• 대한이식학회지
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• 제32권4호
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• pp.92-103
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• 2018

Background: Currently, trimethoprim-sulfamethoxazole is used for Pneumocystis jirovecii pneumonia (PJP) prophylaxis, but it is associated with frequent adverse effects. This study evaluated the efficacy and safety of the current protocol and proposes an individualized risk-based prophylaxis protocol. Methods: The PJP incidence and risk factors during the first 6 months (early PJP) and afterwards (late PJP) was assessed in renal transplant recipients with (prophylaxis group) and without (no-prophylaxis group) 6-month PJP prophylaxis. Results: In 578 patients, there were 39 cases of PJP during a median follow-up of 51 months. Renal adverse events were encountered frequently during trimethoprim-sulfamethoxazole prophylaxis, leading to premature discontinuation. Patients without the prophylaxis had a significantly higher incidence of early PJP (n=27, 6.6%) compared to patients with the prophylaxis (n=0). The incidence of late PJP was 2.2%, without between-group differences. The factors associated with early PJP were preoperative desensitization and acute rejection within 1 month, whereas late PJP was associated with age, deceased donor transplant, and acute rejection requiring antithymocyte globulin treatment. Conclusions: Based on the simulation results of several risk-based scenarios, the authors recommend universal prophylaxis up to 6 months post-transplant and extended selective prophylaxis in patients aged ${\geq}57$ years and those with a transplant from deceased donors.

• 분석과학
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• 제28권6호
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• pp.398-408
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• 2015

번개탄과 같은 착화탄을 이용한 일산화탄소 중독사는 국내에서 빈번히 발생하고 있으며, 대부분이 자살과 관련되지만 타살의 가능성을 절대적으로 배제할 수는 없는 실정이다. 때문에 변사자와 사건 현장을 법과학적으로 철저하게 조사하여 변사자가 자살을 실행했다는 것을 입증해야 하며, 착화탄을 사용하여 자살을 했을 경우 착화탄이 접촉될 수 있는 손, 콧속 및 문고리 등에서 착화탄성분을 확인하는 것이 사건현장과 변사자와의 관련성을 입증하는데 매우 중요하다. 착화탄성분은 외관 및 화학적 조성을 토대로 확인할 수 있었으며, 판별분석을 통하여 검출된 착화탄성분이 검정색으로 관찰되는 목편과는 뚜렷하게 구별됨을 확인하였다. 자살을 입증한 사례에서 착화탄성분 분석을 위하여 실체현미경 및 주사형 전자현미경에너지분산형 X-선분석기(SEM-EDX)를 사용하였고, 일부 탄화된 수지상물질의 성분 분석을 위하여 현미경-적외선분광광도계(microscope-FT/IR) 및 열분해-기체크로마토그래프/질량분석기(Py-GC/MS)를 사용하였다. 또한 수면제 약물인 디펜히드라민을 위하여 기체크로마토그래프/질량분석기(GC/MS)를 사용하였고, 혈중 일산화탄소-헤모글로빈(CO-Hb) 농도 확인을 위하여 기체크로마토그래프(GC/TCD)를 사용하였다. 착화탄성분을 외관형상 및 화학적 성분을 토대로 손바닥 및 손잡이 등에서 확인하였으며, 특히 변사자의 콧구멍에서 착화탄성분을 검출함으로써 변사자가 자살을 위해 직접 불을 피웠음을 확인할 수 있었다. 일부 탄화된 검정색물질은 아크릴로니트릴스티렌 수지로 포장용 비닐가방에 널리 사용되는 재질로 착화탄을 운반할 때 사용된 것으로 추정되었다. 수면제 성분으로 디펜히드라민이 2.3 mg/L 검출되었으나 사망사건에서 검출된 농도 8-31 mg/L (평균 16 mg/L) 보다 훨씬 낮은 농도로 단지 수면을 유도했을 것으로 판단되었으며, 79%의 혈중 CO-Hb의 검출은 일산화탄소 중독이 사망원인이었음을 나타내었다. 위에서 언급된 절차들은 밀폐된 방 또는 차량 안에서 착화탄을 피워 사망한 일산화탄소 중독사에서 자살인지를 판단하는데 있어 매우 훌륭한 사례라 할 수 있을 것이다.

• 대한가정학회지
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• 제19권1호
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• pp.47-52
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• 1981

In the view of the fact that data are scare concerning the change of Methionine composition of poultry meat in function of storage temperature and cooking method. The present study was carried out to change in these compounds and the results were summarized as follows. 1. The result of measuring Methionine compound of Raw material stored under the condition of $5^{\circ}C$, $10^{\circ}C$ for 6 weeks were increased as temperature increases. 2. The result of change in Methionine compound of Roasting were deceased than Raw material It was greatly decreased in the storage for 42 days at 1$0^{\circ}C$ and slightly decreased in the storage for 14 days at $5^{\circ}C$. 3. when the Boiling in the water, Methoinine compound was decreased than Roasting to compare with Raw material 4. By the results of this study, one of the best cooking method is Roasting, Because of the change I Methionine compound of Roasting is slightly decrease.

• 한국추진공학회:학술대회논문집
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• 한국추진공학회 2011년도 제37회 추계학술대회논문집
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• pp.228-236
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• 2011

강내탄도의 다양한 해석 모델에 따른 성능 및 내부 유동을 분석하였다. 항력 모델은 초기 내부 유동 특성에 큰 영향을 미치며 고체추진제의 항력이 작을수록 차압의 진동을 감소시키는 것으로 나타났다. Nusselt 수 모델은 강내탄도의 주요 성능에 영향을 미치지 않으며 고체추진제의 열전달이 없는 경우에는 역압력이 발생하지 않는 것으로 나타났다.

• International journal of advanced smart convergence
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• 제11권3호
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• pp.36-41
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• 2022

In the 21st century, information collection and information provision based on digital informatization and intelligent automation are emerging as one of the social problems in the society for the elderly and the vulnerable groups in the welfare society including the disabled, and various methods are being studied to find realistic alternatives. Among these factors, the problem of the elderly living alone is emerging as the most serious, and as a realistic approach to solve some problems by applying information devices, it is a monitoring system using the Internet of Things(IoT). The need for an optimized system is emerging. In this study, the state of the elderly and the elderly living alone can be measured remotely by applying IoT technology. We present the research cases of a Breathing Sensor-based Smart Monitoring System that is used as a smart information system and used as a monitoring system for the elderly and infirm when it is identified as deceased through state detection

• Biotechnology and Bioprocess Engineering:BBE
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• 제6권2호
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• pp.156-156
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• 2001

The objective of this study was to investigate the effects of nutrients and culture conditions on morphology during the seed culture of C. acremonium ATCC 20339 Morphological factors such as hyphal length number of tips number of arthrospores were observed to investigate the relationship between seed morphology and CPC production. During the time course of seed culture, hyphal length was shortened and the number of arthrospores increased rapidly On the other hand the number of tips deceased rapidly and this was closely related to the hyphal length Mixed nitrogen sources of 3% solybean meal and 1% cotton seed flour were determined as the proper organic nitrogen sources, in terms of the morphological factors in the seed culture. This fact was proven in batch culture for the production of Cephalosporin C. It was also found that a proper agitation speed enhanced the morphological differentiation of C. acremonium ATCC 20339, thus improving the production of Cephalosporin C.

• Archives of Pharmacal Research
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• 제16권1호
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• pp.50-56
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• 1993

The microencapsulation of sodium naproxen with Eudragit. RS was studied by coacrtvation/phase separation process using Span 80 in mineral oil/acetone system. Various factors which affect the mciroencapsulation, e.g., stirring speed, and surfactant concentraction, Eudagit RS concentration and loading drug amounts were examined. For the evaluation of the prepared microcapsules, release rate, particle size distribution and surface appearance as well as in vivo test were carried out. The addition of n-hexane and freezing of microcapsules accelerated the hardening of microcapsules. The optimum concentration of Span 80 ti prepare the smallest microcapsules was the same value with the CMC of Span 80 in solvent system. When 1.5% (w/w) Span 80 was used, the smallest microcapsules were formed $(30.02\pm5.05\mu$ in diameter) belonging to the powder category showing smooth, round and uniform surface. The release of sodium naproxen was retarded by microencapsulation with Eudragit RS. The Eudragit RS microcapsules showed significantly increased AUC and MRT and deceased Cl/F in rabbits.

• 복식문화연구
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• 제8권3호
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• pp.374-386
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• 2000

This study investigated the relation between seasonal variation of total clothing weight, room, outdoor temperature and basal metabolic rate in man. The basal metabolic rate and total clothing weight, room temperature was determined seasonal for a period of two years and grouped four seasons. Subjects (adults volunteers) who live in seoul and mokpo were compose 120 subject The results were obtained as follows. Seasonal outdoor temperature was difference of seoul and. mokpo. But room temperature in apartments was a little difference than private house. Total-clothing weight is showed seasonal variations at the seoul, private house than at the mokpo, apartment.. The basal metabolic rate is suggested there in gender difference in the basal metabolic rate (P〈.001). The basal metabolic rate increased gradually with the peak of winter sespectively and deceased again todward summer. The difference of between basal metabolic rate in summer and winter was significant room temperature, of seoul and private house, and light total clothing weight.

• 설비공학논문집
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• 제13권7호
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• pp.579-587
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• 2001

This study investigates particle collection characteristics of a cylindrical electrostatic precipitator. Experimental work has been made for the submicron particles. The effects of polarity of discharge electrode wire, particle diameter, gas velocity, gas temperature, and specific corona power on the particle collection efficiency are investigated. The efficiency of negative corona is higher than that of positive corona. as the particle diameter increases, the efficiency is decreased when the diameter is in the range of 0.02-0.6 micron, but is increased for the nanometer particles with diameter smaller than 0.02 micron. The efficiency is increased with increase of specific corona power. As the gas temperature increases, overall collection efficiency is increased for a negative corona, but is deceased for a positive corona.

• 가정과삶의질연구
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• 제26권5호
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• pp.39-49
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• 2008

This research reports on a qualitative analysis of email facilitated reflective dialogue with seven college students whose parent dies. The study was exploratory in considering cultural values on intact family and asked the question: What do children experience after parental death in terms of the relationships with intra and extrafamily systems? Young adult children of single parent family expressed that they felt social pressure to practice filial piety toward their single parent. They made efforts to fulfill the social expectation and to achieve social desirability. Social stigma from extrafamily systems affected the experiences of the bereaved children. In terms of intrafamily system, young adult children tend to idealize their deceased parent. Single parents depended on the young adult children, which made parent-child relationship enmeshed or conflicting. The holistic view of the study highlights the importance of interactions between individuals and the intra and extra family systems when understanding family loss experience of the bereaved young people.