• Journal of Korean society of Dental Hygiene
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• v.20 no.6
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• pp.855-864
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• 2020

Objectives: The aim of this study was to investigate the effects of periodontal disease in menopausal women. Methods: We used data from the 7th (2016-2018) Korea National Health and Nutrition Examination Survey. The subjects of the study were 2,643 women aged 40 to 59 years who participated in the periodontal examination and answered a menses questionnaire. The data were analyzed using complex samples multivariate logistic regression to investigate the effects related to periodontal disease in menopausal women. Results: After adjusting for general characteristics, oral health behaviors, and health status, those aged 50-59 years had odds ratio (OR) for periodontal disease of 2.52 compared to those aged 40-49 years. Compared to those who brushed 3 or more times a day, those with less than 3 brushings a day had OR of 1.48. Those who smoked had a 3.00 higher risk of periodontal disease than those who were non-smokers. Further, those with glycosuria had a 2.26 higher risk of periodontal disease than those without glycosuria. Conclusions: In order to promote the oral health of menopausal women, it is suggested that comprehensive and systematic oral health education should be implemented considering various variables.

• Journal of Korean society of Dental Hygiene
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• v.16 no.1
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• pp.1-9
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• 2016

Objectives: The purpose of the study was to identify the oral care status and periodontal disease of middle aged daibetic patients in Korea. Methods: The primitive data were taken from 238 diabetic people in the 5th Korea National Health and Nutrition Examination Survey(KNHANES) in 2010 - 2012. The variables included general profiles(gender, age, occupied area, education, and smoking), oral care status(brushing time, brushing time, use of oral hygienic supplies, availability of oral hygienic supplies, oral examination, and recognition of oral health state), and diabetes management(morbidity period, treatment, education, and glycosylated hemoglobin levels). Results: Most of the subjects took gargling more than twice a day and it accounted for 73.5%. Oral hygienic supply users accounted for 24.8%, and most of them used floss brush. Oral examination was done in 19.3% of the respondents and 55.0% thought that their oral health status were very poor. The prevalence rate of the periodontal diseases was 46.6%. Female tended to have a higher rate of periodontal disease than the male. Oral hygienic supply users had lower rate of periodntal disease than those who did not use. Those who had poor subjective oral health status had higher prevalence rate of periodontal disease than those who did not. Conclusions: Periodontal disease is closely related to good oral care of middle aged diabetic patients. It is necessary to develop the program for the prevention of the periodontal disease for the diabetic patients.

• The Korean Journal of Physiology and Pharmacology
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• v.18 no.2
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• pp.95-101
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• 2014

Cardiovascular disease is the prime cause of morbidity and mortality and the population ages that may contribute to increase in the occurrence of cardiovascular disease. Arginase upregulation is associated with impaired endothelial function in aged vascular system and thus may contribute to cardiovascular disease. According to recent research, Korean Red Ginseng water extract (KRGE) may reduce cardiovascular disease risk by improving vascular system health. The purpose of this study was to examine mechanisms contributing to age-related vascular endothelial dysfunction and to determine whether KRGE improves these functions in aged mice. Young ($10{\pm}3$ weeks) and aged ($55{\pm}5$ weeks) male mice (C57BL/6J) were orally administered 0, 10, or 20 mg/mouse/day of KRGE for 4 weeks. Animals were sacrificed and the aortas were removed. Endothelial arginase activity, nitric oxide (NO) generation and reactive oxygen species (ROS) production, endothelial nitric oxide synthase (eNOS) coupling, vascular tension, and plasma peroxynitrite production were measured. KRGE attenuated arginase activity, restored nitric oxide (NO) generation, reduced ROS production, and enhanced eNOS coupling in aged mice. KRGE also improved vascular tension in aged vessels, as indicated by increased acetylcholine-induced vasorelaxation and improved phenylephrine-stimulated vasoconstriction. Furthermore, KRGE prevented plasma peroxynitrite formation in aged mice, indicating reduced lipid peroxidation. These results suggest KRGE exerts vasoprotective effects by inhibiting arginase activity and augmenting NO signaling and may be a useful treatment for age-dependent vascular diseases.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.05a
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• pp.48-49
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• 2015

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2015.05a
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• pp.63-63
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• 2015

• The Korean journal of internal medicine
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• v.33 no.6
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• pp.1182-1193
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• 2018

Background/Aims: Elderly patients (${\geq}80years$) with colorectal cancer (CRC) tend to avoid active treatment at the time of diagnosis despite of recent advances in treatment. The aim of this study was to determine treatment propensity of elderly patients aged ${\geq}80years$ with CRC in clinical practice and the impact of anticancer treatment on overall survival (OS). Methods: Medical charts of 152 elderly patients (aged ${\geq}80years$) diagnosed with CRC between 1998 and 2012 were retrospectively reviewed. Patients' clinical characteristics, treatment modalities received, and clinical outcome were analyzed. Results: Their median age was 82 years (range, 80 to 98). Of 152 patients, 148 were assessable for the extent of the disease. Eighty-two of 98 patients with localized disease and 28 of 50 patients with metastatic disease had received surgery or chemotherapy or both. Surgery was performed in 79 of 98 patients with localized disease and 15 of 50 patients with metastatic disease. Chemotherapy was administered in only 24 of 50 patients with metastatic disease. Patients who received anticancer treatment according to disease extent showed significantly longer OS compared to untreated patients (localized disease, 76.2 months vs. 15.4 months, p = 0.000; metastatic disease, 9.9 months vs. 2.6 months, p = 0.001). Along with anticancer treatment, favorable performance status (PS) was associated with longer OS in multivariate analysis of clinical outcome. Conclusions: Elderly patients aged ${\geq}80years$ with CRC tended to receive less treatment for metastatic disease. Nevertheless, anticancer treatment in patients with favorable PS was effective in prolonging OS regardless of disease extent.

• Journal of the Korean Society of Food Culture
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• v.16 no.2
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• pp.137-146
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• 2001

Purpose of this study was to investigate the health status and life style of middle-aged people in Daejon. The subjects expressed more fear for disease as getting older(p<0.01). Sixty six percent of the subjects have suffered in the past or suffer at present certain kinds of disease. The older they are, the more disease they have. The alimentary disease, neuralgia, and arthritis were the most popular disease. The eye strain and exhaustion of body were indicated more frequently in fifties than in thirties or forties(p<0.01). They considered excercise as the most important factor to maintain health status, and then moderation in diet, relaxation, rest, decrease of alcohol intake, no smoking. Forty three percent of them were non-drinker. The number of drinker was four times more in male than female and increased as getting younger(p<0.01). Only male revealed smoker and 29% of them smoked 10-20 cigarettes per day. The number of smoker decreased as getting older(p<0.01). Male played exercise more regularly than female and subjects have better exercise habit as getting older(p<0.01). This study suggests that practical programs for self-health control should be developed for playing exercise regularly for female and for considering nutrition, no smoking, and no drinking in the daily life for male.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2014.11a
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• pp.187-187
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• 2014

In this study, we investigated mechanical properties and surface characteristics of Ti-25Ta-xHf alloys. The samples were manufactured for composition of Ti-25Ta-xHf(x=0 to 15 wt. %) alloys. Each alloy was melted twenty times in an arc-melting vacuum furnace. The microstructural phases and phase transformation of Ti-25Ta-xHf alloys were identified with the aid of an XRF, XRD and DSC. And mechanical properties were investigated using Vickers hardness, nanoindentation, and tensile test.

• Proceedings of the Korean Institute of Surface Engineering Conference
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• 2012.05a
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• pp.331-331
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• 2012

In this study, we investigated morphology observation of nanostructured Ti-25Ta-xZr alloys. Ti-25Ta-(3wt%~15 wt%) Zr alloys were prepared by a vacuum arc-melting furnace. Formation of nanotubular structure was achieved by an electrochemical method in 1M $H_3PO_4$ electrolytes containing 0.8%wt.% NaF. Nanotube morphology depended on alloying elements.

• Journal of The Korean Society of Integrative Medicine
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• v.4 no.2
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• pp.97-107
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• 2016

Purpose : Cardiovascular disease is major factor of mortality in worldwide. Previous studies shown that the socioeconomic factors, nutrition factors, health behavior factors, biological factors and co-morbidity are increasing a prevalence of cardiovascular disease. Method : This study examined the risk factors for cardiovascular disease among adults aged 30 years and older using the data from the 2012 to 2014 Korean National Health and Nutrition Examination Survey (KNHANES). The study participants were 7,555 Cardiovascular disease includes hypertension, stroke, angina pactoris, and myocardial infarction. Descriptive statistic and multivariates logistic regression were calculated. Result : The overall prevalence of cardiovascular disease was 31.16% in the participants. Cardiovascular disease was significantly associated with gender, age, income, education, marital status as socioeconomic factors in unadjusted model. After adjusting socioeconomic status variables, past smoker (OR 1.27, 95% CI 1.05-1.55), obesity (OR 7.14, 95% CI 4.21-12.11), skipping a meal (OR 2.79, 95% CI 2.46-3.16), HDL-C (OR 0.99, 95% CI 0.98-0.99) and WC (OR 1.06, 95% CI 1.05-1.07) were associated with cardiovascular disease. Conclusion : The results marked the importance of finding high risk groups and an early management of cardiovascular disease.