• Title/Summary/Keyword: the binomial distribution

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Improved Algorithms for the Identification of Yeast Proteins and Significant Transcription Factor and Motif Analysis

  • Lee Seung-Won;Hong Seong-Eui;Lee Kyoo-Yeol;Choi Do-Il;Chung Hae-Young;Hur Cheol-Goo
    • Genomics & Informatics
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    • v.4 no.2
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    • pp.87-93
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    • 2006
  • With the rapid development of MS technologiesy, the demands for a more sophisticated MS interpretation algorithm haves grown as well. We have developed a new protein fingerprinting method using a binomial distribution, (fBIND). With the fBIND, we improved the performance accuracy of protein fingerprinting up to the maximum 49% (more than MOWSE) and 2% than(at a previous binomial distribution approach studied by of Wool et al.) as compared to the established algorithms. Moreover, we also suggest a the statistical approach to define the significance of transcription factors and motifs in the identified proteins based on the Gene Ontology (GO). Abbreviations: fBIND, fingerprinting using binomial distribution; GO, Gene Ontology; MS, Mass Spectrometry; PMF, peptide mass fingerprinting; nr, nonredundant; SGD, Saccharomyces Genome Database

BINOMIAL PROMOTION AND POISSON RECRUITMENT MODEL FOR MANPOWER DEVELOPMENT

  • Etuk, U.H.
    • The Pure and Applied Mathematics
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    • v.4 no.2
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    • pp.105-110
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    • 1997
  • The distribution of staff in a hierachial organization has been studied in a variety of forms and models. Results here show that the promotion process follows a binomial distribution with parameters n and $\alpha=e^{-pt}$ and the recruitment process follows a poisson distribution with parameter $\lambda$. Futhermore, the mean time to promotion in the grade was estimated.

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Approximation of binomial Distribution via Dynamic Graphics

  • Lee, Kee-Won
    • Communications for Statistical Applications and Methods
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    • v.6 no.3
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    • pp.821-830
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    • 1999
  • In This paper we calculate the probabilities of binomial and Poisson distributions when n or${\mu}$ is large. Based on this calculation we consider the normal approximation to the binomial and binomial approximation to Poisson. We implement this approximation via CGI and dynamic graphs. These implementation are made available through the internet.

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Penalized Likelihood Regression with Negative Binomial Data with Unknown Shape Parameter

  • Kim, Young-Ju
    • Communications for Statistical Applications and Methods
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    • v.14 no.1
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    • pp.23-32
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    • 2007
  • We consider penalized likelihood regression with data from the negative binomial distribution with unknown shape parameter. Smoothing parameter selection and asymptotically efficient low dimensional approximations are employed for negative binomial data along with shape parameter estimation through several different algorithms.

Reliability Demonstration Test for a Finite Population Based on the Conjugacy of the Beta-Binomial Distribution (베타-이항분포의 공액성을 근거로 한 유한 모집단의 신뢰성 입증 시험)

  • Jeon, Jong-Seon;Ahn, Sun-Eung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.35 no.2
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    • pp.98-105
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    • 2012
  • This paper describes the Bayesian approach for reliability demonstration test based on the samples from a finite population. The Bayesian approach involves the technical method about how to combine the prior distribution and the likelihood function to produce the posterior distribution. In this paper, the hypergeometric distribution is adopted as a likelihood function for a finite population. The conjugacy of the beta-binomial distribution and the hypergeometric distribution is shown and is used to make a decision about whether to accept or reject the finite population judging from a viewpoint of faulty goods. A numerical example is also given.

Maximum likelihood estimation for a mixture distribution (이항-퇴화 혼합분포의 최우추정법)

  • Hwang, Seonyeong;Sohn, Seung Hye;Oh, Changhyuck
    • Journal of the Korean Data and Information Science Society
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    • v.26 no.2
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    • pp.313-322
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    • 2015
  • A mixture distribution of a discrete uniform or degenerated distribution and two binomial distribution is proposed and a method of obtaining the maximum likelihood estimates of the parameters is provided. For the proposed model simulation studies were conducted to see performance of the maximum likelihood estimates and a mixture of a degenerated distribution and two binomial distributions was applied to fit a lecture evaluation data to show a good result.

Krawtchouk Polynomial Approximation for Binomial Convolutions

  • Ha, Hyung-Tae
    • Kyungpook Mathematical Journal
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    • v.57 no.3
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    • pp.493-502
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    • 2017
  • We propose an accurate approximation method via discrete Krawtchouk orthogonal polynomials to the distribution of a sum of independent but non-identically distributed binomial random variables. This approximation is a weighted binomial distribution with no need for continuity correction unlike commonly used density approximation methods such as saddlepoint, Gram-Charlier A type(GC), and Gaussian approximation methods. The accuracy obtained from the proposed approximation is compared with saddlepoint approximations applied by Eisinga et al. [4], which are the most accurate method among higher order asymptotic approximation methods. The numerical results show that the proposed approximation in general provide more accurate estimates over the entire range for the target probability mass function including the right-tail probabilities. In addition, the method is mathematically tractable and computationally easy to program.

The Binomial Distribution with Fuzzy Valued Probability (퍼지 확률에 의한 이항분포)

  • Gang, Man-Gi;Seo, Hyeon-A;Park, Yeong-Rae;Choe, Gyu-Tak
    • Proceedings of the Korean Institute of Intelligent Systems Conference
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    • 2008.04a
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    • pp.33-36
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    • 2008
  • We introduce some properties for fuzzy binomial distributions with fuzzy valued probability. First we define fuzzy type I error and type II error for fuzzy relative frequency and agreement index. And we show that an fuzzy power function and fuzzy binomial frequency function for binomial proportion test.

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Development of Accident Prediction Models for Freeway Interchange Ramps (고속도로 인터체인지 연결로에서의 교통사고 예측모형 개발)

  • Park, Hyo-Sin;Son, Bong-Su;Kim, Hyeong-Jin
    • Journal of Korean Society of Transportation
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    • v.25 no.3
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    • pp.123-135
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    • 2007
  • The objective of this study is to analyze the relationship between traffic accidents occurring at trumpet interchange ramps according to accident type as well as the relevant factors that led to the traffic accidents, such as geometric design elements and traffic volumes. In the process of analysis of the distribution of traffic accidents, negative binomial distribution was selected as the most appropriate model. Negative binomial regression models were developed for total trumpet interchange ramps, direct ramps, loop ramps and semi-direct ramps based on the negative binomial distribution. Based upon several statistical diagnostics of the difference between observed accidents and predicted accidents with four previously developed models, the fit proved to be reasonable. Understanding of statistically significant variables in the developed model will enable designers to increase efficiency in terms of road operations and the development of traffic accident prevention policies in accordance with road design features.

ESTIMATING THE SIMULTANEOUS CONFIDENCE LEVELS FOR THE DIFFERENCE OF PROPORTIONS FROM MULTIVARIATE BINOMIAL DISTRIBUTIONS

  • Jeong, Hyeong-Chul;Jhun, Myoung-Shic;Lee, Jae-Won
    • Journal of the Korean Statistical Society
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    • v.36 no.3
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    • pp.397-410
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    • 2007
  • For the two groups data from multivariate binomial distribution, we consider a bootstrap approach to inferring the simultaneous confidence level and its standard error of a collection of the dependent confidence intervals for the difference of proportions with an experimentwise error rate at the a level are presented. The bootstrap method is used to estimate the simultaneous confidence probability for the difference of proportions.