• Journal of Ginseng Research
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• v.47 no.1
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• pp.81-88
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• 2023

Background: Air pollution has led to an increased exposure of all living organisms to fine dust. Therefore, research efforts are being made to devise preventive and therapeutic remedies against fine dust-induced chronic diseases. Methods: Research of the respiratory protective effects of KRG extract in a particulate matter (PM; aerodynamic diameter of <4 ㎛) plus diesel exhaust particle (DEP) (PM4+D)-induced airway inflammation model. Nitric oxide production, expression of pro-inflammatory mediators and cytokines, and IRAK-1, TAK-1, and MAPK pathways were examined in PM4-stimulated MH-S cells. BALB/c mice exposed to PM4+D mixture by intranasal tracheal injection three times a day for 12 days at 3 day intervals and KRGE were administered orally for 12 days. Histological of lung and trachea, and immune cell subtype analyses were performed. Expression of pro-inflammatory mediators and cytokines in bronchoalveolar lavage fluid (BALF) and lung were measured. Immunohistofluorescence staining for IRAK-1 localization in lung were also evaluated. Results: KRGE inhibited the production of nitric oxide, the expression of pro-inflammatory mediators and cytokines, and expression and phosphorylation of all downstream factors of NF-κB, including IRAK-1 and MAPK/AP1 pathway in PM4-stimulated MH-S cells. KRGE suppressed inflammatory cell infiltration and number of immune cells, histopathologic damage, and inflammatory symptoms in the BALF and lungs induced by PM4+D; these included increased alveolar wall thickness, accumulation of collagen fibers, and TNF-α, MIP2, CXCL-1, IL-1α, and IL-17 cytokine release. Moreover, PM4 participates induce alveolar macrophage death and interleukin-1α release by associating with IRAK-1 localization was also potently inhibited by KRGE in the lungs of PM4+D-induced airway inflammation model. KRGE suppresses airway inflammatory responses, including granulocyte infiltration into the airway, by regulating the expression of chemokines and inflammatory cytokines via inhibition of IRAK-1 and MAPK pathway. Conclusion: Our results indicate the potential of KRGE to serve as an effective therapeutic agent against airway inflammation and respiratory diseases.

• The Transactions of the Korean Institute of Electrical Engineers A
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• v.48 no.9
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• pp.1147-1153
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• 1999

The attitude control of a double inverted pendulum with a periodical disturbance at link top is dealt in this paper. The proposed system is consisted of the double inverted pendulum and a disturbing link; a triple inverted pendulum with two motors. The lower link is hinged on the plate to free for rotation in the vertical plane. The upper link is connected to the lower link through a DC motor. The DC motor is used to control the posture of the pendulum by adjusting the position of the upper link. The periodical disturbance can be generated by the additional like attached at the end of link 2 through another DC motor, which is the modeling of a posture for a biped supporting with one leg. The motor for the joint simulates the knee joint(or hip joint) and the disturbance for the legs moving in air. The algorithm for controlling the proposed inverted pendulum which is regarded as a virtual double inverted pendulum with a periodic disturbance, is consisted of a state feedback control and a fuzzy logic controller connected in parallel. The fuzzy controller keeps the center of gravity of the biped within the specified range through the nonlinear feedback compensator. The state feedback control takes over the role to maintain a desired posture regardless the disturbance at the link top. Simulations with a mathematical model and experiments are conducted to show the validity of the proposed controller.

• Proceedings of the KIEE Conference
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• 1998.07g
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• pp.2309-2311
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• 1998

The attitude control of a double inverted pendulum with a periodical disturbance at link top is dealt in this paper. The proposed system is consisted of the double inverted pendulum and a disturbance link. The lower link is hinged on the plate to free for rotation in the vertical plane. The upper link is connected to the lower link through a DC motor. The DC motor is used to control the posture of the pendulum by adjusting the position of the upper link. The periodical disturbance can be generated by the additional link attached at the end of link 2 through another DC motor, which is the modeling of a posture for a biped supporting with one leg. The motor for the joint simulates the knee joint(or hip joint) and the disturbance for the legs moving in air. The algorithm for controlling a proposed inverted pendulum is consisted of a state feedback control and a fuzzy logic controller. The fuzzy controller keeps the center of gravity of the biped within the specified range through the nonlinear feedback compensator. The state feedback control takes over the role to maintain a desired posture regardless the disturbance at the link top. In these case, the change of the angle and COG of an upper link is compensated with on-line. Simulations with a mathematical model are conducted to show the validity of the proposed controller.

• Journal of the Korean Society for Precision Engineering
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• v.25 no.12
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• pp.117-124
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• 2008

In early design stage, the simulation of interior noise is useful for the enhancement of the noise, vibration and harshness (NVH) performance in a vehicle. The traditional transfer path analysis (TPA) technology cannot simulate the interior noise since it uses the experimental method. In order to solve this problem, in this paper, the hybrid TPA is developed as the novel approach. The hybrid TPA uses the simulated excitation force as the input force, which excites the flexible body of a car at the mount point, while the traditional TPA uses the measured force. This simulated force is obtained by numerical analysis for the FE (finite element) model of a powertrain. The interior noise is predicted by multiplying the simulated force by the vibro-acoustic transfer function (VATF) of the vehicle. The VATF is the acoustic response in the compartment of a car to the input force at the mount point of the powertrain in the flexible car body. The trend of the predicted interior noise based on the hybrid TPA very well corresponds to the measured interior noise, although there is some difference due to not only the experimental error and the simulation error but also the effect of the air-borne path.

• Journal of the Korean Institute of Landscape Architecture
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• v.27 no.2
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• pp.69-79
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• 1999

This study identifies the features of landscape elements on the fifteen districts with the idea of land use area and visual quantity of pictures by analyzing the air photo. Therefore, the sensibility of observer is comprehended through simulating the landscape evaluation and the landscape preference with using slide film. The study is divided into three periods to understand the transition of rural landscape as the social and cultural environments have been changed. The first period is the New Community Movement which affected the rapid change of social and cultural environments. The second and third periods are the prior and post time at the rearrangement of administration district in the Tae-Jeon Broad City. The result of this study is explained below part; 1. The transition of rural landscape has been occurred as the land use pattern has been altered. The change of pattern has affected an increase of the natural space and the structure change of agricultural productive space. 2. In the regression analysis, the regression model of landscape preference and land use ratio show; Landscape preference = 3.632 - 11.618 (Residential Area) - 4.227 (Equipped Farm). The explanation variables defined as Residential Area and Equipped Farm, and the relationship of those factors shows negative. Therefore, the increase of other building will make the rural landscape lower and worse.

• The Transactions of the Korean Institute of Electrical Engineers C
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• v.51 no.8
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• pp.354-360
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• 2002

The partial discharge detecting method using the ultrasonic technique has been investigated to monitor the insulation ageing of a transformer. However, the result of the studies on the ultrasonic technique for detecting of partial discharge in the operating transformer is not enough yet to utilize. This paper presents the analysis of the ultrasonic signals due to the partial discharge in a model transformer and the corona in air at a shielded high voltage room. In addition, the ultrasonic signals due to the vibration from the core, operation of the cooling pump, the fan and the OLTC at the 345㎸ power transformer, were analyzed and corona noise from overhead transmission line in 345㎸ substation were measured to remove the electrical and mechanical noises from the transformer. Furthermore, ultrasonic signal due to the partial discharge in the 154㎸ power transformer with in $C_2$$H_2$ gas warning condition was measured. The inside of the transformer was examined with care. which confirms the existence of the partial discharge source.

• Wind and Structures
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• v.9 no.1
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• pp.23-35
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• 2006

The effect of buildings on flow in urban canopy is one of the most important problems in local/micro-scale meteorology. A large eddy simulation model is used to simulate the flow structure in an urban neighborhood and the bulk effect of the buildings on surrounding flows is analyzed. The results demonstrate that: (a) The inflow conditions affect the detailed flow characteristics much in the building group, including: the distortion or disappearance of the wake vortexes, the change of funneling effect area and the change of location, size of the static-wind area. (b) The bulk effect of the buildings leads to a loss of wind speed in the low layer where height is less than four times of the average building height, and this loss effect changes little when the inflow direction changes. (c) In the bulk effect to environmental fields, the change of inflow direction affects the vertical distribution of turbulence greatly. The peak value of the turbulence energy appears at the height of the average building height. The attribution of fluctuations of different components to turbulence changes greatly at different height levels, in the low levels the horizontal speed fluctuation attribute mostly, while the vertical speed fluctuation does in high levels.

• Transactions of Materials Processing
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• v.28 no.5
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• pp.266-274
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• 2019

Metal sealing is used to connecting the parts between valves and fuel pipes for a FCEV which utilizes hydrogen gas of 700 bar. Instead of general carbon steel, stainless steel is the primary material used to manufacture fuel pipes due to hydrogen embrittlement. The shape of deformation between metals is an important factor on the air-tightness of the metal to metal contact. Since the stainless steel pipe is hardened using the plastic forming during the tip shaping stage, this work hardening could have an effect on the deformed shape and characteristics of contact surfaces in fastening of pipes. In this paper, the deformation history of the pipe model was considered in order to analyze the hydrogen-tightness on the metal sealing part. The contact distance and the forward displacement for fastening were compared using experimental results and the simulation results. The simulation of the effect of material change on the fitting body demonstrated that the hardness or the strength of the formed tip of the pipe was designed to a proper valued level since the characteristics of the contact surface was exhibited better when the strength of the pipe was lower than that of the fitting body.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.22 no.6
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• pp.1010-1017
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• 2013

Two-axial electrodynamic forces generated on a conductive plate by a partially shielded magnet wheel are strongly coupled through the rotational speed of the wheel. To control the spatial position of the plate using magnet wheels, the forces should be handled independently. Thus, three methods are proposed in this paper. First, considering that a relative ratio between two forces is independent of the length of the air-gap from the top of the wheel, it is possible to indirectly control the in-plane position of the plate using only the normal forces. In doing so, the control inputs for in-plane motion are converted into the target positions for out-of-plane motion. Second, the tangential direction of the open area of the shield plate and the rotational speed of the wheel become the new control variables. Third, the absolute magnitude of the open area is varied, instead of rotating the open area. The forces are determined simply by using a linear controller, and the relative ratio between the forces creates a unique wheel speed. The above methods were verified experimentally.

• Proceedings of the KSME Conference
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• 2003.04a
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• pp.1572-1577
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• 2003

High-power pulsed laser ablation under atmospheric pressure is studied utilizing numerical and experimental methods with emphasis on recondensation ratio, and the dynamics of the laser induced vapor flow. In the numerical calculation, the temperature pressure, density and vaporization flux on a solid substrate are first obtained by a heat-transfer computation code based on the enthalpy method, and then the plume dynamics is calculated by using a commercial CFD package. To confirm the computation results, the probe beam deflection technique was utilized for measuring the propagation of a laser induced shock wave. Discontinuities of properties and velocity over the Knudsen layer were investigated. Related with the analysis of the jump condition, the effect of the recondesation ratio on the plume dynamics was examined by comparing the pressure, density, and mass fraction of ablated aluminum vapor. To consider the effect of mass transfer between the ablation plume and air, unlike the most previous investigations, the equation of species conservation is simultaneously solved with the Euler equations. Therefore the numerical model computes not only the propagation of the shock front but also the distribution of the aluminum vapor. To our knowledge, this is the first work that employed a commercial CFD code in the calculation of pulsed ablation phenomena.