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Alteration in Leukocyte Subsets and Expressions of FcγR and Complement Receptors among Female Ragpickers in Eastern India

  • Mondal, Nandan K.;Siddique, Shabana;Banerjee, Madhuchanda;Roychoudhury, Sanghita;Mukherjee, Sayali;Slaughter, Mark S.;Lahiri, Twisha;Ray, Manas R.
    • Safety and Health at Work
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    • v.8 no.2
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    • pp.198-205
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    • 2017
  • Background: There are a million ragpickers in India who gather and trade recyclable municipal solid wastes materials for a living. The objective of this study was to examine whether their occupation adversely affects their immunity. Methods: Seventy-four women ragpickers (median age, 30 years) and 65 age-matched control housemaids were enrolled. Flow cytometry was used to measure leukocyte subsets, and leukocyte expressions of $Fc{\gamma}$ receptor I (CD64), $Fc{\gamma}RIII$ (CD16), complement receptor 1 (CD35) and CR3 (CD11b/CD18), and CD14. Serum total immunoglobulin-E was estimated with enzyme-linked immunosorbent assay. Results: Compared with the controls, ragpickers had significantly (p < 0.0001) higher levels of CD8-T-cytotoxic, CD16+CD56+natural killer, and CD4+CD45RO+memory T-cells, but depleted levels of CD19+B-cells. The percentage of CD4+T-helper-cells was lower than the control group (p < 0.0001), but their absolute number was relatively unchanged (p = 0.42) due to 11% higher lymphocyte counts in ragpickers. In ragpickers, the percentages of CD14+CD16+intermediate and CD14dim CD16+nonclassical monocyte subsets were elevated with a decline in CD14+CD16-classical monocytes. The expressions of CD64, CD16, CD35, and CD11b/CD18 on both monocytes and neutrophils, and CD14 on monocytes were significantly higher in ragpickers. In addition, ragpickers had 2.7-times more serum immunoglobulin-E than the controls (p < 0.0001). After controlling potential confounders, the profession of ragpicking was positively associated with the changes. Conclusion: Ragpicking is associated with alterations in both innate (neutrophils, monocytes, and natural killer cell numbers and expression of complement and $Fc{\gamma}$ receptors) and adaptive immunity (numbers of circulating B cells, helper, cytotoxic, and memory T cells).

Antioxidative and Nitrite Scavenging Activities of Polygonatum odoratum Root Extracts with Different Steaming and Roasting Conditions (둥굴레 근경의 증자 및 볶음조건에 따른 추출물의 항산화성 및 아질산염 소거능 변화)

  • Kim Kyung-Tae;Kim Jung-Ok;Lee Gee-Dong;Kwon Joong-Ho
    • Food Science and Preservation
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    • v.12 no.2
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    • pp.166-172
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    • 2005
  • Response surface methodology (RSM) was applied to monitor the effects of steaming and roasting conditions of Polygonatum odoratum roots an total phenolics content, electron donating ability (EDA) and nitrite-scavenging ability (NSA) of the extract. In steaming and roasting processes based on the central composite design. with variations in steaming time $(60\~180\;min)$, roasting temperature $(110\~150\;min)$ and roasting time $(10\~50\;min)$, coefficients of determinations $(R^2)$ were 0.9356 (p<0.01) in total phenolics, 0.9578 (p<0.01) in EDA and 0.9436 (p<0.01) in NSA (pH 3.0). The maximum value of total phenolics was $2847.67\;mg\%$ at 135.59 min of steaming time, $143.84^{\circ}C$ of roasting temperature and 43.47 min of roasting time. The maximum value of EDA was $75.00\%$ in 108.98 min, $135.56^{\circ}C$ and 48.86 min. The maximum value of NSA (pH 3.0) was $87.38\%$ in 162.80 min, $143.88^{\circ}C$ and 31.97 min, respectively. Total phenolics content of the extract was influenced by heating conditions in the order of roasting temperature, steaming time and roasting time. While EDA and NSA were appreciably influenced by roasting time, followed by roasting temperature and steaming time.

A Development of the Evaluation Index for UTIS Traffic Information Service (UTIS 교통정보 제공서비스 성과평가 인덱스 개발)

  • Kim, Eun-Jeong;Bae, Kwang-Soo;Ahn, Gye-Hyeong;Lee, Chul-Ki
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.9 no.6
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    • pp.13-21
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    • 2010
  • Road Traffic Authority and National Police Agency is currently managing the "development of an integrated metropolitan traffic information infrastructure" that installs of facilities for a traffic information infrastructures, such as Local Traffic Information Center, UTIS(Urban Traffic Information System), CCTV, VMS and etc. CTIC was established in 2005 to act as an traffic information hub and to provide integrated UTIS traffic information without regional barriers. This study was carried out to seek for solution to improve quality of UTIS traffic information service for the Central Traffic Information Center(CTIC). In this study, the Evaluation index for UTIS traffic information service was developed and the implementation plan was established by using requirement analysis method, case study and AHP(Analytic Hierarchy Process) technique. The Evaluation index consist of 5 fields and 20 index, it make possible evaluation of direct/indirect effect for UTIS traffic information service. In conclusion, It is expected that quality of UTIS traffic information service will be improved by using developed evaluation index and also can be applied for performance evaluation of other traffic information systems.

Deposition uniformity of 7 wt% YSZ as a thermal barrier coating with different configurational arrangement for turbine blade shape mock-up by electron beam physical vapor deposition (터빈블레이드 형상 mock-up의 기하학적 배치조건에 따른 전자빔 물리기상증착법으로 제조된 7 wt% YSZ 열차폐 코팅의 코팅 균일성)

  • Oh, Yoon-Suk;Chae, Jung-Min;Ryu, Ho-lim;Han, Yoon-Soo;An, Jong-Kee;Son, Myung-Sook;Kim, Hong-Kyu
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.29 no.6
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    • pp.308-316
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    • 2019
  • Electron beam physical vapor deposition (EBPVD) is a conventional method to fabricate thermal barrier coating (TBC) of high temperature airfoil engine parts, such as blade etc. for its high temperature structural stability from the nature of columnar growth behavior. For the high quality of TBC by EBPVD, the structural factors, such as growth behavior, thickness uniformity and so on, should be managed to obtain the coating which satisfied the required specifications of usable level of mechanical and thermal properties. In this study, the growth behavior and structure variations of 7YSZ (7 wt% yttria stabilized zirconia) coatings with different configurational deposition parameters for the specimens which have turbine blade shape mock-up were investigated. Growth behavior of coatings were studied by comparing computational modeling of evaporation behavior with actual deposition process using e-beam source.

Analysis of Target Identification Performances Using Bistatic ISAR Images (바이스태틱 ISAR 영상을 이용한 표적식별 성능 분석)

  • Lee, Seung-Jae;Lee, Seong-Hyeon;Kang, Min-Seok;Yang, Eunjung;Kim, Kyung-Tae
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.27 no.6
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    • pp.566-576
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    • 2016
  • Inverse synthetic aperture radar(ISAR) image generated from bistatic radar(Bi-ISAR) represents two-dimensional scattering distribution of a target, and the Bi-ISAR can be used for bistatic target identification. However, Bi-ISAR has large variability in scattering mechanisms depending on bistatic configurations and do not represent exact range-Doppler information of a target due to inherent distortion. Thus, an efficient training DB construction is the most important factor in target identification using Bi-ISARs. Recently, a database construction method based on realistic flight scenarios of a target, which provides a reliable identification performance for the monostatic target identification, was applied to target identification using high resolution range profiles(HRRPs) generated from bistatic radar(Bi-HRRPs), to construct efficient training DB under bistatic configurations. Consequently, high identification performance was achieved using only small amount of training Bi-HRRPs, when the target is a considerable distance away from the bistatic radar. Thus, flight scenarios based training DB construction is applied to target identification using Bi-ISARs. Then, the capability and efficiency of the method is analyzed.

A study on the Introduction Plans of Forest Land Bank System (산지은행제도의 도입방안에 관한 연구)

  • Kim, Jong-ho;Kim, Won Kyung;Kwon, Soon-duk
    • Journal of Korean Society of Forest Science
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    • v.104 no.3
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    • pp.503-511
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    • 2015
  • The purpose of this study is to suggest the introduction plans of forest land bank system for effective forestry management as well as the livelihood stability support of aged forest landowners. It is expected that forest land bank system can contribute to solve forestry management problems caused by small and scattered forest lands, aging forest landowners, and the increase of absentee forest landowners. This study examined an existing related case of Farmland Bank system, and suggested basic directions, main functions, priority, and agency for forest land bank system. The goals of forest land bank system include activating private forest land management, improving forest management scale, and supporting stable forestry income. Based on the examination of this study, main projects of forest land bank involve forest land sale and lease consignment, forest land reverse mortgage, forest land scale improvement project, and forest business recovery support program. In addition, this study discussed potential problems and their solutions in introducing and operating the forest land bank system. This study can play a key role to determine a basic direction and to establish policies of the forest land management.

The study of Health Care Utilization and Direct Medical Cost in the Diabetes Mellitus Client (당뇨병 질환자의 의료이용 및 직접의료비 연구)

  • Yoo, In Sook
    • The Journal of the Convergence on Culture Technology
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    • v.1 no.4
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    • pp.87-101
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    • 2015
  • This study was aimed to make data how much spent money of medical utilization and direct medical cost. In order to research we were using Korea Health panel 2012 Statistics which data contained Diabetes mellitus client 812 people in age 19. The method of this study was emergency cost, admission medical cost, out patient department cost(client own due, National Health insurance service due, not insurance fee). The result of this study, Diabete Mellitus client were using 198 times during 1 year per 100, total medical direct cost were 859,942 won, 447,359 won, 363,255,508. And admission times were 5.6 times per year, total direct cost was 772,240 won, 4,061,982 won, and 3,298,329,384 won, and out patient clinic using number was 10 times, medical cost total direct cost containing total direct cost was 11,978 won, 26,020 won, and 21,129,240 won. From this research we conclusion that the occurrence of diabetes mellitus can be increased medical cost and direct medical cost and it can be huge burden to client including their family and quality of life in the future. We suggest that in order to prevention and management of diabetes mellitus healthy diet, activity, blood sugar, and blood management should be encouragement.

An Experimental Study on the Hysteresis Behavior of WUF-B Beam-Column Connection using SN Steel (건축구조용강재(SN490) 조립 H형강 기둥-보 접합부의 이력거동에 관한 실험적 연구)

  • Kim, Sun Hee;Lee, Seong Hui;Kim, Jin Ho;Kim, Dae Jung;Choi, Sung Mo
    • Journal of Korean Society of Steel Construction
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    • v.20 no.6
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    • pp.807-815
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    • 2008
  • The brittle failure where is occurred the welding position of column-beam flange of WUF-B connection that consider about a seismic detail possess a superior ductility capacity before Northridge earthquake 1994, require newly study about WUF-B connection. SAC Steel Project suggests a seismic detail to FEMA-350 by supporting of FEMA. It revise shape of weld access holes of WUF-B connection, welding processand welding material etc, In spite of these revision, AISC Seismic Provisions (2005) prescribe WUF-B connection using an only OMF. Recently in Korea, as the earthquake of about seismic intensity 5 occur, the necessity of revision for connection seismic detail comes to the front in Korea and FEMA-350 connection seismic details are going to include in KBC-2008 as it is. In this study, two column-beam connection specimens were marked by using SM490, SN490 built-up H-section, and based on WUF-B detail prescription of FEMA350. The parameters of the specimens are types of steel (SM, SN), and evaluate the capacities of structure and seismic by experiment. Finally we confirm a superior ductility capacity aboutspecimens JB-1 and JB-2, using SM490 and SN490,and these specimens had sufficient OMF and SMF seismic capacity, as indicated in AISC Seismic Provisions (2005).

Resilience to Burnout and Work Satisfaction of Hospice Volunteers (호스피스자원봉사자의 소진탄력성과 활동만족도)

  • Choi, Soon-Ock
    • Journal of Hospice and Palliative Care
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    • v.12 no.3
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    • pp.147-156
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    • 2009
  • The purpose of this study was to assess the level of resilience to burnout and work satisfaction of hospice volunteers. Methods: Participants included 235 regular volunteers at hospice facilities of two university hospitals and four general hospitals located in Busan. The study instruments were the scale of resilience to burnout and work satisfaction. The scale of resilience to burnout consisted of six dimensions (professional competency, accomplishment and worthiness, firm belief and value about their profession, good teamwork, support by their agency, and individual resources) and 31 items which were rated on a 5-point Likert scale, whereas the scale of work satisfaction consisted of 6 items which were rated on a 5-point Likert scale. Data were analyzed by descriptive statistics, t-test, ANOVA, Tukey and Pearson's correlation coefficient. Results: The mean score of resilience to burnout and work satisfaction of participants were 3.59 and 3.69, respectively. The highest and lowest scores of resilience to burnout were individual resources (3.81) and accomplishment and worthiness (3.36). There were significant differences in resilience to burnout scores, depending on religion, health status, type of hospice facilities, and period of volunteer experience. There were significant differences in work satisfaction scores, depending on gender, religion, education level, health status, and type of hospice facilities. Conclusions: Continuous education and efficient management need to be developed to improve the level of resilience to burnout and work satisfaction of hospice volunteers.

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Monitoring of viruses in cultured walleye pollock Gadus chalcogrammmus (양성 중인 명태(Gadus chalcogrammus)의 바이러스 모니터링)

  • Nam, U-Hwa;Jeon, Chan-Hyeok;Seo, Hyun-Joon;Choi, Da-Young;Seo, Joo-young;Kwon, O-Nam;Kim, Wi-Sik;Kim, Jeong-Ho
    • Journal of fish pathology
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    • v.30 no.1
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    • pp.1-9
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    • 2017
  • This study was conducted to monitor the prevalence of viral hemorrhagic septicemia virus (VHSV), nervous necrosis virus (NNV) and marine birnavirus (MABV) in cultured walleye pollock Gadus chalcogrammus by RT-PCR. All of the viruses tested were not detected by one-step PCR in 62 spleen sample sets, except for NNV in one brain sample set (1/55). By two-step PCR, VHSV was detected in 51.6%(32/62) and NNV was detected in 1.6%(1/62) spleen sample set, but MABV was not detected. In the brain sample sets, the detection rate of NNV was 3.6%(2/55). VHSV and NNV were detected for the first time in cultured walleye pollock in this study. However, the titers of viruses in these sample sets are thought to be very low, because most of the positive sample sets were detected by two-step PCR and none of the fish showed any clinical symptoms of each virus. Continuous monitoring, subsequent virus isolation and validation of carrier fish will be necessary.