

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소아기 수면 장애 (Sleep disorders in childhood)

  • 차병호
    • Clinical and Experimental Pediatrics
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    • 제50권8호
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    • pp.718-725
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    • 2007
  • Sleep disorders are very common among pediatric patients. Its prevalence is between 10% and 45% in preschool- and school-aged children. However parents commonly do not concern about their children's sleeping habits and for many pediatricians, there is not part of the routine office visit about a childs sleep. Sleep disorders were classified by International Classification of Sleep Disorder (ICSD) as dyssomnias, parasomnias, sleep disorders associated with mental, neurologic, or other medical disorders, and proposed sleep disorders. There are lots of differences in the causes, manifestations, and managements of sleep disorders between children and adult. The sleep disorders in childhood may manifest themselves as bedtime resistance, refusal to go to bed at a parentally described time, sleep-onset delay, inability to fall asleep within a reasonable time, prolonged nighttime awakening, and inability to return to sleep without assistance after waking during the night, and so have wide-ranging influences on children's behavior, mood, school performance, and family life. It's very important for pediatrician to concern about the sleep disturbances in childhood and so the problems of sleep in children should be early detected and managed.

Change in the height of Korean children and adolescents: analysis from the Korea National Health and Nutrition Survey II and V

  • Ryoo, Na Yung;Shin, Ha Young;Kim, Jae Hyun;Moon, Jin Soo;Lee, Chong Guk
    • Clinical and Experimental Pediatrics
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    • 제58권9호
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    • pp.336-340
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    • 2015
  • Purpose: The mean adult height of Koreans has increased since nationwide anthropological measurements began in 1967. The objective of this study was to evaluate differences in heights of Korean late adolescents and young adults within and between the Second and Fifth Korea National Health and Nutrition Examination Surveys (KNHANES II and V). Methods: Koreans aged ${\leq}22$ years with available measurements of height were enrolled from the KNHANES surveys (KNHANES II: n=3,372 [1,732 males and 1,640 females]; KNHANES V: n=6,190 [3,198 males and 2,992 females]). Differences in the height of KNHANES respondents within and between surveys were evaluated according to age and sex. Results: In KNHANES II, there was no significant difference in height between males aged 17-19 years and those aged 20-22 years ($174.3{\pm}0.5cm$ vs. $174.3{\pm}0.6cm$, P=0.995). Females aged 20-22 years were taller than those aged 17-19 years ($159.8{\pm}0.4cm$ vs. $161.0{\pm}0.4cm$, P=0.017). Females aged 17-19 years were significantly taller in KNHANES V than in KNHANES II ($161.2{\pm}0.3cm$ vs. $159.8{\pm}0.4cm$, P=0.004). Respondents aged 20-22 years were taller in KNHANES V than in KNHANES II, although not significantly so; the difference was $0.3{\pm}0.8cm$ in males (P=0.721) and $0.5{\pm}0.6cm$ in females (P=0.386). Conclusion: Koreans appear to continue growing even in their late adolescence and early twenties. Consequently, it may be necessary to expand the reference age ranges of the Korean growth chart. Additionally, a longitudinal growth survey is needed to determine growth patterns and secular trend in height among Koreans.

운동훈련이 흰쥐 노화심근에 미치는 영향 I. 장기간 지구력 운동 훈련 (Effects of the Exercise Training on Aging Heart in Rat I. Long Term Endurance Exercise)

  • 박원학;이상선;이용덕
    • 대한의생명과학회지
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    • 제2권1호
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    • pp.71-90
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    • 1996
  • 장기간 반복 주행운동이 횐 쥐의 심근에 미치는 효과를 규명하기 위하여 생후 3개월,10개 월 및 20개월 된 횐 쥐를 운동군과 대조군으로 대별하여 motor driven treadmill을 이용하여 Park등이 사용한 방법에 준해서 5개월간, 주 5일 20분간 운동을 시킨 후 심근의 조직 및 세포학적 변화를 관찰하고 심근 세포 내 미세구조 변화를 입체해석학적으로 비교 분석하였다. 연령 증가에 따라 장기간 반복운동이 휜쥐 심근미세구조에 미치는 영향은 8, 15개월의 운동군과 대조군 사이에 뚜렷한 차이를 인정할 수 없으며, 15개월의 운동군에서 대조군에 비하여 변성된 사립체, 리소조옴, 지방적, 공포, 노화색소 등이 증가하는 경향이 있었다. 25개월 운동군은 같은 연령 대조군에 비하여 근원섬유 수축대, 근원섬유 소실, 윤반분리,세포간질 증식, 핵의 변성,교원섬유 근섬유내 침입 등 매우 심한 변화를 보였다. 조직상에 나타나는 early lipofusin과 미세구조상에 나타나는 노화색소는 8, 15개월의 운동군과 대조군 사이에 유의한 차이는 없었으며, 25개월 운동군은 같은 연령 대조군에 비하여 유의한 차이로 증가하였다. Glucose-6-phosphatase 활성도 8, 15개월군에서 운동군과 대조군에서 모두 활성이 높았으며 25개월의 대조군과 운동군에서는 모두 활성이 거의 나타나지 않았다. 미세구조 변화를 입체해석학적으로 분석한 결과 8, 15개월의 대조군과 운동군에서 체적 밀도의 모든 항은 양군사이에 유의한 차이가 없었다. 25개월에서는 세포간질이 대조군에 비하여 운동군이 유의한 증가를 나타내었고, 근원섬유는 유의한 차이는 없지만 증가하는 경향을 보였으며, 사립체는 대조군에 비하여 유의 한 감소를 나타내었고 근형질세망의 체적밀도는 감소하는 경향을 보였다. 사립체와 근원섬유 비는 8개월 운동군에서 유의한 차이는 없지만 대조군에 비하여 높게 나타났으며, 15개월의 운동군과 대조군 사이에서는 차이를 인정할 수 없었다. 그러나 25개월 운동군은 대조군에 비하여 유의한 차이로 감소하였다. 연령증가에 따른 사립체 내막 표면밀도와 사립체수는 대조군과 운동군 사이에는 유의한 변화는 없었다. 본 연구의 성적을 검토한 결과 젊은층(3개월군)과 중령층(10개월군)의 횐 쥐에서는 반복된 지구력운동이 심장에 미치는 역효과를 인정할 수 없었으며 젊은 층의 횐 쥐에서는 오히려 심장기능 강화를 보이는 경향이 나타났으며, 노화층(20개월군)에서 운동군에서는 스트레스로 작용하여 심장기능의 저하를 초래하였다고 생각된다.

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사료내 조단백질 수준이 진도성견의 질소균형에 미치는 영향 (Effects of Crude Protein Levels on Nitrogen Balance in Adult Jindo Dog)

  • 강태일;맹원재;김명화;이상락
    • Journal of Animal Science and Technology
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    • 제51권2호
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    • pp.155-162
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    • 2009
  • 본 연구는 진도성견의 단백질 급여수준이 질소균형에 미치는 영향을 조사하여 단백질 급여 표준을 설정하기 위한 기초 자료를 얻기 위하여 실시하였다. 진도견 성견초기(생후 36~38주령)와 성견후기(생후 45~49주령)의 암컷 12두를 대상으로 단백질 수준을 17, 19 및 21%로 설정한 실험사료를 급여하여 체중, 사료섭취량 및 분뇨 배설량을 측정하였다. 성견초기의 일당 증체량은 조단백질 함량 17, 19 및 21%구에서 각각 -38.33, -16.25 및 -12.71g으로 나타났으며 17% 조단백질 사료급여구가 19 및 21% 급여구에 비하여 유의하게 낮았다(p<0.05). 축적된 질소량은 각각 -0.29, -0.04 및 -0.03g/kg$BW^{.75}$/d로 계산되었으며 조단백질 17% 급여구가 19 및 21% 급여구에 비하여 유의하게(p<0.05) 낮은 결과를 나타내었다. 질소섭취량(x)과 질소축적량(y)간에 y = 0.7484x-1.18 ($R^2$ = 0.9923)의 회귀식이 도출되었으며, 이 식으로부터 성견초기의 유지 조단백질 요구량은 9.85g/kg$BW^{.75}$/d로 추정되었다. 진도견 성견후기의 일당 증체량은 실험구 별로 각각 -34.05, -28.71 및 -28.28g으로 17% 단백질 사료급여구가 다른 구에 비하여 낮게 나타났으나 유의한 차이는 아니었다. 축적된 질소량은 각각 -0.33, -0.06 및 -0.09g/kg$BW^{.75}$/d로 계산되었으며 17% 조단백질 급여구가 19 및 21% 급여구에 비하여 유의하게(p<0.05) 낮은 결과를 나타내었다. 질소섭취량(x)과 질소축적량(y)간에 y = 0.8823x-1.0894 ($R^2$ = 0.9982)의 회귀식이 도출되었으며 이식을 이용하여 계산한 결과 성견후기의 유지 조단백질 요구량은 7.72g/kg$BW^{.75}$/d로 추정되었다. 본 연구는 우리나라에서 진도견을 대상으로 한 영양소 요구량을 설정하기 위한 최초의 연구로 생각되며 연구의 결과는 진도견의 단백질 요구량을 설정하는데 기초 자료가 될 것으로 생각된다. 그러나 진도견의 단백질 요구량을 최종적으로 설정하기 위해서는 전 생애에 걸쳐서 성별 및 사육환경에 따른 영양소 요구량에 대한 추가적인 연구가 필요하다고 사료된다.

일개 지역사회 여성 주민의 자궁경부암 조기검진 수검에 관한 행동변화단계별 교육 프로그램의 효과 (Effectiveness of stages-matched educational program for cervical cancer screening among adult women in a community)

  • Kim, Young-Bok
    • 보건교육건강증진학회지
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    • 제24권5호
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    • pp.23-37
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    • 2007
  • 연구 배경: 자궁경부암은 조기검진을 통해 사망률과 의료비 부담을 감소시킬 수 있는 질환으로, 아직까지 우리나라에서는 자궁경부암이 여성암 중 높은 발생률을 보이고 있으나, Pap test를 통해 자궁경부암을 조기에 발견하고, 치료할 수 있는 것으로 알려져 있다. 연구 목적: 이 연구는 자궁경부암 조기검진 수검행동에 영향을 미치는 인지-행동적 요인을 고려하여 행동변화단계별 교육 프로그램을 개발하였고, 이를 40세 이상의 여성 주민에게 적용해봄으로써 행동변화단계별 맞춤형 교육 프로그램의 효과를 평가하고자 하였다. 연구 방법: 이 연구는 서울시 서초구에 거주하는 40세$\sim$59세 사이의 여성 주민을 대상으로 2003년 9월 1일부터 11월 14일까지 자료를 수집하였으며, 서초구의 5개 지역(동)에서 교육 중재군(162명)과 대조군(121명)을 선정하였다. 또한 행동변화단계별 교육 프로그램은 범이론적모형(TTM)을 활용하여 개발되었고, 교육 중재군의 교육내용 전달방법으로 인터넷 서비스와 우편 서비스가 활용되었다. 연구 결과: 조사대상자중 88.9%가 일생 중 1번 이상, 65.4%가 최근 2년 동안 1번 이상 자궁경부암 조기검진을 수검한 것으로 나타났다. 행동변화단계별 교육 프로그램의 효과를 살펴보면, 교육 후 인지 행동적 요인 중 태도와 변화의 과정이 통계적으로 유의하게 높아졌고, 행동변화단계 중 유지단계가 가장 많이 증가하였다. 교육내용 전달 방법은 인쇄된 교육자료를 활용한 우편 서비스가 인터넷 서비스보다 효과적인 것으로 나타났고, 행동변화단계별 전환 양상에서도 우편 서비스 중재군이 인터넷 서비스 중재 군보다 긍정적인 변화를 나타내었다. 한편 행동변화단계별 교육 프로그램에 관한 만족도 평가에서는 전달방법에 따른 유의한 차이가 없는 것으로 나타났다. 결론: 이 연구는 지역사회 여성 주민의 자궁경부암 조기검진에 관한 수검 행동을 증진시키기 위해 행동변화단계에 따른 맞춤형 교육 프로그램을 개발하여 적용하였고, 그 결과, 행동변화단계별 교육 프로그램이 자궁경부암 조기검진의 수검 행동을 증진시키는데 효과적인 것으로 나타났다.

지역사회 거주 여성노인의 근감소성 비만 유병률과 관련요인 (Prevalence and Factors Related to Sarcopenic Obesity among Community-dwelling Elderly Women)

  • 이민혜;박연환
    • Journal of Korean Biological Nursing Science
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    • 제19권1호
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    • pp.30-37
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    • 2017
  • Purpose: The aims of this study were to identify prevalence and identify factors related to sarcopenic obesity among community-dwelling elderly women. Methods: This is a secondary analysis of the prospective cohort study. Our analysis included 338 elderly women (${\geq}65$ years old) in South Korea as a part of the Community-dwelling Older Adult Health Cohort (COHC) Study (2014-2015). Sarcopenic obesity was defined as the Asian Working Group of Sarcopenia recommendations and upper two quintiles for percentage body fat. Logistic regression analysis was used to determine the factors related to sarcopenic obesity including chronic diseases, medications, stress, fatigue, depression, exercise, level of proteins on body compositions, smoking, and alcohol use. Results: The prevalence of sarcopenic obesity was 6.2%. A lower protein on body compositions (OR 0.017, 95% CI 0.003-0.081, p< .001), a larger number of medications (OR 2.104, 95% CI 1.404-3.152, p< .001), and a higher level of fatigue (OR 1.255, 95% CI 1.023-1.541, p= .030) were related factors of sarcopenic obesity. Conclusion: The findings suggest that nutritional interventions focusing on protein intakes should be needed to prevent sarcopenic obesity among the elderly women. Polypharmacy issue for preventing adverse outcomes and level of fatigue as indicator for early identification are also considered to develop community prevention programs.

성인여성의 생애주기별 외모만족도, 자아존중감, 우울, 스트레스 및 건강관련 삶의 질 간의 관계 (Relationship of Satisfaction with Appearance, Self-Esteem, Depression, and Stress to Health Related Quality of Life in Women across the Lifespan)

  • 박영례;손연정
    • 기본간호학회지
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    • 제16권3호
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    • pp.353-361
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    • 2009
  • Purpose: The purpose of this study was to examine the relationship of adult the women's satisfaction with their appearance, self-esteem, depression and stress to health related quality of life (HRQOL) across the lifespan. Method: In this study a convenience sample of Korean women aged 20 years and over was used. There were 1152 women and data were collected from November 2007 to February 2008. Results: There was no difference in satisfaction with appearance in all age group. Elderly women reported lowest self esteem and HRQOL and highest depression and stress. There were statistical significances between satisfaction with appearance, self-esteem, depression, stress and HRQOL for all age groups. The most significant predictors of HRQOL in early adulthood women were stress and depression. The most significant predictors of HRQOL in middle adulthood women were stress, disease, depression, self-esteem, and monthly income. The most significant predictors of HRQOL in elderly women were stress, disease, depression, and satisfaction with appearance. Conclusion: The results indicate that HRQOL of Korean women is associated with psychological distress as with stress and depression. When developing programs to enhance health in elderly women, consideration should be given to body image as well as psychological distress and chronic conditions.

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Uncoupling Protein, UCP-4 May Be Involved in Neuronal Defects During Aging and Resistance to Pathogens in Caenorhabditis elegans

  • Cho, Injeong;Hwang, Gyu Jin;Cho, Jeong Hoon
    • Molecules and Cells
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    • 제39권9호
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    • pp.680-686
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    • 2016
  • Uncoupling proteins (UCPs) are mitochondrial inner membrane proteins that function to dissipate proton motive force and mitochondrial membrane potential. One UCP has been identified in Caenorhabditis elegans (C. elegans), namely UCP-4. In this study, we examined its expression and localization using a GFP marker in C. elegans. ucp-4 was expressed throughout the body from early embryo to aged adult and UCP-4 was localized in the mitochondria. It is known that increased mitochondrial membrane protential leads to a reactive oxygen species (ROS) increase, which is associated with age-related diseases, including neurodegenerative diseases in humans. A ucp-4 mutant showed increased mitochondrial membrane protential in association with increased neuronal defects during aging, and the neurons of ucp-4 overexpressing animals showed decreased neuronal defects during aging. These results suggest that UCP-4 may be involved in neuroprotection during aging via relieving mitochondrial membrane protential. We also investigated the relationship between UCP-4 and innate immunity because increased ROS can affect innate immunity. ucp-4 mutant displayed increased resistance to the pathogen Staphylococcus aureus compared to wild type. The enhanced immunity in the ucp-4 mutant could be related to increased mitochondrial membrane protential, presumably followed by increased ROS. In summary, UCP-4 might have an important role in neuronal aging and innate immune responses through mediating mitochondrial membrane protential.

Heart Failure With Preserved Ejection Fraction and Frailty: From Young to Superaged Coexisting HFpEF and Frailty

  • Amina Rakisheva;Anzhela Soloveva;Anastasia Shchendrygina;Ilya Giverts
    • International Journal of Heart Failure
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    • 제6권3호
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    • pp.93-106
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    • 2024
  • Being commonly diagnosed in elderly women and associated with comorbidities as well as ageing-related cardio-vascular changes, heart failure with preserved ejection fraction (HFpEF) has been recently considered as a distinct cardiogeriatric syndrome. Frailty is another frequent geriatric syndrome. HFpEF and frailty share common underlying mechanisms, often co-exist, and represent each other's risk factors. A threshold of 65 years old is usually used to screen patients for both frailty and HFpEF in research and clinical settings. However, both HFpEF and frailty are very heterogenous conditions that may develop at younger ages. In this review we aim to provide a broader overview on the coexistence of HFpEF and frailty throughout the lifetime. We hypothesize that HFpEF and frailty patients' profiles (young, elderly, superaged) represent a continuum of the common ageing process modified by cumulative exposure to risk factors resulting to a presentation of HFpEF and frailty at different ages. We believe, that suggested approach might stimulate assessment of frailty in HFpEF assessment and vice versa regardless of age and early implementation of targeted interventions. Future studies of pathophysiology, clinical features, and outcomes of frailty in HFpEF by age are needed.

The Association of Smoking Status and Clustering of Obesity and Depression on the Risk of Early-Onset Cardiovascular Disease in Young Adults: A Nationwide Cohort Study

  • Choon-Young Kim;Cheol Min Lee;Seungwoo Lee;Jung Eun Yoo;Heesun Lee;Hyo Eun Park;Kyungdo Han;Su-Yeon Choi
    • Korean Circulation Journal
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    • 제53권1호
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    • pp.17-30
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    • 2023
  • Background and Objectives: To evaluate the impact of smoking in young adults on the risk of cardiovascular disease (CVD) and the clustering effect of behavioral risk factors such as smoking, obesity, and depression. Methods: A Korean nationwide population-based cohort of a total of 3,280,826 participants aged 20-39 years old who underwent 2 consecutive health examinations were included. They were followed up until the date of CVD (myocardial infarction [MI] or stroke), or December 2018 (median, 6 years). Results: Current smoking, early age of smoking initiation, and smoking intensity were associated with an increased risk of CVD incidence. Even after quitting smoking, the risk of MI was still high in quitters compared with non-smokers. Cigarette smoking, obesity, and depression were independently associated with a 1.3-1.7 times increased risk of CVD, and clustering of 2 or more of these behavioral risk factors was associated with a 2-3 times increased risk of CVD in young adults. Conclusions: In young adults, cigarette smoking was associated with the risk of CVD, and the clustering of 2 or more behavioral risk factors showed an additive risk of CVD.