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Studies on the evaluation of efficacy of functional cosmetics (I) -Studies on the in vitro SPF test method of sunscreen products

  • Son, Kyung-Hun;Kim, Young-Ok;Lee, Jeong-Pyo;Yang, Seong-Jun;Paek, Ock-Jin;Kim, Won-Hee;Kim, Chong-Kap;Heo, Moon-Young;Choi, Sang-Sook
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.404.2-404.2
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    • 2002

  • The present study was undertaken to develop the in vitro sun protection factor(SPF) test method having good correlation with in vivo method using human. 8% homomentyl salicylate. P3 reference standard and commercially available sunscreen products were measured by the in vitro method using SPF 290S analyzer. and the SPFs were compared with the SPFs measured by in vivo test method. In vitro SPFs of 8% HMS and P3 reference standard were 4.59$\pm$0.12 and 14.94$\pm$0.83. (omitted)

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Studies on Oral Toxicity of Eumcheonyijin-tang in Rats (음천이진탕의 안정성에 관한 실험적 연구)

  • 김영미;최해윤;김종대
    • The Journal of Korean Medicine
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    • v.21 no.3
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    • pp.199-208
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    • 2000

  • Objectives : In order to investigate the toxicity of rats after oral administration of Eumcheonyijin-tang extract. Methods : The experimental animals were subdivided into control, short term administration group, and long term administration group. With changes of gross appearance, the histological changes of liver and kidney were observed. Blood chemical indexes used in this study were AST, ALT, total bilirubin, albumin, BUN and creatinine in serum. Results : In the long term administration group, histological changes were detected in the liver as centrolobular disposition of fatty tissue(adipose cell), and in serum test, AST, ALT increased at 21 days after administration group, serum total bilirubin were increased 21, 28 and 35 days after administration group. So it seems to induce toxicity. Kidneys of the long term administration group revealed histological changes : increasing of connective tissue and pyknosis of glomerulus cell were observed at 28 days after administration group, and in serum test, significant changes of albumin, BUN, and creatinine were admitted. So it seems to induce toxicity. Conclusions : In long term administration of Eumcheonyijin-tang toxicity was induced.

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A study on the evaluation of artificial cartilage using synthetic biodegradable polymers

  • Oh, Ho-Jung;Lee, Nam-Kyung;Kim, Soon-Nam;Hong, Choong-Man;Lee, Ki-Hong;Yoo, Si-Hyung;Shin, In-Soo;Lim, Jae-Hyun;Choi, Seung-Eun
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.100.1-100.1
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    • 2003

  • Tissue engineering has arisen to address the extreme shortage of tissues and organs for transplantation and repair. One of the most successful techniques has been the seeding and culturing cells on three-dimensional biodegradable scaffolds in vitro followed by implantaion in vivo. We used PLA and PLGA as biodegradable polymers and rabbit chondrocytes were isolated and applied to PLA and PLGA to make artificial cartilage. To evaluate the biocompatibility and biological safety of polymers, in vitro cytotoxicity and in vivo animal tests were investigated. (omitted)

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Effects of Cordyceps militaris Mycelia(CMM) oral administration and herbal acupuncture at BL13, LU4 on asthma induced by ovalbumin in rats (동충하초(冬蟲夏草) 약침(藥鍼)과 구강투여(口腔投與)가 Ovalbumin으로 유발된 Asthma에 미치는 영향)

  • Kim, Jae-Hong;Cho, Myung-Rae;Ryu, Choong-Ryul;Chae, Woo-Suk
    • Journal of Acupuncture Research
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    • v.19 no.2
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    • pp.39-50
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    • 2002

  • Objective : The aim of this study was to investigate the effect of CMM oral administration and herbal acupuncture at BL13 LU4 on Asthma induced by ovalbumin in rats Methods : Several experimental items were measured and compared each other ; that is body weight change, oxygen consumption rate, Albumin change, white blood corpuscle change, Erythrocyte change, IgE change. Results : 1. Body weight was significantly increased in herbal acupuncture group after its administration while there was no such a response in oral administration group. 2. Oxygen Consumption rate was significantly increased in oral administration group and herbal acupuncture group. 3. Albumin in serum was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 4. White blood corpuscle in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 5. Erythrocyte in blood was significantly increased in oral administration group after its administration while there was no such a response in herbal acupuncture group. 6. IgE in blood was decreased in oral administration group and herbal acupuncture group but there was no significance in oral administration group and herbal acupuncture group. Conclusion : Based on the above results it is assumed that CMM oral administration and CMM herbal acupuncture can help the treatment of Asthma induced by ovalbumin in rats.

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