• Clinical and Experimental Pediatrics
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• v.46 no.2
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• pp.167-172
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• 2003

Purpose : Pulmonary vascular hypertension is a common problem in congenital heart disease, the most common cardiac condition in childhood. However, the mechanisms responsible for this pathologic change, treatment, and prevention are poorly understood. Therefore, we studied the gene expression of vascular endothelial growth factor(VEGF) by using a hypoxic model of the pulmonary artery smooth muscle cells. Methods : The main pulmonary artery and its proximal branches of a 6 wk old Fischer rat were excised. They were cut into multiple small pieces and suspended in DMEM medium supplemented with 20% fetal bovine serum and incubated in 5% $CO_2$-95% air atmosphere. The smooth muscle cells were confirmed by immunostaining with smooth muscle myosin and ${\alpha}$-smooth muscle actin antibodies. The VEGF gene expression in the hypoxic group was compared with the one in control the group as well as the one in the starved group by RT-PCR and Northern blot hybridization. Results : There was no statistically significant difference among the control, hypoxic and starved groups. Conclusion : There are few studies of pulmonary vascular hypertension at the molecular level in Korea. Therefore, we studied the expression of VEGF gene in hypoxic pulmonary vascular smooth muscle cells. Further studies will be needed to find the difference between newly born and adult rats, or human and rat pulmonary vascular smooth muscle cells in gene expression. We hope that the study will lead to a better understanding of pulmonary vascular hypertension.

• Journal of Environmental Science International
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• v.29 no.10
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• pp.989-996
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• 2020

This study was conducted to determine the effect of low temperature and low radiation conditions on the yield and quality of hot pepper at an early growth stage in Korea. In plastic greenhouses, low temperature, low temperature with covered shading treatments were set 17 to 42 days after transplanting. The pepper growing degree days decreased by 5.5% due to the low temperature during the treatment period. Radiation decreased by 74.7% due to the covered shading. After commencing treatments, pepper plant growth decreased with low temperature and low radiation. Analysis of the yield showed that the first harvest was delayed by low radiation. The cumulative yields of 119 days after transplanting were 1,956, 2,171, and 2,018 g/㎡ for control, low temperature, and low temperature with low radiation respectively. Capsaicin and dihydrocapsaicin concentrations in pepper fruit decreased with low temperature and low radiation. To investigate the photosynthetic characteristics according to the treatment, the carbon dioxide reaction curve was analyzed using the biochemical model of photosynthesis. Results showed that the maximum photosynthetic rate, V_cmax (maximum carboxylation rate), J (electric transportation rate), and TPU (triose phosphate utilization) decreased at low temperatures; the maximum photosynthetic rate, J, and g_m (dark respiration rate) were reduced by shading. These results indicate that low temperature and low radiation can retard early growth, yield, and quality, but these can also be recovered 119 days after planting. Based on the results, the yield and quality of pepper can recover from abiotic stresses with proper cultivation.

• KIPS Transactions on Software and Data Engineering
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• v.9 no.4
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• pp.129-136
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• 2020

PM2.5 which is a very tiny air particulate matter even smaller than PM10 has been issued in the environmental problem. Since PM2.5 can cause eye diseases or respiratory problems and infiltrate even deep blood vessels in the brain, it is important to predict PM2.5. However, it is difficult to predict PM2.5 because there is no clear explanation yet regarding the creation and the movement of PM2.5. Thus, prediction methods which not only predict PM2.5 accurately but also have the interpretability of the result are needed. To predict hourly PM2.5 of Seoul city, we propose a method using random forest with the adjusted bootstrap number from the time series ground data preprocessed on different sources. With this method, the prediction model can be trained uniformly on hourly information and the result has the interpretability. To evaluate the prediction performance, we conducted comparative experiments. As a result, the performance of the proposed method was superior against other models in all labels. Also, the proposed method showed the importance of the variables regarding the creation of PM2.5 and the effect of China.

• Fire Science and Engineering
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• v.29 no.2
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• pp.84-91
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• 2015

The purpose of this study is to suggest the reasonable model of the caliber in suction nozzle, the pressure of suction nozzle, and the flow rate about foam system of line proportioner type using in the pumpcar. To test this, the experimental study was accomplished on the ground of the standards for the Performance Certification and Product Inspection of Foam Fire-extinguishing Chemical Mixing Machine. Aqueous Film Forming Foam in 3% and pipe type air foam nozzle with line proportioner FE 40 type were used. Test result showed that the pressure of suction nozzle within the limits between 0.25 MPa and 0.35 MPa was appropriate when the caliber in suction nozzle is 4 mm. Also, the pressure of suction nozzle within the limits between 0.45 MPa and 0.60 MPa was appropriate in the higher pressure than 4 mm when the caliber in suction nozzle is 5 mm.

• Journal of Digital Convergence
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• v.17 no.12
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• pp.181-190
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• 2019

The purpose of this study is to evaluate the operational efficiency of Chinese e-commerce companies and to present measures to improve efficiency. This paper selected 16 enterprises as the research objects, from the e-commerce demonstration enterprises of the Ministry of Commerce of China in 2017-2018, to conduct an empirical study on the operating efficiency of e-commerce enterprises. By using DEA method, we selected 3 input and 2 output indicators to measure the input-output efficiency of enterprises from input-oriented. Using different model in DEA, we calculated the technical efficiency, pure technical efficiency and scale efficiency, also efficiency based on the sample of 2018 and horizontal analysis from 2016 to 2018. The analysis showed that the overall efficiency of Chinese e-commerce companies was continuously improving, and that their business capabilities and business scale were also gradually improving. Through the calculation of efficiency, we evaluated the competitiveness of the e-commerce demonstration enterprises, and explored measures to improve their management efficiency. At the same time, it put forward some reasonable suggestions to adjust the scale, and enhance the competitive advantage.

• Journal of Korea Port Economic Association
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• v.27 no.4
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• pp.73-90
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• 2011

Global companies regard the conditions of a location as one of the most crucial factors to assess the competitiveness of ports and the port hinterland, as well as emphasize creation of throughput and the importance of value added logistics in the hinterland under diffusing Supply Chain Management(SCM). This study deals with the evaluation of competitiveness in 7 hinterlands and the establishment of assessment model in hinterland. This study analyzes the importance of factors for the port hinterland competitiveness using AHP method. As a result, logistics factor, accounting for 62.3%, is shown as the relative more important factor, followed by hinterland's economy factors(27.3%) and city/policy factor(10.4%). The result implicates that measures to activate logistics factors with relatively high importance are essentially needed in order to improve the competitiveness of the hinterland of Busan New Port. Especially, it is needed to establish service routes of the port and air networks and to expand infrastructure for support. This study also assesses the competitiveness of hinterlands for the seven domestic and foreign ports based on importance of assessment factors for the hinterland competitiveness using AHP analysis. Busan(3.903) is ranked fourth behind Singapore(4.570), Hong Kong(4.357) and Shanghai(4.042) in assessment.

• Journal of Hydrogen and New Energy
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• v.24 no.1
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• pp.44-49
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• 2013

Hydrogen penetration into a metal leads to damages and mechanical degradations and its content measurement is of importance. For a precise measurement, a sample preparation procedure must be optimized through a series of studies on sample washing and drying. In this study, two-step washing with organic solvents and thermal soaking in inert gas were tried with a rod-shaped, API X65 steel sample. The samples were machined from a steel plate and then washed in acetone and etyl-alcohol for 5 minute each and dried with compressed air. After then, the samples were thermally soaked in a home-made nitrogen gas chamber during 10 minute at different heat gun temperatures from 100 to $400^{\circ}C$ and corresponding temperature range in the soaking chamber was from 77 to $266^{\circ}C$ according to the temperature calibration. Hydrogen residue in the samples was measured with a hot extraction system after each soaking step; hydrogen residue of $0.70{\pm}0.12$ wppm after the thermal soaking at $77^{\circ}C$ decayed with increase of the soaking temperature. By adopting the heat transfer model, decay behavior of the hydrogen residue was fitted into an exponential decay function of the soaking temperature. Saturated value or lower bound of the hydrogen residue was 0.36 wppm and chamber temperature required to lower the hydrogen residue about 95% of the lower bound was $360^{\circ}C$. Furthermore, a thermal desorption spectroscopy was done for the fully soaked samples at $360^{\circ}C$. Weak hydrogen peak was observed for whole temperature range and it means that hydrogen-related contaminants of the sample surface are steadily removed by heating. In addition, a broad peak found around $400^{\circ}C$ means that parts of the hydrogen residue are irreversibly trapped in the steel microstructure.

• Journal of Environmental Impact Assessment
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• v.28 no.2
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• pp.141-151
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• 2019

Korea has passed the Act on the Integrated Control of Pollutant-Discharging Facilities in 2015, and the integrated environmental management under the BAT standard is underway. To summarize the nature of integrated environmental management, it is the regulation by the integration of the management of the multi-pollutant source and the technical standard of BATs. In general, in environmental economics, regulation-based on technical standards are known to be inefficient. This paper attempts to evaluate the efficiency of BAT standards from an economic point of view. A simple multi-pollutant model demonstrates that the inefficiency of the environmental tax with imperfect information in a single pollutant situation is amplified under multi-pollutant conditions. The simultaneous introduction of BAT and IPPC can be partially explained by this logic. It is also highlighted by the strengthening of BAT standards by EU, as a countermeasure to the potential deterioration of air quality caused by the change of effective environmental taxes accompanying the fuel and emission price changes.

• Composites Research
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• v.32 no.5
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• pp.284-289
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• 2019

In the present paper, the dynamic force-moment equilibrium equations, driving power and energy equations are analyzed to formulate the equation for fuel economy(km/liter) equivalent to the driving distance (km) divided by the fuel volume (liter) of the vehicle, a selected model of gasoline powered KIA K3 (1.6v). In addition, the effects of the dynamic parameters such as speed of vehicle (V), vehicle total weight(M), rolling resistance ($C_r$) between tires and road surface, inclined angle of road (${\theta}$), as well as the aerodynamic parameters such as drag coefficient ($C_d$) of vehicle, air density(${\rho}$), cross-sectional area (A) of vehicle, wind speed ($V_w$) have been analyzed. And the possibility of alternative materials such as lightweight metal alloys, fiber reinforced plastic composite materials to replace the conventional steel and casting iron materials and to reduce the weight of the vehicle has been investigated by Ashby's material index method. Through studies, the following results were obtained. The most influencing parameters on the fuel economy at high speed zone (100 km/h) were V, the aerodynamic parameters such as $C_d$, A, ${\rho}$, and $C_r$ and M. While at low speed zone (60 km/h), they are, in magnitude order, dynamic parameters such as V, M, $C_r$ and aerodynamic ones such as $C_d$, A, and ${\rho}$, respectively.

• Journal of the Korea Concrete Institute
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• v.27 no.4
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• pp.427-434
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• 2015

The objective of this study is to establish an rational mixture-proportioning procedure for low-$CO_2$ concrete using supplementary cementitious materials (SCMs) achieving the targeted $CO_2$ reduction ratio as well as the conventional requirements such as initial slump, air content, and 28-day compressive strength of concrete. To evaluate the effect of SCM level on the $CO_2$ emission and compressive strength of concrete, a total of 12537 data sets were compiled from the available literature and ready-mixed concrete plants. The amount of $CO_2$ emission of concrete was assessed under the system boundary from cradle to concrete production stage at a ready-mixed concrete plant. Based on regression analysis using the established database, simple equations were proposed to determine the mixture proportions of concrete such as the type and level of SCMs, water-to-binder ratio, and fine aggregate-to-total aggregate ratio. Furthermore, the $CO_2$ emissions for a given concrete mixture can be straightforwardly calculated using the proposed equations. Overall, the developed mixture-proportioning procedure is practically useful for determining the initial mixture proportions of low-$CO_2$ concrete in the ready-mixed concrete field.