• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.3
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• pp.274-287
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• 2016

Objectives: The purpose of this study is to report the effectiveness of Sihochunggan-tang gagambang and Sunbangpaedok-tang gagambang in the five patients with nummular eczema.Methods: This case study was conducted for five nummular eczema patients who have visited Korean Medicine Clinic. Sihochunggan-tang gagambang Sunbangpaedok-tang gagambang was prescribed to all five patients and evaluated the symptom change through photographs and an assessment method. We used Visual Analogue Scale(VAS) as the assessment method.Results & Conclusions: After the treatment, the grade of VAS was decreased and most symptoms of five patients were improved. As a result of examining VAS scores and photographs, Sihochunggan-Tang gagambang and Sunbangpaedok-tang gagambang can be effective on the nummular eczema in five cases in our study.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.1
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• pp.160-168
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• 2015

Objective : The purpose of this study is to report the effect of Gagamhwanggeum-tang on emotional facial flush. Methods : This case study was done on 3 Facial Flush patients who have visited Korean Medicine Clinic. Gagamhwanggeum-tang was prescribed to all 3 patients and evaluated the symptom change through photographs and questionnaire. Investigator's Global Assessment(IGA) was used to evaluate the objective symptom and Visual Analogue Scale(VAS) was used to evaluate the subjective change Results & Conclusion : The IGA and VAS were decreased in 3 patients in our study. Most symptoms of 3 patients were improved. As a result of examining IGA, VAS scores and photographs, Gagamhwanggeum-tang can be effective on emotional facial flush in 3 case in our study.

• The Journal of Korean Medicine
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• v.29 no.4
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• pp.1-12
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• 2008

Background and Objectives: Sinusitis is a common disease in the otorhinolaryngology field. It is inflammatory change of the mucous membrane which surrounds the sinus. The aim of this study was to investigate the anti-inflammatory effects of the Taklisodok-eum (TSE) extract on the mouse model with acute sinusitis induced by S. pneumoniae. Methods: Thirty six-week-old male BALB/c mice were divided into three groups: the normal group, the group inoculated with S. pneumoniae which caused allergic rhinitis (control group), and the group treated with the TSE extract after it was treated the same as the control group (sample group). Results: $NF-{\kappa}B$ activation was suppressed, and iNOS & COX-2 production were inhibited by TSE in acute sinusitis. Apoptosis was increased by TSE in acute sinusitis. The number of eosinophils in the sample group noticeably decreased when compared to the control group. In the general morphologic change, the increase of damaged respiratory ciliated epithelia & eosinophils' infiltration was lessin the sample group. Goblet cells were maintained in the sample group. MMP-9, HSP-70 and BrdU decreased in the sample group. Apocrine secretion decreased in the sample group. Conclusion: The findings in this study show that TSE reduces acute sinusitis through its anti-inflammatory effects, such as the inhibition of $NF-{\kappa}B$ activity.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.340-348
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• 1997

The glaucoma, cataract and causing-blindness-diseases have high clinical importance by their severity of the symptoms and possibility of causing visual loss. Glaucoma is caused by an increase in the intraocular pressure, if severe enough, can cause field loss and eventually complete blindness. In cataract, the general clarity of vision is impaired due to a loss of transparency of the chrystalline lens of the eye. The causing-blindness-diseases can be divided to PokMaeng which cause sudden blindness and ChungMaeng, in which visual acuity is losed gradually. In glaucoma, cataract and causing-blindness-diseases, the visual acuity is affected and the patient may complain blurriness, fatigue of eye, visual field loss deficiency or scintillant feeling, vitreous floaters. In this study, 32 patients who have cataract, glaucoma or other causing-blindness-diseases was treated with oriental medicine or acupuncture from July, l996 to May. 1997, and was followed up by their symptoms and visual acuity. 1. In glaucoma patients, intraocular pressure decreased significantry and the symptoms improved positively. 2. In cataract patients, there was no improvement of visual acuity but $40\%$ of patients found their symptoms improved. 3. In causing-blindness-diseases, $57\%$ of patients reported improvement of their symptoms such as blurriness or fatigue of eye. 4. Through oriental medical treatment, the symptoms of glaucoma, cataract and causing-blindness-diseases can be treated effectively. Therefore oriental management seems to be possible to cure glaucoma, cataract and causing-blindness-diseases.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.21 no.2
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• pp.102-111
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• 2008

Background : The purpose of this study is to make the oriental medicine treatment useful and develop the way of acne cure. Object&Metbod : This study is based on analysis of Recent paper about Oriental medicine of acne, mainly for the external treatment. Results: We analyzed recent treatis about acne cure with external treatment in clinical and analytic study. For the first, there are various clinical approaches with: single use of external treatment, external treatment and herb medicine methods and acidic ionized water. The others are about practical applications on the external treatment, and traditional chinese medical approaches. Conclusion: To develop the better medical care on acne, development and verifications of various treatment methods are necessary on the basis of the merits of oriental treatment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.19 no.2
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• pp.192-201
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• 2006

Objectives : Recently, He-Ne laser has been used for clinical purpose. We study the medical basis of He-Ne laser therapy and We make a proposal concerning the clinical application of using He-Ne laser in Medicine. Methods : We have selected data related to He-Ne laser therapy and study how to use He-Ne laser in clinic. Results : In biology, He-Ne laser therapy has been effects of an improve in skin regeneration an improve in peripheral and central nerve regeneration an improve in muscle regeneration, an anti-inflammation an alleviation of pain and a bone repair. In oriental medicine, He-Ne laser has been used to laser acupuncture and laser oriental physical treatment. In clinic, He-Ne laser have been used to care several parts like as facial palsy, facial spasm, trigeminal neuropathy, rhinitis and tinnitus. Recently, there is argument that He-Ne laser therapy is suitable to medical insurance. Conclusions : Laser therapy in oriental medicine is widespread and We can apply He-Ne laser to facial palsy, facial spasm, trigeminal neuropathy, rhinitis, tinnitus by using laser acupuncture or laser oriental physical treatment. Till now the whole mechanisms are not fully understood, so we hope to study these mechanisms actively and make suitable to medical insurance device in the near future.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.10 no.1
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• pp.357-366
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• 1997

Urticaria is an erythematous or white non-pitting edematous plague that changes in size and shape by peripheral extention or regression during the few hours or days. Urticaria is classified as acute or chronic type. The etiology of acute urticaria has been determined in many case, but the cause of chronic urticaria has been determined in only $5\%\;to\;20\%$ of cases. This observation was aimed to evaluate the clinical manifestations and clinical indence of urticaria seen between June, 1995 and November, 1996(18months) at the Department of Dermatology, Oriental Medical Hospital, Kyung Hee University. The results were summarized as follows ; 1. In the cases of 106 patients, $43\%\;were\;male\;and\;51\%$ were female. 2. The pick incidence of age group was 20 to 29($32\%$). 3. The most frequent duration of urticaria was from 2 months to 6 months. 4. In this study, the inciting causes could not be found in $61\%\;of\;acute\;patients,\;60\%$ of chronic patients. 5. Among 107 patients, $5\%$ of all patients had personal history of atopic diseases and $9\%$ of all patients had familly history. 6. Angioedema was founded in 7 patients, and the most common involved site were lips, eyelids and tongue. 7. The most frequently treated prescription was Chhunggisan which occupied $51\%$ of all, Gyakhangjunggisan(41\%$) and Gosamhomasan($25\%$), Bangpoongtongsungsan($22\%$) in that order of frequency.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.61-77
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• 2016

목적: 본 연구에서는 TJ 열수추출물이 아토피 피부염에 미치는 효과를 확인하고자 하였다. 방법: 2, 4-dinitrochlorobenzen (DNCB)으로 BALB/c 마우스에 1차 감작 후 3주간 2차 감작을 시행하여 아토피 유사 피부병변을 나타내는 접촉성 피부염을 유발한 뒤 동결건조 처리된 TJ 분말을 (PBS/EtOH/Cremophor=6:1:3)에 용해시켜 쥐의 등 피부에 10, 50 mg/ml 농도로 3주간 도포하였다. 결과: TJ 열수추출물은 아토피 피부 병변의 염증세포 침윤을 억제하였고 (10, 50 mg/ml ) 표피와 진피 두께를 회복시켰으며 (10, 50 mg/ml ), 혈청에서 히스타민 방출을 억제하였다 (00 mg/ml ). 또한 Th2 세포와 관련된 cytokine인 interleukin (IL)-4, IL-5, IL-13과 thymic stromal lymphopoietin (TSLP)의 mRNA 발현 양을 감소시켰고 (10, 50 mg/ml ), Th2 chemokine인 thymus- and activation-regulated chemokine (TARC or CCL17)의 mRNA의 발현 양을 감소시켰다 (10, 50 mg/ml ). 결론: TJ 열수추출물을 BALB/c 마우스에 외용하였을 때 항아토피 효과가 있음을 확인하였으며 따라서 TJ가 아토피 피부염 치료의 외용제로 활용될 수 있을 것으로 사료된다.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.33 no.4
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• pp.55-73
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• 2020

Objectives : We investigated the effectiveness and safety of intranasal phototherapy for allergic rhinitis (AR). Methods : We searched 8 electronic databases (PubMed, Cochrane Library, CNKI, CiNii Articles, OASIS, NDSL, KISS, KMbase) to identify randomized controlled trials (RCTs) that reported the use of intranasal phototherapy for AR from their inception until May 30, 2020. Two investigators independently searched, collected, and screened the RCTs. We performed data extraction and evaluation for risk of bias using the Cochrane risk-of-bias tool. Results : This study included 12 RCTs; six studies compared intranasal and sham phototherapy, of which four studies reported a significant inter group difference and two studies reported a significant difference partially. No significant changes in symptoms were observed between the phototherapy and conventional therapy groups. The phototherapy and concurrent acupuncture treatment group showed a significantly higher effectiveness rate compared with the group that received only acupuncture. Both the phototherapy and laser acupuncture group showed significant improvement in the symptom severity scale scores. Six studies reported mild adverse effects, such as dryness and nasal pain in the intranasal phototherapy group; however, no severe adverse effects were reported. Conclusions : This study confirmed the safety and effectiveness of intranasal phototherapy for symptom relief and improved quality of life in patients with AR. However, further studies are needed on this topic in order to demonstrate it clearly.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.30 no.4
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• pp.75-96
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• 2017

Objectives : The purpose of this study was to investigate the treatment trend for allergic rhinitis in Korean Medicine. Methods : We conducted an online survey for Korean Medicine Doctors who were registered in the association of Korean Medicine. The questionnaire was consisted of patient characteristics, diagnosis status, treatment status, and future research needs. Results : Data from total of 396 respondents were analyzed. More than 70% of the patient came to the Korean Medicine Clinic after visiting the Western Medicine Clinic in 43.9% of the respondents. 55.6% of the respondents performed combination therapy. History taking, nasal examination, x-ray, and Korean Medicine diagnostic test were used for diagnosis. The mean duration of treatment ranged from $4.9{\pm}2.91$ to $15.2{\pm}8.45$ for pediatric and early childhood patients and from $17.5{\pm}16.15$ to $5.3{\pm}3.85$ weeks for adolescents and adult patients. The mean number of treatment times was from $9.8{\pm}7.00$ to $33.5{\pm}24.45$ for pediatric and early childhood patients and from $10.8{\pm}11.55$ to $40.4{\pm}48.18$ times for adolescents and adult patients. 64.5%, 48.0%, and 91.2% of the respondents used herbal medication in national health insurance coverage, herbal medication uninsured in health insurance and herbal prescription filled at each medical institution, respectively for pediatric and early childhood patients and 67.6%, 42.8% and 86.1% for adolescents and adult patients. 36.9% and 36.4% of respondents answered that the study of acupuncture and herbal medicine are needed preferentially. Conclusions : The results of this survey will be used to develop clinical practice guideline that reflect actual clinical practice.